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Protein-protein interaction for DDR2
 Nodes,
degree=1 |
 Nodes,
degree=2 |
Protein-protein interaction data for gene DDR2
| Degree = 1 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| DDR2 | SRC | - | HPRD,BioGRID | 11884411 |
| DDR2 | SHC1 | - | HPRD,BioGRID | 11884411 |
| DDR2 | COL1A1 | - | HPRD,BioGRID | 9659899 |
| DDR2 | COL3A1 | - | HPRD,BioGRID | 9659899 |
| Degree = 2 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| SRC | GAB3 | - | HPRD,BioGRID | 11739737 |
| SRC | ASAP1 | - | HPRD,BioGRID | 9819391 |
| SRC | WBP11 | - | HPRD | 11375989 |
| SRC | PIK3R1 | - | HPRD | 12210743 |
| Affinity Capture-Western | BioGRID | 10487518 | ||
| SRC | STAT3 | - | HPRD,BioGRID | 8657134 |
| SRC | SRF | - | HPRD,BioGRID | 9786846 |
| SRC | TNFSF11 | Affinity Capture-Western | BioGRID | 10635328 |
| SRC | MAPK8IP3 | Biochemical Activity | BioGRID | 12226752 |
| SRC | MST1R | - | HPRD | 8918464 |
| SRC | RICS | - | HPRD,BioGRID | 12454018 |
| Src interacts with GC-GAP. This interaction was modelled on a demonstrated interaction between Src from an unspecified species and human GC-GAP. | BIND | 12819203 | ||
| SRC | PTPN2 | PTPN2 (TCPTP) interacts with Src. This interaction was modelled on a demonstrated interaction between human PTPN2 and chicken Src. | BIND | 15696169 |
| SRC | ADRB2 | Affinity Capture-Western | BioGRID | 11013230 |
| SRC | IL6R | - | HPRD | 10462375 |
| SRC | TRAF3 | Affinity Capture-Western | BioGRID | 10635328 |
| SRC | SHB | Shb interacts with Src. This interaction was modelled on a demonstrated interaction between human Shb and chicken Src. | BIND | 7537362 |
| - | HPRD,BioGRID | 7537362 | ||
| SRC | RXRA | Reconstituted Complex | BioGRID | 10517671 |
| SRC | SH3BP1 | - | HPRD,BioGRID | 1379745 |
| SRC | CD44 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 11084024 |
| SRC | BMX | - | HPRD,BioGRID | 10688651 |
| SRC | STAT5A | - | HPRD | 10358079 |
| SRC | ERBB2 | - | HPRD | 7542762 |
| Reconstituted Complex | BioGRID | 11940572 | ||
| SRC (SRC-1) interacts with the ERBB2 (HER2) promoter. | BIND | 15788656 | ||
| SRC | RARA | Reconstituted Complex | BioGRID | 10454579 |
| SRC | GSN | Affinity Capture-Western | BioGRID | 11577104 |
| SRC | CD36 | - | HPRD | 7521304 |
| SRC | ESR1 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 10454579 |11032808 |11564893 |
| SRC | AR | Affinity Capture-Western; Two-hybrid | BioGRID | 11032808 |15027889 |15466214 |
| SRC | DAB2 | - | HPRD,BioGRID | 12473651 |
| SRC | ABL1 | c-Abl interacts with Src. This interaction was modeled on a demonstrated interaction between human c-Abl and v-Src from the Rous Sarcoma virus. | BIND | 1383690 |
| SRC | SMARCE1 | - | HPRD | 12145209 |
| SRC | PDE4D | PDE4D4 interacts with Src SH3 domain. | BIND | 10571082 |
| SRC | HNF1A | - | HPRD,BioGRID | 10777539 |
| SRC | CD2AP | - | HPRD | 10339567 |
| SRC | NCOA6 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 10567404 |10847592 |11158331 |12482968 |
| SRC | CSK | - | HPRD,BioGRID | 7513429 |
| SRC | PTK2 | c-Src interacts with FAK. This interaction was modeled on a demonstrated interaction between human c-Src and mouse FAK. | BIND | 9148935 |
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 10085298 |11980671 |12387730 |12558988 |12615911 | ||
| - | HPRD | 7529876 |8054685 |10931187 | ||
| - | HPRD | 7529876 |8054685 | ||
| Src interacts with tyrosine autophosphorylated FAK. This interaction was modeled on a demonstrated interaction between human Src and avian FAK. | BIND | 7515480 | ||
| SRC | SYN1 | - | HPRD,BioGRID | 10899172 |
| SRC | MICAL1 | Reconstituted Complex | BioGRID | 11827972 |
| SRC | MPZL1 | - | HPRD,BioGRID | 11751924 |
| SRC | CDCP1 | Src interacts with CDCP1. This interaction was modelled on a demonstrated interaction between Src from an unspecified species and human CDCP1. | BIND | 15851033 |
| SRC | SH3PXD2A | - | HPRD | 9687503 |
| SRC | PRKCE | - | HPRD | 11834516 |
| SRC | CBL | - | HPRD | 8635998 |
| Cbl interacts with Src. This interaction was modeled on a demonstrated interaction between human Cbl and Src from unspecified species. | BIND | 15135048 | ||
| SRC | PTK2 | c-Src interacts with FAK. This interaction was modeled on a demonstrated interaction between human c-Src and mouse FAK. | BIND | 9148935 |
