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Protein-protein interaction for SERPINE1
 Nodes,
degree=1 |
 Nodes,
degree=2 |
Protein-protein interaction data for gene SERPINE1
| Degree = 1 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| SERPINE1 | IGFBP5 | in vitro; in vivo | BioGRID | 9202242 |
| in vitro; in vivo | BioGRID | 9202242 | ||
| SERPINE1 | PLAU | - | HPRD | 2161846 |
| Reconstituted Complex | BioGRID | 9184208 | ||
| - | HPRD | 2161846 | ||
| Reconstituted Complex | BioGRID | 9184208 | ||
| SERPINE1 | ELA2 | - | HPRD | 7521069 |
| - | HPRD | 7521069 | ||
| SERPINE1 | PLG | Reconstituted Complex | BioGRID | 11113116 |
| Reconstituted Complex | BioGRID | 11113116 | ||
| SERPINE1 | THBD | - | HPRD | 12709053 |
| - | HPRD | 12709053 | ||
| SERPINE1 | SERPINE1 | Co-crystal Structure | BioGRID | 10731421 |
| Co-crystal Structure | BioGRID | 10731421 | ||
| SERPINE1 | F2 | Reconstituted Complex | BioGRID | 12709053 |
| Reconstituted Complex | BioGRID | 12709053 | ||
| SERPINE1 | LRP1 | - | HPRD,BioGRID | 15001579 |
| - | HPRD,BioGRID | 15001579 | ||
| SERPINE1 | PLAT | - | HPRD,BioGRID | 2110366 |8607113 |
| - | HPRD,BioGRID | 2110366 |8607113 | ||
| SERPINE1 | ORM1 | - | HPRD,BioGRID | 11418606 |
| - | HPRD,BioGRID | 11418606 | ||
| SERPINE1 | VTN | Reconstituted Complex | BioGRID | 11113116 |
| - | HPRD | 8830783 |11796824 | ||
| Reconstituted Complex | BioGRID | 11113116 | ||
| - | HPRD | 8830783 |11796824 | ||
| SERPINE1 | LRP1B | - | HPRD | 11384978 |
| - | HPRD | 11384978 | ||
| SERPINE1 | LRP2 | - | HPRD | 8344937 |
| - | HPRD | 8344937 | ||
| Degree = 2 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| IGFBP5 | FHL2 | - | HPRD,BioGRID | 11821401 |
| IGFBP5 | IGF2 | IGF-II interacts with IGFBP-5. | BIND | 10407151 |
| - | HPRD,BioGRID | 9497324 | ||
| IGFBP5 | THBS1 | Reconstituted Complex | BioGRID | 10698186 |
| IGFBP-5 interacts with TS-1. | BIND | 15700281 | ||
| IGFBP5 | THBS1 | Reconstituted Complex | BioGRID | 10698186 |
| IGFBP-5 interacts with TS-1. | BIND | 15700281 | ||
| IGFBP5 | SPP1 | - | HPRD,BioGRID | 10698186 |
| IGFBP5 | BAT3 | Two-hybrid | BioGRID | 16169070 |
| IGFBP5 | IGFALS | - | HPRD,BioGRID | 9497324 |9786878 |
| IGFBP5 | IGF2 | IGF-II interacts with IGFBP-5. | BIND | 10407151 |
| - | HPRD,BioGRID | 9497324 | ||
| IGFBP5 | ADAM12 | - | HPRD,BioGRID | 11095942 |
| IGFBP5 | IGF1 | IGF-I interacts with IGFBP-5. | BIND | 10407151 |
| - | HPRD,BioGRID | 9497324 | ||
| IGFBP5 | IGF1 | IGF-I interacts with IGFBP-5. | BIND | 10407151 |
| - | HPRD,BioGRID | 9497324 | ||
| IGFBP5 | TF | - | HPRD | 11297622 |
| PLAU | IGF2R | - | HPRD | 9566979 |
| PLAU | SERPINA5 | Reconstituted Complex | BioGRID | 2551064 |2752144 |
| - | HPRD | 2752144 |9365930 | ||
