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Protein-protein interaction for MAP2K4
 Nodes,
degree=1 |
 Nodes,
degree=2 |
Protein-protein interaction data for gene MAP2K4
| Degree = 1 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| MAP2K4 | MAP3K1 | MKK4 interacts with MEKK1. This interaction was modeled on a demonstrated interaction between human MKK4 and rat MEKK1. | BIND | 15866172 |
| MEKK1 phosphorylates MEK4. | BIND | 10969079 | ||
| MAP2K4 | MAP3K4 | - | HPRD,BioGRID | 9841871 |
| MKK4 interacts with and is phosphorylated by MTK1. | BIND | 15866172 | ||
| MAP2K4 | MAPK14 | - | HPRD,BioGRID | 7716521 |
| MAP2K4 | MAP3K8 | - | HPRD,BioGRID | 8631303 |
| MAP2K4 | MAP3K7 | - | HPRD | 12556533 |
| MAP2K4 | MAPK8 | - | HPRD | 9661668 |11062067 |
| MKK4 phosphorylates JNK1. This interaction was modeled on a demonstrated interaction between MKK4 from an unspecified species and JNK1 from an unpsecified species. | BIND | 12659851 | ||
| Biochemical Activity; Phenotypic Enhancement; Reconstituted Complex | BioGRID | 9207092 |11279118 |11707464 |12391307 | ||
| MAP2K4 | AKT1 | - | HPRD,BioGRID | 11707464 |
| MAP2K4 | MAP3K11 | Biochemical Activity | BioGRID | 10187804 |
| MAP2K4 | MAPK8IP3 | - | HPRD,BioGRID | 10523642 |12189133 |
| - | HPRD | 12189133 | ||
| MAP2K4 | DUSP22 | - | HPRD | 11346645 |
| MAP2K4 | ZAK | - | HPRD | 11836244 |
| MAP2K4 | MAP4K2 | Reconstituted Complex | BioGRID | 9712898 |
| MAP2K4 | FLNC | - | HPRD,BioGRID | 9006895 |
| MAP2K4 | MAP3K12 | - | HPRD | 10187804 |
| MAP2K4 | MAP3K2 | - | HPRD | 7997270 |
| MAP2K4 | FLNA | - | HPRD | 9006895 |
| MAP2K4 | SPAG9 | - | HPRD,BioGRID | 12391307 |
| MAP2K4 | ARRB2 | - | HPRD,BioGRID | 11090355 |
| MAP2K4 | MAP2K7 | Phenotypic Enhancement | BioGRID | 11062067 |
| MAP2K4 | MAP3K10 | - | HPRD,BioGRID | 9182538 |
| Degree = 2 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| MAP3K1 | HSP90AA2 | Affinity Capture-MS | BioGRID | 14743216 |
| MAP3K1 | MAPK3 | MEKK1 interacts with ERK1. | BIND | 12049732 |
| MAP3K1 | DVL2 | Affinity Capture-Western | BioGRID | 10829020 |
| MAP3K1 | ECSIT | in vivo | BioGRID | 10465784 |
| MAP3K1 | RPL4 | Affinity Capture-MS | BioGRID | 14743216 |
| MAP3K1 | MAP2K1 | Affinity Capture-Western | BioGRID | 10969079 |
| MEKK1 interacts with MEK1. | BIND | 10969079 | ||
| MAP3K1 | PAK3 | in vivo | BioGRID | 9065412 |
| MAP3K1 | GRB2 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 9733714 |
| MAP3K1 | MAPK1 | Affinity Capture-Western | BioGRID | 10969079 |
| MEKK1 interacts with ERK2. | BIND | 10969079 | ||
| MAP3K1 | RPS13 | Affinity Capture-MS | BioGRID | 14743216 |
| MAP3K1 | CDC37 | Affinity Capture-MS | BioGRID | 14743216 |
| MAP3K1 | AXIN1 | Affinity Capture-Western | BioGRID | 10829020 |11884395 |
| MAP3K1 | TRAF2 | Affinity Capture-Western; Co-fractionation | BioGRID | 10346818 |
| MAP3K1 | RAF1 | MEKK1 interacts with Raf-1. | BIND | 10969079 |
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 10969079 | ||
| MAP3K1 | CD82 | MAP3K1 (MEKK1) interacts with the CD82 (KAI1) promoter. | BIND | 15829968 |
| MAP3K1 | MAP2K1 | Affinity Capture-Western | BioGRID | 10969079 |
| MEKK1 interacts with MEK1. | BIND | 10969079 | ||
| MAP3K1 | RPL30 | Affinity Capture-MS | BioGRID | 14743216 |
| MAP3K1 | RAF1 | MEKK1 interacts with Raf-1. | BIND | 10969079 |
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 10969079 | ||
| MAP3K1 | FKBP5 | Affinity Capture-MS | BioGRID | 14743216 |
| MAP3K1 | MAP4K4 | Affinity Capture-Western | BioGRID | 9135144 |
| MAP3K1 | YWHAE | Reconstituted Complex | BioGRID | 9452471 |
| MAP3K1 | UBE2I | Reconstituted Complex; Two-hybrid | BioGRID | 9563508 |
| MAP3K1 | WDR68 | Affinity Capture-MS | BioGRID | 14743216 |
| MAP3K1 | MAPK1 | Affinity Capture-Western | BioGRID | 10969079 |
| MEKK1 interacts with ERK2. | BIND | 10969079 | ||
| MAP3K4 | DIXDC1 | - | HPRD | 15262978 |
| MAP3K4 | RACGAP1 | - | HPRD | 9079650 |
| MAP3K4 | GADD45A | - | HPRD,BioGRID | 9827804 |11498536 |
| MAP3K4 | MAP2K1 | - | HPRD,BioGRID | 9841871 |
| MAP3K4 | CDC42 | - | HPRD,BioGRID | 9079650 |
| MAP3K4 | RAC1 | Reconstituted Complex | BioGRID | 9079650 |
| MAP3K4 | MAP2K3 | - | HPRD,BioGRID | 9841871 |
| MKK3 interacts with MTK1. | BIND | 15866172 | ||
| MAP3K4 | MAP2K6 | MKK6 interacts with and is phosphorylated by MTK1. | BIND | 15866172 |
| - | HPRD,BioGRID | 9841871 | ||
| MAP3K4 | MAP2K3 | - | HPRD,BioGRID | 9841871 |
| MKK3 interacts with MTK1. | BIND | 15866172 | ||
| MAP3K4 | GADD45G | - | HPRD,BioGRID | 9827804 |
| MAP3K4 | GADD45B | - | HPRD,BioGRID | 9827804 |
| MAP3K4 | MAP2K6 | MKK6 interacts with and is phosphorylated by MTK1. | BIND | 15866172 |
| - | HPRD,BioGRID | 9841871 | ||
| MAPK14 | CDC25B | Biochemical Activity; Reconstituted Complex | BioGRID | 11333986 |
| p38-alpha interacts with and phosphorylates CDC25B. | BIND | 15629715 | ||
| MAPK14 | MAP2K3 | - | HPRD | 7839144|8622669 |
| Biochemical Activity | BioGRID | 11279118 | ||
| MKK3 phosphorylates an unspecified isoform of p38. This interaction was modeled on a demonstrated interaction between human MKK3 and p38 from an unspecified species. | BIND | 8622669 | ||
| MAPK14 | CREB1 | - | HPRD,BioGRID | 11377386 |
| MAPK14 | PTPN7 | - | HPRD | 10559944 |
| MAPK14 | SCYE1 | - | HPRD | 9878398 |
| MAPK14 | DUSP10 | Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid | BioGRID | 10391943 |11157753 |11359773 |
| An unspecified isoform of MAPK14 interacts with DUSP10. | BIND | 10391943 | ||
| - | HPRD | 10391943 |10597297 |11359773 | ||
| MAPK14 | MAPKAPK3 | - | HPRD,BioGRID | 11157753 |
| MAPK14 | CDC25A | Reconstituted Complex | BioGRID | 12963847 |
| MAPK14 | SLC44A1 | - | HPRD | 9707433 |
| MAPK14 | HTRA2 | - | HPRD,BioGRID | 10644717 |
| MAPK14 | CDC25C | - | HPRD,BioGRID | 11333986 |
| MAPK14 | GRB2 | - | HPRD | 8695800 |
| MAPK14 | MAPK1 | - | HPRD,BioGRID | 12697810 |
| MAPK14 | GMFB | - | HPRD,BioGRID | 8798479 |
| MAPK14 | CSNK2B | - | HPRD | 10747897 |
| MAPK14 | JUN | An unspecified isoform of p38 interacts with and phosphorylates c-Jun. | BIND | 9155018 |
| MAPK14 | RPS6KA3 | Affinity Capture-Western | BioGRID | 11157753 |
| MAPK14 | MAPK3 | - | HPRD,BioGRID | 12697810 |
| MAPK14 | CSNK2A1 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 10747897 |
| MAPK14 | DUSP10 | Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid | BioGRID | 10391943 |11157753 |11359773 |