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 10085298 |11980671 |12387730 |12558988 |12615911 | ||
| - | HPRD | 7529876 |8054685 |10931187 | ||
| - | HPRD | 7529876 |8054685 | ||
| Src interacts with tyrosine autophosphorylated FAK. This interaction was modeled on a demonstrated interaction between human Src and avian FAK. | BIND | 7515480 | ||
| SRC | RICS | - | HPRD,BioGRID | 12454018 |
| Src interacts with GC-GAP. This interaction was modelled on a demonstrated interaction between Src from an unspecified species and human GC-GAP. | BIND | 12819203 | ||
| SRC | PXN | Reconstituted Complex | BioGRID | 10085298 |
| - | HPRD | 7534286 | ||
| SRC | NPHS1 | - | HPRD | 12846735 |
| SRC | GRB2 | - | HPRD,BioGRID | 11964172 |
| SRC | LRP1 | Biochemical Activity | BioGRID | 11854294 |
| SRC | DOK4 | - | HPRD | 12730241 |
| IRS5/DOK4 interacts with Src. This interaction was modelled on a demonstrated interaction between human IRS5/DOK4 and hamster Src. | BIND | 12730241 | ||
| SRC | SLC9A2 | - | HPRD,BioGRID | 10187839 |
| SRC | RASA1 | - | HPRD,BioGRID | 1717825 |
| SRC | PTK2 | c-Src interacts with FAK. This interaction was modeled on a demonstrated interaction between human c-Src and mouse FAK. | BIND | 9148935 |
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 10085298 |11980671 |12387730 |12558988 |12615911 | ||
| - | HPRD | 7529876 |8054685 |10931187 | ||
| - | HPRD | 7529876 |8054685 | ||
| Src interacts with tyrosine autophosphorylated FAK. This interaction was modeled on a demonstrated interaction between human Src and avian FAK. | BIND | 7515480 | ||
| SRC | RPS6KB1 | Biochemical Activity | BioGRID | 16640565 |
| SRC | EP300 | Reconstituted Complex | BioGRID | 10973497 |
| SRC | PLD2 | Affinity Capture-Western; Biochemical Activity; Reconstituted Complex | BioGRID | 12697812 |
| SRC | ADRBK1 | - | HPRD,BioGRID | 12624098 |
| SRC | ADRB3 | - | HPRD,BioGRID | 11013230 |
| SRC | EPS8 | - | HPRD,BioGRID | 10395945 |
| SRC | CD59 | - | HPRD | 12219031 |
| SRC | MUC1 | MUC1 interacts with c-Src. | BIND | 11483589 |
| - | HPRD,BioGRID | 11152665 |11483589 | ||
| SRC | ADAM12 | - | HPRD | 11127814 |
| SRC | ETS2 | SRC (SRC-1) interacts with ETS2. | BIND | 15788656 |
| SRC | CSF1R | Affinity Capture-Western | BioGRID | 7681396 |
| SRC | SNURF | Phenotypic Enhancement | BioGRID | 11696545 |
| SRC | KHDRBS1 | - | HPRD,BioGRID | 1545818 |8766817 |10467411 |
| c-Src SH3 domain interacts with Sam68 proline-rich region. This interaction was modelled on a demonstrated interaction between c-Src from an unspecified source and human Sam68. | BIND | 7537265 | ||
| SRC | ADAM15 | - | HPRD | 11741929 |
| SRC | GJA1 | - | HPRD | 9278444 |
| Cx43 interacts with v-Src. This interaction was modelled on a demonstrated interaction between rat Cx43 and human v-Src. | BIND | 9278444 | ||
| SRC | YWHAH | - | HPRD | 8702721 |
| SRC | MET | - | HPRD,BioGRID | 9837958 |
| SRC | CDH1 | Affinity Capture-Western | BioGRID | 10744074 |
| SRC | GRIN2A | Affinity Capture-Western; Reconstituted Complex | BioGRID | 10458595 |12932824 |
| - | HPRD | 10458595 |10884433 |12932824 | ||
| SRC | HNRNPK | Src interacts with hnRNPK. This interaction was modeled on a demonstrated interaction between Src from an unspecified source and human hnRNPK. | BIND | 8810341 |
| SRC | PTK2B | - | HPRD | 8849729 |10777553 |
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 8849729 |10521452 |10777553 | ||
| SRC | SKAP1 | - | HPRD,BioGRID | 9195899 |
| SRC | PRKCZ | - | HPRD,BioGRID | 10527887 |
| SRC | PXN | Reconstituted Complex | BioGRID | 10085298 |
| - | HPRD | 7534286 | ||
| SRC | STAT1 | - | HPRD,BioGRID | 9344858 |
| SRC | KCNQ5 | - | HPRD | 15304482 |
| SRC | PKD1 | - | HPRD | 11113628 |
| SRC | ERBB2 | - | HPRD | 7542762 |
| Reconstituted Complex | BioGRID | 11940572 | ||
| SRC (SRC-1) interacts with the ERBB2 (HER2) promoter. | BIND | 15788656 | ||
| SRC | DTNA | - | HPRD | 9701558 |
| SRC | CBL | - | HPRD | 8635998 |
| Cbl interacts with Src. This interaction was modeled on a demonstrated interaction between human Cbl and Src from unspecified species. | BIND | 15135048 | ||
| SRC | ARHGAP1 | - | HPRD,BioGRID | 8253717 |
| SRC | GRIN2A | Affinity Capture-Western; Reconstituted Complex | BioGRID | 10458595 |12932824 |
| - | HPRD | 10458595 |10884433 |12932824 | ||
