Protein-protein interaction for IRAK1

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Protein-protein interaction data for gene IRAK1

Degree = 1
Interactor A Interactor B Experimental method Source Pubmed
IRAK1MYD88IRAK does not interact with MyD88, whilst the kinase inactive mutant IRAK[Lys239Ser] does interact.BIND10383454 
-HPRD10854325 
Affinity Capture-WesternBioGRID10383454 |11976320 
IRAK does not interact with MyD88, whilst the kinase inactive mutant IRAK[Lys239Ser] does interact.BIND10383454 
-HPRD10854325 
Affinity Capture-WesternBioGRID10383454 |11976320 
IRAK1TRAF6TRAF6 interacts with IRAK1. This interaction was modeled on a demonstrated interaction between TRAF6 and IRAK1, both from unspecified species.BIND15894263 
-HPRD,BioGRID8837778 
TRAF6 interacts with IRAK1. This interaction was modeled on a demonstrated interaction between TRAF6 and IRAK1, both from unspecified species.BIND15894263 
-HPRD,BioGRID8837778 
IRAK1TIFA-HPRD,BioGRID12566447 
-HPRD,BioGRID12566447 
IRAK1IL1RAP-HPRD,BioGRID9371760 
-HPRD,BioGRID9371760 
IRAK1PRKCZ-HPRD,BioGRID11937546 
-HPRD,BioGRID11937546 
IRAK1IRAK1IRAK interacts with itself and also autophosphorylates.BIND10383454 
IRAK interacts with itself and also autophosphorylates.BIND10383454 
IRAK1IRAK1BP1-HPRD,BioGRID11096118 
-HPRD,BioGRID11096118 
IRAK1PELI3-HPRD12874243 
-HPRD12874243 
IRAK1AKT1-HPRD,BioGRID11976320 
-HPRD,BioGRID11976320 
IRAK1IKBKBAffinity Capture-WesternBioGRID11096118 
Affinity Capture-WesternBioGRID11096118 
IRAK1FADD-HPRD,BioGRID11828002 
-HPRD,BioGRID11828002 
IRAK1ITGAM-HPRD,BioGRID11701612 
-HPRD,BioGRID11701612 
IRAK1TOLLIP-HPRD,BioGRID10854325 
-HPRD,BioGRID10854325 
IRAK1SQSTM1-HPRD12034707 
Affinity Capture-WesternBioGRID10747026 
-HPRD12034707 
Affinity Capture-WesternBioGRID10747026 
IRAK1HRAS-HPRD11744690 
-HPRD11744690 
IRAK1TICAM2-HPRD12721283 
-HPRD12721283 
IRAK1TLR2-HPRD,BioGRID10395652 
-HPRD,BioGRID10395652 
IRAK1IRAK3IRAK interacts with IRAK-M and forms a heterocomplex.BIND10383454 
IRAK interacts with IRAK-M and forms a heterocomplex.BIND10383454 
IRAK1IRAK4-HPRD,BioGRID11960013 
-HPRD,BioGRID11960013 
IRAK1PELI2-HPRD12370331 
IRAK1 interacts with and phosphorylates PELI2.BIND12860405 
-HPRD12370331 
IRAK1 interacts with and phosphorylates PELI2.BIND12860405 
IRAK1NTRK3-HPRD12034707 
-HPRD12034707 
IRAK1IRAK2IRAK interacts with IRAK-2 and forms a heterocomplex.BIND10383454 
IRAK interacts with IRAK-2 and forms a heterocomplex.BIND10383454 
IRAK1CHUKAffinity Capture-WesternBioGRID11096118 
Affinity Capture-WesternBioGRID11096118 
IRAK1MAP3K7IP2-HPRD11518704 
-HPRD11518704 
IRAK1SIGIRR-HPRD,BioGRID12925853 
-HPRD,BioGRID12925853 

Degree = 2
Interactor A Interactor B Experimental method Source Pubmed
MYD88IRF7IRF7 interacts with MyD88.BIND15361868 
MYD88SPOPTwo-hybridBioGRID16189514 
MYD88TLR3-HPRD,BioGRID12646618 
MYD88RAC1Affinity Capture-Western; Reconstituted ComplexBioGRID11416133 
MYD88TLR4Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID10952994 |12646618 
|15107846 
-HPRD10952994 |11743586 
MYD88IL1R1Affinity Capture-WesternBioGRID10854325 
MYD88TLR5Two-hybridBioGRID15107846 
MYD88TLR4Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID10952994 |12646618 
|15107846 
-HPRD10952994 |11743586 
MYD88TIRAP-HPRD,BioGRID11544529 
MYD88TLR9Two-hybridBioGRID15107846 
TRAF6MTHFD1Affinity Capture-MSBioGRID17353931 
TRAF6EPPK1Affinity Capture-MSBioGRID17353931 
TRAF6UBBTRAF6 interacts with Ub. This interaction was modeled on a demonstrated interaction between TRAF6 from mouse and Ub from an unspecified source.BIND15125833 
TRAF6IRF7IRF7 intereacts with TRAF6. This interaction was modeled on a demonstrated interaction between mouse IRF7 and human TRAF6.BIND15361868 
TRAF6MAP3K7IP3TAB3 interacts with TRAF6.BIND15327770 
-HPRD,BioGRID14633987 
TRAF6MALT1TRAF6 interacts with MALT1. This interaction was modeled on a demonstrated interaction between TRAF6 from mouse and MALT1 from human.BIND15125833 
TRAF6TMEM189-UBE2V1-HPRD,BioGRID11057907 
TRAF6PSMC2Affinity Capture-MSBioGRID14743216 
TRAF6ECSIT-HPRD,BioGRID10465784 
TRAF6MAP3K7-HPRD,BioGRID10094049 
TRAF6PSMD8-HPRD14743216 
TRAF6KCNQ1Affinity Capture-MSBioGRID14743216 
TRAF6ZFAND5Affinity Capture-WesternBioGRID14754897 
ZNF216 interacts with TRAF6. This interaction was modeled on a demonstrated interaction between human ZNF216 and TRAF6 from an unspecified species.BIND14754897 
TRAF6TICAM1TRIF interacts with TRAF6.BIND14530355 
An unspecified isoform of TRIF interacts with TRAF6. This interaction was modeled on a demonstrated interaction between TRIF from an unspecified species and TRAF from an unspecified species.BIND15474016 
TRAF6TNFRSF11AAffinity Capture-Western; Reconstituted ComplexBioGRID9685412 |9852070 
|10025951 |10075662 
|11809792 
-HPRD9685412 |10025951 
|10075662 |10635328 
TRAF6MCM7Affinity Capture-MSBioGRID17353931 
TRAF6NASPAffinity Capture-MSBioGRID17353931 
TRAF6IARSAffinity Capture-MSBioGRID17353931 
TRAF6PSMB5Affinity Capture-MSBioGRID14743216 
TRAF6MAP3K7IP3TAB3 interacts with TRAF6.BIND15327770 
-HPRD,BioGRID14633987 
TRAF6TNFRSF13B-HPRD,BioGRID10880535 
TRAF6TAX1BP1-HPRD,BioGRID10920205 
TRAF6CD40Reconstituted ComplexBioGRID9384571 |9990007 
-HPRD10075662 |10411888 
TRAF6CD40Reconstituted ComplexBioGRID9384571 |9990007 
-HPRD10075662 |10411888 
TRAF6EIF4E2Affinity Capture-MSBioGRID17353931 
TRAF6TRIM37-HPRD,BioGRID11279055 
TRAF6TTRAP-HPRD,BioGRID10764746 
TRAF6PSMD3-HPRD,BioGRID14743216 
TRAF6MAP3K14-HPRD,BioGRID11278268 
NIK interacts with TRAF6. This interaction was modeled on a demonstrated interaction between human NIK and TRAF6 from an unspecified species.BIND9275204 
TRAF6OTUD7B-HPRD,BioGRID11463333 
-HPRD9928991 
TRAF6MAP3K5-HPRD,BioGRID10523862 
TRAF6ATP2A2-HPRD14743216 
TRAF6PSMD7Affinity Capture-MSBioGRID14743216 
TRAF6ZRANB1-HPRD,BioGRID11463333 
TRAF6EDA2R-HPRD,BioGRID12060722 
TRAF6PSMC1Affinity Capture-MSBioGRID14743216 
TRAF6VDAC1Affinity Capture-MSBioGRID17353931 
TRAF6PSMD4-HPRD14743216 
TRAF6ZNF675-HPRD,BioGRID11751921 
TRAF6USP7-HPRD,BioGRID11279055 
