Protein-protein interaction for HOXC8

EMBED not supported by browser.
Nodes, degree=1 Nodes, degree=2


Protein-protein interaction data for gene HOXC8

Degree = 1
Interactor A Interactor B Experimental method Source Pubmed
HOXC8MSX1Reconstituted ComplexBioGRID9111364 
HOXC8SMAD4-HPRD,BioGRID10224145 
HOXC8BTG2-HPRD,BioGRID10617598 
HOXC8SMAD6-HPRD,BioGRID10722652 
HOXC8SMAD1-HPRD,BioGRID10224145 |11139569 
HOXC8MLLMLL1 interacts with HOXC8 promoter.BIND15960974 
MLL1 interacts with HOXC8.BIND15960974 
HOXC8HOMEZ-HPRD12925734 
HOXC8BMPR1A-HPRD11139569 
HOXC8DLX2Reconstituted ComplexBioGRID9111364 
HOXC8DLX5Reconstituted ComplexBioGRID9111364 

Degree = 2
Interactor A Interactor B Experimental method Source Pubmed
MSX1MSX2-HPRD,BioGRID9111364 
MSX1LHX2-HPRD,BioGRID9697309 
MSX1TBPAffinity Capture-Western; in vivo; Phenotypic Suppression; Reconstituted ComplexBioGRID8700832 |9111364 
|10215616 
-HPRD8700832 |10215616 
MSX1CREBBP-HPRD,BioGRID10215616 |11115394 
MSX1RGS7-HPRD10862767 
MSX1SP1-HPRD,BioGRID10215616 
MSX1PAX3Reconstituted ComplexBioGRID10529415 
MSX1TP53MSX1 interacts with TP53 (p53). This interaction was modeled on a demonstrated interaction between MSX1 from an unspecified species, and human p53.BIND15705871 
MSX1TAF1-HPRD,BioGRID8700832 
MSX1TBPAffinity Capture-Western; in vivo; Phenotypic Suppression; Reconstituted ComplexBioGRID8700832 |9111364 
|10215616 
-HPRD8700832 |10215616 
SMAD4SPTBN1-HPRD12543979 
SMAD4GLI3-HPRD9843199 
SMAD4HOXA9-HPRD,BioGRID11042172 
SMAD4ATF2-HPRD,BioGRID10085140 
SMAD4ZNF423-HPRD,BioGRID10660046 
SMAD4SMAD3-HPRD9311995|9732876 
Smad3 interacts with Smad4. This interaction was modeled on a demonstrated interaction between Smad3 from an unspecified species and Smad4 from an unspecified species.BIND9311995 
Smad4 interacts with Smad3.BIND15761153 
Affinity Capture-WesternBioGRID9311995 |9892009 
|10531362 |11114293 
|12419246 |12794086 
|15084259 
SMAD4UBE2ITwo-hybridBioGRID16189514 
SMAD4STK11IP-HPRD,BioGRID11741830 
SMAD4DVL1Reconstituted ComplexBioGRID12650946 
SMAD4MDM4Reconstituted ComplexBioGRID12483531 
SMAD4MEF2A-HPRD11160896 
SMAD4EID2-HPRD,BioGRID14612439 
SMAD4AKT1Affinity Capture-WesternBioGRID16362038 
SMAD4FOXO3-HPRD,BioGRID15084259 
FoxO3 interacts with Smad4.BIND15084259 
SMAD4CITED1-HPRD,BioGRID9707553 
SMAD4MED15-HPRD12167862 
SMAD4DCP1A-HPRD,BioGRID11836524 
SMAD4EP300Affinity Capture-WesternBioGRID10887155 
p300 interacts with Smad4 fragment. p300 interacting with full-length Smad4 could not be demonstrated in vitro. This interaction was modeled on a demonstrated interaction between p300 from an unspecified species and human Smad4 fragment.BIND9679056 
SMAD4SMAD7Phenotypic SuppressionBioGRID9892009 
SMAD4SMAD3-HPRD9311995|9732876 
Smad3 interacts with Smad4. This interaction was modeled on a demonstrated interaction between Smad3 from an unspecified species and Smad4 from an unspecified species.BIND9311995 
Smad4 interacts with Smad3.BIND15761153 
Affinity Capture-WesternBioGRID9311995 |9892009 
|10531362 |11114293 
|12419246 |12794086 
|15084259 
SMAD4RBL1-HPRD,BioGRID12150994 
SMAD4ACVR1B-HPRD9892009 
SMAD4SKILSmad4 interacts with SnoN. This interaction was modeled on a demonstrated interaction between human Smad4 and SnoN from an unspecified species.BIND15761153 
