Protein-protein interaction for MKI67

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Protein-protein interaction data for gene MKI67

Degree = 1
Interactor A Interactor B Experimental method Source Pubmed
MKI67CBX1pKi-67 interacts with the CS domain of HP1 protein via its C-terminus. This interaction was modeled on a demonstrated interaction between pKi-67 from human and HP1-beta from mouse.BIND11793364 
MKI67PRKCB-HPRD10502411 
MKI67CDC2Biochemical ActivityBioGRID10502411 
MKI67CBX3pKi-67 interacts with HP1-gamma via its C-terminus. This interaction was modeled on a demonstrated interaction between pKi-67 from human and HP1-gamma from mouse.BIND11793364 
-HPRD,BioGRID12485163 
MKI67KIF15Affinity Capture-Western; Two-hybridBioGRID10878014 
MKI67CBX5-HPRD12485163 
pKi-67 interacts with HP1-alpha protein via its C-terminus. This interaction was modeled on a demonstrated interaction between pKi-67 from human and HP1-alpha from mouse.BIND11793364 

Degree = 2
Interactor A Interactor B Experimental method Source Pubmed
CBX1RB1Reconstituted ComplexBioGRID12711675 
CBX1ARL5ATwo-hybridBioGRID12414990 
CBX1DNMT1-HPRD,BioGRID12711675 
CBX1C1orf103Two-hybridBioGRID16169070 
CBX1UCHL1Two-hybridBioGRID16169070 
CBX1PIM1-HPRD,BioGRID12111331 
CBX1HIST1H3C-HPRD11882902 
CBX1CHAF1A-HPRD10549285 
CBX1TRIM28-HPRD,BioGRID10562550 |11336697 
CBX1SUV39H1-HPRD,BioGRID10202156 
CBX1DNMT3BDNMT3B interacts with HP1-beta. This interaction was modeled on a demonstrated interaction between mouse Dnmt3b1 and human HP1-beta.BIND15120635 
-HPRD,BioGRID12867029 
CBX1RPL12Two-hybridBioGRID16169070 
CBX1TRIM24-HPRD,BioGRID10562550 
CBX1DNMT3BDNMT3B interacts with HP1-beta. This interaction was modeled on a demonstrated interaction between mouse Dnmt3b1 and human HP1-beta.BIND15120635 
-HPRD,BioGRID12867029 
CBX1DNMT3A-HPRD,BioGRID12711675 
CBX1C11orf30-HPRD,BioGRID14651845 
PRKCBRASGRP3Biochemical ActivityBioGRID15213298 
PRKCBBTKReconstituted ComplexBioGRID12679936 
PRKCBZMYND8-HPRD11003709 
PRKCBSPTAN1-HPRD8163551 
PRKCBPDLIM7-HPRD8940095 
PRKCBRIPK4-HPRD,BioGRID11278382 
PRKCBGCNT1-HPRD12765965 
PRKCBPDPK1-HPRD,BioGRID11376011 
PRKCBLMNB1-HPRD,BioGRID11901153 
PRKCBAFAP1-HPRD,BioGRID12134071 
PRKCBYWHAG-HPRD,BioGRID10433554 
PRKCBEIF6-HPRD14654845 
PRKCBCSF2RBAffinity Capture-WesternBioGRID10490850 
PRKCBNCAM1Affinity Capture-WesternBioGRID12743109 
PRKCBMAPK6-HPRD8626698 
PRKCBADRBK1-HPRD12456365 
Affinity Capture-Western; Reconstituted ComplexBioGRID12679936 
PRKCBTIAM1Biochemical ActivityBioGRID10212259 
PRKCBGNB2L1Affinity Capture-Western; Reconstituted ComplexBioGRID10480917 
PRKCBGNA12Biochemical ActivityBioGRID8824244 
PRKCBNCF1Affinity Capture-WesternBioGRID11120743 
PRKCBGNA13-HPRD,BioGRID8824244 
PRKCBHABP4-HPRD14699138 
PRKCBGRIN1-HPRD10862698 
PRKCBADRBK1-HPRD12456365 
Affinity Capture-Western; Reconstituted ComplexBioGRID12679936 
PRKCBSTAT3An unspecified isoform of PKC-beta interacts with Stat3.BIND10446219 
PRKCBRGS2-HPRD,BioGRID11063746 
PRKCBPDLIM5-HPRD,BioGRID8940095 
PRKCBGSK3B-HPRD1324914 
CDC2GADD45B-HPRD10973963 
Cdk1 interacts with Gadd45b. This interaction was modeled on a demonstrated interaction between human Cdk1 and Gadd45b from an unspecified species.BIND12124778 