TRAF6TRAF2Two-hybridBioGRID16189514 
TRAF6XIAP-HPRD,BioGRID12048196 
TRAF6NGFR-HPRD,BioGRID10514511 
TRAF6ZFAND5Affinity Capture-WesternBioGRID14754897 
ZNF216 interacts with TRAF6. This interaction was modeled on a demonstrated interaction between human ZNF216 and TRAF6 from an unspecified species.BIND14754897 
TRAF6OTUD7B-HPRD,BioGRID11463333 
-HPRD9928991 
TRAF6SPOP-HPRD,BioGRID11279055 
TRAF6TNFRSF19-HPRD,BioGRID12060722 
TRAF6TICAM1TRIF interacts with TRAF6.BIND14530355 
An unspecified isoform of TRIF interacts with TRAF6. This interaction was modeled on a demonstrated interaction between TRIF from an unspecified species and TRAF from an unspecified species.BIND15474016 
TRAF6TNFAIP3-HPRD,BioGRID9928991 
TRAF6PFASAffinity Capture-MSBioGRID17353931 
TRAF6TUBB2B-HPRD14743216 
TRAF6TJP2Affinity Capture-MSBioGRID17353931 
TRAF6TNFRSF11AAffinity Capture-Western; Reconstituted ComplexBioGRID9685412 |9852070 
|10025951 |10075662 
|11809792 
-HPRD9685412 |10025951 
|10075662 |10635328 
TRAF6HSPA8-HPRD14743216 
TRAF6VCPAffinity Capture-MSBioGRID17353931 
TRAF6CTPSAffinity Capture-MSBioGRID17353931 
TRAF6RIPK2-HPRD,BioGRID9642260 
TRAF6STRADB-HPRD,BioGRID12048196 
TRAF6MAP3K14-HPRD,BioGRID11278268 
NIK interacts with TRAF6. This interaction was modeled on a demonstrated interaction between human NIK and TRAF6 from an unspecified species.BIND9275204 
TRAF6TARSAffinity Capture-MSBioGRID17353931 
TRAF6PSMD12-HPRD,BioGRID14743216 
TRAF6PSMD1-HPRD,BioGRID14743216 
TRAF6VARSAffinity Capture-MSBioGRID17353931 
TRAF6GANABAffinity Capture-MSBioGRID17353931 
TRAF6PSMA4-HPRD14743216 
TRAF6IL17RB-HPRD,BioGRID10748240 
TRAF6TUBA3C-HPRD14743216 
TRAF6SRC-HPRD,BioGRID10635328 
TRAF6RNF126-HPRD14743216 
TRAF6PSMC3Affinity Capture-MSBioGRID14743216 
TRAF6PSMD13Affinity Capture-MSBioGRID14743216 
TRAF6TNFSF11-HPRD10635328 
TRAF6PAICSAffinity Capture-MSBioGRID17353931 
TRAF6ASXL2Affinity Capture-MSBioGRID17353931 
TRAF6MAP3K7IP1-HPRD,BioGRID10094049 
TRAF6MAST2-HPRD,BioGRID15308666 
TRAF6SYK-HPRD,BioGRID11418661 
TRAF6DDX3XAffinity Capture-MSBioGRID17353931 
TRAF6NTSR1-HPRD10514511 
TIFATRAF2Two-hybridBioGRID16189514 
-HPRD11798190 
TIFASDCBP2Two-hybridBioGRID16189514 
TIFATRAF2Two-hybridBioGRID16189514 
-HPRD11798190 
TIFADVL2Two-hybridBioGRID16189514 
TIFANUDT18Two-hybridBioGRID16189514 
TIFANIF3L1Two-hybridBioGRID16189514 
TIFALNX1Two-hybridBioGRID16189514 
TIFAAP1M1Two-hybridBioGRID16189514 
IL1RAPIL1R2-HPRD9862719 
IL1RAPPIK3R1-HPRD,BioGRID10373529 
IL1RAPIL1B-HPRD9820540 
IL1RAPRAC1-HPRD,BioGRID11416133 
IL1RAPIL18R1-HPRD,BioGRID8626725 
IL1RAPIL1R1-HPRD,BioGRID9371760 
IL1RAPSTAT3-HPRD,BioGRID9923604 
IL1RAPIL1A-HPRD9820540 
PRKCZPDPK1PRKCZ (PKCZ) interacts with PDPK1 (PDK1). This interaction was modelled on a demonstrated interaction between human PRKCZ and rat PDPK1.BIND11781095 
An unspecified isoform of PDPK1 (PDK1) phosphorylates PRKCZ (PKC-zeta). This interaction was modeled on a demonstrated interaction between PDPK1 from an unspecified species and PRKCZ from an unspecified species.BIND12223477 
-HPRD,BioGRID9748166 |10764742 
|11781095 
PRKCZAFAP1-HPRD12134071 
PRKCZKRT10-HPRD,BioGRID11585925 
PRKCZTIAM1Biochemical ActivityBioGRID10212259 
PRKCZPPP3CA-HPRD12021260 
PRKCZC1QBP-HPRD,BioGRID10831594 
PRKCZPAWRPar-4 interacts with PKC-zeta. This interaction was modelled on a demonstrated interaction between human Par-4 and rat PKC-zeta.BIND8797824 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID8797824 
PRKCZIRS4-HPRD12774026 
PRKCZFEZ1-HPRD,BioGRID9971736 
PRKCZRAF1-HPRD,BioGRID10620507 
PRKCZPRKCSHPRKCZ (PKCZ) interacts with PRKCSH (80K-H).BIND15707389 
PRKCZYWHAGAffinity Capture-WesternBioGRID10620507 
PRKCZPARD3Affinity Capture-WesternBioGRID12459187 
PRKCZYWHAB-HPRD,BioGRID10620507 
PRKCZPPP1R14A-HPRD15003508 
PRKCZPDPK1PRKCZ (PKCZ) interacts with PDPK1 (PDK1). This interaction was modelled on a demonstrated interaction between human PRKCZ and rat PDPK1.BIND11781095 
An unspecified isoform of PDPK1 (PDK1) phosphorylates PRKCZ (PKC-zeta). This interaction was modeled on a demonstrated interaction between PDPK1 from an unspecified species and PRKCZ from an unspecified species.BIND12223477 
-HPRD,BioGRID9748166 |10764742 
|11781095 
PRKCZCDC42-HPRD10733591 
PRKCZDAPK3Reconstituted ComplexBioGRID12242277 
PRKCZYWHAHAffinity Capture-WesternBioGRID10620507 
PRKCZECT2Affinity Capture-WesternBioGRID15254234 
PRKCZHNRNPA1PKC-zeta phosphorylates and interacts with hnRNPA1. This interaction was modeled on a demonstrated interaction between PKC-zeta and hnRNPA1, both from unspecified species.BIND10383403 
PRKCZPDPK1PRKCZ (PKCZ) interacts with PDPK1 (PDK1). This interaction was modelled on a demonstrated interaction between human PRKCZ and rat PDPK1.BIND11781095 
An unspecified isoform of PDPK1 (PDK1) phosphorylates PRKCZ (PKC-zeta). This interaction was modeled on a demonstrated interaction between PDPK1 from an unspecified species and PRKCZ from an unspecified species.BIND12223477 
-HPRD,BioGRID9748166 |10764742 
|11781095 
PRKCZSRC-HPRD,BioGRID10527887 
PRKCZPDLIM7-HPRD8940095 
PRKCZNCL-HPRD,BioGRID9388266 
PRKCZWWC1-HPRD,BioGRID15081397 
PRKCZYWHAZBiochemical Activity; Reconstituted ComplexBioGRID10620507 |12893243 
PRKCZADCY5-HPRD8206971 
PRKCZYWHAQAffinity Capture-Western; Biochemical Activity; Reconstituted ComplexBioGRID10620507 
PRKCZGRB14-HPRD,BioGRID12242277 
PRKCZMBPPKC-zeta phosphorylates and interacts with MBP. This interaction was modeled on a demonstrated interaction between PKC-zeta and MBP, both from unspecified species.BIND10383403 
PRKCZFEZ2-HPRD,BioGRID14697253 
PRKCZHABP4-HPRD14699138 
PRKCZRPS6KB1Affinity Capture-WesternBioGRID16931574 
PRKCZMAP2K5-HPRD,BioGRID11158308 
PRKCZADAP1-HPRD,BioGRID12893243 
PRKCZAKT3-HPRD,BioGRID12162751 
PRKCZCSNK2B-HPRD,BioGRID10764587 
PRKCZPARD6A-HPRD,BioGRID11260256 
PRKCZPARD6G-HPRD,BioGRID11260256 
PRKCZNFATC2-HPRD,BioGRID12021260 
PRKCZPAWRPar-4 interacts with PKC-zeta. This interaction was modelled on a demonstrated interaction between human Par-4 and rat PKC-zeta.BIND8797824 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID8797824 