| SRC | DAG1 | Affinity Capture-Western; Biochemical Activity; Reconstituted Complex | BioGRID | 11724572 |
| SRC | YWHAE | - | HPRD | 8702721 |
| SRC | CEACAM3 | - | HPRD | 11708798 |
| SRC | MAPK15 | - | HPRD | 11875070 |
| SRC | PDE6G | - | HPRD,BioGRID | 12624098 |
| SRC | ARHGAP17 | Reconstituted Complex | BioGRID | 11431473 |
| SRC | CAV2 | Reconstituted Complex | BioGRID | 12091389 |
| SRC | RET | - | HPRD,BioGRID | 10070972 |
| SRC | E2F4 | E2F4 interacts with SRC enhancer. | BIND | 15782160 |
| SRC | BCAR1 | c-Src interacts with CAS. | BIND | 9148935 |
| Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 10085298 |10487518 |10739664 |11514617 |12397603 |12615911 | ||
| SRC | RAF1 | - | HPRD,BioGRID | 7517401 |
| SRC | TRPV4 | - | HPRD,BioGRID | 12538589 |
| SRC | PTK2 | c-Src interacts with FAK. This interaction was modeled on a demonstrated interaction between human c-Src and mouse FAK. | BIND | 9148935 |
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 10085298 |11980671 |12387730 |12558988 |12615911 | ||
| - | HPRD | 7529876 |8054685 |10931187 | ||
| - | HPRD | 7529876 |8054685 | ||
| Src interacts with tyrosine autophosphorylated FAK. This interaction was modeled on a demonstrated interaction between human Src and avian FAK. | BIND | 7515480 | ||
| SRC | MATK | - | HPRD,BioGRID | 7530249 |
| SRC | TRAF1 | Affinity Capture-Western | BioGRID | 10635328 |
| SRC | MAP2 | Reconstituted Complex | BioGRID | 10781592 |
| SRC | BCR | BCR interacts with Src. This interaction was modeled on a demonstrated interaction between BCR from an unspecified source and Src from Rous Sarcoma virus. | BIND | 1383690 |
| SRC | GIT1 | - | HPRD | 14523024 |
| SRC | KIFAP3 | - | HPRD,BioGRID | 8900189 |
| SRC | FARP2 | - | HPRD | 12771149 |
| SRC | PTK2 | c-Src interacts with FAK. This interaction was modeled on a demonstrated interaction between human c-Src and mouse FAK. | BIND | 9148935 |
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 10085298 |11980671 |12387730 |12558988 |12615911 | ||
| - | HPRD | 7529876 |8054685 |10931187 | ||
| - | HPRD | 7529876 |8054685 | ||
| Src interacts with tyrosine autophosphorylated FAK. This interaction was modeled on a demonstrated interaction between human Src and avian FAK. | BIND | 7515480 | ||
| SRC | EPHB2 | - | HPRD,BioGRID | 9632142 |
| SRC | PELP1 | Affinity Capture-Western | BioGRID | 15466214 |
| SRC | PDGFRB | PDGFR interacts with Src. This interaction was modelled on a demonstrated interaction between rat PDGFR and Src from an unknown species. | BIND | 2173144 |
| SRC | GJB1 | GJB1 (connexin32) interacts with and prevents the activation of Src. | BIND | 15782139 |
| SRC | ANKRD11 | - | HPRD | 15184363 |
| SRC | SHB | Shb interacts with Src. This interaction was modelled on a demonstrated interaction between human Shb and chicken Src. | BIND | 7537362 |
| - | HPRD,BioGRID | 7537362 | ||
| SRC | YWHAG | - | HPRD | 8702721 |
| SRC | EGFR | - | HPRD,BioGRID | 10971656 |
| SRC | AHR | Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 12024042 |
| SRC | PECAM1 | - | HPRD,BioGRID | 10858437 |
| SRC | FYN | Protein-peptide | BioGRID | 9169421 |
| SRC | PLSCR1 | Biochemical Activity | BioGRID | 12871937 |
| SRC | TIAM1 | - | HPRD | 12810717 |
| SRC | TRIP4 | Affinity Capture-Western | BioGRID | 10454579 |
| SRC | GAB2 | - | HPRD,BioGRID | 10391903 |
| SRC | FOXO1 | - | HPRD,BioGRID | 10973497 |
| SRC | HSP90AA1 | - | HPRD,BioGRID | 1310678 |
| SRC | EVL | - | HPRD,BioGRID | 10945997 |
| SRC | PTPRA | Affinity Capture-Western | BioGRID | 11923305 |
| SRC | ETS1 | SRC (SRC-1) interacts with ETS1. | BIND | 15788656 |
| SRC | ERBB2 | - | HPRD | 7542762 |
| Reconstituted Complex | BioGRID | 11940572 | ||
| SRC (SRC-1) interacts with the ERBB2 (HER2) promoter. | BIND | 15788656 | ||
| SRC | ESR2 | Affinity Capture-Western | BioGRID | 11032808 |
| SRC | TRIP6 | - | HPRD,BioGRID | 14688263 |
| SRC | GNB2L1 | - | HPRD,BioGRID | 9584165 |
| SRC | AXL | - | HPRD,BioGRID | 9178760 |
| SRC | ITK | Reconstituted Complex | BioGRID | 10636929 |
| SRC | RPS6KB2 | Biochemical Activity | BioGRID | 16640565 |
| SRC | PTPN21 | - | HPRD,BioGRID | 7519780 |
| SRC | AFAP1 | - | HPRD,BioGRID | 9655255 |
| SRC | CAV1 | - | HPRD,BioGRID | 8910575 |
| SRC | TRPC6 | - | HPRD,BioGRID | 14761972 |
| SRC | PLD1 | Biochemical Activity | BioGRID | 12697812 |
| SRC | GFAP | - | HPRD | 11379820 |