| An unspecified isoform of MAPK14 interacts with DUSP10. | BIND | 10391943 | ||
| - | HPRD | 10391943 |10597297 |11359773 | ||
| MAPK14 | KRT18 | - | HPRD,BioGRID | 11788583 |
| MAPK14 | MKNK1 | - | HPRD | 9155018 |
| Affinity Capture-Western | BioGRID | 11157753 | ||
| An unspecified isoform of p38 interacts with and phosphorylates MNK1. | BIND | 9155018 | ||
| MAPK14 | DUSP16 | - | HPRD,BioGRID | 11359773 |11489891 |14586399 |
| MAPK14 | DUSP2 | - | HPRD | 7535770 |
| MAPK14 | STK39 | - | HPRD | 10980603 |
| Affinity Capture-Western | BioGRID | 14563843 | ||
| MAPK14 | DDIT3 | - | HPRD,BioGRID | 8650547 |
| MAPK14 | NCF1C | p38-alpha interacts with and phosphorylates p47phox. | BIND | 15629715 |
| MAPK14 | ATF2 | An unspecified isoform of p38 interacts with and phosphorylates ATF2. | BIND | 9155018 |
| An unspecified isoform of p38 interacts with and phosphorylates ATF2. | BIND | 9235954 | ||
| p38 phosphorylates ATF2. This interaction was modelled on a demonstrated interaction between human p38 and ATF2 from an unspecified species. | BIND | 15692053 | ||
| - | HPRD,BioGRID | 7535770 | ||
| MAPK14 | PLCB2 | Affinity Capture-Western | BioGRID | 12054652 |
| MAPK14 | MKNK1 | - | HPRD | 9155018 |
| Affinity Capture-Western | BioGRID | 11157753 | ||
| An unspecified isoform of p38 interacts with and phosphorylates MNK1. | BIND | 9155018 | ||
| MAPK14 | ELK1 | Elk-1 is phosphorylated by an unspecified isoform of p38 MAPK. This interaction was modeled on a demonstrated interaction between human Elk-1 and p38 MAPK from an unspecified species. | BIND | 9130707 |
| - | HPRD | 8622669 | ||
| An unspecified isoform of p38 interacts with and phosphorylates Elk-1. | BIND | 9155018 | ||
| MAPK14 | MKNK2 | - | HPRD | 12897141 |
| MAPK14 | CSNK2A2 | - | HPRD | 10747897 |
| MAPK14 | MAP2K3 | - | HPRD | 7839144|8622669 |
| Biochemical Activity | BioGRID | 11279118 | ||
| MKK3 phosphorylates an unspecified isoform of p38. This interaction was modeled on a demonstrated interaction between human MKK3 and p38 from an unspecified species. | BIND | 8622669 | ||
| MAPK14 | KARS | Two-hybrid | BioGRID | 12819782 |
| MAPK14 | MAPKAPK2 | - | HPRD,BioGRID | 9768359 |11042204 |11551945 |
| MAPK14 | PML | - | HPRD | 15273249 |
| MAPK14 | ETV1 | Biochemical Activity | BioGRID | 11551945 |
| MAPK14 | MAP3K7IP1 | TAB1 interacts with an unspecified isoform of p38. | BIND | 12829618 |
| - | HPRD,BioGRID | 11847341 | ||
| MAPK14 | DYRK1B | - | HPRD,BioGRID | 10910078 |
| MAPK14 | MAP2K1 | - | HPRD | 12697810 |
| MAPK14 | ELK4 | An unspecified isoform of p38 interacts with and phosphorylates Sap-1a. | BIND | 9235954 |
| Sap-1a is phosphorylated by an unspecified isoform of p38 MAPK. This interaction was modeled on a demonstrated interaction between human Sap-1a and p38 MAPK from an unspecified species. | BIND | 9130707 | ||
| MAPK14 | ELK4 | An unspecified isoform of p38 interacts with and phosphorylates Sap-1a. | BIND | 9235954 |
| Sap-1a is phosphorylated by an unspecified isoform of p38 MAPK. This interaction was modeled on a demonstrated interaction between human Sap-1a and p38 MAPK from an unspecified species. | BIND | 9130707 | ||
| MAPK14 | RPS6KA5 | Affinity Capture-Western | BioGRID | 11157753 |
| MAPK14 | MAP2K6 | - | HPRD,BioGRID | 8626699 |
| MAPK14 | EGFR | Biochemical Activity | BioGRID | 7535770 |
| MAPK14 | MAP3K7IP1 | TAB1 interacts with an unspecified isoform of p38. | BIND | 12829618 |
| - | HPRD,BioGRID | 11847341 | ||
| MAPK14 | MKNK1 | - | HPRD | 9155018 |
| Affinity Capture-Western | BioGRID | 11157753 | ||
| An unspecified isoform of p38 interacts with and phosphorylates MNK1. | BIND | 9155018 | ||
| MAPK14 | FUBP1 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 12819782 |
| MAPK14 | DUSP6 | Affinity Capture-Western | BioGRID | 11359773 |
| MAPK14 | MAP2K3 | - | HPRD | 7839144|8622669 |
| Biochemical Activity | BioGRID | 11279118 | ||
| MKK3 phosphorylates an unspecified isoform of p38. This interaction was modeled on a demonstrated interaction between human MKK3 and p38 from an unspecified species. | BIND | 8622669 | ||
| MAPK14 | MEF2C | - | HPRD | 9753748 |10330143 |
| MAPK14 | ELK1 | Elk-1 is phosphorylated by an unspecified isoform of p38 MAPK. This interaction was modeled on a demonstrated interaction between human Elk-1 and p38 MAPK from an unspecified species. | BIND | 9130707 |
| - | HPRD | 8622669 | ||
| An unspecified isoform of p38 interacts with and phosphorylates Elk-1. | BIND | 9155018 | ||
| MAPK14 | CDC25B | Biochemical Activity; Reconstituted Complex | BioGRID | 11333986 |
| p38-alpha interacts with and phosphorylates CDC25B. | BIND | 15629715 | ||
| MAPK14 | STK39 | - | HPRD | 10980603 |
| Affinity Capture-Western | BioGRID | 14563843 | ||
| MAPK14 | DUSP1 | - | HPRD | 7535770 |
| Affinity Capture-Western; Two-hybrid | BioGRID | 11278799 |11359773 | ||
| MAPK14 | SLC12A2 | Affinity Capture-Western | BioGRID | 14563843 |
| MAPK14 | DUSP10 | Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid | BioGRID | 10391943 |11157753 |11359773 |
| An unspecified isoform of MAPK14 interacts with DUSP10. | BIND | 10391943 | ||
| - | HPRD | 10391943 |10597297 |11359773 | ||
| MAPK14 | ZFP36L1 | Affinity Capture-Western; Two-hybrid | BioGRID | 16189514 |
| MAPK14 | RPS6KA4 | - | HPRD,BioGRID | 9792677 |
| MAPK14 | DUSP4 | - | HPRD,BioGRID | 11387337 |
| MAPK14 | ELK1 | Elk-1 is phosphorylated by an unspecified isoform of p38 MAPK. This interaction was modeled on a demonstrated interaction between human Elk-1 and p38 MAPK from an unspecified species. | BIND | 9130707 |
| - | HPRD | 8622669 | ||
| An unspecified isoform of p38 interacts with and phosphorylates Elk-1. | BIND | 9155018 | ||
| MAPK14 | ATF2 | An unspecified isoform of p38 interacts with and phosphorylates ATF2. | BIND | 9155018 |
| An unspecified isoform of p38 interacts with and phosphorylates ATF2. | BIND | 9235954 | ||
| p38 phosphorylates ATF2. This interaction was modelled on a demonstrated interaction between human p38 and ATF2 from an unspecified species. | BIND | 15692053 | ||
| - | HPRD,BioGRID | 7535770 | ||
| MAPK14 | MEF2A | - | HPRD,BioGRID | 10330143 |
| MAPK14 | MARS | - | HPRD | 9878398 |
| MAPK14 | DUSP1 | - | HPRD | 7535770 |
| Affinity Capture-Western; Two-hybrid | BioGRID | 11278799 |11359773 | ||
| MAPK14 | ATF2 | An unspecified isoform of p38 interacts with and phosphorylates ATF2. | BIND | 9155018 |
