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Protein-protein interaction for RPRM
 Nodes,
degree=1 |
 Nodes,
degree=2 |
Protein-protein interaction data for gene RPRM
| Degree = 1 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| RPRM | CUL1 | Affinity Capture-MS | BioGRID | 17353931 |
| RPRM | MEN1 | Affinity Capture-MS | BioGRID | 17353931 |
| RPRM | FBXW11 | Affinity Capture-MS | BioGRID | 17353931 |
| RPRM | CDK4 | Affinity Capture-MS | BioGRID | 17353931 |
| Degree = 2 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| CUL1 | SKP1 | - | HPRD | 9827542 |
| Affinity Capture-Western | BioGRID | 9430629 |12609982 |12628165 | ||
| SKP1A interacts with Cul1 [15-410] to form part of the Cul1-Rbx1-Skp1-F Boxskp2 Scf Ubiquitin Ligase complex. | BIND | 11961546 | ||
| CUL1 | TBK1 | Affinity Capture-MS | BioGRID | 14743216 |
| CUL1 | PRPF40A | - | HPRD | 14603323 |
| CUL1 | RAC2 | - | HPRD,BioGRID | 11445862 |
| CUL1 | FBXO7 | Affinity Capture-Western | BioGRID | 10531035 |
| CUL1 | SKP1 | - | HPRD | 9827542 |
| Affinity Capture-Western | BioGRID | 9430629 |12609982 |12628165 | ||
| SKP1A interacts with Cul1 [15-410] to form part of the Cul1-Rbx1-Skp1-F Boxskp2 Scf Ubiquitin Ligase complex. | BIND | 11961546 | ||
| CUL1 | E2F1 | - | HPRD,BioGRID | 10559858 |
| CUL1 | SKP1 | - | HPRD | 9827542 |
| Affinity Capture-Western | BioGRID | 9430629 |12609982 |12628165 | ||
| SKP1A interacts with Cul1 [15-410] to form part of the Cul1-Rbx1-Skp1-F Boxskp2 Scf Ubiquitin Ligase complex. | BIND | 11961546 | ||
| CUL1 | COPS6 | - | HPRD | 11337588 |
| CUL1 | PARK2 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 12628165 |
| CUL1 | CDK9 | - | HPRD,BioGRID | 11689688 |12861003 |
| CUL1 | FBXL3 | Affinity Capture-Western | BioGRID | 10531035 |
| CUL1 | RNF7 | - | HPRD,BioGRID | 10230407 |
| CUL1 | CDCA3 | - | HPRD,BioGRID | 12679038 |
| CUL1 | CDKN1C | Biochemical Activity | BioGRID | 12925736 |
| CUL1 | FBXO4 | Affinity Capture-MS; Affinity Capture-Western | BioGRID | 10531035 |17353931 |
| CUL1 | RBX1 | CUL1 interacts with ROC1. | BIND | 11956208 |
| - | HPRD,BioGRID | 11961546 | ||
| Rbx1 interacts with Cul1 [411-776] to form part of the Cul1-Rbx1-Skp1-F Boxskp2 Scf Ubiquitin Ligase complex. | BIND | 11961546 | ||
| CUL1 | CDT1 | Affinity Capture-Western | BioGRID | 12840033 |
| CUL1 | RBX1 | CUL1 interacts with ROC1. | BIND | 11956208 |
| - | HPRD,BioGRID | 11961546 | ||
| Rbx1 interacts with Cul1 [411-776] to form part of the Cul1-Rbx1-Skp1-F Boxskp2 Scf Ubiquitin Ligase complex. | BIND | 11961546 | ||
| CUL1 | RBX1 | CUL1 interacts with ROC1. | BIND | 11956208 |
| - | HPRD,BioGRID | 11961546 | ||
| Rbx1 interacts with Cul1 [411-776] to form part of the Cul1-Rbx1-Skp1-F Boxskp2 Scf Ubiquitin Ligase complex. | BIND | 11961546 | ||
| CUL1 | FBXW7 | Reconstituted Complex | BioGRID | 11585921 |
| CUL1 | SKP2 | - | HPRD,BioGRID | 9430629 |
| Skp2-Fbox interacts with Cul1 [15-410] to form part of the Cul1-Rbx1-Skp1-F Boxskp2 Scf Ubiquitin Ligase complex. | BIND | 11961546 | ||
| CUL1 | FBXW2 | Affinity Capture-Western | BioGRID | 10531035 |
| CUL1 | COMMD1 | Murr1 interacts with Cul1 a component of the Cul1-Rbx1-Skp1-F Box Scf Ubiquitin Ligase complex. | BIND | 14685242 |
| CUL1 | GPS1 | - | HPRD | 11337588 |