PRKCZRELA-HPRD,BioGRID11684013 
IRAK1BP1RELA-HPRD15485901 
PELI3MAP3K7-HPRD12874243 
PELI3MAP3K14-HPRD12874243 
AKT1MAPK14Affinity Capture-Western; Biochemical ActivityBioGRID11042204 
AKT1PAK1Reconstituted ComplexBioGRID14749719 
AKT1MDM2HDM2 interacts with and is phosphorylated by Akt.BIND11960368 
AKT1YWHAZ-HPRD,BioGRID11956222 
Akt interaction with and phosphorylation of 14-3-3 zeta at the same residue as MAPKAPK2.BIND11956222 
AKT1IMPDH2The pleckstrin homology domain of PKB/Akt-alpha interacts with IMPDH type II.BIND10930578 
-HPRD,BioGRID10930578 
AKT1ARAkt phosphorylates AR.BIND11404460 |12621049 
Affinity Capture-Western; Reconstituted ComplexBioGRID11404460 
AKT1NR4A1-HPRD,BioGRID11274386 
AKT1FOXO4-HPRD11313479 
AKT1 interacts with MLLT7 (FOXO4). This interaction was modelled on a demonstrated interaction between human AKT1 and FOXO4 from an unspecified species.BIND15688030 
AKT1ARHGAP29Two-hybridBioGRID14749388 
AKT1SMAD3Affinity Capture-WesternBioGRID16362038 
AKT1RPS6KB1-HPRD11438723 
Co-purificationBioGRID15149849 
AKT1YWHAZ-HPRD,BioGRID11956222 
Akt interaction with and phosphorylation of 14-3-3 zeta at the same residue as MAPKAPK2.BIND11956222 
AKT1SMAD4Affinity Capture-WesternBioGRID16362038 
AKT1PEA15Akt interacts with PED.BIND12808093 
AKT1TSC1-HPRD,BioGRID12167664 
AKT1HSP90AA1-HPRD,BioGRID10995457 
AKT1PDPK1-HPRD,BioGRID11825911 
PDK1 phosphorylates Akt1.BIND15718470 
AKT1TRIB3Affinity Capture-Western; Reconstituted ComplexBioGRID12791994 
AKT1TCL1B-HPRD,BioGRID10983986 
TCL1B interacts with AKT1.BIND11707444 
AKT1TSC2-HPRD,BioGRID12167664 
Akt interacts with and phosphorylates tuberin. This interaction was modelled on a demonstrated interaction between Akt from an unspecified species and human Tuberin.BIND12150915 
AKT1RICSBiochemical ActivityBioGRID12446789 
AKT1MAP2K4-HPRD,BioGRID11707464 
AKT1PDK1PDK1 interacts with and phosphorylates Akt1. This interaction was modeled on a demonstrated interaction between PDK1 and Akt1, both from unspecified species.BIND15678105 
AKT1BRAF-HPRD,BioGRID10869359 
AKT1KTN1Two-hybridBioGRID11162552 
AKT1HSP90AB1Affinity Capture-WesternBioGRID10995457 
AKT1PHLPPPHLPP interacts with Akt. This interaction was modelled on a demonstrated interaction between human PHLPP and Akt from an unspecified species.BIND15808505 
AKT1MAP3K8-HPRD,BioGRID12138205 
AKT1ARFIP2Two-hybridBioGRID9312003 
AKT1CSNK2A1CK2 interacts with and phosphorylates Akt. This interaction was modeled on a demonstrated interaction between human CK2 and Akt from an unspecified species and mouse.BIND15818404 
AKT1PTPN1-HPRD11579209 
AKT1FANCATwo-hybridBioGRID14499622 
AKT1PDPK1-HPRD,BioGRID11825911 
PDK1 phosphorylates Akt1.BIND15718470 
AKT1YBX1Akt-1 interacts with and phosphorylates YB-1.BIND15806160 
AKT1PAK6Reconstituted ComplexBioGRID11773441 
AKT1PKN2-HPRD,BioGRID10926925 
AKT1RICTORReconstituted ComplexBioGRID15718470 
AKT1GSK3BAKT1 interacts with and phosphorylates GSK3B. This interaction was modelled on a demonstrated interaction between human AKT1 and GSK3B from an unspecified species.BIND15688030 
Reconstituted ComplexBioGRID16009706 
AKT1SMAD7Affinity Capture-WesternBioGRID16362038 
AKT1MAPKAPK2-HPRD,BioGRID11042204 
AKT1TCL1A-HPRD10983986 |12009899 
Affinity Capture-Western; Reconstituted ComplexBioGRID10983986 |11707444 
|12009899 
TCL1 interacts with AKT1.BIND11707444 
AKT1RPS6KB1-HPRD11438723 
Co-purificationBioGRID15149849 
AKT1KRT10-HPRD,BioGRID11585925 
AKT1PLXNA1-HPRD,BioGRID15187088 
AKT1MAP3K11-HPRD,BioGRID12458207 
AKT1TERTAffinity Capture-WesternBioGRID15843522 
AKT1PRKCQ-HPRD,BioGRID11410591 
AKT1CDKN1BAffinity Capture-Western; Biochemical ActivityBioGRID12042314 
AKT1CHN2Reconstituted ComplexBioGRID11278894 
AKT1ARAkt phosphorylates AR.BIND11404460 |12621049 
Affinity Capture-Western; Reconstituted ComplexBioGRID11404460 
AKT1AKTIP-HPRD,BioGRID14749367 
AKT1IRS1-HPRD,BioGRID10497255 
AKT1MTCP1-HPRD,BioGRID11707444 
AKT1THEM4-HPRD,BioGRID11598301 
AKT1HSPB1Affinity Capture-WesternBioGRID11042204 
AKT1MAPK8IP1-HPRD,BioGRID12194869 
AKT1IMPDH2The pleckstrin homology domain of PKB/Akt-alpha interacts with IMPDH type II.BIND10930578 
-HPRD,BioGRID10930578 
AKT1RAF1-HPRD,BioGRID10576742 
AKT1BRCA1Reconstituted ComplexBioGRID10542266 
AKT1APPL1APPL interacts with Akt1.BIND10490823 
AKT1BADReconstituted ComplexBioGRID11500364 
AKT1TCL1A-HPRD10983986 |12009899 
Affinity Capture-Western; Reconstituted ComplexBioGRID10983986 |11707444 
|12009899 
TCL1 interacts with AKT1.BIND11707444 
AKT1TCL1B-HPRD,BioGRID10983986 
TCL1B interacts with AKT1.BIND11707444 
AKT1METTL1Mettl1 interacts with and is phosphorylated by PKB-alpha (Akt)BIND15861136 
AKT1UXS1-HPRD11877387 
AKT1TNFSF11-HPRD10635328 
AKT1TCL1A-HPRD10983986 |12009899 
Affinity Capture-Western; Reconstituted ComplexBioGRID10983986 |11707444 
|12009899 
TCL1 interacts with AKT1.BIND11707444 
AKT1CARHSP1Reconstituted ComplexBioGRID15910284 
AKT1PRKDCDNA-PKcs interacts with Akt1.BIND15678105 
AKT1FOXO4-HPRD11313479 
AKT1 interacts with MLLT7 (FOXO4). This interaction was modelled on a demonstrated interaction between human AKT1 and FOXO4 from an unspecified species.BIND15688030 
AKT1HTTHuntingtin is serine-phosphorylated by Akt.BIND12062094 
AKT1GAB2-HPRD,BioGRID11782427 
AKT1SMAD2Affinity Capture-WesternBioGRID16362038 
AKT1NCF1CAkt interaction with and phosphorylation of p47-phoxBIND12734380 
AKT1GSK3BAKT1 interacts with and phosphorylates GSK3B. This interaction was modelled on a demonstrated interaction between human AKT1 and GSK3B from an unspecified species.BIND15688030 
Reconstituted ComplexBioGRID16009706 
AKT1TSC2-HPRD,BioGRID12167664 
Akt interacts with and phosphorylates tuberin. This interaction was modelled on a demonstrated interaction between Akt from an unspecified species and human Tuberin.BIND12150915 
AKT1ILK-HPRD,BioGRID9736715 
AKT1GRB10-HPRD11809791 
AKT1PIAS2Miz1 interacts with Akt.BIND15580267 
AKT1FRAP1Protein-peptide; Reconstituted ComplexBioGRID10910062 |14970221 
|15718470 