| An unspecified isoform of p38 interacts with and phosphorylates ATF2. | BIND | 9235954 | ||
| p38 phosphorylates ATF2. This interaction was modelled on a demonstrated interaction between human p38 and ATF2 from an unspecified species. | BIND | 15692053 | ||
| - | HPRD,BioGRID | 7535770 | ||
| MAPK14 | SMAD7 | - | HPRD,BioGRID | 12589052 |
| MAPK14 | ATF2 | An unspecified isoform of p38 interacts with and phosphorylates ATF2. | BIND | 9155018 |
| An unspecified isoform of p38 interacts with and phosphorylates ATF2. | BIND | 9235954 | ||
| p38 phosphorylates ATF2. This interaction was modelled on a demonstrated interaction between human p38 and ATF2 from an unspecified species. | BIND | 15692053 | ||
| - | HPRD,BioGRID | 7535770 | ||
| MAP3K8 | TNIP2 | - | HPRD,BioGRID | 14743216 |15169888 |
| MAP3K8 | MAP2K1 | Biochemical Activity | BioGRID | 8631303 |
| MAP3K8 | KSR2 | Affinity Capture-Western | BioGRID | 12975377 |
| MAP3K8 | REL | Affinity Capture-MS | BioGRID | 14743216 |
| MAP3K8 | RELA | Affinity Capture-MS | BioGRID | 14743216 |
| MAP3K8 | NFKB2 | Affinity Capture-MS | BioGRID | 14743216 |
| MAP3K8 | NFKB1 | - | HPRD,BioGRID | 9950430 |
| MAP3K8 | CHUK | - | HPRD,BioGRID | 10072079 |
| MAP3K8 | MAP3K14 | - | HPRD,BioGRID | 10072079 |
| MAP3K8 | TRAF2 | - | HPRD,BioGRID | 11932422 |
| MAP3K7 | RPLP0 | - | HPRD | 14743216 |
| MAP3K7 | PELI3 | - | HPRD | 12874243 |
| MAP3K7 | TRAF6 | - | HPRD,BioGRID | 10094049 |
| MAP3K7 | TUBB2B | - | HPRD | 14743216 |
| MAP3K7 | TRAF3IP2 | - | HPRD | 12089335 |
| MAP3K7 | ENO1 | - | HPRD | 14743216 |
| MAP3K7 | FOS | - | HPRD | 11397816 |
| MAP3K7 | MAP3K7IP2 | - | HPRD,BioGRID | 11259596 |
| - | HPRD | 11259596 |14743216 | ||
| MAP3K7 | NRIP1 | - | HPRD | 9556573 |
| MAP3K7 | PPM1B | - | HPRD,BioGRID | 11104763 |
| MAP3K7 | MAP3K7IP2 | - | HPRD,BioGRID | 11259596 |
| - | HPRD | 11259596 |14743216 | ||
| MAP3K7 | CLTC | - | HPRD | 14743216 |
| MAP3K7 | XIAP | - | HPRD,BioGRID | 12048196 |
| MAP3K7 | SMAD6 | - | HPRD,BioGRID | 10748100 |
| MAP3K7 | PEBP1 | - | HPRD,BioGRID | 11585904 |
| MAP3K7 | RPS3 | - | HPRD | 14743216 |
| MAP3K7 | HSPA1B | - | HPRD | 14743216 |
| MAP3K7 | TUBB4 | - | HPRD | 14743216 |
| MAP3K7 | HSPA5 | - | HPRD | 14743216 |
| MAP3K7 | MAP4K4 | - | HPRD,BioGRID | 10807933 |
| MAP3K7 | HIST1H4I | - | HPRD | 14743216 |
| MAP3K7 | HSPA1L | - | HPRD | 14743216 |
| MAP3K7 | MAP4K1 | - | HPRD,BioGRID | 10224067 |
| MAP3K7 | E2F4 | E2F4 interacts with MAP3K7 promoter. | BIND | 15782160 |
| MAP3K7 | TRAF2 | Affinity Capture-Western | BioGRID | 14633987 |
| - | HPRD | 14743216 | ||
| MAP3K7 | NUDT21 | - | HPRD | 14743216 |
| MAP3K7 | MAP3K5 | - | HPRD,BioGRID | 10921914 |
| MAP3K7 | MAP3K7IP1 | - | HPRD,BioGRID | 10838074 |
| An unspecified isoform of TAK1 interacts with TAB1. This interaction was modeled on a demonstrated interaction between TAK1 from an unspecified species and human TAB1. | BIND | 9878061 | ||
| - | HPRD | 10838074|14743216 | ||
| MAP3K7 | HGS | - | HPRD,BioGRID | 11397816 |
| MAP3K7 | NAIP | - | HPRD | 11865055 |
| MAP3K7 | DARS | - | HPRD | 14743216 |
| MAP3K7 | RUVBL2 | - | HPRD | 14743216 |
| MAP3K7 | MAP2K6 | - | HPRD,BioGRID | 11460167 |
| MAP3K7 | TRAF2 | Affinity Capture-Western | BioGRID | 14633987 |
| - | HPRD | 14743216 | ||
| MAP3K7 | HSPA9 | - | HPRD | 14743216 |
| MAP3K7 | MAP3K14 | - | HPRD,BioGRID | 10094049 |
| MAP3K7 | DNAJA1 | - | HPRD | 14743216 |
| MAP3K7 | FKBP5 | - | HPRD | 14743216 |
| MAP3K7 | IARS | - | HPRD | 14743216 |
| MAP3K7 | TNFRSF11A | - | HPRD,BioGRID | 11809792 |
| MAP3K7 | CDC37 | - | HPRD | 14743216 |
| MAP3K7 | CALM3 | - | HPRD | 14743216 |
| MAP3K7 | EPRS | - | HPRD | 14743216 |
| MAP3K7 | HSP90AA1 | - | HPRD | 14743216 |
| MAP3K7 | RUVBL1 | - | HPRD | 14743216 |
| MAP3K7 | PPM1L | - | HPRD | 12556533 |
| MAP3K7 | MAP3K7IP3 | Affinity Capture-Western | BioGRID | 14633987 |14670075 |
| MAP3K7 | DDX5 | - | HPRD | 14743216 |
| MAP3K7 | CHUK | - | HPRD,BioGRID | 10187861 |
| MAP3K7 | SMAD7 | - | HPRD,BioGRID | 12589052 |
| MAP3K7 | ACTG1 | - | HPRD | 14743216 |
| MAP3K7 | TUBB2A | - | HPRD | 14743216 |
| MAP3K7 | MAP3K7IP1 | - | HPRD,BioGRID | 10838074 |
| An unspecified isoform of TAK1 interacts with TAB1. This interaction was modeled on a demonstrated interaction between TAK1 from an unspecified species and human TAB1. | BIND | 9878061 | ||
| - | HPRD | 10838074|14743216 | ||
| MAP3K7 | HSPA8 | - | HPRD | 14743216 |
| MAP3K7 | CAD | - | HPRD | 14743216 |
| MAP3K7 | MAP3K7IP1 | - | HPRD,BioGRID | 10838074 |
| An unspecified isoform of TAK1 interacts with TAB1. This interaction was modeled on a demonstrated interaction between TAK1 from an unspecified species and human TAB1. | BIND | 9878061 | ||
| - | HPRD | 10838074|14743216 | ||
| MAP3K7 | TUBA3C | - | HPRD | 14743216 |
| MAP3K7 | STRADB | - | HPRD,BioGRID | 12048196 |
| MAP3K7 | HSP90AB1 | - | HPRD | 14743216 |
| MAP3K7 | EEF1A1 | - | HPRD | 14743216 |
| MAPK8 | JUN | - | HPRD,BioGRID | 8137421 |
| JNK1 phosphorylates c-Jun. This interaction was modeled on a demonstrated interaction between bovine JNK1 or JNK1 from an unspecified species, and c-Jun from an unspecified species. | BIND | 9374537 | ||
| JNK1beta2 interacts with c-Jun. | BIND | 12167088 | ||
| c-Jun is phosphorylated by JNK-1. This interaction was modeled on a demonstrated interaction between c-Jun and JNK-1, both from an unspecified species. | BIND | 9020136 | ||
| JNK1beta1 interacts with c-Jun. | BIND | 12167088 | ||
| JNK1alpha1 interacts with c-Jun. | BIND | 12167088 | ||
| MAPK8 (JNK1) phosphorylates JUN (c-Jun) | BIND | 16007099 | ||
| JNK1alpha2 interacts with c-Jun. | BIND | 12167088 | ||
| MAPK8 | JUN | - | HPRD,BioGRID | 8137421 |
| JNK1 phosphorylates c-Jun. This interaction was modeled on a demonstrated interaction between bovine JNK1 or JNK1 from an unspecified species, and c-Jun from an unspecified species. | BIND | 9374537 | ||
| JNK1beta2 interacts with c-Jun. | BIND | 12167088 | ||
| c-Jun is phosphorylated by JNK-1. This interaction was modeled on a demonstrated interaction between c-Jun and JNK-1, both from an unspecified species. | BIND | 9020136 | ||
| JNK1beta1 interacts with c-Jun. | BIND | 12167088 | ||
| JNK1alpha1 interacts with c-Jun. | BIND | 12167088 | ||
| MAPK8 (JNK1) phosphorylates JUN (c-Jun) | BIND | 16007099 | ||
| JNK1alpha2 interacts with c-Jun. | BIND | 12167088 | ||