-HPRD,BioGRID10531062 
SMAD4JUND-HPRD10220381 
SMAD4CEBPBCEBPB (C/EBP-beta) interacts with SMAD4. This interaction was modeled on a demonstrated interaction between CEBPB and SMAD4, both from unspecified species.BIND12202226 
-HPRD,BioGRID12524424 
SMAD4EWSR1Two-hybridBioGRID16189514 
SMAD4PIAS3-HPRD,BioGRID14691252 
SMAD4SMAD9Affinity Capture-Western; Two-hybridBioGRID10583507 |16189514 
SMAD4PARD3BReconstituted ComplexBioGRID12650946 
SMAD4DLX1-HPRD,BioGRID14671321 
SMAD4TGFBR2T-beta-RII phosphorylates hMAD-4. This interaction was modeled on a demonstrated interaction between T-beta-RII from an unspecified species and human hMAD-4.BIND8774881 
SMAD4FOXO3-HPRD,BioGRID15084259 
FoxO3 interacts with Smad4.BIND15084259 
SMAD4SNW1Phenotypic Enhancement; Two-hybridBioGRID11278756 
SMAD4SKI-HPRD,BioGRID12419246 |12857746 
Smad4 interacts with Ski. This interaction was modeled on a demonstrated interaction between human Smad4 and Ski from an unspecified species.BIND15761153 
c-Ski interacts with Smad4. This interaction was modelled on a demonstrated interaction between Smad4 from an unspecified source and human c-Ski.BIND10575014 
SMAD4SMAD3-HPRD9311995|9732876 
Smad3 interacts with Smad4. This interaction was modeled on a demonstrated interaction between Smad3 from an unspecified species and Smad4 from an unspecified species.BIND9311995 
Smad4 interacts with Smad3.BIND15761153 
Affinity Capture-WesternBioGRID9311995 |9892009 
|10531362 |11114293 
|12419246 |12794086 
|15084259 
SMAD4SUMO1SMAD4 is sumoylated.BIND15592428 
SMAD4SP1-HPRD11432852 
SMAD4MAX-HPRD,BioGRID12551947 
SMAD4EP300Affinity Capture-WesternBioGRID10887155 
p300 interacts with Smad4 fragment. p300 interacting with full-length Smad4 could not be demonstrated in vitro. This interaction was modeled on a demonstrated interaction between p300 from an unspecified species and human Smad4 fragment.BIND9679056 
SMAD4SMAD2-HPRD,BioGRID11274206 
Smad4 interacts with Smad2.BIND15761153 
Smad2 interacts with Smad4. This interaction was modeled on a demonstrated interaction between Smad2 from an unspecified species and Smad4 from an unspecified species.BIND9311995 
SMAD4JUN-HPRD10220381 
SMAD4SNIP1-HPRD,BioGRID10887155 
SMAD4FOXO4-HPRD,BioGRID15084259 
FoxO4 interacts with Smad4.BIND15084259 
SMAD4JUNB-HPRD,BioGRID10220381 
SMAD4BTRC-HPRD,BioGRID14988407 
SMAD4SMAD5Affinity Capture-WesternBioGRID10531362 
SMAD4SMAD3-HPRD9311995|9732876 
Smad3 interacts with Smad4. This interaction was modeled on a demonstrated interaction between Smad3 from an unspecified species and Smad4 from an unspecified species.BIND9311995 
Smad4 interacts with Smad3.BIND15761153 
Affinity Capture-WesternBioGRID9311995 |9892009 
|10531362 |11114293 
|12419246 |12794086 
|15084259 
SMAD4TGFBR1T-beta-RI phosphorylates hMAD-4. This interaction was modeled on a demonstrated interaction between T-beta-RI from an unspecified species and human hMAD-4.BIND8774881 
Co-fractionationBioGRID11102446 
SMAD4CAMK2G-HPRD,BioGRID11027280 
SMAD4TGFBR1T-beta-RI phosphorylates hMAD-4. This interaction was modeled on a demonstrated interaction between T-beta-RI from an unspecified species and human hMAD-4.BIND8774881 
