Protein-protein interaction for H2AFX

EMBED not supported by browser.
Nodes, degree=1 Nodes, degree=2


Protein-protein interaction data for gene H2AFX

Degree = 1
Interactor A Interactor B Experimental method Source Pubmed
H2AFXNBN-HPRD,BioGRID11110662 
H2AFXTP53BP1-HPRD,BioGRID12697768 
H2AFXMDC1-HPRD,BioGRID12607005 |14519663 
H2AFXBARD1Reconstituted ComplexBioGRID11927591 |12485996 
H2AFXALG9-HPRD14519663 
H2AFXBRCA1Co-localization; Reconstituted ComplexBioGRID10959836 |11927591 
|12485996 
H2AFXRAD50Co-localizationBioGRID10959836 
H2AFXRAD51Co-localizationBioGRID10959836 
H2AFXBLMAffinity Capture-Western; Co-localizationBioGRID15364958 
H2AFXATMATM phosphorylates the carboxy terminus of H2AX.BIND15064416 

Degree = 2
Interactor A Interactor B Experimental method Source Pubmed
NBNXRCC5NBS1 interacts with XRCC5 (Ku80).BIND15758953 
NBNMSH6Co-purificationBioGRID10783165 
NBNMLH1Co-purificationBioGRID10783165 
NBNCDK9-HPRD8170997 |8870681 
|9258347 
NBNFANCD2Affinity Capture-WesternBioGRID12447395 
NBNATF2ATF2 interacts with Nbs1.BIND15916964 
NBNMSH2Co-purificationBioGRID10783165 
NBNPRKDCNBS1 interacts with PRKDC (DNA-PKc).BIND15758953 
NBNTERF2-HPRD,BioGRID10888888 
NBNMRE11A-HPRD9705271 |10426999 
|11238951 
NBS1 interacts with MRE11A (Mre11).BIND15758953 
Affinity Capture-Western; Co-localization; Co-purification; Two-hybridBioGRID9705271 |10783165 
|11238951 |12679336 
|18458108 
Mre11 interacts with Nbs1BIND9590181 
NBNATRProtein-peptideBioGRID10608806 
NBS1 interacts with ATR.BIND15758953 
NBNRFC1Co-purificationBioGRID10783165 
NBNTERF1-HPRD,BioGRID10913111 
NBNATRProtein-peptideBioGRID10608806 
NBS1 interacts with ATR.BIND15758953 
NBNMRE11A-HPRD9705271 |10426999 
|11238951 
NBS1 interacts with MRE11A (Mre11).BIND15758953 
Affinity Capture-Western; Co-localization; Co-purification; Two-hybridBioGRID9705271 |10783165 
|11238951 |12679336 
|18458108 
Mre11 interacts with Nbs1BIND9590181 
NBNMRE11A-HPRD9705271 |10426999 
|11238951 
NBS1 interacts with MRE11A (Mre11).BIND15758953 
Affinity Capture-Western; Co-localization; Co-purification; Two-hybridBioGRID9705271 |10783165 
|11238951 |12679336 
|18458108 
Mre11 interacts with Nbs1BIND9590181 
NBNMRE11A-HPRD9705271 |10426999 
|11238951 
NBS1 interacts with MRE11A (Mre11).BIND15758953 
Affinity Capture-Western; Co-localization; Co-purification; Two-hybridBioGRID9705271 |10783165 
|11238951 |12679336 
|18458108 
Mre11 interacts with Nbs1BIND9590181 
NBNXRCC4Two-hybridBioGRID18458108 
TP53BP1DCLRE1CArtemis interacts with 53BP1.BIND15574327 
TP53BP1E2F1Affinity Capture-Western; Reconstituted ComplexBioGRID8896460 
TP53BP1TP53Affinity Capture-Western; Co-crystal Structure; Co-localization; Reconstituted Complex; Two-hybridBioGRID8016121 |11877378 
|12110597 |12351827 
|14978302 |15364958 
|15611139 
-HPRD8016121 |12110597 
TP53BP1CHEK1Co-localizationBioGRID15364958 
TP53BP1TP53Affinity Capture-Western; Co-crystal Structure; Co-localization; Reconstituted Complex; Two-hybridBioGRID8016121 |11877378 
|12110597 |12351827 
|14978302 |15364958 
|15611139 
-HPRD8016121 |12110597 
TP53BP1DCTN1Affinity Capture-WesternBioGRID15611139 
TP53BP1CHEK2Affinity Capture-WesternBioGRID17525332 
TP53BP1NFKB1Affinity Capture-WesternBioGRID10646849 
TP53BP1DYNLL1Affinity Capture-Western; Protein-peptide; Two-hybridBioGRID15611139 
TP53BP1PAXIP1Affinity Capture-Western; Reconstituted ComplexBioGRID14576432 |15456759 
TP53BP1TFDP1Reconstituted ComplexBioGRID8896460 
TP53BP1RPA2Affinity Capture-MS; Affinity Capture-WesternBioGRID15856006 
TP53BP1RPA1Affinity Capture-MS; Affinity Capture-WesternBioGRID15856006 
TP53BP1NEK1NEK1 interacts with 53BP1.BIND14690447 
TP53BP1DCLRE1AAffinity Capture-WesternBioGRID12446782 
MDC1CHEK2-HPRD,BioGRID12551934 |12607004 
MDC1GATA4Protein-peptideBioGRID14578343 
MDC1TP53-HPRD,BioGRID14519663 
MDC1HDAC8Protein-peptideBioGRID14578343 
MDC1MRE11AAffinity Capture-MS; Affinity Capture-WesternBioGRID14519663 
MDC1CENPC1Protein-peptideBioGRID14578343 
MDC1HDAC10Protein-peptideBioGRID14578343 
MDC1SMC1A-HPRD12607005 
MDC1POLR2AProtein-peptideBioGRID14578343 