| MAPK8 | JUNB | - | HPRD,BioGRID | 9405416 |
| MAPK8 | MAPK8IP2 | - | HPRD | 10756100 |
| MAPK8 | SH3BP5 | Sab interacts with JNK1-alpha-2. | BIND | 12167088 |
| Sab interacts with JNK1-alpha-1. | BIND | 12167088 | ||
| - | HPRD,BioGRID | 12167088 | ||
| Sab interacts with JNK1-beta-2. | BIND | 12167088 | ||
| Sab interacts with JNK1-beta-1. | BIND | 12167088 | ||
| MAPK8 | MAP1B | - | HPRD | 12689591 |
| MAPK8 | DUSP16 | - | HPRD,BioGRID | 11489891 |
| MAPK8 | ETV1 | Biochemical Activity | BioGRID | 11551945 |
| MAPK8 | BID | Co-purification | BioGRID | 15659383 |
| MAPK8 | SPI1 | Biochemical Activity | BioGRID | 8632909 |
| MAPK8 | JUN | - | HPRD,BioGRID | 8137421 |
| JNK1 phosphorylates c-Jun. This interaction was modeled on a demonstrated interaction between bovine JNK1 or JNK1 from an unspecified species, and c-Jun from an unspecified species. | BIND | 9374537 | ||
| JNK1beta2 interacts with c-Jun. | BIND | 12167088 | ||
| c-Jun is phosphorylated by JNK-1. This interaction was modeled on a demonstrated interaction between c-Jun and JNK-1, both from an unspecified species. | BIND | 9020136 | ||
| JNK1beta1 interacts with c-Jun. | BIND | 12167088 | ||
| JNK1alpha1 interacts with c-Jun. | BIND | 12167088 | ||
| MAPK8 (JNK1) phosphorylates JUN (c-Jun) | BIND | 16007099 | ||
| JNK1alpha2 interacts with c-Jun. | BIND | 12167088 | ||
| MAPK8 | CRK | - | HPRD,BioGRID | 11432831 |
| MAPK8 | REL | - | HPRD,BioGRID | 8621542 |
| MAPK8 | IRS1 | - | HPRD,BioGRID | 10722755 |11606564 |12417588 |
| MAPK8 | SH3BP5 | Sab interacts with JNK1-alpha-2. | BIND | 12167088 |
| Sab interacts with JNK1-alpha-1. | BIND | 12167088 | ||
| - | HPRD,BioGRID | 12167088 | ||
| Sab interacts with JNK1-beta-2. | BIND | 12167088 | ||
| Sab interacts with JNK1-beta-1. | BIND | 12167088 | ||
| MAPK8 | JUN | - | HPRD,BioGRID | 8137421 |
| JNK1 phosphorylates c-Jun. This interaction was modeled on a demonstrated interaction between bovine JNK1 or JNK1 from an unspecified species, and c-Jun from an unspecified species. | BIND | 9374537 | ||
| JNK1beta2 interacts with c-Jun. | BIND | 12167088 | ||
| c-Jun is phosphorylated by JNK-1. This interaction was modeled on a demonstrated interaction between c-Jun and JNK-1, both from an unspecified species. | BIND | 9020136 | ||
| JNK1beta1 interacts with c-Jun. | BIND | 12167088 | ||
| JNK1alpha1 interacts with c-Jun. | BIND | 12167088 | ||
| MAPK8 (JNK1) phosphorylates JUN (c-Jun) | BIND | 16007099 | ||
| JNK1alpha2 interacts with c-Jun. | BIND | 12167088 | ||
| MAPK8 | SH3BP5 | Sab interacts with JNK1-alpha-2. | BIND | 12167088 |
| Sab interacts with JNK1-alpha-1. | BIND | 12167088 | ||
| - | HPRD,BioGRID | 12167088 | ||
| Sab interacts with JNK1-beta-2. | BIND | 12167088 | ||
| Sab interacts with JNK1-beta-1. | BIND | 12167088 | ||
| MAPK8 | MSN | Co-purification | BioGRID | 15659383 |
| MAPK8 | MAPK8IP1 | - | HPRD,BioGRID | 9733513 |
| MAPK8 | ELK1 | An unspecified isoform of JNK1 interacts with and phosphorylates Elk1. | BIND | 9235954 |
| Biochemical Activity | BioGRID | 8586671 | ||
| Elk-1 is phosphorylated by JNK-1. This interaction was modeled on a demonstrated interaction between human Elk-1 and JNK-1 from an unspecified species. | BIND | 9020136 | ||
| MAPK8 | SNCG | - | HPRD,BioGRID | 12121974 |
| MAPK8 | JUN | - | HPRD,BioGRID | 8137421 |
| JNK1 phosphorylates c-Jun. This interaction was modeled on a demonstrated interaction between bovine JNK1 or JNK1 from an unspecified species, and c-Jun from an unspecified species. | BIND | 9374537 | ||
| JNK1beta2 interacts with c-Jun. | BIND | 12167088 | ||
| c-Jun is phosphorylated by JNK-1. This interaction was modeled on a demonstrated interaction between c-Jun and JNK-1, both from an unspecified species. | BIND | 9020136 | ||
| JNK1beta1 interacts with c-Jun. | BIND | 12167088 | ||
| JNK1alpha1 interacts with c-Jun. | BIND | 12167088 | ||
| MAPK8 (JNK1) phosphorylates JUN (c-Jun) | BIND | 16007099 | ||
| JNK1alpha2 interacts with c-Jun. | BIND | 12167088 | ||
| MAPK8 | CDKN2A | CDKN2A (p16INK4a) interacts with MAPK8 (JNK1) | BIND | 16007099 |
| MAPK8 | TNFRSF1A | Co-purification | BioGRID | 15659383 |
| MAPK8 | JUN | - | HPRD,BioGRID | 8137421 |
| JNK1 phosphorylates c-Jun. This interaction was modeled on a demonstrated interaction between bovine JNK1 or JNK1 from an unspecified species, and c-Jun from an unspecified species. | BIND | 9374537 | ||
| JNK1beta2 interacts with c-Jun. | BIND | 12167088 | ||
| c-Jun is phosphorylated by JNK-1. This interaction was modeled on a demonstrated interaction between c-Jun and JNK-1, both from an unspecified species. | BIND | 9020136 | ||
| JNK1beta1 interacts with c-Jun. | BIND | 12167088 | ||
| JNK1alpha1 interacts with c-Jun. | BIND | 12167088 | ||
| MAPK8 (JNK1) phosphorylates JUN (c-Jun) | BIND | 16007099 | ||
| JNK1alpha2 interacts with c-Jun. | BIND | 12167088 | ||
| MAPK8 | CASP8 | Co-purification | BioGRID | 15659383 |
| MAPK8 | FADD | Co-purification | BioGRID | 15659383 |
| MAPK8 | XRCC6 | - | HPRD | 11749722 |
| MAPK8 | COPS2 | - | HPRD | 10585392 |
| MAPK8 | FASLG | Co-purification | BioGRID | 15659383 |
| MAPK8 | DUSP4 | Reconstituted Complex | BioGRID | 11387337 |
| MAPK8 | ATF2 | Affinity Capture-Western; Biochemical Activity; Reconstituted Complex | BioGRID | 7535770 |9207092 |9405416 |11279118 |
| - | HPRD | 7737129 |7737130 | ||
| MAPK8 | MYC | - | HPRD,BioGRID | 10551811 |
| MAPK8 | WWOX | - | HPRD | 12514174 |
| MAPK8 | IL27RA | - | HPRD | 12734330 |
| MAPK8 | SNCA | Affinity Capture-Western | BioGRID | 12121974 |
| MAPK8 | HRAS | - | HPRD | 8137421 |11525649 |
| MAPK8 | CASP10 | Co-purification | BioGRID | 15659383 |
| MAPK8 | JUN | - | HPRD,BioGRID | 8137421 |
| JNK1 phosphorylates c-Jun. This interaction was modeled on a demonstrated interaction between bovine JNK1 or JNK1 from an unspecified species, and c-Jun from an unspecified species. | BIND | 9374537 | ||
| JNK1beta2 interacts with c-Jun. | BIND | 12167088 | ||
| c-Jun is phosphorylated by JNK-1. This interaction was modeled on a demonstrated interaction between c-Jun and JNK-1, both from an unspecified species. | BIND | 9020136 | ||
| JNK1beta1 interacts with c-Jun. | BIND | 12167088 | ||
| JNK1alpha1 interacts with c-Jun. | BIND | 12167088 | ||
| MAPK8 (JNK1) phosphorylates JUN (c-Jun) | BIND | 16007099 | ||
| JNK1alpha2 interacts with c-Jun. | BIND | 12167088 | ||
| MAPK8 | TNFSF11 | - | HPRD | 9396779 |
