Protein-protein interaction for PEBP1

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Protein-protein interaction data for gene PEBP1

Degree = 1
Interactor A Interactor B Experimental method Source Pubmed
PEBP1STC2Two-hybridBioGRID16169070 
Two-hybridBioGRID16169070 
PEBP1RAF1-HPRD11853019 
RKIP interacts with Raf-1. This interaction was modelled on a demonstrated interaction between RKIP from an unspecified species and Raf-1 from an unspecified species.BIND14654844 
Affinity Capture-Western; Reconstituted ComplexBioGRID10757792 
-HPRD11853019 
RKIP interacts with Raf-1. This interaction was modelled on a demonstrated interaction between RKIP from an unspecified species and Raf-1 from an unspecified species.BIND14654844 
Affinity Capture-Western; Reconstituted ComplexBioGRID10757792 
PEBP1MAPK1-HPRD,BioGRID10757792 
-HPRD,BioGRID10757792 
PEBP1MAP3K7-HPRD,BioGRID11585904 
-HPRD,BioGRID11585904 
PEBP1PRKCAPKCalpha interacts with and phosphorylates RKIP. This interaction was modelled on a demonstrated interaction between RKIP from an unspecified species and human PKCalpha.BIND14654844 
PKCalpha interacts with and phosphorylates RKIP. This interaction was modelled on a demonstrated interaction between RKIP from an unspecified species and human PKCalpha.BIND14654844 
PEBP1MAP2K1-HPRD,BioGRID10757792 
-HPRD,BioGRID10757792 
PEBP1ADRBK1RKIP interacts with GRK-2. This interaction was modelled on a demonstrated interaction between RKIP from an unspecified species and human GRK-2.BIND14654844 
RKIP interacts with GRK-2. This interaction was modelled on a demonstrated interaction between RKIP from an unspecified species and human GRK-2.BIND14654844 
PEBP1PEBP1-HPRD9782050 
-HPRD9782050 
PEBP1PRKCDPKCdelta interacts with and phosphorylates RKIP. This interaction was modelled on a demonstrated interaction between RKIP from an unspecified species and human PKCdelta.BIND14654844 
PKCdelta interacts with and phosphorylates RKIP. This interaction was modelled on a demonstrated interaction between RKIP from an unspecified species and human PKCdelta.BIND14654844 

Degree = 2
Interactor A Interactor B Experimental method Source Pubmed
STC2CARHSP1Two-hybridBioGRID16169070 
STC2POLR3FTwo-hybridBioGRID16169070 
STC2POLR2CTwo-hybridBioGRID16169070 
STC2EIF2B3Two-hybridBioGRID16169070 
STC2ARRB2Two-hybridBioGRID16169070 
STC2FLJ10357Two-hybridBioGRID16169070 
STC2PPP1R8Two-hybridBioGRID16169070 
STC2AIFM1Two-hybridBioGRID16169070 
STC2PTNTwo-hybridBioGRID16169070 
STC2ADAM11Two-hybridBioGRID16169070 
RAF1BCL2L1Reconstituted ComplexBioGRID8929532 
RAF1UBE2D2Biochemical ActivityBioGRID11676916 
RAF1TIMM50C-RAF interacts with TIMM50.BIND12620389 
RAF1 (C-Raf) interacts with TIMM50 (hC22).BIND12620389 
RAF1PRKG1Affinity Capture-WesternBioGRID12237340 
RAF1PAK1-HPRD,BioGRID11733498 
RAF1YWHAE-HPRD,BioGRID7644510 
14-3-3-epsilon interacts with Raf-1.BIND7644510 
RAF1PEBP4Affinity Capture-Western; Reconstituted ComplexBioGRID15302887 
hPEBP4 interacts with Raf-1. This interaction was modeled on a demonstrated interaction between human hPEBP4 and mouse Raf-1.BIND15302887 
RAF1RASD2Reconstituted ComplexBioGRID14724584 
RAF1RRAS2RAF1 (C-Raf) interacts with RRAS2 (R-Ras).BIND12620389 
Reconstituted Complex; Two-hybridBioGRID10557073 |10783161 
-HPRD10064593 
RAF1MAPK7-HPRD,BioGRID10531364 
RAF1GNB2Affinity Capture-WesternBioGRID7782277 
RAF1KSR2-HPRD12975377 
RAF1HRAS-HPRD8530446 |8911690 
Hras interacts with Raf. This interaction was modelled on a demonstrated interaction between Hras and Raf, both from an unspecified species.BIND15705808 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between human Raf and rat Ras.BIND11585923 
RAF1 (C-Raf) interacts with HRAS (Ha-Ras).BIND12620389 
Raf-1 interacts with Ras.BIND15664191 
C-RAF interacts with Ha-Ras.BIND12620389 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between Raf and an unspecified source and human Ras.BIND7523381 |8307946 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID7862125 |7969158 
|8530446 |8628317 
|9150145 |9154803 
|9523700 |10369681 
|10783161 |10882715 
|10922060 |12379659 
|12620389 |14654780 
|14724584 |15031288 
|16803888 
RAF1VDAC1Affinity Capture-WesternBioGRID12079506 
RAF1HRAS-HPRD8530446 |8911690 