Co-fractionationBioGRID11102446 
SMAD4STUB1Smad4 interacts with CHIP. This interaction was modeled on a demonstrated interaction between Smad1 and CHIP, both from an unspecified species.BIND15708501 
SMAD4SKI-HPRD,BioGRID12419246 |12857746 
Smad4 interacts with Ski. This interaction was modeled on a demonstrated interaction between human Smad4 and Ski from an unspecified species.BIND15761153 
c-Ski interacts with Smad4. This interaction was modelled on a demonstrated interaction between Smad4 from an unspecified source and human c-Ski.BIND10575014 
SMAD4KPNB1Affinity Capture-WesternBioGRID10846168 
SMAD4CTNNB1-HPRD,BioGRID12000714 
SMAD4CEBPDAffinity Capture-Western; Reconstituted ComplexBioGRID12524424 
SMAD4SMAD2-HPRD,BioGRID11274206 
Smad4 interacts with Smad2.BIND15761153 
Smad2 interacts with Smad4. This interaction was modeled on a demonstrated interaction between Smad2 from an unspecified species and Smad4 from an unspecified species.BIND9311995 
SMAD4FOXO4-HPRD,BioGRID15084259 
FoxO4 interacts with Smad4.BIND15084259 
SMAD4FOXO1FoxO1 interacts with Smad4.BIND15084259 
-HPRD,BioGRID15084259 
SMAD4CEBPBCEBPB (C/EBP-beta) interacts with SMAD4. This interaction was modeled on a demonstrated interaction between CEBPB and SMAD4, both from unspecified species.BIND12202226 
-HPRD,BioGRID12524424 
SMAD4PIAS4Affinity Capture-WesternBioGRID12815042 
SMAD4TSSK3SMAD4 interacts with STK22C. This interaction was modeled on a demonstrated interaction between human SMAD4 and mouse STK22C.BIND15761153 
SMAD4TFE3-HPRD,BioGRID10557285 
SMAD4DACH1-HPRD14525983 
SMAD4TOB1-HPRD,BioGRID11163184 
SMAD4LEF1-HPRD,BioGRID10890911 
SMAD4TGFBRAP1-HPRD,BioGRID11278302 
SMAD4SMAD2-HPRD,BioGRID11274206 
Smad4 interacts with Smad2.BIND15761153 
Smad2 interacts with Smad4. This interaction was modeled on a demonstrated interaction between Smad2 from an unspecified species and Smad4 from an unspecified species.BIND9311995 
SMAD4SKI-HPRD,BioGRID12419246 |12857746 
Smad4 interacts with Ski. This interaction was modeled on a demonstrated interaction between human Smad4 and Ski from an unspecified species.BIND15761153 
c-Ski interacts with Smad4. This interaction was modelled on a demonstrated interaction between Smad4 from an unspecified source and human c-Ski.BIND10575014 
SMAD4TGFB1I1ARA55 interacts with Smad4. This interaction was modeled on a demonstrated interaction between human ARA55 and Smad4 from an unspecified species.BIND15561701 
SMAD4ECSIT-HPRD14633973 
SMAD4BRCA1BRCA1 interacts with Smad4. This interaction was modeled on a demonstrated interaction between BRCA1 from human and Smad4 from an unspecified species.BIND15735739 
SMAD4ZNF521-HPRD14630787 
SMAD4AR-HPRD,BioGRID12226080 
SMAD4FOXO1FoxO1 interacts with Smad4.BIND15084259 
-HPRD,BioGRID15084259 
SMAD4FSTL3-HPRD11571638 
SMAD4COPS5-HPRD,BioGRID11818334 
SMAD4ZNF8-HPRD12370310 
SMAD4SKILSmad4 interacts with SnoN. This interaction was modeled on a demonstrated interaction between human Smad4 and SnoN from an unspecified species.BIND15761153 
-HPRD,BioGRID10531062 
SMAD4TRIM33Smad4 interacts with Ecto.BIND15820681 
SMAD4UBE2L3-HPRD12794086 
