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Protein-protein interaction for MMP2
 Nodes,
degree=1 |
 Nodes,
degree=2 |
Protein-protein interaction data for gene MMP2
| Degree = 1 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| MMP2 | THBS1 | - | HPRD,BioGRID | 10900205 |
| MMP2 | SPOCK1 | - | HPRD | 12810672 |
| MMP2 | CLDN1 | - | HPRD | 11382769 |
| MMP2 | TIMP4 | - | HPRD,BioGRID | 9182583 |
| MMP2 | TIMP3 | - | HPRD,BioGRID | 10196161 |
| MMP2 | BCAN | - | HPRD,BioGRID | 10986281 |
| MMP2 | LCN2 | - | HPRD,BioGRID | 7683678 |
| MMP2 | CXCL12 | - | HPRD,BioGRID | 11571304 |
| MMP2 | ITGAV | - | HPRD,BioGRID | 11134507 |
| MMP2 | A2M | Reconstituted Complex | BioGRID | 9344465 |
| MMP2 | THBS2 | - | HPRD,BioGRID | 10900205 |
| MMP2 | COL7A1 | - | HPRD | 10652000 |
| MMP2 | BACE1 | - | HPRD | 12586836 |
| MMP2 | PZP | Reconstituted Complex | BioGRID | 9344465 |
| MMP2 | COL18A1 | - | HPRD,BioGRID | 12023034 |
| MMP2 | MMP17 | - | HPRD,BioGRID | 10551873 |
| MMP2 | TIMP2 | - | HPRD,BioGRID | 9933646 |10991943 |12032297 |12374789 |
| MMP2 | CCL7 | - | HPRD,BioGRID | 10947989 |12149192 |
| MMP2 | TGFB1 | - | HPRD,BioGRID | 10652271 |
| MMP2 | COL6A3 | - | HPRD | 8862926 |
| MMP2 | COL1A1 | - | HPRD,BioGRID | 11368514 |
| Degree = 2 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| THBS1 | LRP2 | Reconstituted Complex | BioGRID | 7775583 |
| THBS1 | DCN | - | HPRD | 1550960 |9328841 |
| THBS1 | F2 | - | HPRD,BioGRID | 2435757 |
| THBS1 | IGFBP5 | Reconstituted Complex | BioGRID | 10698186 |
| IGFBP-5 interacts with TS-1. | BIND | 15700281 | ||
| THBS1 | CORO1A | - | HPRD | 10749676 |
| THBS1 | COL4A1 | Reconstituted Complex | BioGRID | 3571333 |
| THBS1 | ITGB1 | - | HPRD | 11980922 |
| THBS1 | IGFBP5 | Reconstituted Complex | BioGRID | 10698186 |
| IGFBP-5 interacts with TS-1. | BIND | 15700281 | ||
| THBS1 | CTSG | - | HPRD | 8408036 |
| THBS1 | ITGB3 | Reconstituted Complex | BioGRID | 2478219 |
| THBS1 | KNG1 | - | HPRD | 9459346 |
| THBS1 | SPARC | - | HPRD | 2745554 |3402455 |
| THBS1 | PDGFB | - | HPRD,BioGRID | 9334164 |
| THBS1 | FN1 | - | HPRD | 11773026 |
| THBS1 | ELA2 | - | HPRD,BioGRID | 8463250 |
| THBS1 | CD47 | - | HPRD | 8550562 |9169439 |10397731 |
| IAP interacts with TS-1. This interaction was modeled on a demonstrated interaction between pig IAP and human TS-1. | BIND | 15700281 | ||
| THBS1 | PLG | - | HPRD,BioGRID | 2522013 |
| THBS1 | LRP1 | - | HPRD,BioGRID | 9045712 |14991768 |
| THBS1 | FGA | - | HPRD,BioGRID | 9867861 |
| THBS1 | CD47 | - | HPRD | 8550562 |9169439 |10397731 |
| IAP interacts with TS-1. This interaction was modeled on a demonstrated interaction between pig IAP and human TS-1. | BIND | 15700281 | ||