Hras interacts with Raf. This interaction was modelled on a demonstrated interaction between Hras and Raf, both from an unspecified species.BIND15705808 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between human Raf and rat Ras.BIND11585923 
RAF1 (C-Raf) interacts with HRAS (Ha-Ras).BIND12620389 
Raf-1 interacts with Ras.BIND15664191 
C-RAF interacts with Ha-Ras.BIND12620389 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between Raf and an unspecified source and human Ras.BIND7523381 |8307946 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID7862125 |7969158 
|8530446 |8628317 
|9150145 |9154803 
|9523700 |10369681 
|10783161 |10882715 
|10922060 |12379659 
|12620389 |14654780 
|14724584 |15031288 
|16803888 
RAF1BRAFB-RAF interacts with C-RAF. This interaction was modelled on a demonstrated interaction between human B-RAF and monkey C-RAF .BIND15035987 
-HPRD,BioGRID11325826 
RAF1TSC22D3-HPRD,BioGRID12391160 
RAF1NRASNras interacts with Raf. This interaction was modelled on a demonstrated interaction between Nras and Raf, both from an unspecified species.BIND15705808 
Affinity Capture-WesternBioGRID10882715 
RAF1HRAS-HPRD8530446 |8911690 
Hras interacts with Raf. This interaction was modelled on a demonstrated interaction between Hras and Raf, both from an unspecified species.BIND15705808 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between human Raf and rat Ras.BIND11585923 
RAF1 (C-Raf) interacts with HRAS (Ha-Ras).BIND12620389 
Raf-1 interacts with Ras.BIND15664191 
C-RAF interacts with Ha-Ras.BIND12620389 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between Raf and an unspecified source and human Ras.BIND7523381 |8307946 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID7862125 |7969158 
|8530446 |8628317 
|9150145 |9154803 
|9523700 |10369681 
|10783161 |10882715 
|10922060 |12379659 
|12620389 |14654780 
|14724584 |15031288 
|16803888 
RAF1CDC25A-HPRD,BioGRID9230211 |10373531 
RAF1OIP5Two-hybridBioGRID12620389 
C-RAF interacts with OIP5.BIND12620389 
RAF1 (C-Raf) interacts with OIP5 (hC73).BIND12620389 
RAF1SPRY2Affinity Capture-WesternBioGRID12717443 
RAF1INSR-HPRD11409918 
RAF1YWHAG-HPRD8702721 |10433554 
Affinity Capture-MS; Affinity Capture-WesternBioGRID10433554 |10620507 
|17353931 
RAF1RBL2Raf-1 interacts with p130.BIND9819434 
-HPRD,BioGRID9819434 
RAF1PRKCZ-HPRD,BioGRID10620507 
RAF1PEX5L-HPRD15302887 
RAF1RB1-HPRD,BioGRID9819434 
Raf-1 interacts with Rb.BIND9819434 
RAF1RRASTwo-hybridBioGRID10848612 
RAF1RAP2ARaf-1 interacts with Rap2. This interaction was modeled on a demonstrated interaction between Raf-1 from unspecified species and human Rap2.BIND15752761 
RAF1TIMM50C-RAF interacts with TIMM50.BIND12620389 
RAF1 (C-Raf) interacts with TIMM50 (hC22).BIND12620389 
RAF1MYC-HPRD,BioGRID9315742 
RAF1CPS1RAF1 (C-Raf) interacts with CPS1.BIND12620389 
C-RAF interacts with CPS1.BIND12620389 
RAF1GNG4-HPRD,BioGRID7782277 
RAF1SHOC2-HPRD,BioGRID10783161 
RAF1PIN1Raf-1 interacts with Pin1. This interaction was modelled on a demonstrated interaction between human Raf-1 and Pin1 from monkey and unspecified species.BIND15664191 
RAF1YWHAG-HPRD8702721 |10433554 
Affinity Capture-MS; Affinity Capture-WesternBioGRID10433554 |10620507 
|17353931 
RAF1ERASAffinity Capture-WesternBioGRID12774123 
RAF1CCT3RAF1 (C-Raf) interacts with CCT3 (hC87).BIND12620389 
C-RAF interacts with CCT3.BIND12620389 
Two-hybridBioGRID12620389 
RAF1NR3C1-HPRD,BioGRID11005817 
RAF1AR-HPRD,BioGRID8349631 
RAF1EFEMP1RAF1 (C-Raf) interacts with an unspecified isoform of EFEMP1 (FBNL).BIND12620389 
RAF1FYN-HPRD,BioGRID7517401 
RAF1HRAS-HPRD8530446 |8911690 
Hras interacts with Raf. This interaction was modelled on a demonstrated interaction between Hras and Raf, both from an unspecified species.BIND15705808 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between human Raf and rat Ras.BIND11585923 
RAF1 (C-Raf) interacts with HRAS (Ha-Ras).BIND12620389 
Raf-1 interacts with Ras.BIND15664191 
C-RAF interacts with Ha-Ras.BIND12620389 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between Raf and an unspecified source and human Ras.BIND7523381 |8307946 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID7862125 |7969158 
|8530446 |8628317 
|9150145 |9154803 
|9523700 |10369681 
|10783161 |10882715 
|10922060 |12379659 
|12620389 |14654780 
|14724584 |15031288 
|16803888 
RAF1YWHABC-RAF interacts with 14-3-3-beta.BIND12620389 
-HPRD8702721 |12360521 