SMAD4CDKN1ASmad4 binds the distal region of the p21Cip1 promoter.BIND15084259 
SMAD4FOXH1Reconstituted Complex; Two-hybridBioGRID9288972 
SMAD4ERBB2IP-HPRD,BioGRID12650946 
SMAD4CEBPAReconstituted ComplexBioGRID12524424 
BTG2PICK1-HPRD11237868 
BTG2CNOT8-HPRD,BioGRID11136725 
BTG2CNOT7Reconstituted ComplexBioGRID11136725 
-HPRD9712883 
BTG2HOXB9-HPRD,BioGRID10617598 
BTG2CNOT7Reconstituted ComplexBioGRID11136725 
-HPRD9712883 
BTG2PRMT1-HPRD,BioGRID11856371 
-HPRD8663146 |11856371|11856371 
BTG2CNOT6LAffinity Capture-MSBioGRID17353931 
BTG2PRMT1-HPRD,BioGRID11856371 
-HPRD8663146 |11856371|11856371 
BTG2PKCBiochemical ActivityBioGRID11237868 
BTG2CNOT1Affinity Capture-MSBioGRID17353931 
SMAD6MAP3K7-HPRD,BioGRID10748100 
SMAD6STAMBP-HPRD,BioGRID11483516 
SMAD6RNF111-HPRD,BioGRID14657019 
SMAD6SMURF1-HPRD,BioGRID11278251 
SMAD6PIAS4Affinity Capture-Western; Two-hybridBioGRID12815042 
SMAD6STRAP-HPRD,BioGRID10757800 
SMAD6SMAD7-HPRD,BioGRID9256479 
SMAD6MAP3K7IP1-HPRD,BioGRID11737269 
SMAD6CTBP1Affinity Capture-WesternBioGRID14645520 
SMAD1LEF1-HPRD,BioGRID10890911 
SMAD1CREBBPAffinity Capture-WesternBioGRID10673036 |11239394 
SMAD1HIPK2-HPRD,BioGRID12874272 
SMAD1RUNX2Affinity Capture-WesternBioGRID10531362 |10962029 
SMAD1FOXG1-HPRD,BioGRID11387330 
SMAD1PSMB4-HPRD,BioGRID12097147 
SMAD1SNX6-HPRD11279102 
SMAD1LEMD3LEMD3 interacts with Smad1. This interaction was modelled on a demonstrated interaction between human LEMD3 and mouse Smad1.BIND15489854 
SMAD1EP300-HPRD,BioGRID10673036 
SMAD1SNIP1-HPRD,BioGRID10887155 
SMAD1ZEB2-HPRD10400677 
SMAD1ZNF8-HPRD12370310 
SMAD1STUB1Smad1 interacts with CHIP. This interaction was modeled on a demonstrated interaction between Smad1 and CHIP, both from an unspecified species.BIND15708501 
SMAD1BMP7Phenotypic SuppressionBioGRID11438941 
SMAD1RPS27ATwo-hybridBioGRID11438941 
SMAD1ZEB1Affinity Capture-WesternBioGRID12743038 
SMAD1XPO1-HPRD12519765 
SMAD1TOB1-HPRD,BioGRID11163184 
SMAD1SKILSmad1 interacts with SnoN. This interaction was modeled on a demonstrated interaction between SnoN from an unspecified source and human Smad1.BIND12426322 
SMAD1SKIAffinity Capture-Western; Reconstituted ComplexBioGRID12874272 
SMAD1RUNX1Affinity Capture-WesternBioGRID10531362 
SMAD1STAT3Affinity Capture-WesternBioGRID10205054 
SMAD1OAZ3Two-hybridBioGRID11438941 
SMAD1ZNF423-HPRD,BioGRID10660046 
SMAD1GDF6-HPRD15246821 
SMAD1TGIF1Affinity Capture-WesternBioGRID10199400 
SMAD1NEDD9-HPRD,BioGRID11118211 
SMAD1ACVR1-HPRD9748228 |10583507 
|10652350 
Affinity Capture-WesternBioGRID9748228 |10652350 
SMAD1DVL1Reconstituted ComplexBioGRID12650946 
SMAD1SMURF2SMAD1 interacts with SMURF2.BIND15761153 
-HPRD,BioGRID11016919 
SMAD1RANSMAD1 interacts with RAN. This interaction was modeled on a demonstrated interaction between human SMAD1 and mouse RAN.BIND15761153 
SMAD1ECSIT-HPRD14633973 
SMAD1PARD3BReconstituted ComplexBioGRID12650946 
SMAD1GLI3-HPRD9843199 
SMAD1ACVR1-HPRD9748228 |10583507 
|10652350 
Affinity Capture-WesternBioGRID9748228 |10652350 
SMAD1RUNX3Affinity Capture-WesternBioGRID10531362 
SMAD1ZNF521-HPRD14630787 
SMAD1UBA52Two-hybridBioGRID11438941 
SMAD1ERBB2IP-HPRD,BioGRID12650946 
SMAD1NEUROG1-HPRD,BioGRID11239394 
SMAD1SMURF2SMAD1 interacts with SMURF2.BIND15761153 