| PLAU | SERPINB2 | Reconstituted Complex | BioGRID | 8388810 |
| - | HPRD | 2161846 | ||
| PLAU | PLAUR | - | HPRD,BioGRID | 3031025 |11501527 |
| - | HPRD | 11501527 | ||
| PLAU | NID1 | - | HPRD | 1499567 |
| PLAU | SERPINE2 | Reconstituted Complex | BioGRID | 9184208 |
| PLAU | SERPINB2 | Reconstituted Complex | BioGRID | 8388810 |
| - | HPRD | 2161846 | ||
| PLAU | MAP2K1 | Phenotypic Suppression | BioGRID | 10402467 |
| PLAU | PLAUR | - | HPRD,BioGRID | 3031025 |11501527 |
| - | HPRD | 11501527 | ||
| PLAU | SERPINA5 | Reconstituted Complex | BioGRID | 2551064 |2752144 |
| - | HPRD | 2752144 |9365930 | ||
| PLAU | SERPINB6 | - | HPRD | 7548163 |
| PLAU | HRAS | Phenotypic Suppression | BioGRID | 10402467 |
| ELA2 | SERPINF2 | - | HPRD,BioGRID | 2437112 |6980881 |
| ELA2 | SERPINA3 | - | HPRD,BioGRID | 8011628 |8718849 |
| ELA2 | SERPINB13 | - | HPRD | 10512713 |
| ELA2 | SERPING1 | - | HPRD,BioGRID | 6980881 |
| ELA2 | ELN | - | HPRD | 10471600 |
| ELA2 | SERPINB1 | Biochemical Activity; in vitro | BioGRID | 10924364 |
| ELA2 | NOTCH2NL | - | HPRD,BioGRID | 14673143 |
| ELA2 | SDC1 | - | HPRD | 9565572 |
| ELA2 | THBS1 | - | HPRD,BioGRID | 8463250 |
| ELA2 | SERPINA1 | Reconstituted Complex | BioGRID | 10867014 |
| Alpha-1 PI interacts with and inhibits neutrophil elastase. | BIND | 15131125 | ||
| ELA2 | SERPINA1 | Reconstituted Complex | BioGRID | 10867014 |
| Alpha-1 PI interacts with and inhibits neutrophil elastase. | BIND | 15131125 | ||
| ELA2 | KNG1 | - | HPRD,BioGRID | 12887060 |
| ELA2 | SLPI | - | HPRD | 10702419 |
| PLG | LAMA1 | - | HPRD,BioGRID | 8360181 |
| PLG | HMGB1 | - | HPRD,BioGRID | 1909331 |
| PLG | CPB2 | - | HPRD,BioGRID | 1939207 |
| PLG | ENO1 | Reconstituted Complex | BioGRID | 11169399 |
| PLG | CXCL2 | - | HPRD,BioGRID | 10928473 |
| PLG | CLEC3B | - | HPRD | 10964919 |
| PLG | PAPPA | Biochemical Activity | BioGRID | 7586586 |
| PLG | SERPINF2 | - | HPRD,BioGRID | 158022 |2437112 |3334852 |
| PLG | LAMA5 | Reconstituted Complex | BioGRID | 10956663 |
| PLG | ATP5B | - | HPRD | 10077593 |
| PLG | NGF | - | HPRD | 11729324 |
| PLG | HRG | - | HPRD | 8478593 |
| PLG | IGFBP3 | - | HPRD,BioGRID | 9688635 |
| PLG | PRNP | PrPSc interacts with PLG. | BIND | 11438139 |
| PLG | TFPI2 | - | HPRD | 8555184 |
| PLG | KNG1 | - | HPRD,BioGRID | 9428707 |
| PLG | AMOT | - | HPRD | 11257124 |
| PLG | SERPINC1 | - | HPRD | 10974350 |
| PLG | C7 | - | HPRD,BioGRID | 7814888 |
| PLG | F3 | - | HPRD,BioGRID | 9490681 |
| PLG | CHGA | - | HPRD,BioGRID | 11342539 |
| PLG | THBS1 | - | HPRD,BioGRID | 2522013 |
| PLG | ACTG1 | PLG interacts with ACTG1 (G-actin). This interaction was modelled on a demonstrated interaction between human PLG and bovine ACTG1. | BIND | 15746964 |
| PLG | LAMA3 | - | HPRD | 10956663 |