MDC1MDM2Protein-peptideBioGRID14578343 
MDC1WRNProtein-peptideBioGRID14578343 
BARD1EWSR1-HPRD,BioGRID12183411 
BARD1XRCC6BARD1 interacts with XRCC6 (Ku70).BIND15782130 
BARD1MED17Co-purificationBioGRID12154023 
BARD1TCERG1-HPRD15383276 
BARD1ING5-HPRD15383276 
BARD1NFKBIATwo-hybridBioGRID10362352 
BARD1UBE2D1Reconstituted ComplexBioGRID11278247 |11927591 
|12438698 |12485996 
|12887909 |12890688 
|14636569 |15184379 
BARD1FANCD2Co-localization; Reconstituted ComplexBioGRID12887909 
BARD1MSH6Reconstituted ComplexBioGRID11498787 
BARD1UBE2D3-HPRD12732733 
BARD1UBE2D2Reconstituted ComplexBioGRID12431996 
BARD1POU2F1-HPRD11777930 
BARD1MSH3Reconstituted ComplexBioGRID11498787 
BARD1NPM1Affinity Capture-MS; Affinity Capture-Western; Reconstituted ComplexBioGRID15184379 
BARD1UBA1Reconstituted ComplexBioGRID11278247 |11927591 
|12431996 |12438698 
|12485996 |12887909 
|15184379 
BARD1E2F1E2F1 interacts with the BARD1 promoter.BIND11799067 
BARD1TP53Affinity Capture-MS; Affinity Capture-WesternBioGRID14636569 
TP53 (p53) interacts with BARD1.BIND15782130 
BARD1E2F4E2F4 interacts with the BARD1 promoter region.BIND11799067 
BARD1UBE3AReconstituted ComplexBioGRID12890688 
BARD1RELAAffinity Capture-WesternBioGRID12700228 
BARD1RBBP8-HPRD,BioGRID10764811 
BARD1BREAffinity Capture-MS; Affinity Capture-WesternBioGRID14636569 
BARD1MSH2-HPRD,BioGRID11498787 
BARD1UBE2L3-HPRD12732733 
BARD1BRCA2Co-purification; Reconstituted ComplexBioGRID14636569 
BARD1TP53Affinity Capture-MS; Affinity Capture-WesternBioGRID14636569 
TP53 (p53) interacts with BARD1.BIND15782130 
BARD1CSTF1-HPRD,BioGRID10477523 |11257228 
BARD1XISTCo-localizationBioGRID12419249 
BARD1POLR2A-HPRD12154023 
BARD1BCL3-HPRD,BioGRID10362352 
BARD1CSTF2Affinity Capture-Western; Co-purificationBioGRID10477523 |11257228 
BARD1BRCC3Affinity Capture-MS; Affinity Capture-WesternBioGRID14636569 
BARD1HIST2H2ABReconstituted ComplexBioGRID11927591 
BARD1ZHX1-HPRD15383276 
BRCA1CSTF2Affinity Capture-Western; Co-purificationBioGRID10477523 |11257228 
BRCA1JUNBBRCA1 interacts with JunB.BIND12080089 
-HPRD,BioGRID12080089 
BRCA1CSNK2BReconstituted Complex; Two-hybridBioGRID10403822 
BRCA1 is phosphorylated by Casein kinase 2 through a physical interaction with CSNK2BBIND10403822 
BRCA1RFC1-HPRD,BioGRID10783165 
BRCA1APLP2Far WesternBioGRID11746496 
BRCA1TOP2ATOP2A (Topo II) interacts with BRCA1BIND15965487 
BRCA1BAP1-HPRD9528852 
BRCA1RB1-HPRD,BioGRID10220405 
BRCA1 interacts with Rb.BIND10518542 
BRCA1UBE2D3-HPRD12732733 
BRCA1PRKDCProtein-peptideBioGRID10608806 
BRCA1STAT3-HPRD11163768 
BRCA1NUP153Protein-peptideBioGRID14578343 
BRCA1XISTCo-localizationBioGRID12419249 |15065664 
BRCA1MAP3K3Affinity Capture-Western; Two-hybridBioGRID15205325 
BRCA1 interacts with MEKK3.BIND15205325 
BRCA1RBBP7BRCA1 interacts with RbAp46.BIND10220405 
-HPRD,BioGRID10220405 
BRCA1UBE2L3-HPRD,BioGRID12732733 
BRCA1MSH3Protein-peptide; Reconstituted ComplexBioGRID11498787 |14578343 
BRCA1CDS1Reconstituted ComplexBioGRID12438214 
BRCA1NCOA3Protein-peptideBioGRID14578343 
BRCA1UBE2D1Reconstituted ComplexBioGRID11278247 |11927591 
|12438698 |12485996 
|12732733 |12887909 
|12890688 |14636569 
|14638690 |15184379 
BRCA1NPM1Affinity Capture-MS; Affinity Capture-Western; Reconstituted ComplexBioGRID15184379 
BRCA1NMI-HPRD,BioGRID11916966 
BRCA1 interacts with Nmi.BIND11916966 
BRCA1HDAC2-HPRD,BioGRID10220405 
BRCA1 interacts with HDAC2BIND10220405 
BRCA1CCNA1BRCA1 associates with Cyclin ABIND9244350 |10373534 
Reconstituted ComplexBioGRID9244350 
BRCA1CDK8Co-purificationBioGRID9159119 
BRCA1CCNA2-HPRD,BioGRID9244350 |10373534 
BRCA1SMARCC2Co-purificationBioGRID10943845 
BRCA1CDC2-HPRD,BioGRID9244350 
BRCA1JUNBRCA1 interacts with c-Jun.BIND12080089 
-HPRD,BioGRID12080089 
BRCA1HDAC1BRCA1 interacts with HDAC1BIND10220405 
-HPRD,BioGRID10220405 
BRCA1E2F1BRCA1 associates with E2F-1BIND9244350 
-HPRD9244350 
BRCA1NCOA2Protein-peptide; Reconstituted ComplexBioGRID11085509 |14578343 
BRCA1HIST2H2ACReconstituted ComplexBioGRID11927591 
BRCA1HIST2H3CCo-localizationBioGRID12419249 
BRCA1MED23Affinity Capture-MSBioGRID15208681 