-HPRD,BioGRID11016919 
MLLPPIE-HPRD,BioGRID11313484 
MLLTAF9-HPRD10821850 
MLLINSBiochemical ActivityBioGRID14607844 
MLLAVPBiochemical ActivityBioGRID14607844 
MLLHDAC1Affinity Capture-Western; Reconstituted ComplexBioGRID12829790 
MLLHOXA9MLL1 interacts with HOXA9 promoter.BIND15960974 
MLL1 interacts with HOXA9.BIND15960974 
MLLSMARCB1Affinity Capture-WesternBioGRID10490642 
MLLWDR5WDR5 interacts with MLL. This interaction was modeled on a demonstrated interaction between WDR5 from an unspecified species and human MLL.BIND15960975 
Affinity Capture-Western; Co-purificationBioGRID15199122 
MLLRBBP5RbBP5 interacts with MLL.BIND15960975 
Affinity Capture-Western; Co-purificationBioGRID15199122 
MLLASH2LAffinity Capture-Western; Co-purificationBioGRID15199122 
MLLPPP1R15A-HPRD,BioGRID10490642 
MLLRNF2Ring2 interacts with MLL.BIND15960975 
MLLCTBP1Affinity Capture-Western; Reconstituted ComplexBioGRID12829790 
MLLRBBP5RbBP5 interacts with MLL.BIND15960975 
Affinity Capture-Western; Co-purificationBioGRID15199122 
MLLBMI1-HPRD,BioGRID12829790 
MLLHCFC1Affinity Capture-Western; Co-purificationBioGRID15199122 
MLLMEN1Affinity Capture-Western; Co-purificationBioGRID15199122 
MLLMYST1MOF interacts with MLL.BIND15960975 
MLLWDR5WDR5 interacts with MLL. This interaction was modeled on a demonstrated interaction between WDR5 from an unspecified species and human MLL.BIND15960975 
Affinity Capture-Western; Co-purificationBioGRID15199122 
MLLCBX4Reconstituted ComplexBioGRID12829790 
MLLFASLG-HPRD12023017 
MLLCREBBP-HPRD,BioGRID11259575 |12205094 
MLLOXTBiochemical ActivityBioGRID14607844 
MLLMAP3K5Affinity Capture-WesternBioGRID14607843 
MLLPLXNB1-HPRD12123608 
MLLHCFC2Affinity Capture-Western; Co-purificationBioGRID15199122 
MLLHOXA9MLL1 interacts with HOXA9 promoter.BIND15960974 
MLL1 interacts with HOXA9.BIND15960974 
BMPR1ABMP7Reconstituted ComplexBioGRID8006002 
-HPRD7791754 |8605097 
BMPR1ASF3B4-HPRD,BioGRID15351706 
BMPR1ABMP6-HPRD,BioGRID10504300 |11401330 
BMPR1ATGFBRAP1-HPRD11278302 
BMPR1ABMP7Reconstituted ComplexBioGRID8006002 
-HPRD7791754 |8605097 
BMPR1ABMPR1B-HPRD,BioGRID10712517 
BMPR1AFKBP1ATwo-hybridBioGRID9663660 
BMPR1AGDF9-HPRD10712517 |12135884 
BMPR1ABMP2Co-crystal Structure; Reconstituted ComplexBioGRID10692589 |10712517 
|10880444 |11263668 
-HPRD10692589 |10881198 
|11263668|11263668 
BMPR1ABMP4-HPRD8702914 |11241215 
Reconstituted ComplexBioGRID8006002 
BMPR1ABMP2Co-crystal Structure; Reconstituted ComplexBioGRID10692589 |10712517 
|10880444 |11263668 
-HPRD10692589 |10881198 
|11263668|11263668 
BMPR1ABMP4-HPRD8702914 |11241215 
Reconstituted ComplexBioGRID8006002 
BMPR1ABMPR2-HPRD,BioGRID10712517 
BMPR1AGDF6Reconstituted ComplexBioGRID9525338 
BMPR1AGDF5-HPRD,BioGRID9525338 |11282024 
BMPR1AMAP3K7IP1-HPRD9663660 
BMPR1AFKBP1BTwo-hybridBioGRID15351706 
BMPR1ASMAD7Affinity Capture-WesternBioGRID15148321 
BMPR1AZMYND11Affinity Capture-Western; Two-hybridBioGRID9663660 
DLX2MSX2-HPRD,BioGRID9111364 
DLX2XRCC6Reconstituted ComplexBioGRID11279128 
DLX2DIP2A-HPRD11675124 
DLX5MSX2-HPRD,BioGRID9111364 
DLX5MAGED1in vivo; Two-hybridBioGRID11084035 
DLX5SPEN-HPRD10451362 


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.