RAF1 (C-Raf) interacts with YWHAB (14-3-3-beta).BIND12620389 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID8702721 |10620507 
|10848612 |12360521 
|12620389 
RAF1YWHABC-RAF interacts with 14-3-3-beta.BIND12620389 
-HPRD8702721 |12360521 
RAF1 (C-Raf) interacts with YWHAB (14-3-3-beta).BIND12620389 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID8702721 |10620507 
|10848612 |12360521 
|12620389 
RAF1RAP1ACo-crystal Structure; Reconstituted Complex; Two-hybridBioGRID7791872 |7862125 
|9867809 |10454553 
-HPRD7791872|9867809|10454553 
RAF1PHB-HPRD,BioGRID10523633 
RAF1 (c-Raf) interacts with PHB.BIND16041367 
RAF1HRAS-HPRD8530446 |8911690 
Hras interacts with Raf. This interaction was modelled on a demonstrated interaction between Hras and Raf, both from an unspecified species.BIND15705808 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between human Raf and rat Ras.BIND11585923 
RAF1 (C-Raf) interacts with HRAS (Ha-Ras).BIND12620389 
Raf-1 interacts with Ras.BIND15664191 
C-RAF interacts with Ha-Ras.BIND12620389 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between Raf and an unspecified source and human Ras.BIND7523381 |8307946 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID7862125 |7969158 
|8530446 |8628317 
|9150145 |9154803 
|9523700 |10369681 
|10783161 |10882715 
|10922060 |12379659 
|12620389 |14654780 
|14724584 |15031288 
|16803888 
RAF1GRB10-HPRD,BioGRID9553107 |10585452 
RAF1KRASAffinity Capture-Western; Two-hybridBioGRID10783161 |10882715 
RAF1YWHAQAffinity Capture-MS; Affinity Capture-Western; Far Western; Reconstituted ComplexBioGRID8663231 |10620507 
|10757792 |17353931 
RAF1JAK1-HPRD,BioGRID9446616 
RAF1HRAS-HPRD8530446 |8911690 
Hras interacts with Raf. This interaction was modelled on a demonstrated interaction between Hras and Raf, both from an unspecified species.BIND15705808 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between human Raf and rat Ras.BIND11585923 
RAF1 (C-Raf) interacts with HRAS (Ha-Ras).BIND12620389 
Raf-1 interacts with Ras.BIND15664191 
C-RAF interacts with Ha-Ras.BIND12620389 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between Raf and an unspecified source and human Ras.BIND7523381 |8307946 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID7862125 |7969158 
|8530446 |8628317 
|9150145 |9154803 
|9523700 |10369681 
|10783161 |10882715 
|10922060 |12379659 
|12620389 |14654780 
|14724584 |15031288 
|16803888 
RAF1MRAS-HPRD,BioGRID10498616 
RAF1YWHABC-RAF interacts with 14-3-3-beta.BIND12620389 
-HPRD8702721 |12360521 
RAF1 (C-Raf) interacts with YWHAB (14-3-3-beta).BIND12620389 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID8702721 |10620507 
|10848612 |12360521 
|12620389 
RAF1SPRY4-HPRD,BioGRID12717443 
RAF1STK3Raf-1 interacts with MST2. This interaction was modeled on a demonstrated interaction between human Raf-1 and monkey MST2.BIND15618521 
RAF1VAV1-HPRD,BioGRID8900182 
RAF1PPP2R2CRAF1 (c-Raf) interacts with an unspecified isoform of PPP2R2C (PP2A-C).BIND16041367 
RAF1CCT3RAF1 (C-Raf) interacts with CCT3 (hC87).BIND12620389 
C-RAF interacts with CCT3.BIND12620389 
Two-hybridBioGRID12620389 
RAF1PPP2R2BRAF1 (c-Raf) interacts with an unspecified isoform of PPP2R2B (PP2A-B).BIND16041367 
RAF1LCK-HPRD,BioGRID8939988 
RAF1BRAFB-RAF interacts with C-RAF. This interaction was modelled on a demonstrated interaction between human B-RAF and monkey C-RAF .BIND15035987 
-HPRD,BioGRID11325826 
RAF1PHKA2Two-hybridBioGRID12620389 
RAF1HRAS-HPRD8530446 |8911690 
Hras interacts with Raf. This interaction was modelled on a demonstrated interaction between Hras and Raf, both from an unspecified species.BIND15705808 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between human Raf and rat Ras.BIND11585923 
RAF1 (C-Raf) interacts with HRAS (Ha-Ras).BIND12620389 
Raf-1 interacts with Ras.BIND15664191 
C-RAF interacts with Ha-Ras.BIND12620389 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between Raf and an unspecified source and human Ras.BIND7523381 |8307946 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID7862125 |7969158 
|8530446 |8628317 
|9150145 |9154803 
|9523700 |10369681 
|10783161 |10882715 
|10922060 |12379659 
|12620389 |14654780 
|14724584 |15031288 
|16803888 
RAF1RBL2Raf-1 interacts with p130.BIND9819434 
-HPRD,BioGRID9819434 