BRCA1E2F4BRCA1 associates with E2F-4BIND9244350 
-HPRD,BioGRID9244350 
BRCA1POLR2A-HPRD4506230 |9159119 
|12154023|10725406 
-HPRD4506230 |9159119 
|12154023 
Affinity Capture-Western; Co-purificationBioGRID9159119 |11504724 
|12955082 |14506230 
BRCA1MED17Affinity Capture-MS; Co-purificationBioGRID11504724 |12154023 
|15208681 
BRCA1PCTK1Two-hybridBioGRID9738006 
BRCA1NFKB1-HPRD12700228 
BRCA1ATRBRCA1 physically and functionally interacts with ATR during genotoxic stressBIND11016625 |11278964 
Affinity Capture-Western; Protein-peptide; Reconstituted ComplexBioGRID10608806 |11016625 
|11114888 |11278964 
BRCA1NUFIP1Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID15107825 
BRCA1 interacts with NUFIP.BIND15107825 
BRCA1CCND1-HPRD,BioGRID9244350 
BRCA1 associates with Cyclin D1BIND9244350 
BRCA1HSPA8Two-hybridBioGRID9738006 
BRCA1MSH6BRCA1 associates with MSH6.BIND10783165 |11498787 
-HPRD,BioGRID11498787 
BRCA1CREBBP-HPRD,BioGRID10655477 
CBP interacts with BRCA1. This interaction was modelled on a demonstrated interaction between human BRCA1 and mouse CBP.BIND10655477 
BRCA1RBL1Co-localization; Reconstituted ComplexBioGRID11521194 
BRCA1ELK1-HPRD11313879 
BRCA1RBL2Co-localization; Reconstituted ComplexBioGRID11521194 
BRCA1STAT1-HPRD,BioGRID10792030 
BRCA1BRIP1Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Protein-peptide; Reconstituted ComplexBioGRID11877378 |14576433 
|14578343 |15133502 
|15208681 |15242590 
-HPRD11301010 
BRCA1SMAD2BRCA1 interacts with Smad2. This interaction was modeled on a demonstrated interaction between BRCA1 from human and Smad2 from an unspecified species.BIND15735739 
BRCA1CDK4-HPRD,BioGRID9244350 
BRCA1 associates with CDK4BIND9244350 
BRCA1GTF2F1Co-purificationBioGRID9159119 
BRCA1GTF2E1Co-purificationBioGRID9159119 
BRCA1RELA-HPRD,BioGRID12700228 
BRCA1TUBG1-HPRD,BioGRID9789027 |11691781 
BRCA1SMARCA2Affinity Capture-WesternBioGRID15034933 
BRCA1AURKAAffinity Capture-Western; Reconstituted ComplexBioGRID14990569 
BRCA1TP53BRCA1a interacts with p53.BIND9926942 
BRCA1 physically associates with p53 and stimulates its transcriptional activityBIND9582019 
-HPRD,BioGRID9482880 
BRCA1MAP4K4Protein-peptideBioGRID14578343 
BRCA1KPNA2Two-hybridBioGRID8955125 
-HPRD9497340 
BRCA1CSNK2A1-HPRD,BioGRID10403822 
BRCA1CDK4-HPRD,BioGRID9244350 
BRCA1 associates with CDK4BIND9244350 
BRCA1MYC-HPRD,BioGRID9788437 
BRCA1 association with c-Myc, a proto-oncogene that is implicated in tumorigenesis, embryonic development and apoptosis, inhibits its transcriptional and transforming activity in cells.BIND9788437 
BRCA1CSTF1Reconstituted ComplexBioGRID11257228 
BRCA1AR-HPRD,BioGRID11016951 |11085509 
BRCA1VCP-HPRD,BioGRID10855792 
BRCA1MLH1-HPRD,BioGRID10783165 
BRCA1MED24Affinity Capture-MS; Affinity Capture-WesternBioGRID15208681 
BRCA1BRAP-HPRD,BioGRID9497340 
BRCA1SP1-HPRD10720440 
BRCA1 interacts with Sp1.BIND12706836 
Affinity Capture-WesternBioGRID12706836 
BRCA1NMI-HPRD,BioGRID11916966 
BRCA1 interacts with Nmi.BIND11916966 
BRCA1FANCABRCA1 interacts with FANCA.BIND12354784 
-HPRD,BioGRID12354784 
BRCA1ATF1-HPRD,BioGRID10945975 
BRCA1BRCA2-HPRD,BioGRID9774970 
BRCA1 interacts with BRCA2.BIND9774970 
BRCA1TP53BRCA1a interacts with p53.BIND9926942 
BRCA1 physically associates with p53 and stimulates its transcriptional activityBIND9582019 
-HPRD,BioGRID9482880 
BRCA1CDK2BRCA1 associates with CDK2BIND9244350 |10373534 
Affinity Capture-Western; Reconstituted ComplexBioGRID8764100 |9244350 
|10373534 
BRCA1COBRA1Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID11739404 
-HPRD12612062 
BRCA1LMO4-HPRD,BioGRID11751867 
The LIM domain protein LMO4 interacts with BRCA1BIND11751867 
BRCA1NFYA-HPRD,BioGRID11777930 
BRCA1 interacts with NF-YABIND11777930 
BRCA1MED1BRCA1 interacts with TRAP220.BIND15208681 
Affinity Capture-MS; Affinity Capture-Western; Reconstituted ComplexBioGRID15208681 
BRCA1E2F1BRCA1 associates with E2F-1BIND9244350 
-HPRD9244350 
BRCA1PEG3Far WesternBioGRID11746496 
BRCA1BRCC3Affinity Capture-MS; Affinity Capture-Western; Co-purificationBioGRID14636569 