| CUL1 | CAND1 | Affinity Capture-MS; Affinity Capture-Western | BioGRID | 12609982 |
| CUL1 | SKP2 | - | HPRD,BioGRID | 9430629 |
| Skp2-Fbox interacts with Cul1 [15-410] to form part of the Cul1-Rbx1-Skp1-F Boxskp2 Scf Ubiquitin Ligase complex. | BIND | 11961546 | ||
| CUL1 | BTRC | Affinity Capture-Western | BioGRID | 10531035 |10644755 |12609982 |
| CUL1 | FBXO18 | - | HPRD,BioGRID | 11956208 |
| MEN1 | RELA | - | HPRD,BioGRID | 11526476 |
| MEN1 | SMAD3 | - | HPRD,BioGRID | 11274402 |
| MEN1 | GFAP | - | HPRD,BioGRID | 12169273 |
| MEN1 | VIM | menin interacts with vimentin | BIND | 12169273 |
| - | HPRD,BioGRID | 12169273 | ||
| MEN1 | DBF4 | Menin interacts with ASK. | BIND | 15374998 |
| MEN1 | VIM | menin interacts with vimentin | BIND | 12169273 |
| - | HPRD,BioGRID | 12169273 | ||
| MEN1 | NFKB2 | - | HPRD,BioGRID | 11526476 |
| MEN1 | MLL | Affinity Capture-Western; Co-purification | BioGRID | 15199122 |
| MEN1 | NFKB1 | - | HPRD,BioGRID | 11526476 |
| MEN1 | FANCD2 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 12874027 |
| MEN1 | ASH2L | Reconstituted Complex | BioGRID | 15199122 |
| MEN1 | JUND | - | HPRD,BioGRID | 9989505 |12226747 |
| Menin directly represses JunD-activated transcription | BIND | 10500243 | ||
| MEN1 | RPA2 | - | HPRD,BioGRID | 12509449 |
| MEN1 | RBBP5 | Co-purification | BioGRID | 15199122 |
| MEN1 | JUND | - | HPRD,BioGRID | 9989505 |12226747 |
| Menin directly represses JunD-activated transcription | BIND | 10500243 | ||
| MEN1 | HCFC1 | Co-purification | BioGRID | 15199122 |
| MEN1 | WDR5 | Co-purification | BioGRID | 15199122 |
| MEN1 | HCFC2 | Co-purification | BioGRID | 15199122 |
| FBXW11 | BTRC | - | HPRD,BioGRID | 10644755 |
| FBXW11 | WEE1 | Wee1A interacts with an unspecified isoform of beta-TrCP2. | BIND | 15070733 |
| FBXW11 | SKP1 | Affinity Capture-Western | BioGRID | 10644755 |
| FBXW11 | CDC25A | - | HPRD | 14603323 |
| FBXW11 | NFKBIA | - | HPRD,BioGRID | 10644755 |
| FBXW11 | CUL7 | - | HPRD | 12481031 |
| CDK4 | VTA1 | Two-hybrid | BioGRID | 16189514 |
| CDK4 | CDKN2D | Two-hybrid | BioGRID | 16189514 |
| CDK4 | ACTR3B | Affinity Capture-MS | BioGRID | 17353931 |
| CDK4 | RFC1 | - | HPRD,BioGRID | 10353443 |
| CDK4 | BAT3 | Two-hybrid | BioGRID | 16169070 |
| CDK4 | CNOT7 | - | HPRD,BioGRID | 10602502 |
| CDK4 | CDKN2A | p16 interacts with cdk4. This interaction was modeled on a demonstrated interaction between human p16 and cdk4 from an unspecified species. | BIND | 9482104 |
| CDKN2A interacts with CDK4 | BIND | 11556834 | ||
| - | HPRD,BioGRID | 9228064 | ||
| - | HPRD | 9228064 |15232106 | ||
| p16 interacts with CDK4. This interaction was modeled on a demonstrated interaction between human p16 and CDK4 from an unspecified species. | BIND | 10491434 | ||
| p16 interacts with cdk4. | BIND | 8805225 | ||
| CDK4 | CCND1 | - | HPRD | 9150368 |9837900 |
| CDK4 interacts with Cyclin D1. This interaction was modelled on a demonstrated interaction between human CDK4 and Cyclin D1 from an unspecified species. | BIND | 9228064 | ||
| CCND1 (cyclin D1) interacts with CDK4. | BIND | 8662825 | ||
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 8259215 |9837900 |10580009 |11360184 | ||
| CDK4 | CCND2 | CCND2 interacts with CDK4 | BIND | 11291051 |
| - | HPRD,BioGRID | 11358847 | ||