RAF1YWHAZRaf-1 interacts with 14-3-3 zeta. This interaction was modelled on a demonstrated interaction between human Raf-1 and murine 14-3-3-zeta.BIND7559537 
Affinity Capture-Western; Reconstituted ComplexBioGRID7628630 |9261098 
|10620507 |10887173 
-HPRD7628630 |7939632 
RAF1SFNAffinity Capture-MSBioGRID15778465 
RAF1RB1-HPRD,BioGRID9819434 
Raf-1 interacts with Rb.BIND9819434 
RAF1PKM2-HPRD12620389 
C-RAF interacts with PyK.BIND12620389 
RAF1 (C-Raf) interacts with PKM2 (PyK).BIND12620389 
RAF1RHEB-HPRD,BioGRID9001246 
RAF interacts with Rheb.BIND15854902 
RAF1SRC-HPRD,BioGRID7517401 
RAF1MAP3K1MEKK1 interacts with Raf-1.BIND10969079 
Affinity Capture-Western; Reconstituted ComplexBioGRID10969079 
RAF1RP6-213H19.1-HPRD,BioGRID11306563 
RAF1DMPK-HPRD10869570 
RAF1COPS3RAF1 (C-Raf) interacts with COPS3 (SGN3).BIND12620389 
C-RAF interacts with SGN3.BIND12620389 
RAF1LRPAP1Two-hybridBioGRID10783161 
RAF1PHB-HPRD,BioGRID10523633 
RAF1 (c-Raf) interacts with PHB.BIND16041367 
RAF1YWHAZRaf-1 interacts with 14-3-3 zeta. This interaction was modelled on a demonstrated interaction between human Raf-1 and murine 14-3-3-zeta.BIND7559537 
Affinity Capture-Western; Reconstituted ComplexBioGRID7628630 |9261098 
|10620507 |10887173 
-HPRD7628630 |7939632 
RAF1PKM2-HPRD12620389 
C-RAF interacts with PyK.BIND12620389 
RAF1 (C-Raf) interacts with PKM2 (PyK).BIND12620389 
RAF1CNKSR2Affinity Capture-WesternBioGRID14597674 
RAF1OIP5Two-hybridBioGRID12620389 
C-RAF interacts with OIP5.BIND12620389 
RAF1 (C-Raf) interacts with OIP5 (hC73).BIND12620389 
RAF1CFLAR-HPRD,BioGRID10837247 
RAF1YWHABC-RAF interacts with 14-3-3-beta.BIND12620389 
-HPRD8702721 |12360521 
RAF1 (C-Raf) interacts with YWHAB (14-3-3-beta).BIND12620389 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID8702721 |10620507 
|10848612 |12360521 
|12620389 
RAF1RRAS2RAF1 (C-Raf) interacts with RRAS2 (R-Ras).BIND12620389 
Reconstituted Complex; Two-hybridBioGRID10557073 |10783161 
-HPRD10064593 
RAF1MAPK8IP3-HPRD,BioGRID10523642 |11044439 
-HPRD11044439 
RAF1YWHAZRaf-1 interacts with 14-3-3 zeta. This interaction was modelled on a demonstrated interaction between human Raf-1 and murine 14-3-3-zeta.BIND7559537 
Affinity Capture-Western; Reconstituted ComplexBioGRID7628630 |9261098 
|10620507 |10887173 
-HPRD7628630 |7939632 
RAF1NUDT14RAF1 (C-Raf) interacts with NUDT14 (hA21).BIND12620389 
RAF1PBKRAF1 (C-Raf) interacts with PBK (TOPK).BIND12620389 
RAF1CNKSR1-HPRD,BioGRID15075335 
RAF1JAK2-HPRD,BioGRID8876196 
RAF1MAP3K1MEKK1 interacts with Raf-1.BIND10969079 
Affinity Capture-Western; Reconstituted ComplexBioGRID10969079 
RAF1COPS3RAF1 (C-Raf) interacts with COPS3 (SGN3).BIND12620389 
C-RAF interacts with SGN3.BIND12620389 
RAF1HSP90AA1Raf-1 interacts with Hsp90. This interaction was modeled on a demonstrated interaction between human Raf-1 and monkey Hsp90.BIND15618521 
-HPRD,BioGRID8408024 
RAF1AKT1-HPRD,BioGRID10576742 
RAF1PRKCE-HPRD,BioGRID11350735 
RAF1BAG1-HPRD,BioGRID8692945 
RAF1PRPF6Two-hybridBioGRID10848612 
RAF1PEBP4Affinity Capture-Western; Reconstituted ComplexBioGRID15302887 
hPEBP4 interacts with Raf-1. This interaction was modeled on a demonstrated interaction between human hPEBP4 and mouse Raf-1.BIND15302887 
RAF1RRAS2RAF1 (C-Raf) interacts with RRAS2 (R-Ras).BIND12620389 
Reconstituted Complex; Two-hybridBioGRID10557073 |10783161 
-HPRD10064593 
RAF1HRAS-HPRD8530446 |8911690 
Hras interacts with Raf. This interaction was modelled on a demonstrated interaction between Hras and Raf, both from an unspecified species.BIND15705808 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between human Raf and rat Ras.BIND11585923 
RAF1 (C-Raf) interacts with HRAS (Ha-Ras).BIND12620389 
Raf-1 interacts with Ras.BIND15664191 
C-RAF interacts with Ha-Ras.BIND12620389 
Raf interacts with Ras. This interaction was modeled on a demonstrated interaction between Raf and an unspecified source and human Ras.BIND7523381 |8307946 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID7862125 |7969158 
|8530446 |8628317 
|9150145 |9154803 
|9523700 |10369681 
|10783161 |10882715 
|10922060 |12379659 
|12620389 |14654780 
|14724584 |15031288 
|16803888 
RAF1PKM2-HPRD12620389 
C-RAF interacts with PyK.BIND12620389 
RAF1 (C-Raf) interacts with PKM2 (PyK).BIND12620389 
RAF1OIP5Two-hybridBioGRID12620389 
C-RAF interacts with OIP5.BIND12620389 
RAF1 (C-Raf) interacts with OIP5 (hC73).BIND12620389 