BRCA1RBBP8-HPRD9738006 |10196224 
Affinity Capture-Western; Protein-peptide; Reconstituted Complex; Two-hybridBioGRID9738006 |9811458 
|10196224 |10764811 
|10910365 |11689934 
|14578343 
BRCA1 interacts with CtIP.BIND9811458 
BRCA1POLR2A-HPRD4506230 |9159119 
|12154023|10725406 
-HPRD4506230 |9159119 
|12154023 
Affinity Capture-Western; Co-purificationBioGRID9159119 |11504724 
|12955082 |14506230 
BRCA1TP53BRCA1a interacts with p53.BIND9926942 
BRCA1 physically associates with p53 and stimulates its transcriptional activityBIND9582019 
-HPRD,BioGRID9482880 
BRCA1JUND-HPRD,BioGRID12080089 
BRCA1 interacts with JunD.BIND12080089 
BRCA1ZNF350-HPRD,BioGRID11090615 
BRCA1RBBP8-HPRD9738006 |10196224 
Affinity Capture-Western; Protein-peptide; Reconstituted Complex; Two-hybridBioGRID9738006 |9811458 
|10196224 |10764811 
|10910365 |11689934 
|14578343 
BRCA1 interacts with CtIP.BIND9811458 
BRCA1POLR2K-HPRD10725406 
BRCA1CREBBP-HPRD,BioGRID10655477 
CBP interacts with BRCA1. This interaction was modelled on a demonstrated interaction between human BRCA1 and mouse CBP.BIND10655477 
BRCA1FLNA-HPRD11602572 
BRCA1ESR1-HPRD10334989 
Affinity Capture-Western; Co-localization; Reconstituted ComplexBioGRID11244506 |11493692 
|11782371 |12400015 
BRCA1HDAC1BRCA1 interacts with HDAC1BIND10220405 
-HPRD,BioGRID10220405 
BRCA1UBBBRCA1 interacts with Ub. This interaction was modelled on a demonstrated interaction between human BRCA1 and Ub from an unspecified source.BIND11320250 
BRCA1CCNB1-HPRD,BioGRID9244350 
BRCA1 is a tyrosine phosphoprotein that associates with Cyclin B1BIND9244350 
BRCA1MSH2-HPRD,BioGRID11498787 
BRCA1 interacts with MSH2 in the absence of ADP-MSH2 interaction.BIND10783165 
BRCA1DHX9-HPRD9662397|12592385 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID9662397 |12592385 
BRCA1RPL31Far Western; Reconstituted ComplexBioGRID11746496 
BRCA1EP300-HPRD,BioGRID10655477 
p300 interacts with BRCA1.BIND10655477 
BRCA1MSH6BRCA1 associates with MSH6.BIND10783165 |11498787 
-HPRD,BioGRID11498787 
BRCA1COBRA1Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID11739404 
-HPRD12612062 
BRCA1KPNA2Two-hybridBioGRID8955125 
-HPRD9497340 
BRCA1JUND-HPRD,BioGRID12080089 
BRCA1 interacts with JunD.BIND12080089 
BRCA1EP300-HPRD,BioGRID10655477 
p300 interacts with BRCA1.BIND10655477 
BRCA1SMARCC1Co-purificationBioGRID10943845 
BRCA1JAK1-HPRD,BioGRID11163768 
BRCA1SMARCD2Co-purificationBioGRID10943845 
BRCA1FANCD2Co-localization; Reconstituted Complex; Two-hybridBioGRID12887909 |14499622 
-HPRD11239454 
BRCA1SMAD3BRCA1 interacts with Smad3.BIND15735739 
BRCA1WNT2BFar WesternBioGRID11746496 
BRCA1BREAffinity Capture-MS; Affinity Capture-Western; Co-purificationBioGRID14636569 
BRCA1MED21-HPRD,BioGRID9159119 
BRCA1ETS1Reconstituted ComplexBioGRID11313879 
BRCA1E2F4BRCA1 associates with E2F-4BIND9244350 
-HPRD,BioGRID9244350 
BRCA1MED13Affinity Capture-MSBioGRID15208681 
BRCA1ELK4Affinity Capture-Western; Reconstituted ComplexBioGRID11313879 
BRCA1SP1-HPRD10720440 
BRCA1 interacts with Sp1.BIND12706836 
Affinity Capture-WesternBioGRID12706836 
BRCA1CCNE1Affinity Capture-WesternBioGRID17525332 
BRCA1PPP1CAAffinity Capture-Western; Reconstituted ComplexBioGRID12438214 
BRCA1ACACA-HPRD,BioGRID12360400 
BRCA1 interacts with acetyl-CoA carboxylase.BIND12360400 
BRCA1ABL1Affinity Capture-WesternBioGRID12024016 
BRCA1NFYA-HPRD,BioGRID11777930 
BRCA1 interacts with NF-YABIND11777930 
BRCA1ORC3LAffinity Capture-WesternBioGRID17525332 
BRCA1CCNB1-HPRD,BioGRID9244350 
BRCA1 is a tyrosine phosphoprotein that associates with Cyclin B1BIND9244350 
BRCA1BRIP1Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Protein-peptide; Reconstituted ComplexBioGRID11877378 |14576433 
|14578343 |15133502 
|15208681 |15242590 
-HPRD11301010 
BRCA1FANCD2Co-localization; Reconstituted Complex; Two-hybridBioGRID12887909 |14499622 
-HPRD11239454 
BRCA1LMO4-HPRD,BioGRID11751867 
The LIM domain protein LMO4 interacts with BRCA1BIND11751867 
BRCA1CDK5Reconstituted ComplexBioGRID9244350 
BRCA1KIF1BProtein-peptideBioGRID14578343 
BRCA1JAK2-HPRD,BioGRID11163768 
