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Protein-protein interaction for LYN
 Nodes,
degree=1 |
 Nodes,
degree=2 |
Protein-protein interaction data for gene LYN
| Degree = 1 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| Degree = 2 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| CDK4 | VTA1 | Two-hybrid | BioGRID | 16189514 |
| CDK4 | CDKN2D | Two-hybrid | BioGRID | 16189514 |
| CDK4 | ACTR3B | Affinity Capture-MS | BioGRID | 17353931 |
| CDK4 | RFC1 | - | HPRD,BioGRID | 10353443 |
| CDK4 | BAT3 | Two-hybrid | BioGRID | 16169070 |
| CDK4 | CNOT7 | - | HPRD,BioGRID | 10602502 |
| CDK4 | CDKN2A | p16 interacts with cdk4. This interaction was modeled on a demonstrated interaction between human p16 and cdk4 from an unspecified species. | BIND | 9482104 |
| CDKN2A interacts with CDK4 | BIND | 11556834 | ||
| - | HPRD,BioGRID | 9228064 | ||
| - | HPRD | 9228064 |15232106 | ||
| p16 interacts with CDK4. This interaction was modeled on a demonstrated interaction between human p16 and CDK4 from an unspecified species. | BIND | 10491434 | ||
| p16 interacts with cdk4. | BIND | 8805225 | ||
| CDK4 | CCND1 | - | HPRD | 9150368 |9837900 |
| CDK4 interacts with Cyclin D1. This interaction was modelled on a demonstrated interaction between human CDK4 and Cyclin D1 from an unspecified species. | BIND | 9228064 | ||
| CCND1 (cyclin D1) interacts with CDK4. | BIND | 8662825 | ||
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 8259215 |9837900 |10580009 |11360184 | ||
| CDK4 | CCND2 | CCND2 interacts with CDK4 | BIND | 11291051 |
| - | HPRD,BioGRID | 11358847 | ||
| CDK4 | RB1 | CDK4 phosphorylates Rb carboxy-terminus. This interaction was modelled on a demonstrated interaction between human Rb and mouse CDK4. | BIND | 15241418 |
| CDK4 | ORC3L | - | HPRD | 15232106 |
| CDK4 | GEMIN4 | Affinity Capture-MS | BioGRID | 17353931 |
| CDK4 | BRCA1 | - | HPRD,BioGRID | 9244350 |
| BRCA1 associates with CDK4 | BIND | 9244350 | ||
| CDK4 | SETDB1 | Two-hybrid | BioGRID | 16169070 |
| CDK4 | SMC1A | Affinity Capture-MS | BioGRID | 17353931 |
| CDK4 | BRCA1 | - | HPRD,BioGRID | 9244350 |
| BRCA1 associates with CDK4 | BIND | 9244350 | ||
| CDK4 | CDKN2A | p16 interacts with cdk4. This interaction was modeled on a demonstrated interaction between human p16 and cdk4 from an unspecified species. | BIND | 9482104 |
| CDKN2A interacts with CDK4 | BIND | 11556834 | ||
| - | HPRD,BioGRID | 9228064 | ||
| - | HPRD | 9228064 |15232106 | ||
| p16 interacts with CDK4. This interaction was modeled on a demonstrated interaction between human p16 and CDK4 from an unspecified species. | BIND | 10491434 | ||
| p16 interacts with cdk4. | BIND | 8805225 | ||
| CDK4 | MYC | MYC (c-Myc) interacts with CDK4 promoter. | BIND | 12857727 |
| CDK4 | CCND2 | CCND2 interacts with CDK4 | BIND | 11291051 |
| - | HPRD,BioGRID | 11358847 | ||
| CDK4 | MYOD1 | - | HPRD,BioGRID | 10022835 |10601020 |
| CDK4 | CDKN1B | - | HPRD,BioGRID | 10908655 |
| CDK4 | IFI27 | - | HPRD | 9837900 |
| CDK4 | CDC37 | - | HPRD,BioGRID | 8666233 |8703009 |
| CDK4 | CDKN2A | p16 interacts with cdk4. This interaction was modeled on a demonstrated interaction between human p16 and cdk4 from an unspecified species. | BIND | 9482104 |
| CDKN2A interacts with CDK4 | BIND | 11556834 | ||
| - | HPRD,BioGRID | 9228064 | ||
| - | HPRD | 9228064 |15232106 | ||
| p16 interacts with CDK4. This interaction was modeled on a demonstrated interaction between human p16 and CDK4 from an unspecified species. | BIND | 10491434 | ||
| p16 interacts with cdk4. | BIND | 8805225 | ||
| CDK4 | PSMD10 | - | HPRD,BioGRID | 11779854 |
| CDK4 | RPRM | Affinity Capture-MS | BioGRID | 17353931 |
| CDK4 | CDKN2A | p16 interacts with cdk4. This interaction was modeled on a demonstrated interaction between human p16 and cdk4 from an unspecified species. | BIND | 9482104 |
| CDKN2A interacts with CDK4 | BIND | 11556834 | ||
| - | HPRD,BioGRID | 9228064 | ||
| - | HPRD | 9228064 |15232106 | ||
| p16 interacts with CDK4. This interaction was modeled on a demonstrated interaction between human p16 and CDK4 from an unspecified species. | BIND | 10491434 | ||