| SRC | RGS16 | SRC phosphorylates RGS16. This interaction was modeled on a demonstrated interaction between SRC from an unspecified species and human RSG16. | BIND | 12588871 |
| SRC | TRAF6 | - | HPRD,BioGRID | 10635328 |
| SRC | PIK3R1 | - | HPRD | 12210743 |
| Affinity Capture-Western | BioGRID | 10487518 | ||
| SRC | ANXA2 | - | HPRD,BioGRID | 11106497 |
| SRC | LYN | Protein-peptide | BioGRID | 9169421 |
| SRC | YTHDC1 | - | HPRD | 15175272 |
| SRC | EFNB1 | - | HPRD,BioGRID | 8878483 |
| SRC | SMARCB1 | - | HPRD | 12145209 |
| SRC | CD46 | - | HPRD,BioGRID | 10657632 |
| SRC | CRK | Affinity Capture-Western | BioGRID | 12615911 |
| SRC | GJA1 | - | HPRD | 9278444 |
| Cx43 interacts with v-Src. This interaction was modelled on a demonstrated interaction between rat Cx43 and human v-Src. | BIND | 9278444 | ||
| SRC | MUC1 | MUC1 interacts with c-Src. | BIND | 11483589 |
| - | HPRD,BioGRID | 11152665 |11483589 | ||
| SRC | WAS | - | HPRD,BioGRID | 8805332 |
| SRC | ARR3 | - | HPRD,BioGRID | 11877451 |
| SRC | MYLK | - | HPRD,BioGRID | 10362724 |
| SRC | ARNT | Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 12024042 |
| SRC | GRB10 | Biochemical Activity | BioGRID | 10871840 |
| SRC | DOK1 | Reconstituted Complex | BioGRID | 11071635 |
| SRC | BCAR1 | c-Src interacts with CAS. | BIND | 9148935 |
| Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 10085298 |10487518 |10739664 |11514617 |12397603 |12615911 | ||
| SRC | THRB | Reconstituted Complex | BioGRID | 10454579 |
| SRC | ND2 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 15069201 |
| SRC | TYRO3 | - | HPRD,BioGRID | 7537495 |
| SRC | CDC37 | Reconstituted Complex | BioGRID | 11085988 |
| SRC | PTK2B | - | HPRD | 8849729 |10777553 |
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 8849729 |10521452 |10777553 | ||
| SRC | SYK | - | HPRD,BioGRID | 7513017 |
| SRC | DOCK1 | Affinity Capture-Western | BioGRID | 12615911 |
| SRC | ASAP2 | Affinity Capture-Western | BioGRID | 10022920 |
| SRC | TUB | - | HPRD | 10455176 |
| SRC | CTNND1 | Affinity Capture-Western | BioGRID | 12640114 |
| SRC | PLCG1 | - | HPRD,BioGRID | 7510703 |
| SRC | DOK4 | - | HPRD | 12730241 |
| IRS5/DOK4 interacts with Src. This interaction was modelled on a demonstrated interaction between human IRS5/DOK4 and hamster Src. | BIND | 12730241 | ||
| SRC | KHDRBS1 | - | HPRD,BioGRID | 1545818 |8766817 |10467411 |
| c-Src SH3 domain interacts with Sam68 proline-rich region. This interaction was modelled on a demonstrated interaction between c-Src from an unspecified source and human Sam68. | BIND | 7537265 | ||
| SRC | RPL10 | Reconstituted Complex | BioGRID | 12138090 |
| SRC | YWHAB | - | HPRD | 8702721 |
| SRC | DRD4 | D4.4 interacts with c-Src. This interaction was modeled on a demonstrated interaction between human D4.4 and chicken c-Src. | BIND | 9843378 |
| SRC | FASLG | - | HPRD | 11741599 |
| SRC | GRIN2B | - | HPRD | 10884433 |
| SHC1 | CD22 | - | HPRD,BioGRID | 10748054 |
| SHC1 | STAT5A | Affinity Capture-Western | BioGRID | 10996427 |
| SHC1 | IL2RG | - | HPRD,BioGRID | 8643566 |
| SHC1 | DOK1 | Affinity Capture-Western | BioGRID | 10822173 |
| SHC1 | SP1 | - | HPRD | 7933095 |
| SHC1 | AXL | ShcA interacts with Axl. | BIND | 8610109 |
| SHC1 | NTRK2 | Reconstituted Complex | BioGRID | 10092678 |
| SHC1 | SOS1 | Affinity Capture-Western | BioGRID | 9344843 |10570290 |10675333 |10783152 |
| SHC1 | FLT4 | - | HPRD | 7675451 |8662748 |9927207 |
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 7970715 |8662748 |9927207 | ||
| SHC1 | PLCG2 | - | HPRD,BioGRID | 10623845 |
| SHC1 | MET | - | HPRD | 7731718 |
| Affinity Capture-Western | BioGRID | 9660480 | ||
| SHC1 | ERBB2 | - | HPRD,BioGRID | 9710588 |
| SHC1 | PDGFRB | PDGFR interacts with p52Shc | BIND | 8195171 |
| PDGFR interacts with p66Shc. | BIND | 8195171 | ||
| - | HPRD,BioGRID | 8195171 | ||
| Autophosphorylated PDGFR interacts with SHC. This interaction was modelled on a demonstrated interaction between human PDGFR and SHC from an unspecified species. | BIND | 8890167 | ||
| SHC1 | LRP1 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 11854294 |12789267 |
| - | HPRD | 12069755 |12789267 | ||
| SHC1 | DDR1 | - | HPRD | 10783152 |
| DDR1 interacts with Shc. | BIND | 9659899 |10681566 | ||
| SHC1 | EPHA2 | - | HPRD,BioGRID | 12400011 |