BRCA1CHEK2-HPRD,BioGRID10724175 
BRCA1DHX9-HPRD9662397|12592385 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID9662397 |12592385 
BRCA1CTBP1-HPRD,BioGRID10196224 
BRCA1USF2-HPRD,BioGRID14502648 
BRCA1CTCFLProtein-peptideBioGRID14578343 
BRCA1CCND1-HPRD,BioGRID9244350 
BRCA1 associates with Cyclin D1BIND9244350 
BRCA1RB1-HPRD,BioGRID10220405 
BRCA1 interacts with Rb.BIND10518542 
BRCA1UBE3AReconstituted ComplexBioGRID12890688 
BRCA1MAP3K3Affinity Capture-Western; Two-hybridBioGRID15205325 
BRCA1 interacts with MEKK3.BIND15205325 
BRCA1DNAJA3Protein-peptideBioGRID14578343 
BRCA1CSNK2BReconstituted Complex; Two-hybridBioGRID10403822 
BRCA1 is phosphorylated by Casein kinase 2 through a physical interaction with CSNK2BBIND10403822 
BRCA1BACH1-HPRD,BioGRID11301010 
BRCA1ZCCHC8Affinity Capture-WesternBioGRID17525332 
BRCA1AKT1Reconstituted ComplexBioGRID10542266 
BRCA1POU2F1Affinity Capture-WesternBioGRID11777930 
BRCA1 interacts with Oct-1.BIND11777930 
BRCA1H2AFYCo-localizationBioGRID12419249 
BRCA1RBBP4BRCA1 interacts with RbAp48.BIND10220405 
-HPRD,BioGRID10220405 
BRCA1STAT5A-HPRD,BioGRID12459499 
BRCA1ATRBRCA1 physically and functionally interacts with ATR during genotoxic stressBIND11016625 |11278964 
Affinity Capture-Western; Protein-peptide; Reconstituted ComplexBioGRID10608806 |11016625 
|11114888 |11278964 
BRCA1RBBP8-HPRD9738006 |10196224 
Affinity Capture-Western; Protein-peptide; Reconstituted Complex; Two-hybridBioGRID9738006 |9811458 
|10196224 |10764811 
|10910365 |11689934 
|14578343 
BRCA1 interacts with CtIP.BIND9811458 
BRCA1MED1BRCA1 interacts with TRAP220.BIND15208681 
Affinity Capture-MS; Affinity Capture-Western; Reconstituted ComplexBioGRID15208681 
BRCA1CLSPN-HPRD,BioGRID15096610 
BRCA1RBBP4BRCA1 interacts with RbAp48.BIND10220405 
-HPRD,BioGRID10220405 
BRCA1FANCABRCA1 interacts with FANCA.BIND12354784 
-HPRD,BioGRID12354784 
BRCA1UBA1Reconstituted ComplexBioGRID11278247 |11927591 
|12438698 |12485996 
|12887909 |14638690 
|15184379 
BRCA1ACACA-HPRD,BioGRID12360400 
BRCA1 interacts with acetyl-CoA carboxylase.BIND12360400 
BRCA1NUFIP1Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID15107825 
BRCA1 interacts with NUFIP.BIND15107825 
BRCA1SMAD4BRCA1 interacts with Smad4. This interaction was modeled on a demonstrated interaction between BRCA1 from human and Smad4 from an unspecified species.BIND15735739 
BRCA1HDAC2-HPRD,BioGRID10220405 
BRCA1 interacts with HDAC2BIND10220405 
BRCA1SMARCB1Co-purificationBioGRID10943845 
BRCA1GTF2H4Co-purificationBioGRID9159119 
BRCA1JUNBBRCA1 interacts with JunB.BIND12080089 
-HPRD,BioGRID12080089 
BRCA1FLI1Reconstituted ComplexBioGRID11313879 
BRCA1SMARCA4-HPRD,BioGRID10943845 
BRCA1BRCA2-HPRD,BioGRID9774970 
BRCA1 interacts with BRCA2.BIND9774970 
BRCA1ETS2ETS2 (Ets-2) interacts with BRCA1 promoter. This interaction was modeled on a demonstrated interaction between ETS2 from an unspecified species and BRCA1 promoter from an unspecified species.BIND12637547 
BRCA1MRE11AAffinity Capture-Western; Co-localization; Co-purification; Reconstituted ComplexBioGRID10426999 |10783165 
|11353843 |11504724 
BRCA1ESR1-HPRD10334989 
Affinity Capture-Western; Co-localization; Reconstituted ComplexBioGRID11244506 |11493692 
|11782371 |12400015 
BRCA1MYC-HPRD,BioGRID9788437 
BRCA1 association with c-Myc, a proto-oncogene that is implicated in tumorigenesis, embryonic development and apoptosis, inhibits its transcriptional and transforming activity in cells.BIND9788437 
BRCA1JUNBRCA1 interacts with c-Jun.BIND12080089 
-HPRD,BioGRID12080089 
BRCA1MSH2-HPRD,BioGRID11498787 
BRCA1 interacts with MSH2 in the absence of ADP-MSH2 interaction.BIND10783165 
BRCA1CCNA1BRCA1 associates with Cyclin ABIND9244350 |10373534 
Reconstituted ComplexBioGRID9244350 
BRCA1CDK2BRCA1 associates with CDK2BIND9244350 |10373534 
Affinity Capture-Western; Reconstituted ComplexBioGRID8764100 |9244350 
|10373534 
BRCA1POU2F1Affinity Capture-WesternBioGRID11777930 
BRCA1 interacts with Oct-1.BIND11777930 
BRCA1XRCC1-HPRD11352725 
BRCA1SMC1A-HPRD11877377 
BRCA1POLR2A-HPRD4506230 |9159119 
|12154023|10725406 