| PLG | F10 | - | HPRD,BioGRID | 11371191 |
| PLG | SPARC | - | HPRD,BioGRID | 2745554 |7982919 |
| PLG | ANXA2 | - | HPRD | 10077593 |
| PLG | S100A10 | - | HPRD,BioGRID | 11939791 |
| THBD | SERPINA5 | - | HPRD | 12878585 |
| THBD | CPB2 | - | HPRD | 8663147 |
| THBD | PROC | - | HPRD | 11106601 |12588872 |
| THBD | PF4 | - | HPRD,BioGRID | 9395524 |
| F2 | SERPIND1 | Co-crystal Structure | BioGRID | 12169660 |
| - | HPRD | 2760054 | ||
| F2 | THBS1 | - | HPRD,BioGRID | 2435757 |
| F2 | C6 | - | HPRD | 3192535 |
| F2 | ITGA5 | - | HPRD | 9864377 |
| F2 | CPB2 | Reconstituted Complex | BioGRID | 8663147 |
| F2 | F2R | Thrombin interacts with PAR1. This interaction was modeled on a demonstrated interaction between Thrombin from an unspecified species and human PAR1. | BIND | 15707890 |
| F2 | SERPING1 | - | HPRD,BioGRID | 11460008 |
| F2 | KNG1 | - | HPRD | 1652157 |
| F2 | SERPINB6 | Reconstituted Complex | BioGRID | 8415716 |
| F2 | F11 | - | HPRD | 1652157 |
| F2 | SERPINC1 | - | HPRD | 3800906 |11927130 |
| F2 | ITGA2B | - | HPRD,BioGRID | 11487023 |
| F2 | F9 | - | HPRD | 15039440 |
| F2 | GP1BA | - | HPRD | 2933256 |
| F2 | FGA | - | HPRD,BioGRID | 1587268 |2133223 |
| F2 | F5 | - | HPRD,BioGRID | 9032460 |
| F2 | SERPINB8 | - | HPRD | 9402754 |
| F2 | F2RL2 | - | HPRD | 12732212 |
| F2 | F2RL3 | - | HPRD | 12732212 |
| F2 | SERPINA5 | - | HPRD | 12878585 |
| F2 | SERPIND1 | Co-crystal Structure | BioGRID | 12169660 |
| - | HPRD | 2760054 | ||
| LRP1 | MAPK8IP2 | Reconstituted Complex; Two-hybrid | BioGRID | 10827173 |
| LRP1 | APBA2 | Two-hybrid | BioGRID | 10827173 |
| LRP1 | APP | - | HPRD | 7543026 |12212791 |
| LRP1 | CTSG | LRP interacts with Cathepsin G. | BIND | 15131125 |
| LRP1 | SHC1 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 11854294 |12789267 |
| - | HPRD | 12069755 |12789267 | ||
| LRP1 | LPL | - | HPRD | 1281473|7510694 |7989348 |
| Reconstituted Complex | BioGRID | 1281473 |7510694 |7989348 | ||
| LRP1 | CALCR | Affinity Capture-Western; Reconstituted Complex | BioGRID | 12821648 |
| LRP1 | SNX17 | Reconstituted Complex | BioGRID | 12169628 |
| LRP1 | MMP13 | - | HPRD | 10514495 |
| LRP1 | SRC | Biochemical Activity | BioGRID | 11854294 |
| LRP1 | CALR | - | HPRD,BioGRID | 12821648 |14980518 |
| LRP1 | SCN3A | Two-hybrid | BioGRID | 10827173 |
| LRP1 | ANAPC10 | - | HPRD,BioGRID | 10827173 |
| LRP1 | MMP15 | - | HPRD | 14645246 |
| LRP1 | SHC1 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 11854294 |12789267 |
| - | HPRD | 12069755 |12789267 | ||
| LRP1 | GULP1 | - | HPRD,BioGRID | 11729193 |
| LRP1 | F9 | - | HPRD,BioGRID | 12522212 |
| LRP1 | FURIN | - | HPRD | 8546712 |
| LRP1 | LTF | - | HPRD | 1464627 |
| LRP1 | MDK | - | HPRD,BioGRID | 10772929 |
| LRP1 | PLAUR | - | HPRD,BioGRID | 11359936 |