AKT1MAPKAP1Affinity Capture-WesternBioGRID16962653 
IKBKBNFKBIAIKK-beta interacts with and phosphorylates I-kappa-B-alpha.BIND9346485 
IKK-beta interacts with and phosphorylates I-kappa-B-alpha. This interaction was modelled on a demonstrated interaction between IKK-beta and I-kappa-B-alpha both from unspecified species.BIND15808510 
Reconstituted ComplexBioGRID9751059 |9891086 
IKK-beta phosphorylates I-kappa-Ba. This interaction was modelled on a demonstrated interaction between IKK-beta from unknown species and I-kappa-Ba from unknown species.BIND15084260 
IKBKBPRKCQPKC-theta interacts with IKK-beta.BIND15802604 
-HPRD,BioGRID11120819 
IKBKBMAP3K11-HPRD,BioGRID10713178 
IKBKBIKBKAPIKAP interacts with IKK-beta.BIND9751059 
-HPRD,BioGRID9751059 
IKBKBCDC37Co-purification; Reconstituted ComplexBioGRID11864612 
IKK-beta interacts with Cdc37. This interaction was modeled on a demonstrated interaction between IKK-beta from an unspecified species and human Cdc37.BIND11864612 
IKBKBIRS1Affinity Capture-WesternBioGRID12351658 
IKBKBPRKDCBiochemical ActivityBioGRID9632806 
IKBKBTNFRSF1A-HPRD,BioGRID10755617 
IKBKBCDC37Co-purification; Reconstituted ComplexBioGRID11864612 
IKK-beta interacts with Cdc37. This interaction was modeled on a demonstrated interaction between IKK-beta from an unspecified species and human Cdc37.BIND11864612 
IKBKBMAP3K14IKK-beta interacts with NIK. This interaction was modeled on a demonstrated interaction between human IKK-beta and NIK from an unspecified species.BIND9346485 
-HPRD,BioGRID9346485 
IKBKBIKBKAPIKAP interacts with IKK-beta.BIND9751059 
-HPRD,BioGRID9751059 
IKBKBNCOA3-HPRD,BioGRID11971985 
IKBKBMAP3K13-HPRD,BioGRID12492477 
IKBKBHSP90AA1-HPRD11864612 
IKBKBIKBKG-HPRD,BioGRID10968790 
NEMO interacts with IKK-beta.BIND15802604 
IKBKBHSPA8-HPRD14743216 
IKBKBTRAF3IP2-HPRD,BioGRID10962033 
IKBKBFOXO3IKK-beta interacts with and phosphorylates FOXO3a.BIND15084260 
IKBKBNFKBIAIKK-beta interacts with and phosphorylates I-kappa-B-alpha.BIND9346485 
IKK-beta interacts with and phosphorylates I-kappa-B-alpha. This interaction was modelled on a demonstrated interaction between IKK-beta and I-kappa-B-alpha both from unspecified species.BIND15808510 
Reconstituted ComplexBioGRID9751059 |9891086 
IKK-beta phosphorylates I-kappa-Ba. This interaction was modelled on a demonstrated interaction between IKK-beta from unknown species and I-kappa-Ba from unknown species.BIND15084260 
IKBKBTUBB2B-HPRD14743216 
IKBKBCTNNB1-HPRD,BioGRID11527961 
IKBKBCASP8-HPRD,BioGRID11002417 
IKBKBNFKBIBIKK-beta phosphorylates I-kappa-B-beta.BIND9346485 
IKBKBBTRCAffinity Capture-WesternBioGRID11158290 
IKBKBIKBKG-HPRD,BioGRID10968790 
NEMO interacts with IKK-beta.BIND15802604 
IKBKBNFKBIAIKK-beta interacts with and phosphorylates I-kappa-B-alpha.BIND9346485 
IKK-beta interacts with and phosphorylates I-kappa-B-alpha. This interaction was modelled on a demonstrated interaction between IKK-beta and I-kappa-B-alpha both from unspecified species.BIND15808510 
Reconstituted ComplexBioGRID9751059 |9891086 
IKK-beta phosphorylates I-kappa-Ba. This interaction was modelled on a demonstrated interaction between IKK-beta from unknown species and I-kappa-Ba from unknown species.BIND15084260 
IKBKBNFKB1-HPRD10469655|11158290 
Affinity Capture-Western; Biochemical ActivityBioGRID10469655 |11158290 
IKBKBTRAF2-HPRD,BioGRID11359906 
IKBKBEIF2AK2-HPRD,BioGRID10848580 
IKBKBNFKB1-HPRD10469655|11158290 
Affinity Capture-Western; Biochemical ActivityBioGRID10469655 |11158290 
IKBKBFANCA-HPRD,BioGRID12210728 
IKBKBPRDX3Affinity Capture-WesternBioGRID12492477 
IKBKBTUBA3C-HPRD14743216 
IKBKBTANK-HPRD12133833 
IKBKBCFLAR-HPRD11002417 
IKBKBBIRC3The cIAP-2 promoter interacts with IKK-beta.BIND15494311 
IKBKBPRKCQPKC-theta interacts with IKK-beta.BIND15802604 
-HPRD,BioGRID11120819 
IKBKBIL8The IL-8 promoter interacts with IKK-beta.BIND15494311 
IKBKBMAP3K14IKK-beta interacts with NIK. This interaction was modeled on a demonstrated interaction between human IKK-beta and NIK from an unspecified species.BIND9346485 
-HPRD,BioGRID9346485 
IKBKBPPM1BAffinity Capture-Western; Biochemical ActivityBioGRID14585847 
IKBKBTRPC4APAffinity Capture-WesternBioGRID14585990 
IKBKBTNFAIP3-HPRD,BioGRID11594795 
IKBKBNFKBIAIKK-beta interacts with and phosphorylates I-kappa-B-alpha.BIND9346485 
IKK-beta interacts with and phosphorylates I-kappa-B-alpha. This interaction was modelled on a demonstrated interaction between IKK-beta and I-kappa-B-alpha both from unspecified species.BIND15808510 
Reconstituted ComplexBioGRID9751059 |9891086 
IKK-beta phosphorylates I-kappa-Ba. This interaction was modelled on a demonstrated interaction between IKK-beta from unknown species and I-kappa-Ba from unknown species.BIND15084260 
FADDEZRCo-purificationBioGRID15659383 
FADDRHOACo-purificationBioGRID15659383 
FADDCFLARMRIT-beta-1 interacts with FADD. This interaction was modelled on a demonstrated interaction between human MRIT-beta-1 and FADD from an unspecified species.BIND9326610 
-HPRD9208847 |11965497 
c-FLIP interacts with FADD.BIND12220669 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID9208847 |9228018 
|9326610 
FADDDAP3-HPRD,BioGRID11376335 |11753396 
FADDXPO5-HPRD12702765 
FADDCFLARMRIT-beta-1 interacts with FADD. This interaction was modelled on a demonstrated interaction between human MRIT-beta-1 and FADD from an unspecified species.BIND9326610 
-HPRD9208847 |11965497 
c-FLIP interacts with FADD.BIND12220669 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID9208847 |9228018 
|9326610 
FADDMOBKL3Two-hybridBioGRID16169070 
FADDMAPK8Co-purificationBioGRID15659383 
FADDTNFRSF10A-HPRD,BioGRID9430227 |11376335 
FADDFASFas interacts with FADD.BIND15383280 
An unspecified isoform of Fas interacts with FADD.BIND15665818 
-HPRD,BioGRID7538907 |8967952 
-HPRD7536190 |7538907 
|8967952|7538907 |8967952 
FADDMSNCo-purificationBioGRID15659383 
FADDPEA15-HPRD,BioGRID10442631 |10493725 
FADDRYBPAffinity Capture-WesternBioGRID11395500 
FADDBIDCo-purificationBioGRID15659383 
FADDTNFRSF10B-HPRD,BioGRID9430227 