-HPRD4506230 |9159119 
|12154023 
Affinity Capture-Western; Co-purificationBioGRID9159119 |11504724 
|12955082 |14506230 
BRCA1SP1-HPRD10720440 
BRCA1 interacts with Sp1.BIND12706836 
Affinity Capture-WesternBioGRID12706836 
BRCA1FHL2Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID14550570 |14986435 
BRCA1CREB1Phenotypic EnhancementBioGRID10945975 
BRCA1ORC2LAffinity Capture-WesternBioGRID17525332 
BRCA1RBBP7BRCA1 interacts with RbAp46.BIND10220405 
-HPRD,BioGRID10220405 
RAD50MLH1Co-purificationBioGRID10783165 
RAD50TERF2IP-HPRD,BioGRID15100233 
RAD50CHEK2Affinity Capture-WesternBioGRID17525332 
RAD50MRE11AMre11 interacts with Rad50BIND9590181 
-HPRD8756642 |10888888 
Affinity Capture-Western; Co-purificationBioGRID8756642 |9705271 
|10783165 |11504724 
RAD50MRE11AMre11 interacts with Rad50BIND9590181 
-HPRD8756642 |10888888 
Affinity Capture-Western; Co-purificationBioGRID8756642 |9705271 
|10783165 |11504724 
RAD50RINT1-HPRD,BioGRID11096100 
RAD50MSH6Co-purificationBioGRID10783165 
RAD50MSH2Co-purificationBioGRID10783165 
RAD50TERF2-HPRD,BioGRID10888888 
RAD50MRE11AMre11 interacts with Rad50BIND9590181 
-HPRD8756642 |10888888 
Affinity Capture-Western; Co-purificationBioGRID8756642 |9705271 
|10783165 |11504724 
RAD50RFC1Co-purificationBioGRID10783165 
RAD50HNF4AAffinity Capture-MSBioGRID17353931 
RAD51UBE2I-HPRD,BioGRID8610150 
RAD51E2F1E2F1 interacts with the RAD51 chromatin.BIND11799066 
RAD51BRCA2Affinity Capture-MS; Affinity Capture-Western; Co-localization; Co-purification; Reconstituted Complex; Two-hybridBioGRID9126738 |9405383 
|9523196 |9560268 
|9774970 |9811893 
|11313963 |11477095 
|12408834 |12442171 
|12815053 |14580352 
|14636569 |15065660 
-HPRD9126738 |12619154 
BRCA2 interacts with RAD51.BIND9774970 
BRCA2 interacts with Rad51.BIND9774970 
BRCA2 interacts with an unspecified isoform of RAD51.BIND15800615 
RAD51VIMTwo-hybridBioGRID16169070 
RAD51DNAJA3Co-localizationBioGRID11005857 
RAD51BRCA2Affinity Capture-MS; Affinity Capture-Western; Co-localization; Co-purification; Reconstituted Complex; Two-hybridBioGRID9126738 |9405383 
|9523196 |9560268 
|9774970 |9811893 
|11313963 |11477095 
|12408834 |12442171 
|12815053 |14580352 
|14636569 |15065660 
-HPRD9126738 |12619154 
BRCA2 interacts with RAD51.BIND9774970 
BRCA2 interacts with Rad51.BIND9774970 
BRCA2 interacts with an unspecified isoform of RAD51.BIND15800615 
RAD51MSH4Co-localizationBioGRID11950880 
RAD51BCCIP-HPRD15713648 
RAD51FANCD2-HPRD12239151 
RAD51BRCA2Affinity Capture-MS; Affinity Capture-Western; Co-localization; Co-purification; Reconstituted Complex; Two-hybridBioGRID9126738 |9405383 
|9523196 |9560268 
|9774970 |9811893 
|11313963 |11477095 
|12408834 |12442171 
|12815053 |14580352 
|14636569 |15065660 
-HPRD9126738 |12619154 
BRCA2 interacts with RAD51.BIND9774970 
BRCA2 interacts with Rad51.BIND9774970 
BRCA2 interacts with an unspecified isoform of RAD51.BIND15800615 
RAD51BRCA2Affinity Capture-MS; Affinity Capture-Western; Co-localization; Co-purification; Reconstituted Complex; Two-hybridBioGRID9126738 |9405383 
|9523196 |9560268 
|9774970 |9811893 
|11313963 |11477095 
|12408834 |12442171 
|12815053 |14580352 
|14636569 |15065660 
-HPRD9126738 |12619154 
BRCA2 interacts with RAD51.BIND9774970 
BRCA2 interacts with Rad51.BIND9774970 
BRCA2 interacts with an unspecified isoform of RAD51.BIND15800615 
RAD51BRCA2Affinity Capture-MS; Affinity Capture-Western; Co-localization; Co-purification; Reconstituted Complex; Two-hybridBioGRID9126738 |9405383 
|9523196 |9560268 
|9774970 |9811893 
|11313963 |11477095 
|12408834 |12442171 
|12815053 |14580352 
|14636569 |15065660 
-HPRD9126738 |12619154 
BRCA2 interacts with RAD51.BIND9774970 
BRCA2 interacts with Rad51.BIND9774970 
BRCA2 interacts with an unspecified isoform of RAD51.BIND15800615 
RAD51CHEK1Chk1 interacts with RAD51.BIND15665856 
RAD51ABL1Affinity Capture-Western; Reconstituted ComplexBioGRID10212258 
RAD51TP53-HPRD,BioGRID8617246 |9380510 
RAD51CHD3Two-hybridBioGRID16169070 
RAD51C17orf28-HPRD10562567 
RAD51RAD51L1Co-localizationBioGRID15065660 