CDC2CCNB1The cyclin-dependent kinase CDC2 interacts with cyclin B1.BIND9515786 
-HPRD,BioGRID2570636 
CCNB1 (cyclin B1) interacts with CDC2.BIND8662825 
CDC2 interacts with CCNB1 (cyclin B1) to form a complex.BIND8475101 
CCNB1 (CYCB) interacts with CDC2.BIND8463339 
CDC2 (CDK1) interacts with CCNB1 (cyclin B1). This interaction was modeled on a demonstrated interaction between monkey CDC2 and human CCNB1.BIND8070405 
Cyclin B1 interacts with Cdk1.BIND15989971 
CDC2PKMYT1-HPRD10504341 
Myt1 interacts with and phosphorylates Cdc2. This interaction was modelled on a demonstrated interaction between human Myt1 and Cdc2 from an unspecified species.BIND10504341 
CDC2E2F4E2F4 interacts with the Cdc2 promoter.BIND10766737 
E2F4 interacts with CDC2 promoter.BIND15782160 
E2F4 interacts with the CDC2 promoter.BIND15525513 
CDC2TLE1-HPRD12397081 
CDC2FEN1Reconstituted ComplexBioGRID12853968 
CDC2BRCA1-HPRD,BioGRID9244350 
CDC2GORASP1-HPRD12839990 
CDC2TP53-HPRD,BioGRID11327730 
CDC2GADD45ACdk1 interacts with Gadd45a. This interaction was modeled on a demonstrated interaction between human Cdk1 and Gadd45a from an unspecified species.BIND12124778 
-HPRD,BioGRID10973963 
CDC2GADD45ACdk1 interacts with Gadd45a. This interaction was modeled on a demonstrated interaction between human Cdk1 and Gadd45a from an unspecified species.BIND12124778 
-HPRD,BioGRID10973963 
CDC2FANCC-HPRD,BioGRID9242535 
CDC2LYN-HPRD,BioGRID8051175 |8910336 
CDC2SPAG5-HPRD,BioGRID11549262 
CDC2E2F3E2F3 interacts with the Cdc2 promoter.BIND10766737 
CDC2CHAF1B-HPRD10938080 
CDC2LATS1-HPRD,BioGRID9988268 
CDC2GADD45GCdk1 interacts with Gadd45g. This interaction was modeled on a demonstrated interaction between human Cdk1 and Gadd45g from an unspecified species.BIND12124778 
-HPRD10973963 
CDC2MDM4CDC2 interacts with MDM4 (MDMX). This interaction was modeled on a demonstrated interaction between human CDC2, and MDM4 from an unspecified species.BIND15735705 
CDC2CCNB1The cyclin-dependent kinase CDC2 interacts with cyclin B1.BIND9515786 
-HPRD,BioGRID2570636 
CCNB1 (cyclin B1) interacts with CDC2.BIND8662825 
CDC2 interacts with CCNB1 (cyclin B1) to form a complex.BIND8475101 
CCNB1 (CYCB) interacts with CDC2.BIND8463339 
CDC2 (CDK1) interacts with CCNB1 (cyclin B1). This interaction was modeled on a demonstrated interaction between monkey CDC2 and human CCNB1.BIND8070405 
Cyclin B1 interacts with Cdk1.BIND15989971 
CDC2FANCAAffinity Capture-MSBioGRID15082718 
CDC2CDKN1Ap21 interacts with CDC2. This interaction was modeled on a demonstrated interaction between human p21 and hamster CDC2.BIND9467962 
CDC2ERCC2-HPRD8652557 
CDC2CCNA1-HPRD,BioGRID8565853 
CCNA1 (CYCA) interacts with CDC2.BIND8463339 
CDC2E2F4E2F4 interacts with the Cdc2 promoter.BIND10766737 
E2F4 interacts with CDC2 promoter.BIND15782160 
E2F4 interacts with the CDC2 promoter.BIND15525513 
CDC2CCNA2-HPRD10924145 
CCNA2 (Cyclin A) interacts with CDC2.BIND15674323 
The cyclin-dependent kinase CDC2 (cdc2) interacts with cyclin A2 (cyclin A).BIND8423786 
Affinity Capture-WesternBioGRID12853968 
CDC2DAB2-HPRD,BioGRID12881709 
CDC2NSFL1CBiochemical ActivityBioGRID12810701 
CDC2CDC25C-HPRD11836499 
