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Protein-protein interaction for PKLR
 Nodes,
degree=1 |
 Nodes,
degree=2 |
Protein-protein interaction data for gene PKLR
| Degree = 1 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| PKLR | ARHGEF6 | Affinity Capture-Western | BioGRID | 12006652 |
| PKLR | PXN | Affinity Capture-Western | BioGRID | 12006652 |
| PKLR | KIF23 | Affinity Capture-Western | BioGRID | 8524282 |
| PKLR | PAK1 | Affinity Capture-Western | BioGRID | 12006652 |
| Degree = 2 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| ARHGEF6 | PARVB | ARHGEF6 interacts with PARVB | BIND | 12499396 |
| - | HPRD | 12499396 | ||
| ARHGEF6 | GIT1 | - | HPRD | 10896954 |
| Affinity Capture-Western | BioGRID | 10428811 | ||
| ARHGEF6 | PAK3 | - | HPRD,BioGRID | 9659915 |
| ARHGEF6 | RAC1 | ARHGEF6 (Cool-2) interacts with Rac1. | BIND | 15649357 |
| ARHGEF6 | ARHGEF7 | ARHGEF6 interacts with ARHGEF7 | BIND | 12499396 |
| ARHGEF6 | TGFBR2 | T-beta-RII interacts with alpha-PIX. This interaction was modeled on a demonstrated interaction between human T-beta-RII and mouse alpha-PIX. | BIND | 15761153 |
| ARHGEF6 | GIT1 | - | HPRD | 10896954 |
| Affinity Capture-Western | BioGRID | 10428811 | ||
| ARHGEF6 | PARVB | ARHGEF6 interacts with PARVB | BIND | 12499396 |
| - | HPRD | 12499396 | ||
| ARHGEF6 | TGFBR1 | T-beta-RI interacts with alpha-PIX. This interaction was modeled on a demonstrated interaction between human T-beta-RI and mouse alpha-PIX. | BIND | 15761153 |
| ARHGEF6 | CDC42 | ARHGEF6 (Cool-2) interacts with Cdc42. | BIND | 15649357 |
| PXN | GIT1 | GIT1 interacts with Paxillin (PXN). | BIND | 15793570 |
| Affinity Capture-Western | BioGRID | 12629171 | ||
| - | HPRD | 10896954 |12153727 |14523024 | ||
| PXN | GIT1 | GIT1 interacts with Paxillin (PXN). | BIND | 15793570 |
| Affinity Capture-Western | BioGRID | 12629171 | ||
| - | HPRD | 10896954 |12153727 |14523024 | ||
| PXN | VCL | - | HPRD,BioGRID | 9054445 |
| - | HPRD | 7525621 |7534286|9054445 | ||
| PXN | TUBG1 | - | HPRD,BioGRID | 10840040 |11950600 |
| PXN | CTTN | PXN (Paxillin) interacts with an unspecified isoform of CTTN (cortactin). | BIND | 15719014 |
| PXN | IGF1R | Affinity Capture-Western | BioGRID | 10082579 |
| PXN | NCK1 | - | HPRD,BioGRID | 10330411 |
| PXN | GSN | - | HPRD,BioGRID | 11577104 |
| PXN | PARVA | - | HPRD | 11134073 |
| PXN | CRKL | - | HPRD,BioGRID | 7493940 |
| PXN | GIT1 | GIT1 interacts with Paxillin (PXN). | BIND | 15793570 |
| Affinity Capture-Western | BioGRID | 12629171 | ||
| - | HPRD | 10896954 |12153727 |14523024 | ||
| PXN | ASAP2 | in vitro; Reconstituted Complex | BioGRID | 10749932 |12149250 |
| - | HPRD | 10749932|12149250 | ||
| PXN | ILK | - | HPRD,BioGRID | 11304546 |11694518 |
| PXN | SRC | Reconstituted Complex | BioGRID | 10085298 |
| - | HPRD | 7534286 | ||
| PXN | TUBA1B | - | HPRD | 10840040 |
| PXN | ITGA4 | - | HPRD,BioGRID | 11533025 |11919182 |
| Paxillin (PXN) interacts with integrin alpha-4 (ITGA4). | BIND | 10604475 | ||
| PXN | PIK3R1 | Co-purification | BioGRID | 8641358 |