| MAPK8 | FAS | Co-purification | BioGRID | 15659383 |
| MAPK8 | DUSP10 | - | HPRD,BioGRID | 10391943 |10597297 |
| An unspecified isoform of MAPK8 interacts with DUSP10. This interaction was modelled on a demonstrated interaction between MAPK8 from an unspecified species and human DUSP10. | BIND | 10391943 | ||
| MAPK8 | PAX2 | - | HPRD,BioGRID | 11700324 |
| MAPK8 | ELK4 | Sap-1a is phosphorylated by stress-activated JNK-1. This interaction was modeled on a demonstrated interaction between human Sap-1a and JNK-1 from an unspecified species. | BIND | 9020136 |
| MAPK8 | PRKD1 | Affinity Capture-Western | BioGRID | 11948398 |
| MAPK8 | ELK1 | An unspecified isoform of JNK1 interacts with and phosphorylates Elk1. | BIND | 9235954 |
| Biochemical Activity | BioGRID | 8586671 | ||
| Elk-1 is phosphorylated by JNK-1. This interaction was modeled on a demonstrated interaction between human Elk-1 and JNK-1 from an unspecified species. | BIND | 9020136 | ||
| MAPK8 | PRKDC | - | HPRD,BioGRID | 11749722 |
| MAPK8 | EZR | Co-purification | BioGRID | 15659383 |
| MAPK8 | SMAD3 | - | HPRD | 10601313 |
| MAPK8 | JUN | - | HPRD,BioGRID | 8137421 |
| JNK1 phosphorylates c-Jun. This interaction was modeled on a demonstrated interaction between bovine JNK1 or JNK1 from an unspecified species, and c-Jun from an unspecified species. | BIND | 9374537 | ||
| JNK1beta2 interacts with c-Jun. | BIND | 12167088 | ||
| c-Jun is phosphorylated by JNK-1. This interaction was modeled on a demonstrated interaction between c-Jun and JNK-1, both from an unspecified species. | BIND | 9020136 | ||
| JNK1beta1 interacts with c-Jun. | BIND | 12167088 | ||
| JNK1alpha1 interacts with c-Jun. | BIND | 12167088 | ||
| MAPK8 (JNK1) phosphorylates JUN (c-Jun) | BIND | 16007099 | ||
| JNK1alpha2 interacts with c-Jun. | BIND | 12167088 | ||
| MAPK8 | ELK1 | An unspecified isoform of JNK1 interacts with and phosphorylates Elk1. | BIND | 9235954 |
| Biochemical Activity | BioGRID | 8586671 | ||
| Elk-1 is phosphorylated by JNK-1. This interaction was modeled on a demonstrated interaction between human Elk-1 and JNK-1 from an unspecified species. | BIND | 9020136 | ||
| MAPK8 | GSTP1 | - | HPRD,BioGRID | 11279197 |12646564 |
| MAPK8 | SPIB | - | HPRD,BioGRID | 8632909 |
| MAPK8 | SH2D3A | Phenotypic Enhancement | BioGRID | 10187783 |
| MAPK8 | DUSP1 | - | HPRD,BioGRID | 11278799 |
| MAPK8 | SH3BP5 | Sab interacts with JNK1-alpha-2. | BIND | 12167088 |
| Sab interacts with JNK1-alpha-1. | BIND | 12167088 | ||
| - | HPRD,BioGRID | 12167088 | ||
| Sab interacts with JNK1-beta-2. | BIND | 12167088 | ||
| Sab interacts with JNK1-beta-1. | BIND | 12167088 | ||
| MAPK8 | TNFRSF10B | Co-purification | BioGRID | 15659383 |
| MAPK8 | JUND | - | HPRD,BioGRID | 12052834 |
| MAPK8 | DUSP10 | - | HPRD,BioGRID | 10391943 |10597297 |
| An unspecified isoform of MAPK8 interacts with DUSP10. This interaction was modelled on a demonstrated interaction between MAPK8 from an unspecified species and human DUSP10. | BIND | 10391943 | ||
| MAPK8 | ARHGDIA | Co-purification | BioGRID | 15659383 |
| MAPK8 | ATF2 | Affinity Capture-Western; Biochemical Activity; Reconstituted Complex | BioGRID | 7535770 |9207092 |9405416 |11279118 |
| - | HPRD | 7737129 |7737130 | ||
| MAPK8 | IKBKAP | - | HPRD,BioGRID | 12058026 |
| MAPK8 | BCAR1 | Affinity Capture-Western | BioGRID | 11432831 |
| MAPK8 | SH3BP5 | Sab interacts with JNK1-alpha-2. | BIND | 12167088 |
| Sab interacts with JNK1-alpha-1. | BIND | 12167088 | ||
| - | HPRD,BioGRID | 12167088 | ||
| Sab interacts with JNK1-beta-2. | BIND | 12167088 | ||
| Sab interacts with JNK1-beta-1. | BIND | 12167088 | ||
| MAPK8 | RHOA | Co-purification | BioGRID | 15659383 |
| MAPK8 | TP53 | - | HPRD,BioGRID | 9393873|9732264 |
| AKT1 | PAK1 | Reconstituted Complex | BioGRID | 14749719 |
| AKT1 | MDM2 | HDM2 interacts with and is phosphorylated by Akt. | BIND | 11960368 |
| AKT1 | YWHAZ | - | HPRD,BioGRID | 11956222 |
| Akt interaction with and phosphorylation of 14-3-3 zeta at the same residue as MAPKAPK2. | BIND | 11956222 | ||
| AKT1 | IMPDH2 | The pleckstrin homology domain of PKB/Akt-alpha interacts with IMPDH type II. | BIND | 10930578 |
| - | HPRD,BioGRID | 10930578 | ||
| AKT1 | AR | Akt phosphorylates AR. | BIND | 11404460 |12621049 |
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 11404460 | ||
| AKT1 | NR4A1 | - | HPRD,BioGRID | 11274386 |
| AKT1 | FOXO4 | - | HPRD | 11313479 |
| AKT1 interacts with MLLT7 (FOXO4). This interaction was modelled on a demonstrated interaction between human AKT1 and FOXO4 from an unspecified species. | BIND | 15688030 | ||
| AKT1 | ARHGAP29 | Two-hybrid | BioGRID | 14749388 |
| AKT1 | SMAD3 | Affinity Capture-Western | BioGRID | 16362038 |
| AKT1 | RPS6KB1 | - | HPRD | 11438723 |
| Co-purification | BioGRID | 15149849 | ||
| AKT1 | YWHAZ | - | HPRD,BioGRID | 11956222 |
| Akt interaction with and phosphorylation of 14-3-3 zeta at the same residue as MAPKAPK2. | BIND | 11956222 | ||
| AKT1 | SMAD4 | Affinity Capture-Western | BioGRID | 16362038 |
| AKT1 | PEA15 | Akt interacts with PED. | BIND | 12808093 |
| AKT1 | TSC1 | - | HPRD,BioGRID | 12167664 |
| AKT1 | HSP90AA1 | - | HPRD,BioGRID | 10995457 |
| AKT1 | PDPK1 | - | HPRD,BioGRID | 11825911 |
| PDK1 phosphorylates Akt1. | BIND | 15718470 | ||
| AKT1 | IRAK1 | - | HPRD,BioGRID | 11976320 |
| AKT1 | TRIB3 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 12791994 |
| AKT1 | TCL1B | - | HPRD,BioGRID | 10983986 |
| TCL1B interacts with AKT1. | BIND | 11707444 | ||
| AKT1 | TSC2 | - | HPRD,BioGRID | 12167664 |
| Akt interacts with and phosphorylates tuberin. This interaction was modelled on a demonstrated interaction between Akt from an unspecified species and human Tuberin. | BIND | 12150915 | ||
| AKT1 | RICS | Biochemical Activity | BioGRID | 12446789 |
| AKT1 | PDK1 | PDK1 interacts with and phosphorylates Akt1. This interaction was modeled on a demonstrated interaction between PDK1 and Akt1, both from unspecified species. | BIND | 15678105 |
| AKT1 | BRAF | - | HPRD,BioGRID | 10869359 |
| AKT1 | KTN1 | Two-hybrid | BioGRID | 11162552 |
| AKT1 | CHUK | - | HPRD,BioGRID | 10485710 |
| AKT1 | HSP90AB1 | Affinity Capture-Western | BioGRID | 10995457 |
| AKT1 | PHLPP | PHLPP interacts with Akt. This interaction was modelled on a demonstrated interaction between human PHLPP and Akt from an unspecified species. | BIND | 15808505 |