RAD51TIMM13Affinity Capture-MSBioGRID17353931 
RAD51RAD54B-HPRD,BioGRID10851248 
RAD51BREAffinity Capture-MS; Affinity Capture-Western; Co-purificationBioGRID14636569 
RAD51ATRXReconstituted Complex; Two-hybridBioGRID10851248 |12205100 
RAD51RAD52Affinity Capture-WesternBioGRID10212258 
RAD51XRCC2Co-localizationBioGRID15065660 
RAD51CAB39Affinity Capture-MSBioGRID17353931 
RAD51E2F4E2F4 interacts with the RAD51 chromatin.BIND11799066 
RAD51RAD51AP1-HPRD,BioGRID9396801 
RAD51SUMO1-HPRD,BioGRID8812453 |9891849 
RAD51LGTNAffinity Capture-MSBioGRID17353931 
RAD51RPA1Reconstituted ComplexBioGRID12077133 
RAD51XRCC3Co-localizationBioGRID15065660 
RAD51RAD51L3Co-localizationBioGRID15065660 
RAD51DMC1-HPRD,BioGRID10562567 
RAD51RAD54L-HPRD12205100 
RAD51RAD51CCo-localizationBioGRID15065660 
RAD51BRCC3Affinity Capture-MS; Affinity Capture-Western; Co-purificationBioGRID14636569 
BLMCASP3Biochemical ActivityBioGRID11470874 
BLMTP53BLM interacts with p53.BIND12080066 
BLM interacts with p53. This interaction was modeled on a demonstrated interaction between BLM and p53 both from African green monkey.BIND15806145 
-HPRD,BioGRID11781842 
p53 interacts with BLM.BIND11781842 
BLMCHAF1AAffinity Capture-Western; Far Western; Two-hybridBioGRID15143166 
BLMWRNBLM interacts with WRN.BIND11919194 
-HPRD,BioGRID11919194 
BLMTP53BLM interacts with p53.BIND12080066 
BLM interacts with p53. This interaction was modeled on a demonstrated interaction between BLM and p53 both from African green monkey.BIND15806145 
-HPRD,BioGRID11781842 
p53 interacts with BLM.BIND11781842 
BLMWRNBLM interacts with WRN.BIND11919194 
-HPRD,BioGRID11919194 
BLMMSH2Co-purificationBioGRID10783165 
BLMMSH6Co-purificationBioGRID10783165 
BLMMLH1-HPRD,BioGRID11691925 
MLH1 interacts with BLM.BIND11691925 
BLMTP53BLM interacts with p53.BIND12080066 
BLM interacts with p53. This interaction was modeled on a demonstrated interaction between BLM and p53 both from African green monkey.BIND15806145 
-HPRD,BioGRID11781842 
p53 interacts with BLM.BIND11781842 
BLMMLH1-HPRD,BioGRID11691925 
MLH1 interacts with BLM.BIND11691925 
BLMTP53BLM interacts with p53.BIND12080066 
BLM interacts with p53. This interaction was modeled on a demonstrated interaction between BLM and p53 both from African green monkey.BIND15806145 
-HPRD,BioGRID11781842 
p53 interacts with BLM.BIND11781842 
BLMFANCD2Affinity Capture-WesternBioGRID15257300 
BLMCHEK1Affinity Capture-Western; Co-localizationBioGRID15364958 
BLMTERF2-HPRD,BioGRID12181313 
BLM interacts with TRF2.BIND12181313 
BLMTOP3ABLM interacts with Top3A (Topo III-alpha).BIND15775963 
-HPRD10734115 |11406610 
BLM interacts with Topoisomerase III-alpha.BIND10734115 
Affinity Capture-Western; Co-localization; Far Western; Reconstituted ComplexBioGRID10734115 |10825162 
|11406610 |11470874 
|15143166 
BLMTOP3ABLM interacts with Top3A (Topo III-alpha).BIND15775963 
-HPRD10734115 |11406610 
BLM interacts with Topoisomerase III-alpha.BIND10734115 
Affinity Capture-Western; Co-localization; Far Western; Reconstituted ComplexBioGRID10734115 |10825162 
|11406610 |11470874 
|15143166 
BLMFANCAAffinity Capture-MSBioGRID12973351 
BLMTOP3ABLM interacts with Top3A (Topo III-alpha).BIND15775963 
-HPRD10734115 |11406610 
BLM interacts with Topoisomerase III-alpha.BIND10734115 
Affinity Capture-Western; Co-localization; Far Western; Reconstituted ComplexBioGRID10734115 |10825162 
|11406610 |11470874 
|15143166 
BLMMRE11ACo-purificationBioGRID10783165 
BLMXRCC2Affinity Capture-Western; Reconstituted ComplexBioGRID12975363 
BLMTERF2-HPRD,BioGRID12181313 
BLM interacts with TRF2.BIND12181313 
BLMMX1-HPRD,BioGRID11716541 
BLMSMC1A-HPRD11877377 
BLMRPA1Biochemical Activity; Co-localization; Reconstituted ComplexBioGRID10825162 |11950880 
|12181313 
BLMTOP3ABLM interacts with Top3A (Topo III-alpha).BIND15775963 
-HPRD10734115 |11406610 
BLM interacts with Topoisomerase III-alpha.BIND10734115 
Affinity Capture-Western; Co-localization; Far Western; Reconstituted ComplexBioGRID10734115 |10825162 
|11406610 |11470874 
|15143166 
BLMRAD51L3-HPRD,BioGRID12975363 