| SHC1 | RET | RET9 phosphorylates Shc. | BIND | 9047383 |
| - | HPRD,BioGRID | 8183561 |9047384 | ||
| SHC1 | CD3E | - | HPRD | 11855827 |
| SHC1 | ITGB3 | Integrin-beta-3 interacts with Shc. | BIND | 10964917 |
| SHC1 | NTRK1 | Shc interacts with Trk. This interaction was modelled on a demonstrated interaction between SHC from rat or mouse and Trk from human. | BIND | 8155326 |
| Shc interacts with NGFR. | BIND | 8577769 | ||
| ShcA interacts with TrkA. | BIND | 7542991 |8610109 |8943228 | ||
| Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 8183561 |9856458 |10092678 |10708759 |12446789 | ||
| SHC1 | IGF1R | IGFIR interacts with SHC. | BIND | 7541045 |
| - | HPRD,BioGRID | 8776723 | ||
| SHC1 | GRAP2 | - | HPRD | 9872323 |
| SHC1 | FLT3 | - | HPRD | 11027663 |
| SHC1 | PIK3R1 | Reconstituted Complex | BioGRID | 7537361 |
| p85 interacts with Shc. | BIND | 8662998 | ||
| - | HPRD | 8662998 | ||
| SHC1 | GRB2 | Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Reconstituted Complex | BioGRID | 7514169 |7524086 |7535773 |8112292 |8195171 |8294403 |8491186 |8647288 |8662733 |9045692 |9083103 |9927207 |10080542 |10477741 |10570290 |11302736 |11505033 |11964172 |12441060 |12577067 |
| Shc interacts with Grb2. This interaction was modelled on a demonstrated interaction between Shc from human and Grb2 from rat and an unspecified species. | BIND | 8084588 | ||
| - | HPRD | 7524086 |7535773 |8491186 |11707405 | ||
| An unspecified isoform of Grb2 interacts with the p52 isoform of Shc. | BIND | 9148935 | ||
| Grb2 interacts with Shc. | BIND | 7515480 |8112292 |8939605 |10891441 | ||
| SHC1 | EGFR | Shc interacts with activated EGFR. | BIND | 1623525 |
| ShcA interacts with EGFR. | BIND | 8610109 | ||
| ShcA interacts with the EGFR. | BIND | 8577769 |8610109 |8943228 | ||
| - | HPRD,BioGRID | 9544989 | ||
| EGF-R interacts with Shc. This interaction was modelled on a demonstrated interaction between human EGF-R and mouse Shc. | BIND | 8887653 | ||
| SHC1 | IL2 | - | HPRD | 10662798 |
| SHC1 | ALK | Affinity Capture-Western | BioGRID | 11888936 |
| - | HPRD | 9174053 | ||
| SHC1 | STAT5B | Affinity Capture-Western | BioGRID | 10996427 |
| SHC1 | CSF2RB | - | HPRD,BioGRID | 10477722 |10704825 |
| SHC1 | ERBB4 | Affinity Capture-MS | BioGRID | 16729043 |
| SHC1 | PLCG1 | Affinity Capture-Western | BioGRID | 8662733 |
| SHC1 | PPP2R5A | - | HPRD | 11884620 |
| SHC1 | IL2RB | - | HPRD,BioGRID | 8294403 |10602027 |
| SHC1 | MME | - | HPRD,BioGRID | 9659899 |
| SHC1 | ERBB3 | - | HPRD | 9694850 |
| Affinity Capture-MS | BioGRID | 16729043 | ||
| SHC1 | INPP5D | - | HPRD | 8643691 |8723348 |8874179 |
| Affinity Capture-Western | BioGRID | 8643691 |10194451 |10822173 |10900203 |12024011 | ||
| SHC interacts with SHIP1 | BIND | 10822173 | ||
| SHC1 | APP | - | HPRD,BioGRID | 9045663 |11877420 |
| SHC1 | JAK2 | - | HPRD,BioGRID | 7535773 |9126968 |
| SHC1 | AP2A1 | - | HPRD | 8617812 |11302736 |
| SHC1 | CDH5 | - | HPRD,BioGRID | 11950700 |
| SHC1 | PIK3R2 | - | HPRD | 8662998 |
| SHC1 | GRB2 | Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Reconstituted Complex | BioGRID | 7514169 |7524086 |7535773 |8112292 |8195171 |8294403 |8491186 |8647288 |8662733 |9045692 |9083103 |9927207 |10080542 |10477741 |10570290 |11302736 |11505033 |11964172 |12441060 |12577067 |
| Shc interacts with Grb2. This interaction was modelled on a demonstrated interaction between Shc from human and Grb2 from rat and an unspecified species. | BIND | 8084588 | ||
| - | HPRD | 7524086 |7535773 |8491186 |11707405 | ||
| An unspecified isoform of Grb2 interacts with the p52 isoform of Shc. | BIND | 9148935 | ||
| Grb2 interacts with Shc. | BIND | 7515480 |8112292 |8939605 |10891441 | ||
| SHC1 | GH1 | Biochemical Activity | BioGRID | 7535773 |
| SHC1 | NTRK3 | - | HPRD | 7657612 |
| Reconstituted Complex | BioGRID | 10092678 | ||
| SHC1 | INPP5D | - | HPRD | 8643691 |8723348 |8874179 |
| Affinity Capture-Western | BioGRID | 8643691 |10194451 |10822173 |10900203 |12024011 | ||
| SHC interacts with SHIP1 | BIND | 10822173 | ||
| SHC1 | PAG1 | - | HPRD,BioGRID | 10790433 |
| SHC1 | PTK2B | - | HPRD | 7544443 |
| SHC1 | LRP1 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 11854294 |12789267 |
| - | HPRD | 12069755 |12789267 | ||
| SHC1 | FLT1 | - | HPRD,BioGRID | 10749680 |