RAF1MAPK8IP3-HPRD,BioGRID10523642 |11044439 
-HPRD11044439 
RAF1RAP1ACo-crystal Structure; Reconstituted Complex; Two-hybridBioGRID7791872 |7862125 
|9867809 |10454553 
-HPRD7791872|9867809|10454553 
RAF1MAPK3Affinity Capture-WesternBioGRID11409918 
RAF1PPP2R2ARAF1 (c-Raf) interact with an unspecified isoform of PPP2R2A (PP2A-A).BIND16041367 
RAF1BCL2-HPRD,BioGRID8910675 |8929532 
RAF1MAP3K5-HPRD,BioGRID11427728 
RAF1NRASNras interacts with Raf. This interaction was modelled on a demonstrated interaction between Nras and Raf, both from an unspecified species.BIND15705808 
Affinity Capture-WesternBioGRID10882715 
RAF1MAP2K2Raf interacts with Mek2.BIND14724641 
RAF1RHEB-HPRD,BioGRID9001246 
RAF interacts with Rheb.BIND15854902 
RAF1HSP90AA1Raf-1 interacts with Hsp90. This interaction was modeled on a demonstrated interaction between human Raf-1 and monkey Hsp90.BIND15618521 
-HPRD,BioGRID8408024 
RAF1CPS1RAF1 (C-Raf) interacts with CPS1.BIND12620389 
C-RAF interacts with CPS1.BIND12620389 
RAF1PDGFRB-HPRD,BioGRID2475255 
RAF1YWHAE-HPRD,BioGRID7644510 
14-3-3-epsilon interacts with Raf-1.BIND7644510 
RAF1YWHAH-HPRD,BioGRID8702721 
RAF1CCT3RAF1 (C-Raf) interacts with CCT3 (hC87).BIND12620389 
C-RAF interacts with CCT3.BIND12620389 
Two-hybridBioGRID12620389 
MAPK1RPS6KA5Phenotypic EnhancementBioGRID9687510 
MAPK1SORBS3Affinity Capture-Western; Biochemical ActivityBioGRID15184391 
MAPK1IFNAR1-HPRD9029147 
MAPK1RPS6KA3Affinity Capture-WesternBioGRID8939914 |9915826 
-HPRD12832467 
MAPK1DUSP4-HPRD7535768 
MAPK1MAPKAPK5-HPRD9628874 
MAPK1HSP90AA1-HPRD11748628 
MAPK1SREBF1Biochemical ActivityBioGRID10627507 
MAPK1ADAM17Affinity Capture-Western; Biochemical Activity; Reconstituted ComplexBioGRID12058067 
MAPK1ELK1Mapk1 (p42Mapk) phosphorylates Elk1 at Ser383.BIND15782123 
-HPRD8208531 |8586671 
Biochemical Activity; Reconstituted ComplexBioGRID8586671 |12594221 
MAPK1SREBF2-HPRD,BioGRID10627507 
MAPK1TSC2Affinity Capture-Western; Reconstituted ComplexBioGRID15851026 
Erk2 interacts with TSC2. This interaction was modelled on a demonstrated interaction between Erk2 from an unspecified species and human TSC2.BIND15851026 
MAPK1MAPK14-HPRD,BioGRID12697810 
MAPK1TNFSF11-HPRD10635328 
MAPK1INSRAffinity Capture-WesternBioGRID11409918 
MAPK1TPR-HPRD,BioGRID12594221 
MAPK1THBiochemical ActivityBioGRID1347949 
MAPK1DUSP16-HPRD,BioGRID11489891 
MAPK1TNIP1Naf1-alpha interacts with ERK2.BIND12220502 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID12220502 
MAPK1FHL2Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID14729955 
MAPK1MAPKAPK2Affinity Capture-WesternBioGRID15094067 
MAPK1CALCOCO1KIAA1536 is phosphorylated by MAPK1. This interaction was modeled on a demonstrated interaction between human KIAA1536 and MAPK1 from an unspecified species.BIND15489336 
MAPK1GATA4Biochemical ActivityBioGRID11585926 
MAPK1SNCAAffinity Capture-WesternBioGRID12121974 
-HPRD11279280 
MAPK1DAPK1DAPK interacts with Erk2.BIND15616583 
MAPK1BCL2-HPRD15225643 
MAPK1MBPMBP interacts with MAPK1. This interaction was modeled on a demonstrated interaction between MBP from an unspecified species, and monkey and mouse MAPK1.BIND9792705 
MAPK1MKNK2-HPRD,BioGRID9155017 
MAPK1PECAM1Affinity Capture-WesternBioGRID10801826 
MAPK1EPOR-HPRD12538595 
MAPK1ATF2Biochemical ActivityBioGRID7737129 
MAPK1SNCGAffinity Capture-WesternBioGRID12121974 
MAPK1ESR1-HPRD,BioGRID12093745 
MAPK1KLF11-HPRD12006497 
MAPK1MAPKSP1-HPRD,BioGRID11266467 
MAPK1PEA15-HPRD,BioGRID11702783 
MAPK1DUSP6-HPRD,BioGRID9535927 
-HPRD9535927 |15269220 
MAPK1CEBPBBiochemical ActivityBioGRID11500490 
MAPK1MAP3K1Affinity Capture-WesternBioGRID10969079 
MEKK1 interacts with ERK2.BIND10969079 
MAPK1TSC2Affinity Capture-Western; Reconstituted ComplexBioGRID15851026 
Erk2 interacts with TSC2. This interaction was modelled on a demonstrated interaction between Erk2 from an unspecified species and human TSC2.BIND15851026 
MAPK1HMMRAffinity Capture-WesternBioGRID11403955 
MAPK1TNIP1Naf1-alpha interacts with ERK2.BIND12220502 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID12220502 
MAPK1IER3Biochemical ActivityBioGRID12356731 
MAPK1UBR5-HPRD,BioGRID12594221 
MAPK1DUSP6-HPRD,BioGRID9535927 
-HPRD9535927 |15269220 
MAPK1PTPN7-HPRD,BioGRID10206983 |10702794 
MAPK1ELK1Mapk1 (p42Mapk) phosphorylates Elk1 at Ser383.BIND15782123 
-HPRD8208531 |8586671 