BLMFEN1Affinity Capture-Western; Reconstituted ComplexBioGRID14688284 
BLMRFC1Co-purificationBioGRID10783165 
ATMCHEK1Protein-peptideBioGRID10608806 
ATMATRProtein-peptideBioGRID10608806 
ATMBRCA2Reconstituted ComplexBioGRID15199141 
ATMTP53-HPRD,BioGRID9843217 
ATM phosphorylates p53 at serine 15.BIND15064416 
An unspecified isoform of ATM interacts with and phosphorylates p53. This interaction was modeled on a demonstrated interaction between human ATM and p53 from an unspecified species.BIND15916964 
ATM phosphorylates p53 at Ser15.BIND15175154 
ATM phosphorylates p53 at serine 15.BIND15790808 
ATMHINT1-HPRD7644499 
ATMTP53-HPRD,BioGRID9843217 
ATM phosphorylates p53 at serine 15.BIND15064416 
An unspecified isoform of ATM interacts with and phosphorylates p53. This interaction was modeled on a demonstrated interaction between human ATM and p53 from an unspecified species.BIND15916964 
ATM phosphorylates p53 at Ser15.BIND15175154 
ATM phosphorylates p53 at serine 15.BIND15790808 
ATMTERF1-HPRD,BioGRID11375976 
ATMTP53-HPRD,BioGRID9843217 
ATM phosphorylates p53 at serine 15.BIND15064416 
An unspecified isoform of ATM interacts with and phosphorylates p53. This interaction was modeled on a demonstrated interaction between human ATM and p53 from an unspecified species.BIND15916964 
ATM phosphorylates p53 at Ser15.BIND15175154 
ATM phosphorylates p53 at serine 15.BIND15790808 
ATMTP53-HPRD,BioGRID9843217 
ATM phosphorylates p53 at serine 15.BIND15064416 
An unspecified isoform of ATM interacts with and phosphorylates p53. This interaction was modeled on a demonstrated interaction between human ATM and p53 from an unspecified species.BIND15916964 
ATM phosphorylates p53 at Ser15.BIND15175154 
ATM phosphorylates p53 at serine 15.BIND15790808 
ATMTP53-HPRD,BioGRID9843217 
ATM phosphorylates p53 at serine 15.BIND15064416 
An unspecified isoform of ATM interacts with and phosphorylates p53. This interaction was modeled on a demonstrated interaction between human ATM and p53 from an unspecified species.BIND15916964 
ATM phosphorylates p53 at Ser15.BIND15175154 
ATM phosphorylates p53 at serine 15.BIND15790808 
ATMRHEBAffinity Capture-Western; Reconstituted ComplexBioGRID15854902 
ATM interacts with Rheb.BIND15854902 
ATMPRKDC-HPRD,BioGRID10464290 
ATMAP2A2Protein-peptideBioGRID10608806 
ATMCHEK2ATM phosphorylates Chk2 at threonine 68.BIND15790808 
ATM phosphorylates Chk2 at threonine 68.BIND15064416 
ATMMSH6Co-purificationBioGRID10783165 
ATMMLH1Co-purificationBioGRID10783165 
ATMPTSProtein-peptideBioGRID10608806 
ATMTIPARP-HPRD11238919 
ATMXRCC5XRCC5 (Ku80) interacts with ATM.BIND15758953 
ATMMSH2Co-purificationBioGRID10783165 
ATMEIF4EBP1Protein-peptideBioGRID10608806 
ATMLIG4Protein-peptideBioGRID10608806 
ATMAP1B1Protein-peptideBioGRID10608806 
ATMRAD17-HPRD,BioGRID11418864 
ATMUPF1ATM phosphorylates hUpf1.BIND15175154 
ATMMRE11AATM interacts with MRE11A (Mre11).BIND15758953 
Co-purification; Protein-peptideBioGRID10608806 |10783165 
ATMABL1-HPRD,BioGRID9168117 
ATMEEF1E1p18 interacts with ATM.BIND15680327 
ATMRHEBAffinity Capture-Western; Reconstituted ComplexBioGRID15854902 
ATM interacts with Rheb.BIND15854902 
ATMRFC1Co-purificationBioGRID10783165 
ATMMRE11AATM interacts with MRE11A (Mre11).BIND15758953 
Co-purification; Protein-peptideBioGRID10608806 |10783165 
ATMCAT-HPRD10567403 
ATMCREB1Affinity Capture-WesternBioGRID15073328 
ATMAP3B2-HPRD9707615 
ATME4F1Protein-peptideBioGRID10608806 
ATMAP2B1-HPRD9707615 
ATMWRNProtein-peptideBioGRID10608806 
ATMATF2An unspecified isoform of ATM interacts with and phosphorylates ATF2.BIND15916964 
ATMRBBP8Affinity Capture-Western; Protein-peptide; Reconstituted ComplexBioGRID10608806 |10910365 
ATMCHEK2ATM phosphorylates Chk2 at threonine 68.BIND15790808 
ATM phosphorylates Chk2 at threonine 68.BIND15064416 
ATMPEX5-HPRD,BioGRID10567403 
ATMSMC1AAffinity Capture-Western; Reconstituted ComplexBioGRID11877376 
ATMMCM2Biochemical ActivityBioGRID15210935 
ATMFANCD2Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID12086603 |14499622 


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.