| PXN | GRB2 | Reconstituted Complex | BioGRID | 10085298 |
| PXN | PTK2 | FAK interacts with paxillin. | BIND | 11113628 |
| - | HPRD,BioGRID | 8922390 | ||
| PXN | FYN | - | HPRD,BioGRID | 10804218 |
| PXN | ASAP1 | in vitro | BioGRID | 12149250 |
| PXN | SELE | - | HPRD,BioGRID | 8609175 |
| PXN | ARHGAP5 | Affinity Capture-Western | BioGRID | 10092539 |
| PXN | LCK | - | HPRD,BioGRID | 9488700 |
| PXN | PTPN11 | - | HPRD | 8986614 |10082579 |10655584 |
| PXN | ITGA6 | - | HPRD,BioGRID | 12033289 |
| PXN | TUBA3C | - | HPRD | 10840040 |
| PXN | PTPRH | - | HPRD,BioGRID | 11278335 |
| PXN | RASA1 | - | HPRD,BioGRID | 10092539 |
| PXN | SYK | - | HPRD,BioGRID | 9590268 |
| PXN | SRC | Reconstituted Complex | BioGRID | 10085298 |
| - | HPRD | 7534286 | ||
| PXN | ASAP2 | in vitro; Reconstituted Complex | BioGRID | 10749932 |12149250 |
| - | HPRD | 10749932|12149250 | ||
| PXN | NEDD9 | - | HPRD,BioGRID | 10455189 |
| PXN | REPS2 | - | HPRD,BioGRID | 12149250 |
| PXN | PTEN | - | HPRD,BioGRID | 11857088 |
| PXN | PABPC1 | - | HPRD,BioGRID | 11704675 |
| PXN | RAB8B | Affinity Capture-Western | BioGRID | 12639940 |
| PXN | PTK2 | FAK interacts with paxillin. | BIND | 11113628 |
| - | HPRD,BioGRID | 8922390 | ||
| PXN | TGFB1I1 | Affinity Capture-Western | BioGRID | 11463817 |
| PXN | PTPN12 | - | HPRD | 10085298 |10400685 |10625692 |11950600 |
| Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 9497381 |10400685 |10625692 | ||
| PXN | GIT2 | - | HPRD,BioGRID | 11251077 |
| PXN | TLN1 | - | HPRD,BioGRID | 7534286 |
| PXN | TUBG2 | - | HPRD | 10840040 |
| PXN | PTK2B | - | HPRD,BioGRID | 9099734 |
| PXN | ITGA9 | - | HPRD,BioGRID | 11598204 |
| PXN | LIMK1 | - | HPRD | 15023529 |
| PXN | BCAR1 | Affinity Capture-Western | BioGRID | 8810278 |11577104 |
| PXN | ITGA4 | - | HPRD,BioGRID | 11533025 |11919182 |
| Paxillin (PXN) interacts with integrin alpha-4 (ITGA4). | BIND | 10604475 | ||
| PXN | ITGB3 | Reconstituted Complex | BioGRID | 11683411 |
| PXN | PTPN12 | - | HPRD | 10085298 |10400685 |10625692 |11950600 |
| Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 9497381 |10400685 |10625692 | ||
| PXN | VCL | - | HPRD,BioGRID | 9054445 |
| - | HPRD | 7525621 |7534286|9054445 | ||
| PXN | CRK | - | HPRD,BioGRID | 12198159 |
| PXN | NF2 | - | HPRD,BioGRID | 12118253 |
| PXN | CEACAM1 | - | HPRD,BioGRID | 11035932 |
| PXN | PKD1 | - | HPRD | 11113628 |
| PXN | CSK | - | HPRD,BioGRID | 7529872 |
| PXN | TRIP6 | - | HPRD,BioGRID | 14688263 |
| PXN | ITGB1 | - | HPRD,BioGRID | 7657702|10804218 |
| PXN | PAK3 | - | HPRD | 11096073 |
| PXN | PPP2CA | Affinity Capture-Western | BioGRID | 10675325 |
| PXN | CBL | Co-purification | BioGRID | 8641358 |
| PXN | BCR | Affinity Capture-Western; Co-purification | BioGRID | 7534286 |8641358 |
| PXN | ABL1 | - | HPRD | 9603926 |
| PXN | MATK | - | HPRD,BioGRID | 10080957 |
| KIF23 | RACGAP1 | - | HPRD | 11942621 |
| KIF23 | ARF3 | - | HPRD,BioGRID | 10506747 |
| KIF23 | YWHAG | Affinity Capture-MS | BioGRID | 17353931 |
| - | HPRD | 15324660 | ||
| KIF23 | YWHAB | Affinity Capture-MS | BioGRID | 17353931 |