Biochemical Activity; Reconstituted ComplexBioGRID8586671 |12594221 
MAPK1RPS6KA1-HPRD,BioGRID9915826 |12594221 
|12832467 
MAPK1KSR2-HPRD12975377 
MAPK1SHC1-HPRD,BioGRID10996427 
MAPK1PTPRR-HPRD,BioGRID9857190 
MAPK1STAT5B-HPRD10996427 
MAPK1DUSP1-HPRD,BioGRID11278799 
MAPK1ELK1Mapk1 (p42Mapk) phosphorylates Elk1 at Ser383.BIND15782123 
-HPRD8208531 |8586671 
Biochemical Activity; Reconstituted ComplexBioGRID8586671 |12594221 
MAPK1HDAC4-HPRD,BioGRID11114188 
MAPK1DUSP22Affinity Capture-Western; Biochemical ActivityBioGRID11346645 
MAPK1PTPRH-HPRD11278335 
MAPK1VAV1-HPRD,BioGRID8900182 |9013873 
Vav interacts with ERK2.BIND9013873 
MAPK1VAV1-HPRD,BioGRID8900182 |9013873 
Vav interacts with ERK2.BIND9013873 
MAPK1ARReconstituted ComplexBioGRID10318905 
MAPK1MAP2K2MEK2 interacts with ERK2. This interaction is modeled on a demonstrated interaction between human MEK2 and rat ERK2.BIND11134045 
-HPRD,BioGRID11823456 
MAPK1FHL3-HPRD14729955 
MAPK1GMFB-HPRD8639570 
MAPK1RPS6KA2Rsk3 interacts with ERK2. This interaction was modelled on a demonstrated interaction between human Rsk3 and monkey ERK2.BIND9915826 
-HPRD,BioGRID8939914 
MAPK1PTPN5Reconstituted ComplexBioGRID9857190 
MAPK1MKNK1Reconstituted Complex; Two-hybridBioGRID9155017 
MAPK1ATP1A1Biochemical ActivityBioGRID15069082 
MAPK1RPS6KA4-HPRD9687510 
MAPK1RB1RB1 is phosphorylated by MAPK1. This interaction was modeled on a demonstrated interaction between human KIAA1536 and MAPK1 from an unspecified species.BIND15489336 
MAPK1NEK2-HPRD,BioGRID15358203 
MAPK1PRKCEAffinity Capture-WesternBioGRID11350735 
MAPK1DYRK1B-HPRD,BioGRID10910078 
MAPK1TOB1-HPRD,BioGRID12151396 
MAPK1STAT5A-HPRD,BioGRID10194762 |10996427 
MAPK1C1QBP-HPRD,BioGRID11866440 
MAPK1TNKS2Biochemical ActivityBioGRID10988299 
MAPK1MAP2K2MEK2 interacts with ERK2. This interaction is modeled on a demonstrated interaction between human MEK2 and rat ERK2.BIND11134045 
-HPRD,BioGRID11823456 
MAPK1MYCBiochemical Activity; Reconstituted ComplexBioGRID7957875 |9207092 
|15210690 
MAPK1RPS6KA2Rsk3 interacts with ERK2. This interaction was modelled on a demonstrated interaction between human Rsk3 and monkey ERK2.BIND9915826 
-HPRD,BioGRID8939914 
MAPK1RPS6KA3Affinity Capture-WesternBioGRID8939914 |9915826 
-HPRD12832467 
MAPK1DUSP3-HPRD,BioGRID10224087 
MAPK1TP53Affinity Capture-WesternBioGRID10958792 
MAPK1CASP9-HPRD,BioGRID12792650 
MAPK1PLAT-HPRD15861134 
MAPK1SNCAAffinity Capture-WesternBioGRID12121974 
-HPRD11279280 
MAPK1MAP3K1Affinity Capture-WesternBioGRID10969079 
MEKK1 interacts with ERK2.BIND10969079 
MAP3K7RPLP0-HPRD14743216 
MAP3K7FLNA-HPRD14743216 
MAP3K7PELI3-HPRD12874243 
MAP3K7TRAF6-HPRD,BioGRID10094049 
MAP3K7TUBB2B-HPRD14743216 
MAP3K7TRAF3IP2-HPRD12089335 
MAP3K7MAP2K4-HPRD12556533 
MAP3K7ENO1-HPRD14743216 
MAP3K7FOS-HPRD11397816 
MAP3K7MAP3K7IP2-HPRD,BioGRID11259596 
-HPRD11259596 |14743216 
MAP3K7NRIP1-HPRD9556573 
MAP3K7PPM1B-HPRD,BioGRID11104763 
MAP3K7MAP3K7IP2-HPRD,BioGRID11259596 
-HPRD11259596 |14743216 
MAP3K7CLTC-HPRD14743216 
MAP3K7XIAP-HPRD,BioGRID12048196 
MAP3K7SMAD6-HPRD,BioGRID10748100 
MAP3K7RPS3-HPRD14743216 
MAP3K7HSPA1B-HPRD14743216 
MAP3K7TUBB4-HPRD14743216 
MAP3K7HSPA5-HPRD14743216 
MAP3K7MAP4K4-HPRD,BioGRID10807933 
MAP3K7HIST1H4I-HPRD14743216 
MAP3K7HSPA1L-HPRD14743216 
MAP3K7MAP4K1-HPRD,BioGRID10224067 
MAP3K7E2F4E2F4 interacts with MAP3K7 promoter.BIND15782160 
MAP3K7TRAF2Affinity Capture-WesternBioGRID14633987 
-HPRD14743216 
MAP3K7NUDT21-HPRD14743216 
MAP3K7MAP3K5-HPRD,BioGRID10921914 
MAP3K7MAP3K7IP1-HPRD,BioGRID10838074 
An unspecified isoform of TAK1 interacts with TAB1. This interaction was modeled on a demonstrated interaction between TAK1 from an unspecified species and human TAB1.BIND9878061 
-HPRD10838074|14743216 
MAP3K7HGS-HPRD,BioGRID11397816 
MAP3K7NAIP-HPRD11865055 
MAP3K7DARS-HPRD14743216 
MAP3K7RUVBL2-HPRD14743216 
MAP3K7MAP2K6-HPRD,BioGRID11460167 
MAP3K7TRAF2Affinity Capture-WesternBioGRID14633987 
-HPRD14743216 
MAP3K7HSPA9-HPRD14743216 
MAP3K7MAP3K14-HPRD,BioGRID10094049 
MAP3K7DNAJA1-HPRD14743216 
MAP3K7FKBP5-HPRD14743216 
MAP3K7IARS-HPRD14743216 
MAP3K7TNFRSF11A-HPRD,BioGRID11809792 
MAP3K7CDC37-HPRD14743216 
MAP3K7CALM3-HPRD14743216 
MAP3K7EPRS-HPRD14743216 
MAP3K7HSP90AA1-HPRD14743216 
MAP3K7RUVBL1-HPRD14743216 
MAP3K7MAPK8-HPRD11865055 
MAP3K7PPM1L-HPRD12556533 
MAP3K7MAP3K7IP3Affinity Capture-WesternBioGRID14633987 |14670075 