| SHC1 | CBLB | - | HPRD,BioGRID | 9614102 |
| SHC1 | MST1R | - | HPRD,BioGRID | 8918464 |
| SHC1 | AP2A2 | - | HPRD,BioGRID | 8617812 |
| SHC1 | FCGR3A | - | HPRD | 9378963 |
| SHC1 | MAP4K1 | - | HPRD | 9346925 |
| SHC1 | NTRK3 | - | HPRD | 7657612 |
| Reconstituted Complex | BioGRID | 10092678 | ||
| SHC1 | KDR | Affinity Capture-Western | BioGRID | 10319320 |11950700 |
| - | HPRD | 10749680 | ||
| SHC1 | CALD1 | - | HPRD,BioGRID | 10559276 |
| SHC1 | KDR | Affinity Capture-Western | BioGRID | 10319320 |11950700 |
| - | HPRD | 10749680 | ||
| SHC1 | ZAP70 | - | HPRD,BioGRID | 8761298 |9685404 |
| SHC1 | NTRK1 | Shc interacts with Trk. This interaction was modelled on a demonstrated interaction between SHC from rat or mouse and Trk from human. | BIND | 8155326 |
| Shc interacts with NGFR. | BIND | 8577769 | ||
| ShcA interacts with TrkA. | BIND | 7542991 |8610109 |8943228 | ||
| Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 8183561 |9856458 |10092678 |10708759 |12446789 | ||
| SHC1 | ESR1 | - | HPRD,BioGRID | 11773443 |
| SHC1 | MAPK1 | - | HPRD,BioGRID | 10996427 |
| SHC1 | DOK2 | Affinity Capture-Western | BioGRID | 10822173 |
| SHC1 | LTK | - | HPRD,BioGRID | 9223670 |
| SHC1 | PTK2 | - | HPRD,BioGRID | 11980671 |
| Shc interacts with FAK. This interaction was modeled on a demonstrated interaction between human Shc and mouse FAK. | BIND | 9148935 | ||
| SHC1 | IRS1 | Direct interaction between IRS-1 and SHC. This interaction was modeled on a demonstrated interaction between rat IRS-1 and human SHC | BIND | 9202037 |
| - | HPRD,BioGRID | 7499194 | ||
| SHC1 | GRB2 | Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Reconstituted Complex | BioGRID | 7514169 |7524086 |7535773 |8112292 |8195171 |8294403 |8491186 |8647288 |8662733 |9045692 |9083103 |9927207 |10080542 |10477741 |10570290 |11302736 |11505033 |11964172 |12441060 |12577067 |
| Shc interacts with Grb2. This interaction was modelled on a demonstrated interaction between Shc from human and Grb2 from rat and an unspecified species. | BIND | 8084588 | ||
| - | HPRD | 7524086 |7535773 |8491186 |11707405 | ||
| An unspecified isoform of Grb2 interacts with the p52 isoform of Shc. | BIND | 9148935 | ||
| Grb2 interacts with Shc. | BIND | 7515480 |8112292 |8939605 |10891441 | ||
| SHC1 | IGF1R | IGFIR interacts with SHC. | BIND | 7541045 |
| - | HPRD,BioGRID | 8776723 | ||
| SHC1 | RAPGEF1 | - | HPRD,BioGRID | 9344843 |
| SHC1 | CSF3R | - | HPRD,BioGRID | 9824671 |
| SHC1 | DAG1 | - | HPRD,BioGRID | 11724572 |
| SHC1 | ALK | Affinity Capture-Western | BioGRID | 11888936 |
| - | HPRD | 9174053 | ||
| SHC1 | ABL1 | Affinity Capture-Western | BioGRID | 8112292 |10194451 |
| SHC1 | PTPN12 | - | HPRD,BioGRID | 7929214 |8626541 |11432829 |
| SHC1 | GHR | - | HPRD | 9632636 |
| Reconstituted Complex | BioGRID | 7535773 | ||
| SHC1 | BCL3 | - | HPRD | 11707390 |
| SHC1 | PTK2 | - | HPRD,BioGRID | 11980671 |
| Shc interacts with FAK. This interaction was modeled on a demonstrated interaction between human Shc and mouse FAK. | BIND | 9148935 | ||
| SHC1 | CALCOCO2 | Two-hybrid | BioGRID | 16189514 |
| SHC1 | BCR | - | HPRD,BioGRID | 9209414 |
| SHC1 | INSR | - | HPRD | 9083103 |
| Tyrosine-phosphorylated IR interacts with Shc. This interaction was modeled on a demonstrated interaction between human IR and Shc from an unspecified species. | BIND | 10340378 | ||
| SHC1 | GHR | - | HPRD | 9632636 |
| Reconstituted Complex | BioGRID | 7535773 | ||
| SHC1 | SHCBP1 | - | HPRD,BioGRID | 10086341 |
| SHC1 | NTRK1 | Shc interacts with Trk. This interaction was modelled on a demonstrated interaction between SHC from rat or mouse and Trk from human. | BIND | 8155326 |
| Shc interacts with NGFR. | BIND | 8577769 | ||
| ShcA interacts with TrkA. | BIND | 7542991 |8610109 |8943228 | ||
| Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 8183561 |9856458 |10092678 |10708759 |12446789 | ||
| SHC1 | FCGR2A | - | HPRD,BioGRID | 8940017 |10382761 |
| SHC1 | IL4R | - | HPRD,BioGRID | 10652211 |11714803 |
| SHC1 | CEACAM1 | - | HPRD,BioGRID | 11694516 |
| SHC1 | INPP5D | - | HPRD | 8643691 |8723348 |8874179 |
| Affinity Capture-Western | BioGRID | 8643691 |10194451 |10822173 |10900203 |12024011 | ||
| SHC interacts with SHIP1 | BIND | 10822173 | ||
| SHC1 | EPOR | - | HPRD,BioGRID | 8400282 |
| SHC1 | PTPN11 | - | HPRD | 10650943 |