CDC2CNOT7-HPRD,BioGRID10602502 
CDC2FANCGReconstituted ComplexBioGRID15367677 
CDC2E2F4E2F4 interacts with the Cdc2 promoter.BIND10766737 
E2F4 interacts with CDC2 promoter.BIND15782160 
E2F4 interacts with the CDC2 promoter.BIND15525513 
CDC2PIN1-HPRD11774038 
CDC2FYN-HPRD,BioGRID8910336 
CDC2CCNA2-HPRD10924145 
CCNA2 (Cyclin A) interacts with CDC2.BIND15674323 
The cyclin-dependent kinase CDC2 (cdc2) interacts with cyclin A2 (cyclin A).BIND8423786 
Affinity Capture-WesternBioGRID12853968 
CDC2CCNA2-HPRD10924145 
CCNA2 (Cyclin A) interacts with CDC2.BIND15674323 
The cyclin-dependent kinase CDC2 (cdc2) interacts with cyclin A2 (cyclin A).BIND8423786 
Affinity Capture-WesternBioGRID12853968 
CDC2NRF1NRF1 interacts with the CDC2 promoter.BIND15525513 
CDC2CCNB2-HPRD9926943 
The cyclin-dependent kinase CDC2 (p34cdc2) interacts with cyclin B2.BIND7737117 
CDC2 (CDK1) interacts with CCNB2 (cyclin B2). This interaction was modeled on a demonstrated interaction between monkey CDC2 and human CCNB2.BIND8070405 
CDC2GADD45B-HPRD10973963 
Cdk1 interacts with Gadd45b. This interaction was modeled on a demonstrated interaction between human Cdk1 and Gadd45b from an unspecified species.BIND12124778 
CDC2PTMA-HPRD11310559 
CDC2EEF1D-HPRD8051108 
CDC2TSC1Reconstituted ComplexBioGRID14551205 
-HPRD11444800 
CDC2CCNB1The cyclin-dependent kinase CDC2 interacts with cyclin B1.BIND9515786 
-HPRD,BioGRID2570636 
CCNB1 (cyclin B1) interacts with CDC2.BIND8662825 
CDC2 interacts with CCNB1 (cyclin B1) to form a complex.BIND8475101 
CCNB1 (CYCB) interacts with CDC2.BIND8463339 
CDC2 (CDK1) interacts with CCNB1 (cyclin B1). This interaction was modeled on a demonstrated interaction between monkey CDC2 and human CCNB1.BIND8070405 
Cyclin B1 interacts with Cdk1.BIND15989971 
CDC2BCL2Affinity Capture-WesternBioGRID11326318 |11774038 
CDC2ZBTB16-HPRD,BioGRID10497277 
CDC2CCNB1The cyclin-dependent kinase CDC2 interacts with cyclin B1.BIND9515786 
-HPRD,BioGRID2570636 
CCNB1 (cyclin B1) interacts with CDC2.BIND8662825 
CDC2 interacts with CCNB1 (cyclin B1) to form a complex.BIND8475101 
CCNB1 (CYCB) interacts with CDC2.BIND8463339 
CDC2 (CDK1) interacts with CCNB1 (cyclin B1). This interaction was modeled on a demonstrated interaction between monkey CDC2 and human CCNB1.BIND8070405 
Cyclin B1 interacts with Cdk1.BIND15989971 
CDC2CKS2-HPRD2227411 
CDC2LZTS1-HPRD,BioGRID11504921 
CDC2ESPL1Separase interacts with Cdk1.BIND15989971 
CDC2CCNB2-HPRD9926943 
The cyclin-dependent kinase CDC2 (p34cdc2) interacts with cyclin B2.BIND7737117 
CDC2 (CDK1) interacts with CCNB2 (cyclin B2). This interaction was modeled on a demonstrated interaction between monkey CDC2 and human CCNB2.BIND8070405 
CDC2BIRC5-HPRD11069302 
CDC2RPA2-HPRD1318195 
CDC2E2F1E2F1 interacts with the Cdc2 promoter.BIND10766737 
CDC2CCNB1The cyclin-dependent kinase CDC2 interacts with cyclin B1.BIND9515786 
-HPRD,BioGRID2570636 
CCNB1 (cyclin B1) interacts with CDC2.BIND8662825 
CDC2 interacts with CCNB1 (cyclin B1) to form a complex.BIND8475101 
CCNB1 (CYCB) interacts with CDC2.BIND8463339 
CDC2 (CDK1) interacts with CCNB1 (cyclin B1). This interaction was modeled on a demonstrated interaction between monkey CDC2 and human CCNB1.BIND8070405 