| THBS1 | CD36 | - | HPRD | 10487979 |10772961 |
| THBS1 | LRP5 | - | HPRD | 7775583 |
| THBS1 | LAMB3 | - | HPRD,BioGRID | 9840442 |
| THBS1 | COL2A1 | - | HPRD,BioGRID | 3571333 |
| THBS1 | DHFR | - | HPRD,BioGRID | 10749676 |
| THBS1 | CALCR | Reconstituted Complex | BioGRID | 12147682 |
| THBS1 | MMP9 | - | HPRD,BioGRID | 10900205 |
| THBS1 | TFPI | - | HPRD,BioGRID | 10922378 |
| THBS1 | SCARB2 | - | HPRD,BioGRID | 9478926 |
| THBS1 | COL5A1 | - | HPRD,BioGRID | 6693501 |9840442 |
| THBS1 | COL3A1 | - | HPRD,BioGRID | 3571333 |
| THBS1 | HRG | - | HPRD | 6438154 |
| SPOCK1 | MMP14 | - | HPRD | 12810672 |
| SPOCK1 | MMP3 | - | HPRD | 12810672 |
| CLDN1 | INADL | - | HPRD,BioGRID | 12021270 |
| CLDN1 | TJP3 | - | HPRD,BioGRID | 10601346 |
| CLDN1 | MPDZ | - | HPRD | 11689568 |
| CLDN1 | CLDN3 | - | HPRD,BioGRID | 10562289 |12909588 |
| CLDN1 | CLDN5 | Affinity Capture-Western | BioGRID | 12909588 |
| CLDN1 | TJP1 | - | HPRD,BioGRID | 10601346 |
| CLDN1 | TJP2 | - | HPRD,BioGRID | 10601346 |
| CLDN1 | MMP14 | - | HPRD | 11382769 |
| TIMP3 | ADAM17 | - | HPRD,BioGRID | 12044879 |
| TIMP3 | MMP9 | - | HPRD,BioGRID | 11827795 |
| TIMP3 | MMP14 | - | HPRD | 8663332 |
| TIMP3 | MMP13 | - | HPRD | 9065415 |
| TIMP3 | MMP3 | - | HPRD,BioGRID | 11827795 |
| BCAN | MMP3 | - | HPRD,BioGRID | 10986281 |
| BCAN | MMP13 | - | HPRD,BioGRID | 10986281 |
| BCAN | TNR | - | HPRD | 9294172 |
| BCAN | MMP7 | - | HPRD,BioGRID | 10986281 |
| BCAN | MMP1 | - | HPRD,BioGRID | 10986281 |
| BCAN | MMP8 | - | HPRD,BioGRID | 10986281 |
| BCAN | FBLN2 | - | HPRD,BioGRID | 11038354 |
| BCAN | MMP10 | - | HPRD,BioGRID | 10986281 |
| LCN2 | MMP9 | - | HPRD,BioGRID | 1281792 |10339412 |
| CXCL12 | CD4 | - | HPRD | 10600606 |
| CXCL12 | PF4 | Reconstituted Complex | BioGRID | 10233851 |
| CXCL12 | FN1 | - | HPRD,BioGRID | 11023498 |
| CXCL12 | CXCR4 | - | HPRD | 10233851 |
| CXCR4 interacts with SDF-1-alpha. This interaction was modeled on a demonstrated interaction between human CXCR4 and SDF-1-alpha from an unspecified species. | BIND | 15183061 | ||
| CXCL12 | CXCR4 | - | HPRD | 10233851 |
| CXCR4 interacts with SDF-1-alpha. This interaction was modeled on a demonstrated interaction between human CXCR4 and SDF-1-alpha from an unspecified species. | BIND | 15183061 | ||
| ITGAV | ITGB5 | Integrin-alphaV interacts with integrin-beta5. | BIND | 1694173 |
| ITGAV (alphaV) interacts with ITGB5 (beta5). | BIND | 12459484 | ||
| - | HPRD,BioGRID | 7689573 | ||
| ITGAV | ITGB3 | Integrin-alphaV interacts with Integrin-beta3. | BIND | 1693624 |2138612 |
| - | HPRD,BioGRID | 11884718 | ||
| ITGAV | ITGB3 | Integrin-alphaV interacts with Integrin-beta3. | BIND | 1693624 |2138612 |
| - | HPRD,BioGRID | 11884718 | ||