| AKT1 | ARFIP2 | Two-hybrid | BioGRID | 9312003 |
| AKT1 | CSNK2A1 | CK2 interacts with and phosphorylates Akt. This interaction was modeled on a demonstrated interaction between human CK2 and Akt from an unspecified species and mouse. | BIND | 15818404 |
| AKT1 | PTPN1 | - | HPRD | 11579209 |
| AKT1 | FANCA | Two-hybrid | BioGRID | 14499622 |
| AKT1 | PDPK1 | - | HPRD,BioGRID | 11825911 |
| PDK1 phosphorylates Akt1. | BIND | 15718470 | ||
| AKT1 | YBX1 | Akt-1 interacts with and phosphorylates YB-1. | BIND | 15806160 |
| AKT1 | PAK6 | Reconstituted Complex | BioGRID | 11773441 |
| AKT1 | PKN2 | - | HPRD,BioGRID | 10926925 |
| AKT1 | RICTOR | Reconstituted Complex | BioGRID | 15718470 |
| AKT1 | GSK3B | AKT1 interacts with and phosphorylates GSK3B. This interaction was modelled on a demonstrated interaction between human AKT1 and GSK3B from an unspecified species. | BIND | 15688030 |
| Reconstituted Complex | BioGRID | 16009706 | ||
| AKT1 | SMAD7 | Affinity Capture-Western | BioGRID | 16362038 |
| AKT1 | MAPKAPK2 | - | HPRD,BioGRID | 11042204 |
| AKT1 | TCL1A | - | HPRD | 10983986 |12009899 |
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 10983986 |11707444 |12009899 | ||
| TCL1 interacts with AKT1. | BIND | 11707444 | ||
| AKT1 | RPS6KB1 | - | HPRD | 11438723 |
| Co-purification | BioGRID | 15149849 | ||
| AKT1 | KRT10 | - | HPRD,BioGRID | 11585925 |
| AKT1 | PLXNA1 | - | HPRD,BioGRID | 15187088 |
| AKT1 | TERT | Affinity Capture-Western | BioGRID | 15843522 |
| AKT1 | PRKCQ | - | HPRD,BioGRID | 11410591 |
| AKT1 | CDKN1B | Affinity Capture-Western; Biochemical Activity | BioGRID | 12042314 |
| AKT1 | CHN2 | Reconstituted Complex | BioGRID | 11278894 |
| AKT1 | AR | Akt phosphorylates AR. | BIND | 11404460 |12621049 |
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 11404460 | ||
| AKT1 | AKTIP | - | HPRD,BioGRID | 14749367 |
| AKT1 | IRS1 | - | HPRD,BioGRID | 10497255 |
| AKT1 | MTCP1 | - | HPRD,BioGRID | 11707444 |
| AKT1 | THEM4 | - | HPRD,BioGRID | 11598301 |
| AKT1 | HSPB1 | Affinity Capture-Western | BioGRID | 11042204 |
| AKT1 | MAPK8IP1 | - | HPRD,BioGRID | 12194869 |
| AKT1 | IMPDH2 | The pleckstrin homology domain of PKB/Akt-alpha interacts with IMPDH type II. | BIND | 10930578 |
| - | HPRD,BioGRID | 10930578 | ||
| AKT1 | RAF1 | - | HPRD,BioGRID | 10576742 |
| AKT1 | BRCA1 | Reconstituted Complex | BioGRID | 10542266 |
| AKT1 | APPL1 | APPL interacts with Akt1. | BIND | 10490823 |
| AKT1 | BAD | Reconstituted Complex | BioGRID | 11500364 |
| AKT1 | TCL1A | - | HPRD | 10983986 |12009899 |
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 10983986 |11707444 |12009899 | ||
| TCL1 interacts with AKT1. | BIND | 11707444 | ||
| AKT1 | TCL1B | - | HPRD,BioGRID | 10983986 |
| TCL1B interacts with AKT1. | BIND | 11707444 | ||
| AKT1 | METTL1 | Mettl1 interacts with and is phosphorylated by PKB-alpha (Akt) | BIND | 15861136 |
| AKT1 | UXS1 | - | HPRD | 11877387 |
| AKT1 | TNFSF11 | - | HPRD | 10635328 |
| AKT1 | TCL1A | - | HPRD | 10983986 |12009899 |
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 10983986 |11707444 |12009899 | ||
| TCL1 interacts with AKT1. | BIND | 11707444 | ||
| AKT1 | PRKCZ | - | HPRD,BioGRID | 10085094 |
| AKT1 | CARHSP1 | Reconstituted Complex | BioGRID | 15910284 |
| AKT1 | PRKDC | DNA-PKcs interacts with Akt1. | BIND | 15678105 |
| AKT1 | FOXO4 | - | HPRD | 11313479 |
| AKT1 interacts with MLLT7 (FOXO4). This interaction was modelled on a demonstrated interaction between human AKT1 and FOXO4 from an unspecified species. | BIND | 15688030 | ||
| AKT1 | HTT | Huntingtin is serine-phosphorylated by Akt. | BIND | 12062094 |
| AKT1 | GAB2 | - | HPRD,BioGRID | 11782427 |
| AKT1 | SMAD2 | Affinity Capture-Western | BioGRID | 16362038 |
| AKT1 | NCF1C | Akt interaction with and phosphorylation of p47-phox | BIND | 12734380 |
| AKT1 | GSK3B | AKT1 interacts with and phosphorylates GSK3B. This interaction was modelled on a demonstrated interaction between human AKT1 and GSK3B from an unspecified species. | BIND | 15688030 |
| Reconstituted Complex | BioGRID | 16009706 | ||
| AKT1 | TSC2 | - | HPRD,BioGRID | 12167664 |
| Akt interacts with and phosphorylates tuberin. This interaction was modelled on a demonstrated interaction between Akt from an unspecified species and human Tuberin. | BIND | 12150915 | ||
| AKT1 | ILK | - | HPRD,BioGRID | 9736715 |
| AKT1 | GRB10 | - | HPRD | 11809791 |
| AKT1 | PIAS2 | Miz1 interacts with Akt. | BIND | 15580267 |
| AKT1 | FRAP1 | Protein-peptide; Reconstituted Complex | BioGRID | 10910062 |14970221 |15718470 |
| AKT1 | MAPKAP1 | Affinity Capture-Western | BioGRID | 16962653 |
| MAP3K11 | IKBKB | - | HPRD,BioGRID | 10713178 |
| MAP3K11 | KIF3B | Two-hybrid | BioGRID | 9427749 |
| MAP3K11 | KIFAP3 | Two-hybrid | BioGRID | 9427749 |
| MAP3K11 | MAPK8IP2 | - | HPRD,BioGRID | 10490659 |
| MAP3K11 | CHUK | - | HPRD,BioGRID | 10713178 |
| MAP3K11 | MAP2K1 | MEK1 interacts with MLK3. | BIND | 15258589 |
| MAP3K11 | KIF3A | - | HPRD,BioGRID | 9427749 |
| MAP3K11 | RAC1 | - | HPRD | 9427749 |
| MAP3K11 | MAPK8IP1 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 10490659 |
| MAP3K11 | DLG4 | Affinity Capture-Western | BioGRID | 11152698 |
| MAP3K11 | CDC42 | - | HPRD,BioGRID | 10799501 |
| MAP3K11 | SH3RF1 | - | HPRD,BioGRID | 14504284 |
| MAP3K11 | RHOG | - | HPRD,BioGRID | 12376551 |
| MAP3K11 | MAP4K1 | - | HPRD,BioGRID | 11053428 |
| MAP3K11 | KIF17 | Two-hybrid | BioGRID | 9427749 |
| MAPK8IP3 | SRC | Biochemical Activity | BioGRID | 12226752 |
| MAPK8IP3 | PTK2 | Affinity Capture-Western | BioGRID | 12226752 |
| MAPK8IP3 | MAP2K1 | - | HPRD,BioGRID | 10523642 |11044439 |
| MAPK8IP3 | MAP3K5 | - | HPRD,BioGRID | 12189133 |
| MAPK8IP3 | RAF1 | - | HPRD,BioGRID | 10523642 |11044439 |
| - | HPRD | 11044439 | ||
| MAPK8IP3 | MAPK9 | - | HPRD,BioGRID | 10523642 |10629060 |12189133 |
| MAPK8IP3 | MAPK8IP1 | - | HPRD,BioGRID | 10629060 |
| MAPK8IP3 | RAF1 | - | HPRD,BioGRID | 10523642 |11044439 |
| - | HPRD | 11044439 | ||
| MAPK8IP3 | MAPK8IP2 | - | HPRD,BioGRID | 10629060 |
| MAPK8IP3 | KLC1 | - | HPRD,BioGRID | 11106729 |
| MAPK8IP3 | RIC8A | Two-hybrid | BioGRID | 16169070 |
| MAPK8IP3 | MAPK10 | - | HPRD,BioGRID | 10523642 |10629060 |12189133 |
| MAPK8IP3 | KLC2 | - | HPRD,BioGRID | 11106729 |
| MAPK8IP3 | ARL4D | Two-hybrid | BioGRID | 16169070 |