| SHC1 | FGFR1 | - | HPRD | 7514169 |
| SHC1 | INSR | - | HPRD | 9083103 |
| Tyrosine-phosphorylated IR interacts with Shc. This interaction was modeled on a demonstrated interaction between human IR and Shc from an unspecified species. | BIND | 10340378 | ||
| SHC1 | EGFR | Shc interacts with activated EGFR. | BIND | 1623525 |
| ShcA interacts with EGFR. | BIND | 8610109 | ||
| ShcA interacts with the EGFR. | BIND | 8577769 |8610109 |8943228 | ||
| - | HPRD,BioGRID | 9544989 | ||
| EGF-R interacts with Shc. This interaction was modelled on a demonstrated interaction between human EGF-R and mouse Shc. | BIND | 8887653 | ||
| SHC1 | GRB2 | Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Reconstituted Complex | BioGRID | 7514169 |7524086 |7535773 |8112292 |8195171 |8294403 |8491186 |8647288 |8662733 |9045692 |9083103 |9927207 |10080542 |10477741 |10570290 |11302736 |11505033 |11964172 |12441060 |12577067 |
| Shc interacts with Grb2. This interaction was modelled on a demonstrated interaction between Shc from human and Grb2 from rat and an unspecified species. | BIND | 8084588 | ||
| - | HPRD | 7524086 |7535773 |8491186 |11707405 | ||
| An unspecified isoform of Grb2 interacts with the p52 isoform of Shc. | BIND | 9148935 | ||
| Grb2 interacts with Shc. | BIND | 7515480 |8112292 |8939605 |10891441 | ||
| SHC1 | PDGFRB | PDGFR interacts with p52Shc | BIND | 8195171 |
| PDGFR interacts with p66Shc. | BIND | 8195171 | ||
| - | HPRD,BioGRID | 8195171 | ||
| Autophosphorylated PDGFR interacts with SHC. This interaction was modelled on a demonstrated interaction between human PDGFR and SHC from an unspecified species. | BIND | 8890167 | ||
| SHC1 | CBL | - | HPRD,BioGRID | 10570290 |
| SHC1 | INPPL1 | - | HPRD,BioGRID | 9660833 |
| SHC1 | TPR | - | HPRD | 11896612 |
| SHC1 | EPS8 | - | HPRD,BioGRID | 7791787 |
| SHC1 | PIK3C2B | Reconstituted Complex | BioGRID | 11533253 |
| SHC1 | PLSCR1 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 12009895 |12871937 |
| SHC1 | IRS1 | Direct interaction between IRS-1 and SHC. This interaction was modeled on a demonstrated interaction between rat IRS-1 and human SHC | BIND | 9202037 |
| - | HPRD,BioGRID | 7499194 | ||
| SHC1 | RET | RET9 phosphorylates Shc. | BIND | 9047383 |
| - | HPRD,BioGRID | 8183561 |9047384 | ||
| SHC1 | CRKL | - | HPRD,BioGRID | 9344843 |
| SHC1 | FLT4 | - | HPRD | 7675451 |8662748 |9927207 |
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 7970715 |8662748 |9927207 | ||
| SHC1 | EGFR | Shc interacts with activated EGFR. | BIND | 1623525 |
| ShcA interacts with EGFR. | BIND | 8610109 | ||
| ShcA interacts with the EGFR. | BIND | 8577769 |8610109 |8943228 | ||
| - | HPRD,BioGRID | 9544989 | ||
| EGF-R interacts with Shc. This interaction was modelled on a demonstrated interaction between human EGF-R and mouse Shc. | BIND | 8887653 | ||
| SHC1 | NTRK1 | Shc interacts with Trk. This interaction was modelled on a demonstrated interaction between SHC from rat or mouse and Trk from human. | BIND | 8155326 |
| Shc interacts with NGFR. | BIND | 8577769 | ||
| ShcA interacts with TrkA. | BIND | 7542991 |8610109 |8943228 | ||
| Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 8183561 |9856458 |10092678 |10708759 |12446789 | ||
| SHC1 | GRB2 | Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Reconstituted Complex | BioGRID | 7514169 |7524086 |7535773 |8112292 |8195171 |8294403 |8491186 |8647288 |8662733 |9045692 |9083103 |9927207 |10080542 |10477741 |10570290 |11302736 |11505033 |11964172 |12441060 |12577067 |
| Shc interacts with Grb2. This interaction was modelled on a demonstrated interaction between Shc from human and Grb2 from rat and an unspecified species. | BIND | 8084588 | ||
| - | HPRD | 7524086 |7535773 |8491186 |11707405 | ||
| An unspecified isoform of Grb2 interacts with the p52 isoform of Shc. | BIND | 9148935 | ||
| Grb2 interacts with Shc. | BIND | 7515480 |8112292 |8939605 |10891441 | ||
| SHC1 | MAPKAPK2 | - | HPRD,BioGRID | 15094067 |
| SHC1 | LYN | - | HPRD,BioGRID | 7650013 |
| SHC1 | PDGFRB | PDGFR interacts with p52Shc | BIND | 8195171 |
| PDGFR interacts with p66Shc. | BIND | 8195171 | ||
| - | HPRD,BioGRID | 8195171 | ||
| Autophosphorylated PDGFR interacts with SHC. This interaction was modelled on a demonstrated interaction between human PDGFR and SHC from an unspecified species. | BIND | 8890167 | ||