MAP3K7DDX5-HPRD14743216 
MAP3K7CHUK-HPRD,BioGRID10187861 
MAP3K7SMAD7-HPRD,BioGRID12589052 
MAP3K7ACTG1-HPRD14743216 
MAP3K7TUBB2A-HPRD14743216 
MAP3K7MAP3K7IP1-HPRD,BioGRID10838074 
An unspecified isoform of TAK1 interacts with TAB1. This interaction was modeled on a demonstrated interaction between TAK1 from an unspecified species and human TAB1.BIND9878061 
-HPRD10838074|14743216 
MAP3K7HSPA8-HPRD14743216 
MAP3K7CAD-HPRD14743216 
MAP3K7MAP3K7IP1-HPRD,BioGRID10838074 
An unspecified isoform of TAK1 interacts with TAB1. This interaction was modeled on a demonstrated interaction between TAK1 from an unspecified species and human TAB1.BIND9878061 
-HPRD10838074|14743216 
MAP3K7TUBA3C-HPRD14743216 
MAP3K7STRADB-HPRD,BioGRID12048196 
MAP3K7HSP90AB1-HPRD14743216 
MAP3K7EEF1A1-HPRD14743216 
PRKCARGS2-HPRD,BioGRID11063746 
PRKCAACTA1-HPRD,BioGRID10628374 
PRKCAAKAP13AKAP-Lbc interacts with PKC-alpha. This interaction was modeled on a demonstrated interaction between human AKAP-Lbc and rat PKC-alpha.BIND15383279 
PRKCALMNA-HPRD,BioGRID12112001 
PRKCAYWHAZ-HPRD,BioGRID11950841 
PRKCAAKAP12-HPRD,BioGRID11316952 
PRKCAITGB1-HPRD,BioGRID12138200 
PRKCACDC42-HPRD,BioGRID11284700 
PRKCAEGFR-HPRD,BioGRID12878187 
PRKCAPDLIM7-HPRD8940095 
PRKCAPLD2-HPRD,BioGRID11042115 
PRKCAGNB2L1Affinity Capture-WesternBioGRID12435334 
PRKCATEP1-HPRD9837921 
PRKCAHAND1Biochemical ActivityBioGRID14636580 
PRKCAPPP1R14A-HPRD15003508 
PRKCAFSCN1-HPRD,BioGRID14532112 
PRKCATIAM1-HPRD,BioGRID10212259 
PRKCAC1QBP-HPRD,BioGRID10831594 
PRKCAYWHAG-HPRD,BioGRID10433554 
PRKCATERT-HPRD9837921 
PRKCAGABRB3Reconstituted ComplexBioGRID12595241 
PRKCAKCNE4-HPRD12670483 
PRKCASEMG1-HPRD12399526 
PRKCASELLL-selectin interacts with PKC-alpha.BIND15192100 
PRKCATRIM29-HPRD7644499 
PRKCAADAP1-HPRD12893243 
PRKCAGNA12-HPRD8647866 
PRKCACD9-HPRD,BioGRID11325968 
PRKCAAVPR1A-HPRD,BioGRID10858434 
PRKCAMYLK-HPRD3160694 
PRKCAKLF5Biochemical ActivityBioGRID12682370 
PRKCAAVPR1BAffinity Capture-WesternBioGRID10858434 
PRKCADLG4-HPRD,BioGRID11937501 
PRKCADGKZ-HPRD12890670 
PRKCAARHGEF1-HPRD12754211 
PRKCAPLD1-HPRD,BioGRID12839565 
PRKCAGRM7Affinity Capture-WesternBioGRID11007882 
PRKCAEZR-HPRD,BioGRID11387207 
PRKCAGABRR2-HPRD9839716 
PRKCAHAND2-HPRD,BioGRID14636580 
PRKCAAFAP1-HPRD,BioGRID12134071 
PRKCASLC1A1-HPRD,BioGRID12843260 
PRKCAPICK1Affinity Capture-WesternBioGRID11007882 
PRKCAITPKBin vitroBioGRID9374536 
PRKCATP53-HPRD9935181 
PRKCAMBPPKC-alpha phosphorylates and interacts with MBP. This interaction was modeled on a demonstrated interaction between PKC-alpha and MBP, both from unspecified species.BIND10383403 
PRKCASDPR-HPRD9566962 
PRKCAGSK3BBiochemical ActivityBioGRID1324914 
PRKCAATP1A1Biochemical ActivityBioGRID15069082 
PRKCASTXBP3-HPRD10194441 
PRKCARAC1-HPRD,BioGRID11284700 
PRKCAAVPR2Affinity Capture-WesternBioGRID10858434 
PRKCAADCY5-HPRD7759492 |8206971 
PRKCAMGMTBiochemical ActivityBioGRID10667577 
PRKCALMNB1-HPRD,BioGRID11901153 |12135703 
PRKCARHOAin vivoBioGRID11284700 
PRKCAOGG1-HPRD,BioGRID12034821 
PRKCAHABP4-HPRD,BioGRID14699138 
PRKCAGJA1-HPRD,BioGRID11273731 
MAP2K1ROBLD3Affinity Capture-WesternBioGRID11266467 
MAP2K1BRAFMEK1 interacts with B-Raf.BIND8621729 
-HPRD7731720 
MAP2K1MAP3K8Biochemical ActivityBioGRID8631303 
MAP2K1MAPK8IP3-HPRD,BioGRID10523642 |11044439 
MAP2K1RPS6KA2-HPRD8939914 
MAP2K1MAPK3Affinity Capture-Western; Biochemical Activity; Co-localization; Reconstituted Complex; Two-hybridBioGRID8226933 |8626767 
|9006895 |9733512 
|10748187 
MEK1 interacts with ERK1 via a conserved docking site in MEKBIND11134045 
-HPRD8226933 |8626767 
|10748187 
MAP2K1PEBP4-HPRD,BioGRID15302887 
hPEBP4 interacts with MEK1. This interaction was modeled on a demonstrated interaction between human hPEBP4 and mouse MEK1.BIND15302887 
MAP2K1ARAFMEK1 interacts with A-Raf.BIND8621729 
MAP2K1CPNE4-HPRD12522145 
MAP2K1MAP3K1Affinity Capture-WesternBioGRID10969079 
MEKK1 interacts with MEK1.BIND10969079 
MAP2K1MAP3K11MEK1 interacts with MLK3.BIND15258589 
MAP2K1MAPK3Affinity Capture-Western; Biochemical Activity; Co-localization; Reconstituted Complex; Two-hybridBioGRID8226933 |8626767 
|9006895 |9733512 
|10748187 
MEK1 interacts with ERK1 via a conserved docking site in MEKBIND11134045 
-HPRD8226933 |8626767 
|10748187 
MAP2K1MYC-HPRD7957875 
MAP2K1GRB10-HPRD,BioGRID9553107 
MAP2K1MAPKSP1-HPRD,BioGRID9733512 