| KIF23 | PLK1 | - | HPRD | 8524282 |
| KIF23 | YWHAQ | Affinity Capture-MS | BioGRID | 17353931 |
| KIF23 | YWHAG | Affinity Capture-MS | BioGRID | 17353931 |
| - | HPRD | 15324660 | ||
| KIF23 | SFN | Affinity Capture-MS | BioGRID | 15778465 |
| PAK1 | SPEN | Pak1 phosphorylates SHARP. This interaction was modeled on a demonstrated interaction between Pak1 and SHARP both from an unspecified species. | BIND | 15824732 |
| PAK1 | AKT1 | Reconstituted Complex | BioGRID | 14749719 |
| PAK1 | RAF1 | - | HPRD,BioGRID | 11733498 |
| PAK1 | HGS | - | HPRD,BioGRID | 11397816 |
| PAK1 | RAC1 | PAK1 interacts with an unspecified isoform of Rac. This interaction was modeled on a demonstrated interaction between human PAK1 and Rac from Chinese hamster. | BIND | 15975516 |
| PAK1 interacts with an unspecified isoform of Rac. This interaction was modeled on a demonstrated interaction between PAK1 from an unspecified species and human Rac. | BIND | 15864311 | ||
| - | HPRD | 7744004 |8107774 |11134022 |11950930|11134022 | ||
| Reconstituted Complex | BioGRID | 12650940 |12879077 | ||
| Active GTP-bound RAC1 interacts with PAK1B. This interaction was modelled on a demonstrated interaction between chicken RAC1 and human PAK1B. | BIND | 15735674 | ||
| Rac1 interacts with Pak1. This interaction was modeled on a demonstrated interaction between Rac1 and Pak1 from an unspecified species. | BIND | 15652748 | ||
| Rac1 interacts with Pak1. This interaction was modelled on a demonstrated interacton between Rac1 from an unspecified species and human Pak1. | BIND | 12944407 | ||
| PAK1 | RAC1 | PAK1 interacts with an unspecified isoform of Rac. This interaction was modeled on a demonstrated interaction between human PAK1 and Rac from Chinese hamster. | BIND | 15975516 |
| PAK1 interacts with an unspecified isoform of Rac. This interaction was modeled on a demonstrated interaction between PAK1 from an unspecified species and human Rac. | BIND | 15864311 | ||
| - | HPRD | 7744004 |8107774 |11134022 |11950930|11134022 | ||
| Reconstituted Complex | BioGRID | 12650940 |12879077 | ||
| Active GTP-bound RAC1 interacts with PAK1B. This interaction was modelled on a demonstrated interaction between chicken RAC1 and human PAK1B. | BIND | 15735674 | ||
| Rac1 interacts with Pak1. This interaction was modeled on a demonstrated interaction between Rac1 and Pak1 from an unspecified species. | BIND | 15652748 | ||
| Rac1 interacts with Pak1. This interaction was modelled on a demonstrated interacton between Rac1 from an unspecified species and human Pak1. | BIND | 12944407 | ||
| PAK1 | NCK1 | - | HPRD | 8824201 |11278241 |
| Nck interacts with PAK1 | BIND | 8824201 | ||
| - | HPRD,BioGRID | 8824201 | ||
| PAK1 | CSNK2A1 | - | HPRD | 10938077 |
| PAK1 | RHOJ | - | HPRD,BioGRID | 10967094 |
| PAK1 | NF2 | Merlin interacts with Pak1 | BIND | 14580336 |
| - | HPRD | 14580336 | ||
| PAK1 | RAC1 | PAK1 interacts with an unspecified isoform of Rac. This interaction was modeled on a demonstrated interaction between human PAK1 and Rac from Chinese hamster. | BIND | 15975516 |