| SHC1 | PIK3R1 | Reconstituted Complex | BioGRID | 7537361 |
| p85 interacts with Shc. | BIND | 8662998 | ||
| - | HPRD | 8662998 | ||
| SHC1 | CD247 | - | HPRD | 8656061 |
| SHC1 | VAV3 | - | HPRD,BioGRID | 11094073 |
| SHC1 | SOS2 | Affinity Capture-Western | BioGRID | 10675333 |
| SHC1 | IRS2 | - | HPRD | 11505033 |
| SHC1 | CSK | - | HPRD,BioGRID | 10037694 |12048194 |
| SHC1 | ERBB3 | - | HPRD | 9694850 |
| Affinity Capture-MS | BioGRID | 16729043 | ||
| SHC1 | DDR1 | - | HPRD | 10783152 |
| DDR1 interacts with Shc. | BIND | 9659899 |10681566 | ||
| SHC1 | MET | - | HPRD | 7731718 |
| Affinity Capture-Western | BioGRID | 9660480 | ||
| SHC1 | ITGB4 | - | HPRD,BioGRID | 11044453 |
| SHC1 | PIK3R1 | Reconstituted Complex | BioGRID | 7537361 |
| p85 interacts with Shc. | BIND | 8662998 | ||
| - | HPRD | 8662998 | ||
| SHC1 | GAB2 | Affinity Capture-Western | BioGRID | 11782427 |12135708 |
| SHC1 | NGFR | - | HPRD,BioGRID | 7541035 |
| SHC1 | EGFR | Shc interacts with activated EGFR. | BIND | 1623525 |
| ShcA interacts with EGFR. | BIND | 8610109 | ||
| ShcA interacts with the EGFR. | BIND | 8577769 |8610109 |8943228 | ||
| - | HPRD,BioGRID | 9544989 | ||
| EGF-R interacts with Shc. This interaction was modelled on a demonstrated interaction between human EGF-R and mouse Shc. | BIND | 8887653 | ||
| SHC1 | PDGFRB | PDGFR interacts with p52Shc | BIND | 8195171 |
| PDGFR interacts with p66Shc. | BIND | 8195171 | ||
| - | HPRD,BioGRID | 8195171 | ||
| Autophosphorylated PDGFR interacts with SHC. This interaction was modelled on a demonstrated interaction between human PDGFR and SHC from an unspecified species. | BIND | 8890167 | ||
| SHC1 | EGFR | Shc interacts with activated EGFR. | BIND | 1623525 |
| ShcA interacts with EGFR. | BIND | 8610109 | ||
| ShcA interacts with the EGFR. | BIND | 8577769 |8610109 |8943228 | ||
| - | HPRD,BioGRID | 9544989 | ||
| EGF-R interacts with Shc. This interaction was modelled on a demonstrated interaction between human EGF-R and mouse Shc. | BIND | 8887653 | ||
| SHC1 | PRKCD | - | HPRD,BioGRID | 12024011 |
| COL1A1 | ITGA5 | - | HPRD | 1693626 |
| COL1A1 | IGFBP3 | - | HPRD,BioGRID | 12735930 |
| COL1A1 | SPARC | - | HPRD | 7034958 |
| Reconstituted Complex | BioGRID | 2745554 | ||
| COL1A1 | PAK1 | - | HPRD,BioGRID | 10772928 |
| COL1A1 | TGFBI | - | HPRD,BioGRID | 11867580 |12034705 |
| COL1A1 | ITGB1 | Co-purification | BioGRID | 2156854 |
| COL1A1 | PDGFB | - | HPRD | 10446987 |
| COL1A1 | DCN | - | HPRD | 1468447 |9675033 |
| COL1A1 | MAG | Reconstituted Complex | BioGRID | 2446864 |
| COL1A1 | CAPN1 | CAPN1 interacts with COL1A1. | BIND | 12358155 |
| COL1A1 | VWF | - | HPRD,BioGRID | 3490481 |
| COL1A1 | CD44 | - | HPRD | 1730778 |
| COL1A1 | FN1 | - | HPRD,BioGRID | 8468356 |
| COL1A1 | TMPRSS6 | - | HPRD,BioGRID | 12149247 |
| COL1A1 | PKD1 | Reconstituted Complex | BioGRID | 11752017 |
| COL1A1 | SPARC | - | HPRD | 7034958 |
| Reconstituted Complex | BioGRID | 2745554 | ||
| COL1A1 | P4HB | - | HPRD | 1339453 |
| COL1A1 | MMP2 | - | HPRD,BioGRID | 11368514 |
| COL1A1 | NID2 | Reconstituted Complex | BioGRID | 9733643 |
| COL1A1 | ITGA2 | Co-purification; in vitro; in vivo | BioGRID | 2156854 |11359786 |11856343 |
| - | HPRD | 2156854|11359786 |11856343 | ||
| COL1A1 | MMP9 | - | HPRD,BioGRID | 9878537 |
| COL1A1 | THBS1 | - | HPRD,BioGRID | 3571333 |
| COL1A1 | PRELP | - | HPRD,BioGRID | 11847210 |
| COL1A1 | ITGA2 | Co-purification; in vitro; in vivo | BioGRID | 2156854 |11359786 |11856343 |
| - | HPRD | 2156854|11359786 |11856343 | ||
| COL1A1 | CD93 | - | HPRD | 1377218 |
| COL1A1 | TXN | Reconstituted Complex; Two-hybrid | BioGRID | 12099690 |
| COL1A1 | BGN | - | HPRD | 7852349 |
| COL1A1 | CD36 | - | HPRD,BioGRID | 2468670 |
| COL1A1 | MATN2 | - | HPRD,BioGRID | 12180907 |
| COL1A1 | COL7A1 | - | HPRD,BioGRID | 9169408 |
| COL1A1 | FGF7 | in vitro | BioGRID | 11973338 |
| COL1A1 | NID1 | - | HPRD,BioGRID | 9733643 |
| COL3A1 | DDR1 | - | HPRD | 9659900 |
| COL3A1 | CAPN1 | CAPN1 interacts with COL3A1. | BIND | 12358155 |
| COL3A1 | MAG | - | HPRD,BioGRID | 2446864 |
| COL3A1 | SPARC | Reconstituted Complex | BioGRID | 2745554 |
| COL3A1 | FGF7 | - | HPRD,BioGRID | 11973338 |
| COL3A1 | THBS1 | - | HPRD,BioGRID | 3571333 |
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