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Protein-protein interaction for APH1A
 Nodes,
degree=1 |
 Nodes,
degree=2 |
Protein-protein interaction data for gene APH1A
| Degree = 1 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| APH1A | PSEN1 | APH-1A interacts with PSEN1. | BIND | 12297508 |
| Affinity Capture-Western; Co-fractionation | BioGRID | 12297508 |12471034 |14572442 | ||
| APH1A | PSEN2 | - | HPRD,BioGRID | 12297508 |12471034 |
| APH1A | PSENEN | - | HPRD,BioGRID | 12740439 |14572442 |
| PEN-2 interacts with APH-1. | BIND | 15322109 | ||
| APH1A | NCSTN | - | HPRD,BioGRID | 12297508 |
| Degree = 2 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| PSEN1 | ERN1 | - | HPRD,BioGRID | 10587643 |
| PSEN1 | STX5 | The full-length PS1 holoprotein interacts with Syntaxin 5. | BIND | 15109302 |
| PSEN1 | ICAM5 | - | HPRD,BioGRID | 11719200 |
| PSEN1 | NOTCH1 | Affinity Capture-Western | BioGRID | 10077672 |
| PSEN1 | CTNNB1 | Affinity Capture-Western | BioGRID | 9738936 |9852041 |10341227 |
| PS1 interacts with beta-catenin. | BIND | 9632714 | ||
| PSEN1 | APP | - | HPRD | 10593990 |
| APPswe interacts with PS-1delta-9. | BIND | 14756819 | ||
| PS1 interacts with APP via the APP-C100 fragment. | BIND | 10801777 | ||
| PS1 interacts with APP751. | BIND | 9223340 | ||
| PS1 interacts with APP695. | BIND | 9223340 | ||
| PS1 interacts with APP. | BIND | 15448688 | ||
| PSEN1 | CDH1 | Affinity Capture-Western | BioGRID | 10635315 |
| PSEN1 | KCNIP3 | Affinity Capture-Western | BioGRID | 9771752 |10854253 |
| - | HPRD | 12207970 | ||
| PSEN1 | APP | - | HPRD | 10593990 |
| APPswe interacts with PS-1delta-9. | BIND | 14756819 | ||
| PS1 interacts with APP via the APP-C100 fragment. | BIND | 10801777 | ||
| PS1 interacts with APP751. | BIND | 9223340 | ||
| PS1 interacts with APP695. | BIND | 9223340 | ||
| PS1 interacts with APP. | BIND | 15448688 | ||
| PSEN1 | YME1L1 | - | HPRD,BioGRID | 12214059 |
| PSEN1 | TCF7L2 | - | HPRD,BioGRID | 11504726 |
| PSEN1 | CLSTN1 | Affinity Capture-Western | BioGRID | 15037614 |
| PSEN1 | STX1A | PS1 interacts with syntaxin 1A. | BIND | 10891589 |
| PSEN1 | CTNND2 | PS1 interacts with NPRAP | BIND | 10037471 |
| PSEN1 | CASP4 | PS1 interacts with caspase 4. This interaction was modeled on a demonstrated interaction between human PS1 and mouse caspase 4. | BIND | 10069390 |
| PSEN1 | FLNB | Reconstituted Complex; Two-hybrid | BioGRID | 9437013 |
| PSEN1 | BCL2 | - | HPRD,BioGRID | 10521466 |
| PSEN1 | CASP3 | PS1 interacts with caspase 3. This interaction was modeled on a demonstrated interaction between human PS1 and mouse caspase 3. | BIND | 10069390 |
| PSEN1 | CASP1 | PS-1 interacts with caspase 1. This interaction was modeled on a demonstrated interaction between human PS1 and mouse caspase 1. | BIND | 10069390 |
| PSEN1 | MTCH1 | - | HPRD | 10551805 |
| PSEN1 | CASP7 | PS1 interacts with caspase 7. This interaction was modeled on a demonstrated interaction between human PS1 and mouse caspase 7. | BIND | 10069390 |
| PSEN1 | CIB1 | Two-hybrid | BioGRID | 10366599 |
| PSEN1 | APP | - | HPRD | 10593990 |
| APPswe interacts with PS-1delta-9. | BIND | 14756819 | ||
| PS1 interacts with APP via the APP-C100 fragment. | BIND | 10801777 | ||
| PS1 interacts with APP751. | BIND | 9223340 | ||
| PS1 interacts with APP695. | BIND | 9223340 | ||