| PAK1 interacts with an unspecified isoform of Rac. This interaction was modeled on a demonstrated interaction between PAK1 from an unspecified species and human Rac. | BIND | 15864311 | ||
| - | HPRD | 7744004 |8107774 |11134022 |11950930|11134022 | ||
| Reconstituted Complex | BioGRID | 12650940 |12879077 | ||
| Active GTP-bound RAC1 interacts with PAK1B. This interaction was modelled on a demonstrated interaction between chicken RAC1 and human PAK1B. | BIND | 15735674 | ||
| Rac1 interacts with Pak1. This interaction was modeled on a demonstrated interaction between Rac1 and Pak1 from an unspecified species. | BIND | 15652748 | ||
| Rac1 interacts with Pak1. This interaction was modelled on a demonstrated interacton between Rac1 from an unspecified species and human Pak1. | BIND | 12944407 | ||
| PAK1 | PAK1IP1 | - | HPRD,BioGRID | 11371639 |
| PAK1 | PPM1F | - | HPRD | 11864573 |
| PAK1 | COL1A1 | - | HPRD,BioGRID | 10772928 |
| PAK1 | CDC42 | Reconstituted Complex | BioGRID | 12650940 |
| PAK1 interacts with an unspecified isoform of Cdc42. This interaction was modeled on a demonstrated interaction between PAK1 from an unspecified species and human Cdc42. | BIND | 15864311 | ||
| - | HPRD | 7744004 |8107774 |9705280|9705280 | ||
| Cdc42 interacts with Pak1. This interaction was modelled on a demonstrated interaction between Cdc42 from an unspecified species and human Pak1. | BIND | 12944407 | ||
| PAK1 | PLCG1 | - | HPRD,BioGRID | 12085993 |
| PAK1 | CDC42 | Reconstituted Complex | BioGRID | 12650940 |
| PAK1 interacts with an unspecified isoform of Cdc42. This interaction was modeled on a demonstrated interaction between PAK1 from an unspecified species and human Cdc42. | BIND | 15864311 | ||
| - | HPRD | 7744004 |8107774 |9705280|9705280 | ||
| Cdc42 interacts with Pak1. This interaction was modelled on a demonstrated interaction between Cdc42 from an unspecified species and human Pak1. | BIND | 12944407 | ||
| PAK1 | CDK5R1 | - | HPRD | 11604394 |
| PAK1 | CDC42 | Reconstituted Complex | BioGRID | 12650940 |
| PAK1 interacts with an unspecified isoform of Cdc42. This interaction was modeled on a demonstrated interaction between PAK1 from an unspecified species and human Cdc42. | BIND | 15864311 | ||
| - | HPRD | 7744004 |8107774 |9705280|9705280 | ||
| Cdc42 interacts with Pak1. This interaction was modelled on a demonstrated interaction between Cdc42 from an unspecified species and human Pak1. | BIND | 12944407 | ||
| PAK1 | RHOU | Wrch-1 interacts with PAK. This interaction was modeled on a demonstrated interactions between human Wrch-1 and rat PAK. | BIND | 15556869 |
| PAK1 | RAC1 | PAK1 interacts with an unspecified isoform of Rac. This interaction was modeled on a demonstrated interaction between human PAK1 and Rac from Chinese hamster. | BIND | 15975516 |
| PAK1 interacts with an unspecified isoform of Rac. This interaction was modeled on a demonstrated interaction between PAK1 from an unspecified species and human Rac. | BIND | 15864311 | ||
| - | HPRD | 7744004 |8107774 |11134022 |11950930|11134022 | ||