| p16 interacts with cdk4. | BIND | 8805225 | ||
| CDK4 | PCNA | Affinity Capture-Western | BioGRID | 8259215 |
| CDK4 | CCND3 | - | HPRD,BioGRID | 10342870 |
| CDK4 | DBNL | Affinity Capture-MS | BioGRID | 17353931 |
| CDK4 | SMC3 | Affinity Capture-MS | BioGRID | 17353931 |
| CDK4 | CDKN2B | - | HPRD | 7478582 |9111314 |9163429 |
| in vitro; in vivo; Two-hybrid | BioGRID | 9163429 |16169070 |16189514 | ||
| CDK4 | PTMA | - | HPRD | 11310559 |
| CDK4 | BIRC5 | - | HPRD,BioGRID | 10713676 |
| CDK4 | CDKN2B | - | HPRD | 7478582 |9111314 |9163429 |
| in vitro; in vivo; Two-hybrid | BioGRID | 9163429 |16169070 |16189514 | ||
| CDK4 | CDKN2C | - | HPRD,BioGRID | 8001816 |
| An unspecified isoform of p18 interacts with cdk4. This interaction was modeled on a demonstrated interaction between human p18 and cdk4 from an unspecified species. | BIND | 9482104 | ||
| CDK4 | UBXN1 | Affinity Capture-MS | BioGRID | 17353931 |
| CDK4 | CCND1 | - | HPRD | 9150368 |9837900 |
| CDK4 interacts with Cyclin D1. This interaction was modelled on a demonstrated interaction between human CDK4 and Cyclin D1 from an unspecified species. | BIND | 9228064 | ||
| CCND1 (cyclin D1) interacts with CDK4. | BIND | 8662825 | ||
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 8259215 |9837900 |10580009 |11360184 | ||
| CDK4 | CDKN2A | p16 interacts with cdk4. This interaction was modeled on a demonstrated interaction between human p16 and cdk4 from an unspecified species. | BIND | 9482104 |
| CDKN2A interacts with CDK4 | BIND | 11556834 | ||
| - | HPRD,BioGRID | 9228064 | ||
| - | HPRD | 9228064 |15232106 | ||
| p16 interacts with CDK4. This interaction was modeled on a demonstrated interaction between human p16 and CDK4 from an unspecified species. | BIND | 10491434 | ||
| p16 interacts with cdk4. | BIND | 8805225 | ||
| CDK4 | CCND1 | - | HPRD | 9150368 |9837900 |
| CDK4 interacts with Cyclin D1. This interaction was modelled on a demonstrated interaction between human CDK4 and Cyclin D1 from an unspecified species. | BIND | 9228064 | ||
| CCND1 (cyclin D1) interacts with CDK4. | BIND | 8662825 | ||
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 8259215 |9837900 |10580009 |11360184 | ||
| CDK4 | SMAD3 | CDK4 phosphorylates Smad3 on Thr8, Thr179, Ser204, Ser208 and Ser213. This interaction was modelled on a demonstrated interaction between Smad3 from an unspecified species and mouse CDK4. | BIND | 15241418 |
| CDK4 | SERTAD1 | - | HPRD,BioGRID | 10580009 |15065884 |
| CDK4 | CCND1 | - | HPRD | 9150368 |9837900 |
| CDK4 interacts with Cyclin D1. This interaction was modelled on a demonstrated interaction between human CDK4 and Cyclin D1 from an unspecified species. | BIND | 9228064 | ||
| CCND1 (cyclin D1) interacts with CDK4. | BIND | 8662825 | ||
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 8259215 |9837900 |10580009 |11360184 | ||
| CDK4 | CDC7 | - | HPRD | 15232106 |
| CDK4 | CAPNS1 | Two-hybrid | BioGRID | 16169070 |
| CDK4 | CDKN2A | p16 interacts with cdk4. This interaction was modeled on a demonstrated interaction between human p16 and cdk4 from an unspecified species. | BIND | 9482104 |
| CDKN2A interacts with CDK4 | BIND | 11556834 | ||
| - | HPRD,BioGRID | 9228064 | ||
| - | HPRD | 9228064 |15232106 | ||
| p16 interacts with CDK4. This interaction was modeled on a demonstrated interaction between human p16 and CDK4 from an unspecified species. | BIND | 10491434 | ||
| p16 interacts with cdk4. | BIND | 8805225 | ||
| CDK4 | CDKN1A | Cdk4 interacts with p21. | BIND | 8999999 |
| CDK4 | CEBPA | - | HPRD,BioGRID | 11684017 |
| CDK4 | CDKN2C | - | HPRD,BioGRID | 8001816 |
| An unspecified isoform of p18 interacts with cdk4. This interaction was modeled on a demonstrated interaction between human p18 and cdk4 from an unspecified species. | BIND | 9482104 | ||
| CDK4 | SMAD2 | CDK4 phosphorylates Smad2. This interaction was modelled on a demonstrated interaction between Smad2 from an unspecified species and mouse CDK4. | BIND | 15241418 |
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