FADDTNFRSF1AAffinity Capture-Western; Co-purificationBioGRID8565075 |15659383 
FADDRIPK1Two-hybridBioGRID11854271 
-HPRD11002422 
FADDFASFas interacts with FADD.BIND15383280 
An unspecified isoform of Fas interacts with FADD.BIND15665818 
-HPRD,BioGRID7538907 |8967952 
-HPRD7536190 |7538907 
|8967952|7538907 |8967952 
FADDCFLARMRIT-beta-1 interacts with FADD. This interaction was modelled on a demonstrated interaction between human MRIT-beta-1 and FADD from an unspecified species.BIND9326610 
-HPRD9208847 |11965497 
c-FLIP interacts with FADD.BIND12220669 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID9208847 |9228018 
|9326610 
FADDFASFas interacts with FADD.BIND15383280 
An unspecified isoform of Fas interacts with FADD.BIND15665818 
-HPRD,BioGRID7538907 |8967952 
-HPRD7536190 |7538907 
|8967952|7538907 |8967952 
FADDDEDD-HPRD,BioGRID9774341 
FADDRIPK1Two-hybridBioGRID11854271 
-HPRD11002422 
FADDABCA1-HPRD,BioGRID12235128 
FADDCFLARMRIT-beta-1 interacts with FADD. This interaction was modelled on a demonstrated interaction between human MRIT-beta-1 and FADD from an unspecified species.BIND9326610 
-HPRD9208847 |11965497 
c-FLIP interacts with FADD.BIND12220669 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID9208847 |9228018 
|9326610 
FADDFASFas interacts with FADD.BIND15383280 
An unspecified isoform of Fas interacts with FADD.BIND15665818 
-HPRD,BioGRID7538907 |8967952 
-HPRD7536190 |7538907 
|8967952|7538907 |8967952 
FADDCASP8CASP8 (caspase-8) interacts with FADD.BIND15782135 
-HPRD,BioGRID12107169 
-HPRD11717445 |12107169|12107169 
caspase-8 interacts with FADD.BIND12220669 
FADDTRADDTRADD interacts with FADD. This interaction was modeled on a demonstrated interaction between TRADD and FADD, both from an unspecified speciesBIND12796506 
Affinity Capture-Western; Two-hybridBioGRID8565075 |12911633 
FADD interacts with TRADD.BIND11112409 
TRADD interacts with FADD.BIND15761471 
-HPRD8565075 |10911999 
FADDCASP8CASP8 (caspase-8) interacts with FADD.BIND15782135 
-HPRD,BioGRID12107169 
-HPRD11717445 |12107169|12107169 
caspase-8 interacts with FADD.BIND12220669 
FADDCASP8CASP8 (caspase-8) interacts with FADD.BIND15782135 
-HPRD,BioGRID12107169 
-HPRD11717445 |12107169|12107169 
caspase-8 interacts with FADD.BIND12220669 
FADDTRADDTRADD interacts with FADD. This interaction was modeled on a demonstrated interaction between TRADD and FADD, both from an unspecified speciesBIND12796506 
Affinity Capture-Western; Two-hybridBioGRID8565075 |12911633 
FADD interacts with TRADD.BIND11112409 
TRADD interacts with FADD.BIND15761471 
-HPRD8565075 |10911999 
FADDCASP8AP2-HPRD,BioGRID10235259 
FADDNOL3ARC interacts with FADD.BIND15383280 
Phenotypic SuppressionBioGRID9560245 
FADDCASP10-HPRD9045686 |11717445|11717445 
-HPRD,BioGRID11717445 
FADDNOL3ARC interacts with FADD.BIND15383280 
Phenotypic SuppressionBioGRID9560245 
FADDMBD4-HPRD,BioGRID12702765 
FADDDAPK1-HPRD,BioGRID12911633 
FADDCASP8CASP8 (caspase-8) interacts with FADD.BIND15782135 
-HPRD,BioGRID12107169 
-HPRD11717445 |12107169|12107169 
caspase-8 interacts with FADD.BIND12220669 
FADDSUMO1Two-hybridBioGRID8906799 
FADDNACA-HPRD,BioGRID12684039 
FADDARHGDIACo-purificationBioGRID15659383 
FADDTRADDTRADD interacts with FADD. This interaction was modeled on a demonstrated interaction between TRADD and FADD, both from an unspecified speciesBIND12796506 
Affinity Capture-Western; Two-hybridBioGRID8565075 |12911633 
FADD interacts with TRADD.BIND11112409 
TRADD interacts with FADD.BIND15761471 
-HPRD8565075 |10911999 
FADDCASP10-HPRD9045686 |11717445|11717445 
-HPRD,BioGRID11717445 
FADDHIPK3Affinity Capture-WesternBioGRID11034606 
FADDTRADDTRADD interacts with FADD. This interaction was modeled on a demonstrated interaction between TRADD and FADD, both from an unspecified speciesBIND12796506 
Affinity Capture-Western; Two-hybridBioGRID8565075 |12911633 
FADD interacts with TRADD.BIND11112409 
TRADD interacts with FADD.BIND15761471 
-HPRD8565075 |10911999 
FADDFASLGAffinity Capture-Western; Co-purificationBioGRID12887920 |15659383 
FADDTRADDTRADD interacts with FADD. This interaction was modeled on a demonstrated interaction between TRADD and FADD, both from an unspecified speciesBIND12796506 
Affinity Capture-Western; Two-hybridBioGRID8565075 |12911633 
FADD interacts with TRADD.BIND11112409 
TRADD interacts with FADD.BIND15761471 
-HPRD8565075 |10911999 
FADDLRDD-HPRD,BioGRID10825539 
ITGAMPLAUR-HPRD,BioGRID10744708 
ITGAMCFH-HPRD,BioGRID9558116 
ITGAMJAM3-HPRD,BioGRID12208882 
ITGAMICAM4-HPRD10846180 
ITGAMFGG-HPRD,BioGRID9712878 |11073102 
ITGAMCD14-HPRD9142045 
ITGAMICAM2-HPRD10352278 
ITGAMICAM1-HPRD,BioGRID9488691 |11073102 
ITGAMPRTN3Affinity Capture-WesternBioGRID12960243 
ITGAMAUP1-HPRD,BioGRID12042322 
ITGAMITGB2-HPRD,BioGRID2454931 
ITGAMHP-HPRD11967116 
ITGAMGP1BA-HPRD10899906 
ITGAMC3-HPRD,BioGRID4062888 |11073102 
TOLLIPRBPMSTwo-hybridBioGRID16189514 
TOLLIPTOM1-HPRD,BioGRID14563850 
TOLLIPTLR4-HPRD,BioGRID11751856 
TOLLIPDAZAP2Two-hybridBioGRID16189514 
TOLLIPXRN2Two-hybridBioGRID15231747 
TOLLIPLDB1Two-hybridBioGRID16189514 
TOLLIPZBTB16Two-hybridBioGRID16169070 
TOLLIPSEPT1Two-hybridBioGRID16189514 
TOLLIPSETDB1Two-hybridBioGRID16169070 
TOLLIPZHX1Two-hybridBioGRID16169070 
TOLLIPIL1R1Affinity Capture-WesternBioGRID10854325 
TOLLIPRHOXF2Two-hybridBioGRID16189514 
SQSTM1LCK-HPRD,BioGRID8650207 
SQSTM1SNCA-HPRD11447312 
SQSTM1GABARAPL2Two-hybridBioGRID16189514 
SQSTM1ERCC2-HPRD8652557 
SQSTM1PTPRJ-HPRD9115287 
SQSTM1C14orf139Two-hybridBioGRID16169070 
SQSTM1PRKCI-HPRD,BioGRID9566925 
lamdaPKC interacts with p62. This interaction was modelled on a demonstrated interaction between mouse lamdaPKC and human p62.BIND12813044 
SQSTM1PRKCI-HPRD,BioGRID9566925 
lamdaPKC interacts with p62. This interaction was modelled on a demonstrated interaction between mouse lamdaPKC and human p62.BIND12813044 
SQSTM1NTRK2-HPRD,BioGRID12471037 
SQSTM1RAD23AAffinity Capture-Western; Two-hybridBioGRID16189514 