| ITGAV | L1CAM | - | HPRD,BioGRID | 10871287 |
| ITGAV | ITGB1 | Integrin-alphaV interacts with Integrin-beta1 | BIND | 1690718 |2138612 |
| ITGAV | F2R | - | HPRD | 11278329 |
| ITGAV | CD47 | - | HPRD | 10545994 |
| ITGAV | ITGB5 | Integrin-alphaV interacts with integrin-beta5. | BIND | 1694173 |
| ITGAV (alphaV) interacts with ITGB5 (beta5). | BIND | 12459484 | ||
| - | HPRD,BioGRID | 7689573 | ||
| ITGAV | ANGPTL3 | - | HPRD | 11877390 |
| ITGAV | ITGB5 | Integrin-alphaV interacts with integrin-beta5. | BIND | 1694173 |
| ITGAV (alphaV) interacts with ITGB5 (beta5). | BIND | 12459484 | ||
| - | HPRD,BioGRID | 7689573 | ||
| ITGAV | ITGB6 | Integrin-alphaV interacts with Integrin-beta6. | BIND | 8798654 |
| - | HPRD | 1532572 | ||
| ITGAV | PTK2 | - | HPRD | 11927607 |
| ITGAV | ITGB6 | Integrin-alphaV interacts with Integrin-beta6. | BIND | 8798654 |
| - | HPRD | 1532572 | ||
| ITGAV | SPP1 | - | HPRD | 10835423 |
| ITGAV | AZGP1 | - | HPRD | 9813179 |
| ITGAV | NOV | Reconstituted Complex | BioGRID | 12902636 |
| ITGAV | P2RY2 | - | HPRD,BioGRID | 11331301 |
| ITGAV | PDGFRA | - | HPRD | 11953315 |
| ITGAV | CYR61 | - | HPRD,BioGRID | 11287419 |
| ITGAV | ITGB8 | Integrin-alphaV interacts with Integrin-beta8. | BIND | 1918072 |
| - | HPRD | 1918072 | ||
| ITGAV | PAK4 | - | HPRD,BioGRID | 12356872 |
| ITGAV | AUP1 | - | HPRD,BioGRID | 12042322 |
| ITGAV | ITGB8 | Integrin-alphaV interacts with Integrin-beta8. | BIND | 1918072 |
| - | HPRD | 1918072 | ||
| ITGAV | ICAM4 | - | HPRD | 11435317 |
| A2M | CTSB | - | HPRD | 2476070 |
| A2M | HSPA5 | - | HPRD,BioGRID | 12194978 |
| A2M | IL4 | Reconstituted Complex | BioGRID | 10714547 |
| A2M | ADAMTS1 | - | HPRD,BioGRID | 10373500 |
| A2M | LCAT | - | HPRD,BioGRID | 11435418 |
| A2M | B2M | - | HPRD,BioGRID | 10731476 |
| A2M | IL10 | - | HPRD,BioGRID | 10714547 |
| A2M | PAEP | - | HPRD,BioGRID | 11023837 |
| A2M | LEP | - | HPRD,BioGRID | 9724081 |
| A2M | KLK3 | - | HPRD | 8583572 |
| Affinity Capture-Western | BioGRID | 1702714 | ||
| A2M | ELA1 | - | HPRD | 6153632 |6191979 |
| A2M | KLK13 | Reconstituted Complex | BioGRID | 14687906 |
| A2M | AMBP | - | HPRD,BioGRID | 1697852 |7519849 |7533162 |
| A2M | APOE | - | HPRD,BioGRID | 9831625 |
| A2M | IL1B | - | HPRD | 9714181 |
| A2M | KLK3 | - | HPRD | 8583572 |
| Affinity Capture-Western | BioGRID | 1702714 | ||
| A2M | CPB2 | Reconstituted Complex | BioGRID | 8662763 |
| A2M | NGF | - | HPRD,BioGRID | 10681572 |
| A2M | PDGFB | - | HPRD | 10681572 |
| A2M | STAT3 | An unspecified isoform of STAT3 binds APRE. | BIND | 15950906 |
| A2M | LRP1 | - | HPRD,BioGRID | 10652313 |
| A2M | ADAM19 | - | HPRD | 11162584 |
| THBS2 | THBS3 | - | HPRD | 1459996 |
| THBS2 | MMP9 | - | HPRD,BioGRID | 10900205 |