| DUSP22 | MAPK1 | Affinity Capture-Western; Biochemical Activity | BioGRID | 11346645 |
| ZAK | TGFBR1 | - | HPRD,BioGRID | 15465036 |
| ZAK | SFN | Affinity Capture-MS | BioGRID | 15778465 |
| ZAK | ZNF33A | ZAK interacts with ZNF33A (ZZaPK). | BIND | 12535642 |
| - | HPRD,BioGRID | 12535642 | ||
| ZAK | ZNF567 | Two-hybrid | BioGRID | 16189514 |
| ZAK | MAP2K6 | - | HPRD | 11836244 |
| ZAK | ZNF33A | ZAK interacts with ZNF33A (ZZaPK). | BIND | 12535642 |
| - | HPRD,BioGRID | 12535642 | ||
| MAP4K2 | TRAF2 | - | HPRD,BioGRID | 9712898 |
| The carboxy-terminal TRAF domain of TRAF2 interacts with the carboxy-terminal domain of GCK. | BIND | 9712898 | ||
| MAP4K2 | TRAF2 | - | HPRD,BioGRID | 9712898 |
| The carboxy-terminal TRAF domain of TRAF2 interacts with the carboxy-terminal domain of GCK. | BIND | 9712898 | ||
| MAP4K2 | RAB8A | - | HPRD,BioGRID | 8643544 |
| FLNC | PHLDB2 | - | HPRD,BioGRID | 12376540 |
| FLNC | MYOZ3 | - | HPRD,BioGRID | 11842093 |
| Calsarcin-3 interacts with gamma-filamin. | BIND | 11842093 | ||
| FLNC | MYOZ1 | FATZ interacts with FLNC. | BIND | 10984498 |
| - | HPRD,BioGRID | 10984498 |11171996 | ||
| Calsarcin-2 interacts with gamma-filamin. | BIND | 11842093 | ||
| FLNC | MYOZ3 | - | HPRD,BioGRID | 11842093 |
| Calsarcin-3 interacts with gamma-filamin. | BIND | 11842093 | ||
| FLNC | FURIN | - | HPRD | 9412467 |
| FLNC | KCND2 | Reconstituted Complex; Two-hybrid | BioGRID | 11102480 |
| FLNC | NPHP1 | - | HPRD | 12006559 |
| FLNC | MYOZ1 | FATZ interacts with FLNC. | BIND | 10984498 |
| - | HPRD,BioGRID | 10984498 |11171996 | ||
| Calsarcin-2 interacts with gamma-filamin. | BIND | 11842093 | ||
| FLNC | MYOZ1 | FATZ interacts with FLNC. | BIND | 10984498 |
| - | HPRD,BioGRID | 10984498 |11171996 | ||
| Calsarcin-2 interacts with gamma-filamin. | BIND | 11842093 | ||
| FLNC | MYOT | - | HPRD,BioGRID | 11038172 |
| FLNC | SGCD | - | HPRD,BioGRID | 10629222 |14506720 |
| FLNC | KY | KY interacts with FLNC. This interaction was modeled on a demonstrated interaction between mouse KY and human FLNC. | BIND | 15385448 |
| FLNC | SGCG | - | HPRD,BioGRID | 10629222 |
| FLNC | CAPN3 | - | HPRD,BioGRID | 14506720 |
| FLNC | MYOZ2 | Calsarcin-1 interacts with gamma-filamin. | BIND | 11842093 |
| Affinity Capture-Western | BioGRID | 11842093 | ||
| FLNC | MYOZ2 | Calsarcin-1 interacts with gamma-filamin. | BIND | 11842093 |
| Affinity Capture-Western | BioGRID | 11842093 | ||
| FLNC | INPPL1 | - | HPRD,BioGRID | 11739414 |
| MAP3K12 | MAPK8IP2 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 10490659 |
| MAP3K12 | SH3RF1 | - | HPRD | 14504284 |
| MAP3K12 | MAPK8IP1 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 10490659 |
| MAP3K12 | TSC22D1 | Two-hybrid | BioGRID | 16169070 |
| MAP3K12 | RGS1 | Two-hybrid | BioGRID | 16169070 |
| MAP3K12 | FTL | Two-hybrid | BioGRID | 16169070 |
| MAP3K12 | MBIP | - | HPRD,BioGRID | 10801814 |
| MAP3K2 | PKN2 | - | HPRD,BioGRID | 10818102 |
| MAP3K2 | SH2D2A | Affinity Capture-Western; Two-hybrid | BioGRID | 11073940 |
| MAP3K2 | MAP2K5 | Affinity Capture-Western; Two-hybrid | BioGRID | 11073940 |
| MEKK2 phosphorylates an unspecified isoform of MEK5. This interaction was modeled on a demonstrated interaction between MEKK2 from an unspecified species and MEK5 from an unspecified species. | BIND | 12659851 | ||
| MAP3K2 | MAP3K5 | - | HPRD | 12912994 |
| MAP3K2 | MAP2K5 | Affinity Capture-Western; Two-hybrid | BioGRID | 11073940 |
| MEKK2 phosphorylates an unspecified isoform of MEK5. This interaction was modeled on a demonstrated interaction between MEKK2 from an unspecified species and MEK5 from an unspecified species. | BIND | 12659851 | ||
| MAP3K2 | YWHAG | - | HPRD | 15324660 |
| MAP3K2 | YWHAZ | - | HPRD | 9452471 |
| MAP3K2 | YWHAE | - | HPRD,BioGRID | 9452471 |
| MAP3K2 | SFN | Affinity Capture-MS | BioGRID | 15778465 |
| FLNA | FURIN | - | HPRD | 9412467 |
| FLNA | TRIO | - | HPRD,BioGRID | 11146652 |
| FLNA | FLNB | - | HPRD,BioGRID | 12393796 |
| FLNA | FBLIM1 | - | HPRD,BioGRID | 12679033 |
| FLNA | CMIP | - | HPRD,BioGRID | 15128042 |
| FLNA | DRD3 | Dopamine receptor D3 interacts with filamin A. This interaction was modeled on a demonstrated interaction between human FLN-A and D3 from unspecified source. | BIND | 11320256 |
| - | HPRD,BioGRID | 11911837 | ||
| FLNA | GRIK3 | - | HPRD | 11943148 |
| FLNA | CAV1 | - | HPRD | 10637311 |
| FLNA | BRCA2 | - | HPRD,BioGRID | 11602572 |
| BRCA2 interacts with hsFLNa. | BIND | 11602572 | ||
| FLNA | DRD3 | Dopamine receptor D3 interacts with filamin A. This interaction was modeled on a demonstrated interaction between human FLN-A and D3 from unspecified source. | BIND | 11320256 |
| - | HPRD,BioGRID | 11911837 | ||
| FLNA | DRD2 | Affinity Capture-Western | BioGRID | 12181426 |
| Dopamine receptor D2 interacts with filamin A. This interaction was modeled on a demonstrated interaction between human FLN-A and D2 from unspecified source. | BIND | 11320256 | ||
| - | HPRD | 11911837 | ||
| FLNA | ITGB1 | - | HPRD,BioGRID | 9722563 |11807098 |
| FLNA | VHL | The von Hippel-Lindau tumor suppressor protein (pVHL) interacts with FLNA . | BIND | 12169691 |
| - | HPRD,BioGRID | 8674032 |12169691 | ||
| FLNA | TNIP2 | - | HPRD | 12753905 |
| FLNA | RALA | - | HPRD,BioGRID | 10051605 |
| FLNA | NPHP1 | - | HPRD,BioGRID | 12006559 |
| FLNA | SH2B3 | - | HPRD,BioGRID | 11163396 |
| FLNA | RHOA | - | HPRD | 10051605 |
| FLNA | RAC1 | - | HPRD | 10051605 |
| FLNA | VHL | The von Hippel-Lindau tumor suppressor protein (pVHL) interacts with FLNA . | BIND | 12169691 |
| - | HPRD,BioGRID | 8674032 |12169691 | ||
| FLNA | BRCA1 | - | HPRD | 11602572 |
| FLNA | BRCA2 | - | HPRD,BioGRID | 11602572 |
| BRCA2 interacts with hsFLNa. | BIND | 11602572 | ||
| FLNA | F3 | - | HPRD,BioGRID | 9490735 |
| FLNA | MAP3K7IP2 | - | HPRD | 14743216 |
| FLNA | GRIK1 | - | HPRD | 11943148 |
| FLNA | TRAF2 | - | HPRD,BioGRID | 10617615 |
| FLNA | SIGLEC10 | - | HPRD,BioGRID | 12055638 |
| FLNA | ITGB7 | - | HPRD,BioGRID | 11781567 |
| FLNA | DRD2 | Affinity Capture-Western | BioGRID | 12181426 |
| Dopamine receptor D2 interacts with filamin A. This interaction was modeled on a demonstrated interaction between human FLN-A and D2 from unspecified source. | BIND | 11320256 | ||
| - | HPRD | 11911837 | ||
| FLNA | GP1BA | - | HPRD,BioGRID | 11700320 |
| FLNA | CASR | - | HPRD,BioGRID | 11390379 |11390380 |