| LRP1 | KAT5 | - | HPRD,BioGRID | 12888553 |
| LRP1 | C4BPA | - | HPRD | 11705989 |
| LRP1 | ITGB1BP1 | - | HPRD,BioGRID | 10827173 |
| LRP1 | LRPAP1 | - | HPRD,BioGRID | 1374383 |1718973 |10747918 |
| LRP1 | DAB2 | Reconstituted Complex | BioGRID | 11247302 |
| LRP1 | F8 | - | HPRD,BioGRID | 12522143 |
| LRP1 | SERPINA3 | LRP interacts with alpha-1-ACT. | BIND | 15131125 |
| LRP1 | LIPC | - | HPRD,BioGRID | 7721852 |
| LRP1 | NOS1AP | - | HPRD,BioGRID | 10827173 |
| LRP1 | DLG4 | - | HPRD,BioGRID | 10827173 |
| LRP1 | MMP14 | - | HPRD,BioGRID | 14645246 |
| LRP1 | C3 | - | HPRD | 10608878 |
| LRP1 | PDGFB | - | HPRD,BioGRID | 11854294 |
| LRP1 | CANX | - | HPRD,BioGRID | 14980518 |
| LRP1 | GIPC1 | Reconstituted Complex; Two-hybrid | BioGRID | 10827173 |
| LRP1 | CD82 | - | HPRD | 9804823 |
| LRP1 | MMP16 | - | HPRD | 14645246 |
| LRP1 | APBB1 | - | HPRD,BioGRID | 9837937 |
| LRP1 | THBS1 | - | HPRD,BioGRID | 9045712 |14991768 |
| LRP1 | DAB1 | - | HPRD,BioGRID | 10827173 |
| LRP1 | MAPK8IP1 | - | HPRD,BioGRID | 10827173 |
| LRP1 | CTGF | - | HPRD | 14585398 |
| LRP1 | HSP90B1 | - | HPRD | 11861214 |
| LRP1 | SERPINA1 | LRP interacts with alpha-1-PI. | BIND | 15131125 |
| LRP1 | LPL | - | HPRD | 1281473|7510694 |7989348 |
| Reconstituted Complex | BioGRID | 1281473 |7510694 |7989348 | ||
| LRP1 | PDIA2 | Affinity Capture-Western | BioGRID | 14980518 |
| LRP1 | A2M | - | HPRD,BioGRID | 10652313 |
| LRP1 | SYNJ2BP | - | HPRD,BioGRID | 10827173 |
| LRP1 | APOE | - | HPRD | 11421580 |
| LRP1 | MMP17 | - | HPRD | 14645246 |
| LRP1 | GTPBP1 | - | HPRD | 9820815 |
| PLAT | CALR | - | HPRD,BioGRID | 9359841 |
| PLAT | GRIN1 | - | HPRD | 15448144 |
| PLAT | KRT8 | - | HPRD,BioGRID | 9988531 |
| PLAT | ANXA2 | - | HPRD,BioGRID | 11978811 |12468550 |
| PLAT | SERPINI1 | - | HPRD,BioGRID | 12354288 |
| PLAT | SERPINA5 | - | HPRD,BioGRID | 2551064 |
| PLAT | MAPK3 | - | HPRD | 15861134 |
| PLAT | LAMA1 | - | HPRD,BioGRID | 8360181 |
| PLAT | LAMA3 | - | HPRD | 10956663 |
| PLAT | LAMA5 | Reconstituted Complex | BioGRID | 10956663 |
| PLAT | F10 | - | HPRD,BioGRID | 11371191 |
| PLAT | CKAP4 | - | HPRD | 12913003 |
| PLAT | HMGB1 | - | HPRD,BioGRID | 1909331 |8366113 |
| PLAT | FGA | - | HPRD,BioGRID | 3088041 |11170397 |
| PLAT | CLEC3B | - | HPRD,BioGRID | 12694198 |
| PLAT | SERPING1 | - | HPRD | 7586269 |
| PLAT | SPARC | - | HPRD | 2745554 |
| PLAT | MAPK1 | - | HPRD | 15861134 |
| ORM1 | ALB | - | HPRD | 3795040 |
| VTN | LACRT | - | HPRD,BioGRID | 11419941 |
| VTN | TGFB1 | - | HPRD,BioGRID | 11796824 |
| VTN | PVR | - | HPRD,BioGRID | 11437656 |
| The poliovirus receptor CD 155 interacts with vitronectin. | BIND | 11437656 | ||
| VTN | POMC | - | HPRD,BioGRID | 2475499 |
| VTN | FGF2 | - | HPRD,BioGRID | 11796824 |