| CDK4 | RB1 | CDK4 phosphorylates Rb carboxy-terminus. This interaction was modelled on a demonstrated interaction between human Rb and mouse CDK4. | BIND | 15241418 |
| CDK4 | ORC3L | - | HPRD | 15232106 |
| CDK4 | GEMIN4 | Affinity Capture-MS | BioGRID | 17353931 |
| CDK4 | BRCA1 | - | HPRD,BioGRID | 9244350 |
| BRCA1 associates with CDK4 | BIND | 9244350 | ||
| CDK4 | SETDB1 | Two-hybrid | BioGRID | 16169070 |
| CDK4 | SMC1A | Affinity Capture-MS | BioGRID | 17353931 |
| CDK4 | BRCA1 | - | HPRD,BioGRID | 9244350 |
| BRCA1 associates with CDK4 | BIND | 9244350 | ||
| CDK4 | CDKN2A | p16 interacts with cdk4. This interaction was modeled on a demonstrated interaction between human p16 and cdk4 from an unspecified species. | BIND | 9482104 |
| CDKN2A interacts with CDK4 | BIND | 11556834 | ||
| - | HPRD,BioGRID | 9228064 | ||
| - | HPRD | 9228064 |15232106 | ||
| p16 interacts with CDK4. This interaction was modeled on a demonstrated interaction between human p16 and CDK4 from an unspecified species. | BIND | 10491434 | ||
| p16 interacts with cdk4. | BIND | 8805225 | ||
| CDK4 | MYC | MYC (c-Myc) interacts with CDK4 promoter. | BIND | 12857727 |
| CDK4 | CCND2 | CCND2 interacts with CDK4 | BIND | 11291051 |
| - | HPRD,BioGRID | 11358847 | ||
| CDK4 | MYOD1 | - | HPRD,BioGRID | 10022835 |10601020 |
| CDK4 | CDKN1B | - | HPRD,BioGRID | 10908655 |
| CDK4 | IFI27 | - | HPRD | 9837900 |
| CDK4 | CDC37 | - | HPRD,BioGRID | 8666233 |8703009 |
| CDK4 | CDKN2A | p16 interacts with cdk4. This interaction was modeled on a demonstrated interaction between human p16 and cdk4 from an unspecified species. | BIND | 9482104 |
| CDKN2A interacts with CDK4 | BIND | 11556834 | ||
| - | HPRD,BioGRID | 9228064 | ||
| - | HPRD | 9228064 |15232106 | ||
| p16 interacts with CDK4. This interaction was modeled on a demonstrated interaction between human p16 and CDK4 from an unspecified species. | BIND | 10491434 | ||
| p16 interacts with cdk4. | BIND | 8805225 | ||
| CDK4 | PSMD10 | - | HPRD,BioGRID | 11779854 |
| CDK4 | CDKN2A | p16 interacts with cdk4. This interaction was modeled on a demonstrated interaction between human p16 and cdk4 from an unspecified species. | BIND | 9482104 |
| CDKN2A interacts with CDK4 | BIND | 11556834 | ||
| - | HPRD,BioGRID | 9228064 | ||
| - | HPRD | 9228064 |15232106 | ||
| p16 interacts with CDK4. This interaction was modeled on a demonstrated interaction between human p16 and CDK4 from an unspecified species. | BIND | 10491434 | ||
| p16 interacts with cdk4. | BIND | 8805225 | ||
| CDK4 | PCNA | Affinity Capture-Western | BioGRID | 8259215 |
| CDK4 | CCND3 | - | HPRD,BioGRID | 10342870 |
| CDK4 | DBNL | Affinity Capture-MS | BioGRID | 17353931 |
| CDK4 | SMC3 | Affinity Capture-MS | BioGRID | 17353931 |
| CDK4 | CDKN2B | - | HPRD | 7478582 |9111314 |9163429 |
| in vitro; in vivo; Two-hybrid | BioGRID | 9163429 |16169070 |16189514 | ||
| CDK4 | PTMA | - | HPRD | 11310559 |
| CDK4 | BIRC5 | - | HPRD,BioGRID | 10713676 |
| CDK4 | CDKN2B | - | HPRD | 7478582 |9111314 |9163429 |
| in vitro; in vivo; Two-hybrid | BioGRID | 9163429 |16169070 |16189514 | ||
| CDK4 | CDKN2C | - | HPRD,BioGRID | 8001816 |
| An unspecified isoform of p18 interacts with cdk4. This interaction was modeled on a demonstrated interaction between human p18 and cdk4 from an unspecified species. | BIND | 9482104 | ||