SQSTM1TTNTitin interacts with p62. This interaction was modelled on a demonstrated interaction between human Titin and rat p62.BIND15802564 
SQSTM1MAP1LC3BTwo-hybridBioGRID16169070 
SQSTM1NR2F2-HPRD8910285 
SQSTM1GABARAPL1Two-hybridBioGRID16189514 
SQSTM1NTRK1Affinity Capture-WesternBioGRID11244088 |12471037 
SQSTM1MAP2K5MEK5 interacts with p62. This interaction was modelled on a demonstrated interaction between mouse MEK5 and human p62.BIND12813044 
SQSTM1RIPK1-HPRD,BioGRID10356400 
HRASRASSF5Reconstituted ComplexBioGRID9488663 
HRASRABAC1-HPRD11335720 
HRASRALGDSRas interacts with the carboxy terminus of RalGDS. This interaction was modeled on a demonstrated interaction between human Ras and rat RalGDS.BIND9516482 
Reconstituted Complex; Two-hybridBioGRID7809086 |7972015 
|9038168 |9150145 
|10783161 |10922060 
|15031288 
-HPRD7972015|9038168 
HRASLGALS1-HPRD,BioGRID11709720 
HRASPIK3R1-HPRD,BioGRID10212255 
HRASRAF1-HPRD8530446 |8911690 
Hras interacts with Raf. This interaction was modelled on a demonstrated interaction between Hras and Raf, both from an unspecified species.BIND15705808 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between human Raf and rat Ras.BIND11585923 
RAF1 (C-Raf) interacts with HRAS (Ha-Ras).BIND12620389 
Raf-1 interacts with Ras.BIND15664191 
C-RAF interacts with Ha-Ras.BIND12620389 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between Raf and an unspecified source and human Ras.BIND7523381 |8307946 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID7862125 |7969158 
|8530446 |8628317 
|9150145 |9154803 
|9523700 |10369681 
|10783161 |10882715 
|10922060 |12379659 
|12620389 |14654780 
|14724584 |15031288 
|16803888 
HRASRAF1-HPRD8530446 |8911690 
Hras interacts with Raf. This interaction was modelled on a demonstrated interaction between Hras and Raf, both from an unspecified species.BIND15705808 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between human Raf and rat Ras.BIND11585923 
RAF1 (C-Raf) interacts with HRAS (Ha-Ras).BIND12620389 
Raf-1 interacts with Ras.BIND15664191 
C-RAF interacts with Ha-Ras.BIND12620389 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between Raf and an unspecified source and human Ras.BIND7523381 |8307946 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID7862125 |7969158 
|8530446 |8628317 
|9150145 |9154803 
|9523700 |10369681 
|10783161 |10882715 
|10922060 |12379659 
|12620389 |14654780 
|14724584 |15031288 
|16803888 
HRASPIK3CA-HPRD9150145 
Reconstituted Complex; Two-hybridBioGRID8665852 |10783161 
|14724584 
HRASRAF1-HPRD8530446 |8911690 
Hras interacts with Raf. This interaction was modelled on a demonstrated interaction between Hras and Raf, both from an unspecified species.BIND15705808 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between human Raf and rat Ras.BIND11585923 
RAF1 (C-Raf) interacts with HRAS (Ha-Ras).BIND12620389 
Raf-1 interacts with Ras.BIND15664191 
C-RAF interacts with Ha-Ras.BIND12620389 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between Raf and an unspecified source and human Ras.BIND7523381 |8307946 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID7862125 |7969158 
|8530446 |8628317 
|9150145 |9154803 
|9523700 |10369681 
|10783161 |10882715 
|10922060 |12379659 
|12620389 |14654780 
|14724584 |15031288 
|16803888 
HRASCDC25A-HPRD7744247 
HRASTIAM1-HPRD,BioGRID12134164 
HRASARHGEF1Biochemical ActivityBioGRID12581858 
HRASMLLT4-HPRD,BioGRID10922060 
HRASSHOC2-HPRD,BioGRID9674433 |10783161 
HRASSOS1-HPRD9690470 |11560935 
Co-crystal StructureBioGRID9690470 |12628188 
HRASBRAF-HPRD,BioGRID7706312 
HRASPIK3CA-HPRD9150145 
Reconstituted Complex; Two-hybridBioGRID8665852 |10783161 
|14724584 
HRASGRB2-HPRD11352655 
HRASERBB2IP-HPRD,BioGRID12379659 
HRASGRIN1-HPRD10862698 
HRASRAF1-HPRD8530446 |8911690 
Hras interacts with Raf. This interaction was modelled on a demonstrated interaction between Hras and Raf, both from an unspecified species.BIND15705808 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between human Raf and rat Ras.BIND11585923 
RAF1 (C-Raf) interacts with HRAS (Ha-Ras).BIND12620389 
Raf-1 interacts with Ras.BIND15664191 
C-RAF interacts with Ha-Ras.BIND12620389 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between Raf and an unspecified source and human Ras.BIND7523381 |8307946 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID7862125 |7969158 
|8530446 |8628317 
|9150145 |9154803 
|9523700 |10369681 
|10783161 |10882715 
|10922060 |12379659 
|12620389 |14654780 
|14724584 |15031288 
|16803888 
HRASRAF1-HPRD8530446 |8911690 
Hras interacts with Raf. This interaction was modelled on a demonstrated interaction between Hras and Raf, both from an unspecified species.BIND15705808 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between human Raf and rat Ras.BIND11585923 
RAF1 (C-Raf) interacts with HRAS (Ha-Ras).BIND12620389 
Raf-1 interacts with Ras.BIND15664191 
C-RAF interacts with Ha-Ras.BIND12620389 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between Raf and an unspecified source and human Ras.BIND7523381 |8307946 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID7862125 |7969158 
|8530446 |8628317 
|9150145 |9154803 
|9523700 |10369681 
|10783161 |10882715 
|10922060 |12379659 
|12620389 |14654780 
|14724584 |15031288 
|16803888 
HRASRGL4-HPRD,BioGRID12874025 
HRASRAF1-HPRD8530446 |8911690 
Hras interacts with Raf. This interaction was modelled on a demonstrated interaction between Hras and Raf, both from an unspecified species.BIND15705808 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between human Raf and rat Ras.BIND11585923 
RAF1 (C-Raf) interacts with HRAS (Ha-Ras).BIND12620389 
Raf-1 interacts with Ras.BIND15664191 
C-RAF interacts with Ha-Ras.BIND12620389 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between Raf and an unspecified source and human Ras.BIND7523381 |8307946 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID7862125 |7969158 
|8530446 |8628317 
|9150145 |9154803 
|9523700 |10369681 
|10783161 |10882715 
|10922060 |12379659 
|12620389 |14654780 
|14724584 |15031288 