| PS1 interacts with APP. | BIND | 15448688 | ||
| PSEN1 | METTL2B | Two-hybrid | BioGRID | 11738826 |
| PSEN1 | APBA1 | - | HPRD | 12196555 |
| PSEN1 | APP | - | HPRD | 10593990 |
| APPswe interacts with PS-1delta-9. | BIND | 14756819 | ||
| PS1 interacts with APP via the APP-C100 fragment. | BIND | 10801777 | ||
| PS1 interacts with APP751. | BIND | 9223340 | ||
| PS1 interacts with APP695. | BIND | 9223340 | ||
| PS1 interacts with APP. | BIND | 15448688 | ||
| PSEN1 | BCL2L1 | - | HPRD,BioGRID | 10446169 |
| PSEN1 | PKP4 | - | HPRD,BioGRID | 10037471 |10092585 |
| PSEN1 | HERPUD1 | - | HPRD,BioGRID | 11799129 |
| PSEN1 | KCNIP3 | Affinity Capture-Western | BioGRID | 9771752 |10854253 |
| - | HPRD | 12207970 | ||
| PSEN1 | GFAP | - | HPRD,BioGRID | 12058025 |
| PSEN1 | APP | - | HPRD | 10593990 |
| APPswe interacts with PS-1delta-9. | BIND | 14756819 | ||
| PS1 interacts with APP via the APP-C100 fragment. | BIND | 10801777 | ||
| PS1 interacts with APP751. | BIND | 9223340 | ||
| PS1 interacts with APP695. | BIND | 9223340 | ||
| PS1 interacts with APP. | BIND | 15448688 | ||
| PSEN1 | FBXW7 | Affinity Capture-Western | BioGRID | 12354302 |
| PSEN1 | CTNNA1 | Affinity Capture-Western | BioGRID | 10635315 |
| PSEN1 | CTNNB1 | Affinity Capture-Western | BioGRID | 9738936 |9852041 |10341227 |
| PS1 interacts with beta-catenin. | BIND | 9632714 | ||
| PSEN1 | KCNIP4 | Two-hybrid | BioGRID | 11847232 |
| PSEN1 | UBQLN1 | Reconstituted Complex; Two-hybrid | BioGRID | 11076969 |
| PSEN1 | CTNND1 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 10208590 |
| PSEN1 | DOCK3 | - | HPRD | 10854253 |
| PSEN1 | MAPT | - | HPRD,BioGRID | 9689133 |
| PSEN1 | APP | - | HPRD | 10593990 |
| APPswe interacts with PS-1delta-9. | BIND | 14756819 | ||
| PS1 interacts with APP via the APP-C100 fragment. | BIND | 10801777 | ||
| PS1 interacts with APP751. | BIND | 9223340 | ||
| PS1 interacts with APP695. | BIND | 9223340 | ||
| PS1 interacts with APP. | BIND | 15448688 | ||
| PSEN1 | APH1B | - | HPRD | 12471034 |
| PSEN2 | APBA3 | Affinity Capture-Western | BioGRID | 12196555 |
| PSEN2 | FLNB | - | HPRD,BioGRID | 9437013 |
| PSEN2 | KCNIP4 | - | HPRD,BioGRID | 11847232 |
| PSEN2 | FHL2 | - | HPRD,BioGRID | 11001931 |
| PSEN2 | CTNND2 | - | HPRD | 10037471 |
| PSEN2 | CAPN1 | - | HPRD,BioGRID | 9852298 |
| PSEN2 | APBA1 | Affinity Capture-Western | BioGRID | 12196555 |
| PSEN2 | APBA2 | Affinity Capture-Western | BioGRID | 12196555 |
| PSEN2 | DOCK3 | - | HPRD | 10854253 |
| PSEN2 | ICAM5 | - | HPRD,BioGRID | 11719200 |
| PSEN2 | APP | PS2 interacts with APP. | BIND | 9223340 |
| PSEN2 | METTL2B | - | HPRD,BioGRID | 11738826 |
| PSEN2 | BCL2L1 | - | HPRD,BioGRID | 10446169 |
| PSEN2 | APH1B | - | HPRD | 12297508 |
| PSEN2 | KCNIP3 | - | HPRD,BioGRID | 9771752 |
| PSEN2 | CIB1 | - | HPRD,BioGRID | 10366599 |
| PSEN2 | SRI | - | HPRD,BioGRID | 10748169 |
| PSEN2 | GFAP | Two-hybrid | BioGRID | 12058025 |
| PSEN2 | UBQLN1 | - | HPRD,BioGRID | 11076969 |
| NCSTN | ABL1 | - | HPRD | 12021275 |
| NCSTN | APP | - | HPRD,BioGRID | 10993067 |
| NCSTN | BACE1 | Nicastrin interacts with BACE1. | BIND | 12054507 |
| - | HPRD,BioGRID | 12054507 | ||
| NCSTN | BACE1 | Nicastrin interacts with BACE1. | BIND | 12054507 |
| - | HPRD,BioGRID | 12054507 | ||
| NCSTN | APH1B | - | HPRD | 12297508 |
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