| CDK4 | UBXN1 | Affinity Capture-MS | BioGRID | 17353931 |
| CDK4 | CCND1 | - | HPRD | 9150368 |9837900 |
| CDK4 interacts with Cyclin D1. This interaction was modelled on a demonstrated interaction between human CDK4 and Cyclin D1 from an unspecified species. | BIND | 9228064 | ||
| CCND1 (cyclin D1) interacts with CDK4. | BIND | 8662825 | ||
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 8259215 |9837900 |10580009 |11360184 | ||
| CDK4 | CDKN2A | p16 interacts with cdk4. This interaction was modeled on a demonstrated interaction between human p16 and cdk4 from an unspecified species. | BIND | 9482104 |
| CDKN2A interacts with CDK4 | BIND | 11556834 | ||
| - | HPRD,BioGRID | 9228064 | ||
| - | HPRD | 9228064 |15232106 | ||
| p16 interacts with CDK4. This interaction was modeled on a demonstrated interaction between human p16 and CDK4 from an unspecified species. | BIND | 10491434 | ||
| p16 interacts with cdk4. | BIND | 8805225 | ||
| CDK4 | CCND1 | - | HPRD | 9150368 |9837900 |
| CDK4 interacts with Cyclin D1. This interaction was modelled on a demonstrated interaction between human CDK4 and Cyclin D1 from an unspecified species. | BIND | 9228064 | ||
| CCND1 (cyclin D1) interacts with CDK4. | BIND | 8662825 | ||
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 8259215 |9837900 |10580009 |11360184 | ||
| CDK4 | SMAD3 | CDK4 phosphorylates Smad3 on Thr8, Thr179, Ser204, Ser208 and Ser213. This interaction was modelled on a demonstrated interaction between Smad3 from an unspecified species and mouse CDK4. | BIND | 15241418 |
| CDK4 | SERTAD1 | - | HPRD,BioGRID | 10580009 |15065884 |
| CDK4 | CCND1 | - | HPRD | 9150368 |9837900 |
| CDK4 interacts with Cyclin D1. This interaction was modelled on a demonstrated interaction between human CDK4 and Cyclin D1 from an unspecified species. | BIND | 9228064 | ||
| CCND1 (cyclin D1) interacts with CDK4. | BIND | 8662825 | ||
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 8259215 |9837900 |10580009 |11360184 | ||
| CDK4 | CDC7 | - | HPRD | 15232106 |
| CDK4 | CAPNS1 | Two-hybrid | BioGRID | 16169070 |
| CDK4 | LYN | Affinity Capture-MS | BioGRID | 17353931 |
| CDK4 | CDKN2A | p16 interacts with cdk4. This interaction was modeled on a demonstrated interaction between human p16 and cdk4 from an unspecified species. | BIND | 9482104 |
| CDKN2A interacts with CDK4 | BIND | 11556834 | ||
| - | HPRD,BioGRID | 9228064 | ||
| - | HPRD | 9228064 |15232106 | ||
| p16 interacts with CDK4. This interaction was modeled on a demonstrated interaction between human p16 and CDK4 from an unspecified species. | BIND | 10491434 | ||
| p16 interacts with cdk4. | BIND | 8805225 | ||
| CDK4 | CDKN1A | Cdk4 interacts with p21. | BIND | 8999999 |
| CDK4 | CEBPA | - | HPRD,BioGRID | 11684017 |
| CDK4 | CDKN2C | - | HPRD,BioGRID | 8001816 |
| An unspecified isoform of p18 interacts with cdk4. This interaction was modeled on a demonstrated interaction between human p18 and cdk4 from an unspecified species. | BIND | 9482104 | ||
| CDK4 | SMAD2 | CDK4 phosphorylates Smad2. This interaction was modelled on a demonstrated interaction between Smad2 from an unspecified species and mouse CDK4. | BIND | 15241418 |
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