|16803888 
HRASARAFARAF (A-Raf) interacts with an unspecified isoform of HRAS (Ha-Ras).BIND12620389 
HRASMAPK8-HPRD8137421 |11525649 
HRASRASA1-HPRD,BioGRID7628625 |9219684 
-HPRD2833817 |7628625 
|8663024 |9219684 
HRASRALGDSRas interacts with the carboxy terminus of RalGDS. This interaction was modeled on a demonstrated interaction between human Ras and rat RalGDS.BIND9516482 
Reconstituted Complex; Two-hybridBioGRID7809086 |7972015 
|9038168 |9150145 
|10783161 |10922060 
|15031288 
-HPRD7972015|9038168 
HRASGPSM2-HPRD,BioGRID12748287 
HRASRAF1-HPRD8530446 |8911690 
Hras interacts with Raf. This interaction was modelled on a demonstrated interaction between Hras and Raf, both from an unspecified species.BIND15705808 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between human Raf and rat Ras.BIND11585923 
RAF1 (C-Raf) interacts with HRAS (Ha-Ras).BIND12620389 
Raf-1 interacts with Ras.BIND15664191 
C-RAF interacts with Ha-Ras.BIND12620389 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between Raf and an unspecified source and human Ras.BIND7523381 |8307946 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID7862125 |7969158 
|8530446 |8628317 
|9150145 |9154803 
|9523700 |10369681 
|10783161 |10882715 
|10922060 |12379659 
|12620389 |14654780 
|14724584 |15031288 
|16803888 
HRASRGL2Reconstituted Complex; Two-hybridBioGRID8939933 |15031288 
HRASIKZF3-HPRD,BioGRID10369681 
HRASRASA1-HPRD,BioGRID7628625 |9219684 
-HPRD2833817 |7628625 
|8663024 |9219684 
HRASPIK3CDTwo-hybridBioGRID10922060 
HRASRASSF1-HPRD,BioGRID10998413 
HRASRAP1GDS1-HPRD,BioGRID11948427 
HRASVAV1-HPRD8554611 
HRASNF1-HPRD,BioGRID8628317 
HRASBCL2-HPRD10490827 
HRASAPBB1IPRIAM interacts with Ras.BIND15469846 
HRASDGKZ-HPRD,BioGRID11257115 
HRASRHEBAffinity Capture-WesternBioGRID15854902 
HRASBRAPIMP interacts with Ras.BIND14724641 
HRASRIN1Reconstituted Complex; Two-hybridBioGRID7862125 |15031288 
-HPRD7862125 |9144171 
HRASRIN1Reconstituted Complex; Two-hybridBioGRID7862125 |15031288 
-HPRD7862125 |9144171 
HRASMAP2K1-HPRD,BioGRID7969158 
HRASPDE6D-HPRD,BioGRID11980706 
HRASRAF1-HPRD8530446 |8911690 
Hras interacts with Raf. This interaction was modelled on a demonstrated interaction between Hras and Raf, both from an unspecified species.BIND15705808 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between human Raf and rat Ras.BIND11585923 
RAF1 (C-Raf) interacts with HRAS (Ha-Ras).BIND12620389 
Raf-1 interacts with Ras.BIND15664191 
C-RAF interacts with Ha-Ras.BIND12620389 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between Raf and an unspecified source and human Ras.BIND7523381 |8307946 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID7862125 |7969158 
|8530446 |8628317 
|9150145 |9154803 
|9523700 |10369681 
|10783161 |10882715 
|10922060 |12379659 
|12620389 |14654780 
|14724584 |15031288 
|16803888 
HRASTTC1-HPRD,BioGRID12748287 
HRASZBTB12-HPRD8939933 
HRASSOS1-HPRD9690470 |11560935 
Co-crystal StructureBioGRID9690470 |12628188 
HRASRASSF2-HPRD12732644 
HRASRASIP1-HPRD,BioGRID15031288 
HRASPIK3CG-HPRD,BioGRID11136978 
HRASRALGDSRas interacts with the carboxy terminus of RalGDS. This interaction was modeled on a demonstrated interaction between human Ras and rat RalGDS.BIND9516482 
Reconstituted Complex; Two-hybridBioGRID7809086 |7972015 
|9038168 |9150145 
|10783161 |10922060 
|15031288 
-HPRD7972015|9038168 
HRASPDGFB-HPRD10485711 
HRASRASGRP4-HPRD11880369 
HRASRASGRF1Two-hybridBioGRID9154803 
HRASRALATwo-hybridBioGRID11786539 
HRASPLAUPhenotypic SuppressionBioGRID10402467 
HRASINSR-HPRD,BioGRID3109943 
HRASSOS2-HPRD12628188 
TICAM2IL1R1-HPRD12721283 
TIRP interacts with IL-1R.BIND12721283 
TICAM2IL1R1-HPRD12721283 
TIRP interacts with IL-1R.BIND12721283 
TICAM2IRF7-HPRD14517278 
TICAM2TICAM1TIRP interacts with TRIF.BIND12721283 
-HPRD12721283 |14519765 
TICAM2TICAM1TIRP interacts with TRIF.BIND12721283 
-HPRD12721283 |14519765 
TICAM2TLR3-HPRD14519765 
TICAM2TIRAP-HPRD12721283 
TIRP interacts with TIRAP.BIND12721283 
TICAM2IRF3-HPRD14517278 
TICAM2TLR4-HPRD14517278 |14519765 
|14556004 
TICAM2OPN1LW-HPRD14517278 
TICAM2TIRAP-HPRD12721283 
TIRP interacts with TIRAP.BIND12721283 
TLR2HSP90B1-HPRD11912201 
TLR2CD14-HPRD,BioGRID10395652 
TLR2LY96-HPRD,BioGRID11160242 
TLR2TLR1-HPRD,BioGRID12077222 
TLR2TLR6-HPRD12077222 
NTRK3PTPN1-HPRD,BioGRID12237455 
NTRK3NTF3Reconstituted ComplexBioGRID8621424 
-HPRD9488719 
NTRK3SHC1-HPRD7657612 
Reconstituted ComplexBioGRID10092678 
NTRK3SHC1-HPRD7657612 
Reconstituted ComplexBioGRID10092678 
NTRK3FRS2Reconstituted ComplexBioGRID10092678 
NTRK3PLCG1Reconstituted ComplexBioGRID10092678 
-HPRD7657612 
NTRK3PLCG1Reconstituted ComplexBioGRID10092678 
-HPRD7657612 
NTRK3NGFRAP1-HPRD10764727 
NTRK3KIDINS220-HPRD15167895 
NTRK3NTF3Reconstituted ComplexBioGRID8621424 
-HPRD9488719 
IRAK2IL1R1-HPRD,BioGRID9374458 
IRAK2TIRAP-HPRD,BioGRID11544529 
CHUKNFKBIABiochemical Activity; Reconstituted ComplexBioGRID9252186 |9751059 
IKK-alpha phosphorylates I-kappa-B-alpha.BIND9346485 
Ikk-alpha phosphorylates I-kappa-B-alpha. This interaction was modeled on a demonstrated interaction between human IKK-alpha and I-kappa-B-alpha from an unspecified species.BIND15782119 
CHUKFKBP5FKBP5 (FKBP51) interacts with CHUK (IKK-alpha).BIND14743216 
CHUKMYH14-HPRD14743216 
CHUKCCND1IKK-alpha interacts with cyclin D1 promoter.BIND15808510 
CHUKMYL6-HPRD14743216 
CHUKIKBKGAffinity Capture-Western; in vitro; in vivo; Reconstituted Complex; Two-hybridBioGRID10968790 |11864612 
|11877453 
-HPRD10968790 |12133833 
CHUKNFKB1-HPRD,BioGRID10469655 
CHUKIKBKAPIKAP interacts with IKK-alpha. This interaction was modeled on a demonstrated interaction between human IKAP and IKK-alpha from an unspecified species.BIND9751059 
-HPRD,BioGRID9751059 
CHUKEIF2AK2Affinity Capture-WesternBioGRID10848580 
CHUKPRKCQPKC-theta interacts with IKK-alpha.BIND15802604 
CHUKFANCAAffinity Capture-Western; Two-hybridBioGRID12210728 |14499622 
CHUKCASP8-HPRD,BioGRID11002417 
CHUKRELARELA (p65) interacts with CHUK (I-kappa-B-alpha).BIND15845455 