| COL7A1 | FN1 | - | HPRD,BioGRID | 7963647 |9169408 |
| COL7A1 | COL4A1 | - | HPRD,BioGRID | 9169408 |
| COL7A1 | LAMB3 | - | HPRD,BioGRID | 9989793 |
| COL7A1 | LAMA5 | - | HPRD,BioGRID | 9245798 |
| Collagen VII interacts with laminin 5. | BIND | 15774758 | ||
| COL7A1 | LAMC2 | - | HPRD,BioGRID | 9989793 |
| COL7A1 | LAMA5 | - | HPRD,BioGRID | 9245798 |
| Collagen VII interacts with laminin 5. | BIND | 15774758 | ||
| BACE1 | PDIA3 | BACE1 interacts with PDIA3 (ERp60). This interaction was modelled on a demonstrated interaction between mouse BACE1 and human PDIA3. | BIND | 15606899 |
| BACE1 | CMPK1 | BACE1 interacts with UMP-CMPK. This interaction was modelled on a demonstrated interaction between mouse BACE1 and human UMP-CMPK. | BIND | 15606899 |
| BACE1 | RANBP9 | BACE1 interacts with RANBP9 (RANBPM). This interaction was modelled on a demonstrated interaction between mouse BACE1 and human RANBPM. | BIND | 15606899 |
| BACE1 | GGA2 | - | HPRD | 12135764 |
| BACE1 | NCSTN | Nicastrin interacts with BACE1. | BIND | 12054507 |
| - | HPRD,BioGRID | 12054507 | ||
| BACE1 | KHSRP | BACE1 interacts with KHSRP. This interaction was modelled on a demonstrated interaction between mouse BACE1 and human KHSRP. | BIND | 15606899 |
| BACE1 | ITM2C | - | HPRD | 15606899 |
| BACE1 interacts with ITM2C (BRI3). | BIND | 15606899 | ||
| BACE1 | ITM2C | - | HPRD | 15606899 |
| BACE1 interacts with ITM2C (BRI3). | BIND | 15606899 | ||
| BACE1 | PSAP | BACE1 interacts with PSAP (prosaposin). This interaction was modelled on a demonstrated interaction between mouse BACE1 and human prosaposin. | BIND | 15606899 |
| BACE1 | NCSTN | Nicastrin interacts with BACE1. | BIND | 12054507 |
| - | HPRD,BioGRID | 12054507 | ||
| BACE1 | ATP1B1 | BACE1 interacts with ATP1B1 (Na/K-ATPase, beta-subunit). This interaction was modelled on a demonstrated interaction between mouse BACE1 and human Na/K-ATPase, beta-subunit. | BIND | 15606899 |
| PZP | CPB2 | - | HPRD | 8662763 |
| PZP | KLK3 | - | HPRD | 1702714 |
| PZP | TGFB2 | - | HPRD,BioGRID | 7513640 |
| PZP | MMP9 | - | HPRD | 9344465 |
| COL18A1 | FBLN2 | - | HPRD | 10544250 |
| COL18A1 | KDR | - | HPRD,BioGRID | 12029087 |
| COL18A1 | GPC1 | - | HPRD,BioGRID | 11336704 |
| COL18A1 | ITGA5 | - | HPRD | 11158588 |
| COL18A1 | CTSL1 | - | HPRD | 10716919 |
| COL18A1 | GPC4 | - | HPRD,BioGRID | 11336704 |
| MMP17 | LRP1 | - | HPRD | 14645246 |
| TIMP2 | SNCG | Affinity Capture-MS | BioGRID | 17353931 |
| TIMP2 | PSMA7 | Affinity Capture-MS | BioGRID | 17353931 |
| TIMP2 | MMP8 | - | HPRD,BioGRID | 10353844 |
| TIMP2 | MMP14 | - | HPRD,BioGRID | 9422789 |
| TIMP2 | ITGA3 | TIMP2 interacts with ITGA3 (alpha3). | BIND | 12887919 |