| Reconstituted Complex | BioGRID | 12650940 |12879077 | ||
| Active GTP-bound RAC1 interacts with PAK1B. This interaction was modelled on a demonstrated interaction between chicken RAC1 and human PAK1B. | BIND | 15735674 | ||
| Rac1 interacts with Pak1. This interaction was modeled on a demonstrated interaction between Rac1 and Pak1 from an unspecified species. | BIND | 15652748 | ||
| Rac1 interacts with Pak1. This interaction was modelled on a demonstrated interacton between Rac1 from an unspecified species and human Pak1. | BIND | 12944407 | ||
| PAK1 | ABI3 | - | HPRD,BioGRID | 11956071 |
| PAK1 | DYNLL1 | Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid | BioGRID | 15193260 |
| PAK1 | NCF1C | Pak1 interacts with and phosphorylates P47. This interaction was modeled on a demonstrated interaction between Pak1 and P47 from unspecified species. | BIND | 15225553 |
| PAK1 | ARPC1B | - | HPRD,BioGRID | 14749719 |
| PAK1 | NCK2 | - | HPRD,BioGRID | 10026169 |11557983 |
| PAK1 | BAIAP2 | Reconstituted Complex | BioGRID | 11130076 |
| PAK1 | NCK1 | - | HPRD | 8824201 |11278241 |
| Nck interacts with PAK1 | BIND | 8824201 | ||
| - | HPRD,BioGRID | 8824201 | ||
| PAK1 | RAC1 | PAK1 interacts with an unspecified isoform of Rac. This interaction was modeled on a demonstrated interaction between human PAK1 and Rac from Chinese hamster. | BIND | 15975516 |
| PAK1 interacts with an unspecified isoform of Rac. This interaction was modeled on a demonstrated interaction between PAK1 from an unspecified species and human Rac. | BIND | 15864311 | ||
| - | HPRD | 7744004 |8107774 |11134022 |11950930|11134022 | ||
| Reconstituted Complex | BioGRID | 12650940 |12879077 | ||
| Active GTP-bound RAC1 interacts with PAK1B. This interaction was modelled on a demonstrated interaction between chicken RAC1 and human PAK1B. | BIND | 15735674 | ||
| Rac1 interacts with Pak1. This interaction was modeled on a demonstrated interaction between Rac1 and Pak1 from an unspecified species. | BIND | 15652748 | ||
| Rac1 interacts with Pak1. This interaction was modelled on a demonstrated interacton between Rac1 from an unspecified species and human Pak1. | BIND | 12944407 | ||
| PAK1 | TGFBR2 | T-beta-RII interacts with PAK1. This interaction was modeled on a demonstrated interaction between human T-beta-RII and mouse PAK1. | BIND | 15761153 |
| PAK1 | GRB2 | PAK1 interacts with Grb2. | BIND | 12522133 |
| PAK1 | CSNK2A2 | - | HPRD | 10938077 |
| PAK1 | HIST4H4 | PAK1 phosphorylates H4. This interaction was modeled on a demonstrated interaction between human PAK1 and H4 from an unspecified species. | BIND | 15864311 |
| PAK1 | MYLK | - | HPRD,BioGRID | 10092231 |
| PAK1 | NF2 | Merlin interacts with Pak1 | BIND | 14580336 |
| - | HPRD | 14580336 | ||
| PAK1 | LIMK1 | - | HPRD,BioGRID | 10559936 |
| PAK1 | CDC2L2 | - | HPRD,BioGRID | 12624090 |
| PAK1 | CDC42 | Reconstituted Complex | BioGRID | 12650940 |
| PAK1 interacts with an unspecified isoform of Cdc42. This interaction was modeled on a demonstrated interaction between PAK1 from an unspecified species and human Cdc42. | BIND | 15864311 | ||