| VTN | PVR | - | HPRD,BioGRID | 11437656 |
| The poliovirus receptor CD 155 interacts with vitronectin. | BIND | 11437656 | ||
| VTN | EGF | - | HPRD,BioGRID | 11796824 |
| VTN | PLAUR | - | HPRD | 8830783 |
| VTN | VEGFA | - | HPRD,BioGRID | 11796824 |
| VTN | TGFB2 | - | HPRD,BioGRID | 11796824 |
| VTN | ITGA8 | - | HPRD | 7559467 |
| VTN | KNG1 | - | HPRD,BioGRID | 10887113 |
| VTN | IGF2 | - | HPRD,BioGRID | 10342887 |
| VTN | AMPH | - | HPRD,BioGRID | 12565847 |
| VTN | FGG | - | HPRD | 11744726 |
| LRP1B | APP | - | HPRD | 15126508 |
| LRP1B | PLAUR | - | HPRD | 11384978 |12194987 |
| LRP1B | LRPAP1 | - | HPRD | 11384978 |
| LRP2 | THBS1 | Reconstituted Complex | BioGRID | 7775583 |
| LRP2 | RBP1 | - | HPRD,BioGRID | 10203351 |
| LRP2 | GPRASP1 | - | HPRD | 11274227 |
| LRP2 | TLN1 | - | HPRD | 10827173 |
| LRP2 | APBB1 | - | HPRD | 9837937 |
| LRP2 | APOE | - | HPRD | 11421580 |
| Reconstituted Complex | BioGRID | 7768901 | ||
| LRP2 | GIPC1 | - | HPRD,BioGRID | 11912251 |
| LRP2 | SLC9A3 | - | HPRD | 10364184 |
| LRP2 | ITGB1BP1 | - | HPRD,BioGRID | 10827173 |
| LRP2 | LRPAP1 | - | HPRD,BioGRID | 7512726 |
| LRP2 | NOS1AP | - | HPRD,BioGRID | 10827173 |
| LRP2 | ANAPC10 | Two-hybrid | BioGRID | 10827173 |
| LRP2 | ANKS1B | - | HPRD,BioGRID | 12508107 |
| LRP2 | LPL | - | HPRD,BioGRID | 7686151 |
| LRP2 | MAGI1 | - | HPRD,BioGRID | 11274227 |
| LRP2 | GC | - | HPRD,BioGRID | 11717447 |
| LRP2 | ALB | - | HPRD | 8898021|11158855 |
| LRP2 | DLG1 | - | HPRD | 12713445 |
| LRP2 | CLU | - | HPRD,BioGRID | 7768901 |
| LRP2 | SNX17 | Reconstituted Complex | BioGRID | 12169628 |
| LRP2 | APBA2 | Two-hybrid | BioGRID | 10827173 |
| LRP2 | DAB1 | - | HPRD,BioGRID | 10827173 |
| LRP2 | MDK | - | HPRD | 10772929 |
| LRP2 | SYNJ2BP | - | HPRD,BioGRID | 10827173 |
| LRP2 | TG | - | HPRD | 9492085 |
| LRP2 | ANKRA2 | - | HPRD,BioGRID | 11095640 |
| LRP2 | TTR | - | HPRD | 10982792 |
| LRP2 | SCN3A | Two-hybrid | BioGRID | 10827173 |
| LRP2 | LRP2BP | - | HPRD,BioGRID | 12508107 |
| LRP2 | LPA | - | HPRD,BioGRID | 10073957 |
| LRP2 | APOB | - | HPRD | 10330424 |
| LRP2 | DLG3 | - | HPRD,BioGRID | 12713445 |
| LRP2 | APOE | - | HPRD | 11421580 |
| Reconstituted Complex | BioGRID | 7768901 | ||
| LRP2 | MAPK8IP2 | Reconstituted Complex; Two-hybrid | BioGRID | 10827173 |12508107 |
| LRP2 | DLG2 | - | HPRD,BioGRID | 12713445 |
| LRP2 | APOH | - | HPRD,BioGRID | 9727058 |
| LRP2 | DLG4 | - | HPRD,BioGRID | 12713445 |
| LRP2 | LDLRAP1 | - | HPRD,BioGRID | 14528014 |
| LRP2 | DAB2 | - | HPRD,BioGRID | 10769163 |
| LRP2 | SCGB1A1 | - | HPRD,BioGRID | 11278724 |
| LRP2 | MAPK8IP1 | - | HPRD,BioGRID | 10827173 |
| LRP2 | CUBN | - | HPRD | 11595644|11994745 |
| LRP2 | INS | - | HPRD | 9773776 |
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