| CCL7 | CCR2 | - | HPRD,BioGRID | 8530354 |
| CCL7 | CCR1 | - | HPRD,BioGRID | 8530354 |
| CCL7 | FEZ1 | Two-hybrid | BioGRID | 16169070 |
| CCL7 | CCR10 | - | HPRD | 9364936 |
| CCL7 | CCR3 | - | HPRD,BioGRID | 8642344 |
| CCL7 | CCBP2 | - | HPRD,BioGRID | 9364936 |9405404 |
| CCL7 | CCR5 | - | HPRD | 10477718 |
| TGFB1 | YWHAE | - | HPRD,BioGRID | 11172812 |
| TGFB1 | MMP9 | Biochemical Activity | BioGRID | 10652271 |
| TGFB1 | TGFBR2 | Affinity Capture-Western | BioGRID | 11157754 |
| - | HPRD | 7935686 | ||
| TGF-beta-1 interacts with TGF-beta-R-II. This interaction was modeled on a demonstrated interaction between TGF-beta-1 from an unspecified species and human TGF-beta-R-II. | BIND | 7852346 | ||
| TGFB1 | FCN1 | - | HPRD,BioGRID | 7686157 |
| TGFB1 | CCL3 | - | HPRD | 8568261 |
| TGFB1 | EIF3I | - | HPRD,BioGRID | 9813058 |
| TGFB1 | TGFB2 | Two-hybrid | BioGRID | 11483955 |
| - | HPRD | 11157754 | ||
| TGFB1 | VASN | - | HPRD,BioGRID | 15247411 |
| TGFB1 | DCN | - | HPRD | 7638106 |7798269 |
| Reconstituted Complex | BioGRID | 7798269 |8093006 |9675033 | ||
| TGFB1 | VTN | - | HPRD,BioGRID | 11796824 |
| TGFB1 | CTGF | - | HPRD,BioGRID | 10457363 |
| TGFB1 | TGFBR2 | Affinity Capture-Western | BioGRID | 11157754 |
| - | HPRD | 7935686 | ||
| TGF-beta-1 interacts with TGF-beta-R-II. This interaction was modeled on a demonstrated interaction between TGF-beta-1 from an unspecified species and human TGF-beta-R-II. | BIND | 7852346 | ||
| TGFB1 | ENG | - | HPRD | 12015308 |
| TGFB1 | COL2A1 | - | HPRD,BioGRID | 10085302 |
| TGFB1 | BMP3 | - | HPRD | 9434787 |
| TGFB1 | ACVRL1 | - | HPRD,BioGRID | 10716993 |
| TGFB1 | APP | TGF-beta-1 interacts with Amyloid-beta. This interaction was modelled on a demonstrated interaction between TGF-beta-1 from an unspecified species and consensus Amyloid-beta peptides. | BIND | 12867422 |
| TGFB1 | LTBP4 | - | HPRD | 9660815 |
| TGFB1 | LTBP1 | - | HPRD,BioGRID | 8617200 |10930463 |
| TGFB1 | TGFBR1 | TGF-beta-1 interacts with TGF-beta-R-I. This interaction was modeled on a demonstrated interaction between TGF-beta-1 from an unspecified species and human TGF-beta-R-I. | BIND | 7852346 |
| - | HPRD,BioGRID | 8235612 | ||
| TGFB1 | BGN | - | HPRD,BioGRID | 8093006 |10383378 |
| TGFB1 | TGFBR2 | Affinity Capture-Western | BioGRID | 11157754 |
| - | HPRD | 7935686 | ||
| TGF-beta-1 interacts with TGF-beta-R-II. This interaction was modeled on a demonstrated interaction between TGF-beta-1 from an unspecified species and human TGF-beta-R-II. | BIND | 7852346 | ||
| TGFB1 | DAXX | - | HPRD | 11483955 |
| TGFB1 | BMP2 | - | HPRD | 11456401 |
| TGFB1 | TGFB2 | Two-hybrid | BioGRID | 11483955 |
| - | HPRD | 11157754 | ||