Cyclin B1 interacts with Cdk1.BIND15989971 
CDC2CCNB1The cyclin-dependent kinase CDC2 interacts with cyclin B1.BIND9515786 
-HPRD,BioGRID2570636 
CCNB1 (cyclin B1) interacts with CDC2.BIND8662825 
CDC2 interacts with CCNB1 (cyclin B1) to form a complex.BIND8475101 
CCNB1 (CYCB) interacts with CDC2.BIND8463339 
CDC2 (CDK1) interacts with CCNB1 (cyclin B1). This interaction was modeled on a demonstrated interaction between monkey CDC2 and human CCNB1.BIND8070405 
Cyclin B1 interacts with Cdk1.BIND15989971 
CDC2DNM2-HPRD7590285 
CDC2CCNB1The cyclin-dependent kinase CDC2 interacts with cyclin B1.BIND9515786 
-HPRD,BioGRID2570636 
CCNB1 (cyclin B1) interacts with CDC2.BIND8662825 
CDC2 interacts with CCNB1 (cyclin B1) to form a complex.BIND8475101 
CCNB1 (CYCB) interacts with CDC2.BIND8463339 
CDC2 (CDK1) interacts with CCNB1 (cyclin B1). This interaction was modeled on a demonstrated interaction between monkey CDC2 and human CCNB1.BIND8070405 
Cyclin B1 interacts with Cdk1.BIND15989971 
CDC2PKMYT1-HPRD10504341 
Myt1 interacts with and phosphorylates Cdc2. This interaction was modelled on a demonstrated interaction between human Myt1 and Cdc2 from an unspecified species.BIND10504341 
CDC2TSC1Reconstituted ComplexBioGRID14551205 
-HPRD11444800 
CDC2GADD45GCdk1 interacts with Gadd45g. This interaction was modeled on a demonstrated interaction between human Cdk1 and Gadd45g from an unspecified species.BIND12124778 
-HPRD10973963 
CDC2WEE1WEE1 phosphorylates CDC2.BIND15735702 
CDC2LMNB1-HPRD11901153 
CDC2CCNA1-HPRD,BioGRID8565853 
CCNA1 (CYCA) interacts with CDC2.BIND8463339 
CDC2CUX1Biochemical ActivityBioGRID11584018 
CDC2CDKN3-HPRD,BioGRID8127873 
CDC2C13orf15-HPRD11687586 
CDC2PCNA-HPRD7949095 
CDC2SFN-HPRD,BioGRID10524633 
CDC2PITPNM1Nir2 is phosphorylated by Cdk1.BIND15125835 
CDC2HSPA2-HPRD9247342 
CDC2CCNB2-HPRD9926943 
The cyclin-dependent kinase CDC2 (p34cdc2) interacts with cyclin B2.BIND7737117 
CDC2 (CDK1) interacts with CCNB2 (cyclin B2). This interaction was modeled on a demonstrated interaction between monkey CDC2 and human CCNB2.BIND8070405 
CDC2USP16-HPRD10077596 
CDC2CCNA2-HPRD10924145 
CCNA2 (Cyclin A) interacts with CDC2.BIND15674323 
The cyclin-dependent kinase CDC2 (cdc2) interacts with cyclin A2 (cyclin A).BIND8423786 
Affinity Capture-WesternBioGRID12853968 
CDC2CCNE1-HPRD,BioGRID1388288 
CBX3ARL5ATwo-hybridBioGRID12414990 
CBX3LBR-HPRD,BioGRID8663349 
CBX3PIM1-HPRD,BioGRID10664448 
CBX3TRIM28Affinity Capture-Western; in vitro; in vivoBioGRID10562550 |11336697 
CBX3MIS12-HPRD,BioGRID15502821 
Mis12 interacts with HP1-gamma.BIND15502821 
CBX3TRIM24-HPRD,BioGRID10562550 
CBX3DSN1c20orf172 interacts with HP1-gamma.BIND15502821 
-HPRD,BioGRID15502821 
CBX3DSN1c20orf172 interacts with HP1-gamma.BIND15502821 
-HPRD,BioGRID15502821 
CBX3DNMT3BDNMT3B interacts with HP1-gamma. This interaction was modeled on a demonstrated interaction between mouse Dnmt3b1 and human HP1-gamma.BIND15120635 
CBX3MIS12-HPRD,BioGRID15502821 
Mis12 interacts with HP1-gamma.BIND15502821 
CBX3SP100-HPRD,BioGRID9636147 
KIF15CHD3Two-hybridBioGRID16169070 
KIF15VIMTwo-hybridBioGRID16169070 
KIF15KIAA1377Two-hybridBioGRID16169070 
KIF15MAP1LC3ATwo-hybridBioGRID16169070 