I-kappa-B-alpha interacts with RelA.BIND15994554 
CHUKMYCIKK-alpha interacts with c-myc promoter.BIND15808510 
CHUKPRKDC-HPRD,BioGRID9632806 
CHUKNFKBIABiochemical Activity; Reconstituted ComplexBioGRID9252186 |9751059 
IKK-alpha phosphorylates I-kappa-B-alpha.BIND9346485 
Ikk-alpha phosphorylates I-kappa-B-alpha. This interaction was modeled on a demonstrated interaction between human IKK-alpha and I-kappa-B-alpha from an unspecified species.BIND15782119 
CHUKNCOR2IKK-alpha phosphorylates SMRT.BIND15494311 
CHUKNLRP4-HPRD,BioGRID12093792 
CHUKAKT2AKT2 interacts with and phosphorylates IKK-alpha. This interaction was modelled on a demonstrated interaction between human AKT2 and IKKalpha from an unspecified species.BIND12048203 
-HPRD,BioGRID12048203 
CHUKBIRC3The cIAP-2 promoter interacts with IKK-alpha.BIND15494311 
CHUKMAP3K11-HPRD,BioGRID10713178 
CHUKTNFRSF1A-HPRD10755617 
CHUKBTRCI-kappa-B-alpha interacts with beta-TrCP.BIND15994554 
CHUKTRAF2-HPRD,BioGRID11359906 
CHUKIRS1-HPRD,BioGRID12351658 
CHUKCTNNB1-HPRD,BioGRID11527961 
CHUKEBAG9IKK-alpha interacts with EBAG9 promoter.BIND15808510 
CHUKAKT2AKT2 interacts with and phosphorylates IKK-alpha. This interaction was modelled on a demonstrated interaction between human AKT2 and IKKalpha from an unspecified species.BIND12048203 
-HPRD,BioGRID12048203 
CHUKNFKBIABiochemical Activity; Reconstituted ComplexBioGRID9252186 |9751059 
IKK-alpha phosphorylates I-kappa-B-alpha.BIND9346485 
Ikk-alpha phosphorylates I-kappa-B-alpha. This interaction was modeled on a demonstrated interaction between human IKK-alpha and I-kappa-B-alpha from an unspecified species.BIND15782119 
CHUKMAP3K14-HPRD,BioGRID9244310 
Ikk-alpha interacts with NIK. This interaction was modeled on a demonstrated interaction between human IKK-alpha and NIK from an unspecified species.BIND9346485 
CHUKTPM3-HPRD14743216 
CHUKTANKIKK-alpha interacts with TANK.BIND12133833 
Affinity Capture-WesternBioGRID12133833 
TANK interacts with IKK-alpha.BIND12133833 
CHUKMAP3K8-HPRD,BioGRID10072079 
CHUKTNFAIP3-HPRD,BioGRID11594795 
CHUKMRCL3-HPRD14743216 
CHUKIKBKGAffinity Capture-Western; in vitro; in vivo; Reconstituted Complex; Two-hybridBioGRID10968790 |11864612 
|11877453 
-HPRD10968790 |12133833 
CHUKUBE2IBiochemical ActivityBioGRID11853669 
CHUKNFKBIB-HPRD9252186 
CHUKTRPC4APAffinity Capture-WesternBioGRID14585990 
CHUKBCL10-HPRD11113112 
CHUKIL8The IL-8 promoter interacts with IKK-alpha.BIND15494311 
CHUKHSP90AA1-HPRD11864612 
CHUKCDC37-HPRD,BioGRID11864612 
IKK-alpha interacts with Cdc37. This interaction was modeled on a demonstrated interaction between IKK-alpha from an unspecified species and human Cdc37.BIND11864612 
CHUKCDC37-HPRD,BioGRID11864612 
IKK-alpha interacts with Cdc37. This interaction was modeled on a demonstrated interaction between IKK-alpha from an unspecified species and human Cdc37.BIND11864612 
CHUKTANKIKK-alpha interacts with TANK.BIND12133833 
Affinity Capture-WesternBioGRID12133833 
TANK interacts with IKK-alpha.BIND12133833 
CHUKTUBA3C-HPRD14743216 
CHUKMAP3K7-HPRD,BioGRID10187861 
CHUKTANKIKK-alpha interacts with TANK.BIND12133833 
Affinity Capture-WesternBioGRID12133833 
TANK interacts with IKK-alpha.BIND12133833 
CHUKUBE2E3-HPRD,BioGRID9409737 
CHUKMAP3K14-HPRD,BioGRID9244310 
Ikk-alpha interacts with NIK. This interaction was modeled on a demonstrated interaction between human IKK-alpha and NIK from an unspecified species.BIND9346485 
CHUKIKBKAPIKAP interacts with IKK-alpha. This interaction was modeled on a demonstrated interaction between human IKAP and IKK-alpha from an unspecified species.BIND9751059 
-HPRD,BioGRID9751059 
CHUKRELARELA (p65) interacts with CHUK (I-kappa-B-alpha).BIND15845455 
I-kappa-B-alpha interacts with RelA.BIND15994554 
CHUKFOXO3IKK-alpha interacts with and phosphorylates FOXO3a. This interaction was modelled on a demonstrated interaction between IKK-alpha from an unknown species and FOXO3a from human.BIND15084260 
CHUKNCOA3Affinity Capture-Western; Biochemical Activity; Reconstituted ComplexBioGRID11971985 
CHUKESR1IKK-alpha interacts with ER-alpha.BIND15808510 
CHUKPPM1BAffinity Capture-WesternBioGRID14585847 
CHUKTRAF3IP2-HPRD,BioGRID10962033 
CHUKTP53-HPRD11805286 
MAP3K7IP2SPTAN1-HPRD14743216 
MAP3K7IP2XIAP-HPRD,BioGRID12048196 
MAP3K7IP2EEF1A2-HPRD14743216 
MAP3K7IP2SEC13-HPRD14743216 
MAP3K7IP2MAP3K7IP1-HPRD,BioGRID14743216 
MAP3K7IP2CALM3-HPRD14743216 
MAP3K7IP2MAP3K7-HPRD,BioGRID11259596 
-HPRD11259596 |14743216 
MAP3K7IP2RUVBL2-HPRD14743216 
MAP3K7IP2MAP3K7-HPRD,BioGRID11259596 
-HPRD11259596 |14743216 
MAP3K7IP2HSPA9-HPRD14743216 
MAP3K7IP2RPL23-HPRD14743216 
MAP3K7IP2UBA52-HPRD14743216 
MAP3K7IP2HSPA8-HPRD14743216 
MAP3K7IP2HSP90AA1-HPRD14743216 
MAP3K7IP2YWHAE-HPRD14743216 
MAP3K7IP2HSPA2-HPRD14743216 
MAP3K7IP2NCOR1Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID12150997 
MAP3K7IP2CAD-HPRD14743216 
MAP3K7IP2HDAC5Reconstituted ComplexBioGRID12150997 
MAP3K7IP2RPS27-HPRD14743216 
MAP3K7IP2FLNA-HPRD14743216 
MAP3K7IP2HSPA1A-HPRD14743216 
MAP3K7IP2RUVBL1-HPRD14743216 
MAP3K7IP2NFKB1Affinity Capture-Western; Reconstituted ComplexBioGRID12150997 
MAP3K7IP2MAP3K7IP3Affinity Capture-WesternBioGRID14633987 
MAP3K7IP2TBL1XReconstituted ComplexBioGRID12150997 
MAP3K7IP2HNRNPH2-HPRD14743216 
MAP3K7IP2HSPA5-HPRD14743216 
MAP3K7IP2CD82An unspecified isoform of MAP3K7IP2 (TAB2) interacts with the CD82 (KAI1) promoter.BIND15829968 
MAP3K7IP2BAG2-HPRD14743216 
MAP3K7IP2DNAJA1-HPRD14743216 
MAP3K7IP2KIAA1967-HPRD14743216 
MAP3K7IP2TNFRSF11A-HPRD,BioGRID11809792 
MAP3K7IP2C1QBP-HPRD14743216 
MAP3K7IP2CSAffinity Capture-MSBioGRID14743216 
MAP3K7IP2TUBA3C-HPRD14743216 
MAP3K7IP2TIMM50-HPRD14743216 
MAP3K7IP2TUBB4-HPRD14743216 
MAP3K7IP2HDAC1Reconstituted ComplexBioGRID12150997 
MAP3K7IP2CLTC-HPRD14743216 
MAP3K7IP2LGALS3BP-HPRD14743216 
MAP3K7IP2HDAC3-HPRD,BioGRID12150997 
SIGIRRIL1R1-HPRD,BioGRID12925853 
SIGIRRENO2Two-hybridBioGRID16169070 
SIGIRRTLR9-HPRD12925853 
SIGIRRTLR5-HPRD12925853 
SIGIRRTLR4-HPRD,BioGRID12925853 


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