| TGFB1 | FNTA | - | HPRD,BioGRID | 8599089 |
| TGFB1 | ITGB8 | - | HPRD | 11970960 |
| TGFB1 | DCN | - | HPRD | 7638106 |7798269 |
| Reconstituted Complex | BioGRID | 7798269 |8093006 |9675033 | ||
| TGFB1 | FMOD | - | HPRD,BioGRID | 8093006 |
| TGFB1 | SNIP1 | Affinity Capture-Western | BioGRID | 10887155 |
| TGFB1 | TGFBR3 | - | HPRD | 7935686 |
| Affinity Capture-Western | BioGRID | 8106553 | ||
| TGFB1 | SPARC | - | HPRD | 15034927 |
| TGFB1 | TGFBRAP1 | Affinity Capture-Western | BioGRID | 11278302 |
| TGFB1 | ITGB6 | - | HPRD | 10025398 |
| TGFB1 | LTBP3 | - | HPRD | 12062452 |
| TGFB1 | TGFBR1 | TGF-beta-1 interacts with TGF-beta-R-I. This interaction was modeled on a demonstrated interaction between TGF-beta-1 from an unspecified species and human TGF-beta-R-I. | BIND | 7852346 |
| - | HPRD,BioGRID | 8235612 | ||
| TGFB1 | TGFBR3 | - | HPRD | 7935686 |
| Affinity Capture-Western | BioGRID | 8106553 | ||
| COL1A1 | ITGA5 | - | HPRD | 1693626 |
| COL1A1 | IGFBP3 | - | HPRD,BioGRID | 12735930 |
| COL1A1 | SPARC | - | HPRD | 7034958 |
| Reconstituted Complex | BioGRID | 2745554 | ||
| COL1A1 | PAK1 | - | HPRD,BioGRID | 10772928 |
| COL1A1 | TGFBI | - | HPRD,BioGRID | 11867580 |12034705 |
| COL1A1 | ITGB1 | Co-purification | BioGRID | 2156854 |
| COL1A1 | PDGFB | - | HPRD | 10446987 |
| COL1A1 | DCN | - | HPRD | 1468447 |9675033 |
| COL1A1 | MAG | Reconstituted Complex | BioGRID | 2446864 |
| COL1A1 | CAPN1 | CAPN1 interacts with COL1A1. | BIND | 12358155 |
| COL1A1 | VWF | - | HPRD,BioGRID | 3490481 |
| COL1A1 | CD44 | - | HPRD | 1730778 |
| COL1A1 | DDR2 | - | HPRD,BioGRID | 9659899 |
| COL1A1 | FN1 | - | HPRD,BioGRID | 8468356 |
| COL1A1 | TMPRSS6 | - | HPRD,BioGRID | 12149247 |
| COL1A1 | PKD1 | Reconstituted Complex | BioGRID | 11752017 |
| COL1A1 | SPARC | - | HPRD | 7034958 |
| Reconstituted Complex | BioGRID | 2745554 | ||
| COL1A1 | P4HB | - | HPRD | 1339453 |
| COL1A1 | NID2 | Reconstituted Complex | BioGRID | 9733643 |
| COL1A1 | ITGA2 | Co-purification; in vitro; in vivo | BioGRID | 2156854 |11359786 |11856343 |
| - | HPRD | 2156854|11359786 |11856343 | ||
| COL1A1 | MMP9 | - | HPRD,BioGRID | 9878537 |
| COL1A1 | PRELP | - | HPRD,BioGRID | 11847210 |
| COL1A1 | ITGA2 | Co-purification; in vitro; in vivo | BioGRID | 2156854 |11359786 |11856343 |
| - | HPRD | 2156854|11359786 |11856343 | ||
| COL1A1 | CD93 | - | HPRD | 1377218 |
| COL1A1 | TXN | Reconstituted Complex; Two-hybrid | BioGRID | 12099690 |
| COL1A1 | BGN | - | HPRD | 7852349 |
| COL1A1 | CD36 | - | HPRD,BioGRID | 2468670 |
| COL1A1 | MATN2 | - | HPRD,BioGRID | 12180907 |
| COL1A1 | FGF7 | in vitro | BioGRID | 11973338 |
| COL1A1 | NID1 | - | HPRD,BioGRID | 9733643 |
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