MAP2K1VAV1Affinity Capture-WesternBioGRID8900182 
MAP2K1MAPK14-HPRD12697810 
MAP2K1MAPK3Affinity Capture-Western; Biochemical Activity; Co-localization; Reconstituted Complex; Two-hybridBioGRID8226933 |8626767 
|9006895 |9733512 
|10748187 
MEK1 interacts with ERK1 via a conserved docking site in MEKBIND11134045 
-HPRD8226933 |8626767 
|10748187 
MAP2K1MAP3K1Affinity Capture-WesternBioGRID10969079 
MEKK1 interacts with MEK1.BIND10969079 
MAP2K1PLAUPhenotypic SuppressionBioGRID10402467 
MAP2K1HRAS-HPRD,BioGRID7969158 
MAP2K1MAP3K4-HPRD,BioGRID9841871 
MAP2K1PEBP4-HPRD,BioGRID15302887 
hPEBP4 interacts with MEK1. This interaction was modeled on a demonstrated interaction between human hPEBP4 and mouse MEK1.BIND15302887 
MAP2K1CPNE1-HPRD12522145 
MAP2K1TRAF3-HPRD8626767 
MAP2K1KSR2-HPRD,BioGRID12975377 
MAP2K1BRAFMEK1 interacts with B-Raf.BIND8621729 
-HPRD7731720 
ADRBK1RCVRN-HPRD12507501 
ADRBK1ADRB2Affinity Capture-WesternBioGRID11309381 
ADRBK1SRC-HPRD,BioGRID12624098 
ADRBK1FSHR-HPRD,BioGRID10379886 
ADRBK1PDCL-HPRD,BioGRID10884381 
ADRBK1AGTR1Affinity Capture-WesternBioGRID9211925 
ADRBK1RHO-HPRD,BioGRID10722682 
ADRBK1PRKCB-HPRD12456365 
Affinity Capture-Western; Reconstituted ComplexBioGRID12679936 
ADRBK1PDC-HPRD,BioGRID10884381 
ADRBK1GNA15Affinity Capture-Western; Reconstituted ComplexBioGRID12885252 
ADRBK1PDE6GAffinity Capture-Western; Reconstituted ComplexBioGRID12624098 
ADRBK1CCR4-HPRD,BioGRID10754297 
ADRBK1ARRB1-HPRD8885248 
ADRBK1AKAP12-HPRD11309381 
ADRBK1PRKCB-HPRD12456365 
Affinity Capture-Western; Reconstituted ComplexBioGRID12679936 
ADRBK1EDNRBAffinity Capture-WesternBioGRID9211925 
ADRBK1FREQ-HPRD12351722 
ADRBK1GIT1-HPRD,BioGRID9826657 
ADRBK1GNAQ-HPRD,BioGRID12885252 
ADRBK1CAV1Reconstituted ComplexBioGRID10085129 
ADRBK1GIT2-HPRD,BioGRID10896954 
PRKCDIGF1RPKC-delta interacts with IGF-IR.BIND11884618 
PRKCDAFAP1-HPRD,BioGRID12134071 
PRKCDTIAM1-HPRD,BioGRID10212259 
PRKCDPLSCR3-HPRD,BioGRID12649167 
PRKCDCD34-HPRD1694174 
PRKCDPPP2CABiochemical ActivityBioGRID11959144 
PRKCDCDCP1PKC-delta interacts with CDCP1.BIND15851033 
PRKCDPRKDC-HPRD9774685 
PRKCDPDP2-HPRD,BioGRID11577086 
PRKCDGNA13-HPRD,BioGRID8824244 
PRKCDPDPK1-HPRD,BioGRID11781095 
PRKCD (PKCD) interacts with PDPK1 (PDK1). This interaction was modelled on a demonstrated interaction between human PRKCD and rat PDPK1.BIND11781095 
PRKCDIL6ST-HPRD,BioGRID12361954 
PKC-delta interacts with gp130. This interaction was modelled on a demonstrated interaction between mouse PKC-delta and human gp130.BIND12361954 
PRKCDFRAP1Affinity Capture-WesternBioGRID10698949 
PRKCDHABP4-HPRD14699138 
PRKCDPIK3CBAffinity Capture-WesternBioGRID11676480 
PRKCDSTAT3PKC-delta interacts with Stat3.BIND10446219 
PRKCDPDK1-HPRD11781095 
PRKCDIRS1-HPRD,BioGRID12031982 
PRKCDC1QBP-HPRD,BioGRID10831594 
PRKCDGNB2L1PKC-delta interacts with RACK1.BIND11884618 
PRKCDPTPN6-HPRD,BioGRID11723252 
PRKCDRIPK4-HPRD,BioGRID10948194 
PRKCDINSR-HPRD,BioGRID11266508 
PRKCDGNA12Biochemical ActivityBioGRID8824244 
PRKCDPTK2B-HPRD,BioGRID11352632 
PRKCDPPM2C-HPRD,BioGRID11577086 
PRKCDGABRA1Affinity Capture-WesternBioGRID12091471 
PRKCDLMNB1-HPRD11901153 
PRKCDIL6ST-HPRD,BioGRID12361954 
PKC-delta interacts with gp130. This interaction was modelled on a demonstrated interaction between mouse PKC-delta and human gp130.BIND12361954 
PRKCDGSK3BPKC-delta interacts with and phosphorylates GSK3-beta. This interaction was modeled on a demonstrated interaction between human PKC-delta and rabbit GSK3-beta.BIND15824731 
PRKCDYWHAG-HPRD,BioGRID10433554 
PRKCDRASGRP3-HPRD,BioGRID15213298 
PRKCDPDPK1-HPRD,BioGRID11781095 
PRKCD (PKCD) interacts with PDPK1 (PDK1). This interaction was modelled on a demonstrated interaction between human PRKCD and rat PDPK1.BIND11781095 
PRKCDTNFRSF10BPRKCD (PKC-delta) interacts with TNFRSF10B (DR5) RARE.BIND12805378 
PRKCDYWHAZAffinity Capture-WesternBioGRID11950841 
PRKCDINPP5DAffinity Capture-WesternBioGRID12024011 
PRKCDADAM9-HPRD,BioGRID9857183 
PRKCDMBPPKC-delta phosphorylates and interacts with MBP. This interaction was modeled on a demonstrated interaction between PKC-delta and MBP, both from unspecified species.BIND10383403 
PRKCDPLD2-HPRD,BioGRID11744693 
PRKCDSTAT1Affinity Capture-WesternBioGRID12807916 
PRKCDMUC1-HPRD,BioGRID11877440 
PRKCDSHC1-HPRD,BioGRID12024011 


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