| - | HPRD | 7744004 |8107774 |9705280|9705280 | ||
| Cdc42 interacts with Pak1. This interaction was modelled on a demonstrated interaction between Cdc42 from an unspecified species and human Pak1. | BIND | 12944407 | ||
| PAK1 | NCK1 | - | HPRD | 8824201 |11278241 |
| Nck interacts with PAK1 | BIND | 8824201 | ||
| - | HPRD,BioGRID | 8824201 | ||
| PAK1 | RAC1 | PAK1 interacts with an unspecified isoform of Rac. This interaction was modeled on a demonstrated interaction between human PAK1 and Rac from Chinese hamster. | BIND | 15975516 |
| PAK1 interacts with an unspecified isoform of Rac. This interaction was modeled on a demonstrated interaction between PAK1 from an unspecified species and human Rac. | BIND | 15864311 | ||
| - | HPRD | 7744004 |8107774 |11134022 |11950930|11134022 | ||
| Reconstituted Complex | BioGRID | 12650940 |12879077 | ||
| Active GTP-bound RAC1 interacts with PAK1B. This interaction was modelled on a demonstrated interaction between chicken RAC1 and human PAK1B. | BIND | 15735674 | ||
| Rac1 interacts with Pak1. This interaction was modeled on a demonstrated interaction between Rac1 and Pak1 from an unspecified species. | BIND | 15652748 | ||
| Rac1 interacts with Pak1. This interaction was modelled on a demonstrated interacton between Rac1 from an unspecified species and human Pak1. | BIND | 12944407 | ||
| PAK1 | EGFR | Tyrosine-phosphorylated EGFR interacts with PAK1. | BIND | 12522133 |
| PAK1 | BMX | - | HPRD,BioGRID | 11382770 |
| PAK1 | ARHGDIA | Pak1 interacts with and phosphorylates RhoGDI. This interaction was modeled on a demonstrated interaction between Pak1 from an unspecified species and human RhoGDI. | BIND | 15225553 |
| PAK1 | CDK5 | Affinity Capture-Western; Biochemical Activity | BioGRID | 11604394 |
| PAK1 | ARHGEF7 | - | HPRD,BioGRID | 11157752|12006652 |
| PAK1 | RAC1 | PAK1 interacts with an unspecified isoform of Rac. This interaction was modeled on a demonstrated interaction between human PAK1 and Rac from Chinese hamster. | BIND | 15975516 |
| PAK1 interacts with an unspecified isoform of Rac. This interaction was modeled on a demonstrated interaction between PAK1 from an unspecified species and human Rac. | BIND | 15864311 | ||
| - | HPRD | 7744004 |8107774 |11134022 |11950930|11134022 | ||
| Reconstituted Complex | BioGRID | 12650940 |12879077 | ||
| Active GTP-bound RAC1 interacts with PAK1B. This interaction was modelled on a demonstrated interaction between chicken RAC1 and human PAK1B. | BIND | 15735674 | ||
| Rac1 interacts with Pak1. This interaction was modeled on a demonstrated interaction between Rac1 and Pak1 from an unspecified species. | BIND | 15652748 | ||
| Rac1 interacts with Pak1. This interaction was modelled on a demonstrated interacton between Rac1 from an unspecified species and human Pak1. | BIND | 12944407 | ||
| PAK1 | ARHGEF2 | Affinity Capture-MS; Reconstituted Complex | BioGRID | 14970201 |
| PAK1 | ERBB2 | - | HPRD,BioGRID | 9774445 |
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