| FLNA | SELE | - | HPRD | 8609175 |
| FLNA | DCN | - | HPRD,BioGRID | 12106908 |
| FLNA | ITGB3 | Two-hybrid | BioGRID | 11807098 |
| FLNA | MYOT | - | HPRD,BioGRID | 11038172 |
| FLNA | DRD2 | Affinity Capture-Western | BioGRID | 12181426 |
| Dopamine receptor D2 interacts with filamin A. This interaction was modeled on a demonstrated interaction between human FLN-A and D2 from unspecified source. | BIND | 11320256 | ||
| - | HPRD | 11911837 | ||
| FLNA | GRM8 | - | HPRD | 11943148 |
| FLNA | AR | - | HPRD,BioGRID | 12682292 |
| FLNA | CDC42 | - | HPRD | 10051605 |
| FLNA | ITGB6 | Two-hybrid | BioGRID | 11807098 |
| SPAG9 | MAP3K3 | - | HPRD,BioGRID | 12391307 |
| SPAG9 | EIF4A2 | Affinity Capture-MS | BioGRID | 17353931 |
| SPAG9 | NFKB1 | - | HPRD,BioGRID | 14743216 |
| NFKB1 (NF-kB1/p105) interacts with an unspecified isoform of SPAG9 (JLP). | BIND | 14743216 | ||
| SPAG9 | MYC | - | HPRD | 12391307 |
| SPAG9 | NFKB1 | - | HPRD,BioGRID | 14743216 |
| NFKB1 (NF-kB1/p105) interacts with an unspecified isoform of SPAG9 (JLP). | BIND | 14743216 | ||
| SPAG9 | MAX | - | HPRD,BioGRID | 12391307 |
| ARRB2 | PES1 | Affinity Capture-MS | BioGRID | 17353931 |
| ARRB2 | AP1B1 | - | HPRD | 10097102 |12070169 |
| ARRB2 | MAPK10 | - | HPRD,BioGRID | 11090355 |11356842 |
| - | HPRD | 11090355 | ||
| ARRB2 | MRPL44 | Affinity Capture-MS | BioGRID | 17353931 |
| ARRB2 | SMO | Beta-arr2 interacts with Smo. This interaction was modeled on a demonstrated interaction between Beta-arr2 and Smo both from an unspecified species. | BIND | 15618519 |
| ARRB2 | NFKBIA | The amino terminus of Beta-Arr2 interacts with the carboxy terminus of I-kappa-B-alpha to prevent I-kappa-B-alpha phosphorylation and degradation. | BIND | 15125834 |
| ARRB2 | MAPK10 | - | HPRD,BioGRID | 11090355 |11356842 |
| - | HPRD | 11090355 | ||
| ARRB2 | PTAFR | - | HPRD,BioGRID | 11729201 |
| - | HPRD | 9037196 | ||
| ARRB2 | RALGDS | - | HPRD,BioGRID | 12105416 |
| ARRB2 | SLC9A5 | Beta-Arr2 interacts with NHE5. | BIND | 15699339 |
| ARRB2 | MRPL43 | Affinity Capture-MS | BioGRID | 17353931 |
| ARRB2 | TCOF1 | Affinity Capture-MS | BioGRID | 17353931 |
| ARRB2 | FBL | Affinity Capture-MS | BioGRID | 17353931 |
| ARRB2 | NTSR1 | - | HPRD | 11279203 |
| ARRB2 | ARF6 | - | HPRD,BioGRID | 11533043 |11867621 |
| ARRB2 | RAB5C | Affinity Capture-MS | BioGRID | 17353931 |
| ARRB2 | KPNA4 | Affinity Capture-MS | BioGRID | 17353931 |
| ARRB2 | LHCGR | Reconstituted Complex | BioGRID | 11867621 |
| ARRB2 | KPNA3 | Affinity Capture-MS | BioGRID | 17353931 |
| ARRB2 | ARRB1 | Affinity Capture-MS | BioGRID | 17353931 |
| ARRB2 | NTS | - | HPRD | 12473660 |
| ARRB2 | MAPK3 | Affinity Capture-Western | BioGRID | 12473660 |
| ARRB2 | MAP3K5 | Affinity Capture-Western | BioGRID | 11090355 |
| - | HPRD | 11356842 | ||
| ARRB2 | AP2B1 | Reconstituted Complex; Two-hybrid | BioGRID | 10097102 |12070169 |
| ARRB2 | MDM2 | - | HPRD,BioGRID | 12488444 |12538596 |
| - | HPRD | 11588219 |12488444 |12538596|12488444 |12538596 | ||
| ARRB2 | STC2 | Two-hybrid | BioGRID | 16169070 |
| ARRB2 | RPL7L1 | Affinity Capture-MS | BioGRID | 17353931 |
| ARRB2 | PDE4D | PDE4D5 interacts with Beta-Arrestin 2. | BIND | 14500724 |
| ARRB2 | AGTR1 | - | HPRD | 11279203 |
| ARRB2 | OXTR | - | HPRD | 11279203 |
| ARRB2 | NOLC1 | Affinity Capture-MS | BioGRID | 17353931 |
| ARRB2 | CLTC | - | HPRD | 10097102 |
| ARRB2 | MAP3K5 | Affinity Capture-Western | BioGRID | 11090355 |
| - | HPRD | 11356842 | ||
| ARRB2 | MDM2 | - | HPRD,BioGRID | 12488444 |12538596 |
| - | HPRD | 11588219 |12488444 |12538596|12488444 |12538596 | ||
| ARRB2 | DDX27 | Affinity Capture-MS | BioGRID | 17353931 |
| ARRB2 | TRH | - | HPRD | 12473660 |
| ARRB2 | CYTH2 | - | HPRD,BioGRID | 11533043 |
| ARRB2 | MED8 | Two-hybrid | BioGRID | 16169070 |
| ARRB2 | SMARCC2 | Two-hybrid | BioGRID | 16169070 |
| ARRB2 | PTAFR | - | HPRD,BioGRID | 11729201 |
| - | HPRD | 9037196 | ||
| ARRB2 | BOP1 | Affinity Capture-MS | BioGRID | 17353931 |
| ARRB2 | AP3B1 | Affinity Capture-MS | BioGRID | 17353931 |
| ARRB2 | OPRD1 | - | HPRD,BioGRID | 11259507 |
| ARRB2 | AVPR2 | - | HPRD,BioGRID | 12473660 |
| MAP2K7 | MAP3K5 | Affinity Capture-Western | BioGRID | 11959862 |
| MAP2K7 | MAPK8IP2 | - | HPRD,BioGRID | 10756100 |
| MAP2K7 | MAPK8IP1 | - | HPRD,BioGRID | 10490659 |
| MAP2K7 | GADD45B | Affinity Capture-Western; Reconstituted Complex | BioGRID | 14743220 |
| MAP2K7 | DUSP19 | - | HPRD,BioGRID | 11959861 |11959862 |
| MAP2K7 | MAP3K13 | Biochemical Activity | BioGRID | 11726277 |
| MAP2K7 | CNKSR1 | CNKSR1 (hCNK1) interacts with MAP2K7 (MKK7). This interaction was modelled on a demonstrated interaction between human CNKSR1 and MAP2K7 from an unspecified species. | BIND | 15753034 |
| MAP3K10 | TUBB2A | - | HPRD | 9629920 |
| MAP3K10 | HTT | MLK2 SH3 domain interacts with Huntingtin | BIND | 10801775 |
| - | HPRD,BioGRID | 10801775 | ||
| MAP3K10 | RACGAP1 | - | HPRD | 9427749 |
| MAP3K10 | KIFAP3 | - | HPRD,BioGRID | 9427749 |
| MAP3K10 | KIF3A | - | HPRD,BioGRID | 9427749 |
| MAP3K10 | HTT | MLK2 SH3 domain interacts with Huntingtin | BIND | 10801775 |
| - | HPRD,BioGRID | 10801775 | ||
| MAP3K10 | PHB | - | HPRD | 9629920 |
| MAP3K10 | CDC42 | - | HPRD,BioGRID | 9427749 |
| MAP3K10 | MAPK8IP2 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 10490659 |
| MAP3K10 | YWHAE | - | HPRD,BioGRID | 9427749 |
| MAP3K10 | NEUROD1 | Affinity Capture-Western; Biochemical Activity; Two-hybrid | BioGRID | 12881483 |
| MAP3K10 | SH3RF1 | - | HPRD | 14504284 |
| MAP3K10 | DNM1 | Reconstituted Complex | BioGRID | 9742220 |
| MAP3K10 | MAPK8IP1 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 10490659 |
| MAP3K10 | KIF3B | - | HPRD | 9427749 |
| MAP3K10 | RAC1 | Reconstituted Complex | BioGRID | 9427749 |
| MAP3K10 | CLTC | - | HPRD,BioGRID | 12105200 |
| MAP3K10 | DLG4 | - | HPRD,BioGRID | 11152698 |
| MAP3K10 | DNM1L | - | HPRD | 9742220 |
| MAP3K10 | CNKSR1 | CNKSR1 (hCNK1) interacts with MAP3K10 (MLK2). This interaction was modelled on a demonstrated interaction between human CNKSR1 and MAP3K10 from an unspecified species. | BIND | 15753034 |
| MAP3K10 | KIF17 | Two-hybrid | BioGRID | 9427749 |
| MAP3K10 | KRTAP3P1 | Affinity Capture-Western | BioGRID | 9427749 |
| MAP3K10 | HPCA | Affinity Capture-Western | BioGRID | 9427749 |
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