CBX5ARL5A-HPRD,BioGRID12414990 
CBX5XRCC6Ku70 interacts with HP1-alpha.BIND11112778 
-HPRD,BioGRID11112778 
CBX5HIST2H3AReconstituted ComplexBioGRID11336697 
CBX5LBR-HPRD,BioGRID8663349 
CBX5TBPAffinity Capture-WesternBioGRID11959914 
CBX5CHAF1A-HPRD10549285 |10938122 
Affinity Capture-Western; Reconstituted ComplexBioGRID10938122 |12697822 
CBX5HDAC1Affinity Capture-WesternBioGRID12242305 
CBX5SMARCA4-HPRD,BioGRID12411497 
CBX5CHAF1A-HPRD10549285 |10938122 
Affinity Capture-Western; Reconstituted ComplexBioGRID10938122 |12697822 
CBX5PRR14Two-hybridBioGRID16189514 
CBX5RB1Affinity Capture-WesternBioGRID11484059 
CBX5HDAC4-HPRD,BioGRID12242305 
CBX5XRCC6Ku70 interacts with HP1-alpha.BIND11112778 
-HPRD,BioGRID11112778 
CBX5E2F1E2F1 interacts with HP1-alpha chromatin.BIND11799066 
CBX5DNMT1Affinity Capture-WesternBioGRID12867029 
CBX5SUV39H1Affinity Capture-Western; Two-hybridBioGRID12242305 |12711603 
|16189514 
-HPRD12565857 |12711603 
CBX5MIS12-HPRD,BioGRID15502821 
Mis12 interacts with HP1-alpha.BIND15502821 
CBX5DNMT3AAffinity Capture-WesternBioGRID12867029 
CBX5HIST3H2BBReconstituted ComplexBioGRID11336697 
CBX5HIST4H4Reconstituted ComplexBioGRID11336697 
CBX5E2F4E2F4 interacts with the HP1-alpha chromatin.BIND11799066 
CBX5DNMT3B-HPRD,BioGRID12867029 
DNMT3B interacts with HP1-alpha. This interaction was modeled on a demonstrated interaction between mouse Dnmt3b1 and human HP1-alpha.BIND15120635 
CBX5DNMT3B-HPRD,BioGRID12867029 
DNMT3B interacts with HP1-alpha. This interaction was modeled on a demonstrated interaction between mouse Dnmt3b1 and human HP1-alpha.BIND15120635 
CBX5SUV39H1Affinity Capture-Western; Two-hybridBioGRID12242305 |12711603 
|16189514 
-HPRD12565857 |12711603 
CBX5CHAF1BTwo-hybridBioGRID12697822 
CBX5TAF4-HPRD,BioGRID11959914 
CBX5INCENPHP1 interacts with INCENP. This interaction was modelled on a demonstrated interaction between human HP1 and chicken INCENP.BIND11516652 
-HPRD9864353 
CBX5DSN1c20orf172 interacts with HP1-alpha.BIND15502821 
-HPRD,BioGRID15502821 
CBX5MIS12-HPRD,BioGRID15502821 
Mis12 interacts with HP1-alpha.BIND15502821 
CBX5TRIM28Affinity Capture-Western; in vitro; in vivo; Reconstituted Complex; Two-hybridBioGRID10562550 |10938122 
|11336697 |12154074 
|12411497 
-HPRD10562550 |12154074 
CBX5MBD1-HPRD,BioGRID12711603 
CBX5INCENPHP1 interacts with INCENP. This interaction was modelled on a demonstrated interaction between human HP1 and chicken INCENP.BIND11516652 
-HPRD9864353 
CBX5HDAC9-HPRD,BioGRID12242305 
CBX5TCEB3BTwo-hybridBioGRID16189514 
CBX5RPSA-HPRD,BioGRID14730304 
CBX5HIST3H2AReconstituted ComplexBioGRID11336697 
CBX5NSL1HP1-alpha interacts with DC8.BIND15502821 
-HPRD,BioGRID15502821 
CBX5TRIM28Affinity Capture-Western; in vitro; in vivo; Reconstituted Complex; Two-hybridBioGRID10562550 |10938122 
|11336697 |12154074 
|12411497 
-HPRD10562550 |12154074 
CBX5DSN1c20orf172 interacts with HP1-alpha.BIND15502821 
-HPRD,BioGRID15502821 
CBX5TRIM24-HPRD,BioGRID10562550 
CBX5HDAC5-HPRD,BioGRID12242305 
CBX5NSL1HP1-alpha interacts with DC8.BIND15502821 
-HPRD,BioGRID15502821 
CBX5BCL11BCTIP2 interacts with HP1-alpha.BIND12692243 


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