Protein-protein interaction for TEK

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Protein-protein interaction data for gene TEK

Degree = 1
Interactor A Interactor B Experimental method Source Pubmed
TEKPTPN11-HPRD10521483 
TEKANGPTL1Tie2 interacts with Ang3. This interaction was modeled on a demonstrated interaction between human Tie2 and mouse Ang3.BIND15542434 
-HPRD10051567 
TEKTNIP2-HPRD12609966 
TEKLCK-HPRD7545683 
TEKGRB2-HPRD7478529 |10521483 
TEKTIE1-HPRD,BioGRID10995770 
TEKANGPT2The receptor binding domain (RBD) of Ang2 interacts with the Tie2 ligand binding domain (LBD). This interaction was modelled on a demonstrated interaction between human Ang2 and Tie2 from an unspecified species.BIND15893672 
Tie2 interacts with Ang2.BIND15542434 
-HPRD,BioGRID9723709 
TEKGRB7-HPRD10521483 
TEKANGPT1-HPRD8980223 |8980224 
|9723709 |12427764 
Tie2 interacts with Ang1.BIND15542434 
Affinity Capture-Western; Reconstituted ComplexBioGRID8980223 |9723709 
|12427764 
TEKANGPT4Tie2 interacts with Ang4.BIND15542434 
-HPRD,BioGRID10051567 
TEKDOK2-HPRD,BioGRID9764820 
TEKPIK3R1-HPRD10521483 
TEKSOCS1Socs1 interacts with TEK. This interaction was modeled on a demonstrated interaction between mouse Socs1 and Tek from an unspecified species.BIND10022833 
-HPRD10022833 
TEKGRB14-HPRD10521483 

Degree = 2
Interactor A Interactor B Experimental method Source Pubmed
PTPN11ERBB4Affinity Capture-MSBioGRID16729043 
PTPN11PILRA-HPRD10660620 
Affinity Capture-WesternBioGRID10903717 
PTPN11GAB1SHP2 interacts with and dephosphorylates Gab1.BIND12582165 
-HPRD,BioGRID11940581 
PTPN11INSR-HPRD,BioGRID7493946 |8135823 
PTPN11GAB2-HPRD10068651 |11287610 
Affinity Capture-Western; Two-hybridBioGRID10391903 |11334882 
|11782427 |12135708 
PTPN11LAIR1-HPRD,BioGRID9285412 
PTPN11PECAM1Affinity Capture-Western; Far Western; Reconstituted ComplexBioGRID9054388 |9774457 
|10350061 |10801826 
PTPN11SIGLEC12-HPRD11328818 
PTPN11TNFRSF1A-HPRD11786908 
PTPN11SOS1Affinity Capture-WesternBioGRID9344843 |9632781 
PTPN11CATCat interacts with Shp-2.BIND15556604 
PTPN11JAK1-HPRD,BioGRID8995399 |11036942 
|12403768 
PTPN11INPP5DAffinity Capture-WesternBioGRID9110989 
PTPN11SLAMF6-HPRD,BioGRID11489943 
PTPN11IGF1R-HPRD,BioGRID7642582 
PTPN11CAV1-HPRD,BioGRID12176037 
caveolin-1 interacts with SH-PTP2.BIND12176037 
PTPN11EPOR-HPRD,BioGRID8639815 
PTPN11BTLA-HPRD,BioGRID12796776 
PTPN11CD84Affinity Capture-WesternBioGRID11689425 
PTPN11PLCG2Affinity Capture-WesternBioGRID12135708 
PTPN11JAK2Biochemical Activity; in vivo; Reconstituted ComplexBioGRID8639815 |8912646 
|8995399 
-HPRD7559603 |8912646 
|8995399 
PTPN11GAB2-HPRD10068651 |11287610 
Affinity Capture-Western; Two-hybridBioGRID10391903 |11334882 
|11782427 |12135708 
PTPN11STAT3-HPRD,BioGRID11594781 
PTPN11PXN-HPRD8986614 |10082579 
|10655584 
PTPN11IRS4-HPRD12774026 
PTPN11MET-HPRD8662733 
PTPN11CD33-HPRD,BioGRID10206955 
PTPN11SYNCRIPTwo-hybridBioGRID9847309 
PTPN11FRS2-HPRD9632781 |11447289 
-HPRD,BioGRID9632781 
PTPN11PTK2-HPRD,BioGRID7589239 |8986614 
|10082579 |10655584 
PTPN11PDGFRBReconstituted Complex; Two-hybridBioGRID7691811 |11266449 
PDGFR interacts with Syp.BIND7688466 
Autophosphorylated PDGFR interacts with Syp. This interaction was modelled on a demonstrated interaction between human PDGFR and Syp from an unspecified species.BIND8890167 
PTPN11TREML1-HPRD,BioGRID15128762 
PTPN11KIT-HPRD,BioGRID7523381 |9528781 
Syp interacts with c-Kit via its SH2 domain.BIND7523381 
PTPN11LY9Affinity Capture-WesternBioGRID11689425 
PTPN11SELE-HPRD,BioGRID11602579 
PTPN11STAT5A-HPRD,BioGRID12060651 
PTPN11JAK2Biochemical Activity; in vivo; Reconstituted ComplexBioGRID8639815 |8912646 
|8995399 
-HPRD7559603 |8912646 
|8995399 
PTPN11MPZL1-HPRD,BioGRID9792637 
PTPN11PDGFRBReconstituted Complex; Two-hybridBioGRID7691811 |11266449 
PDGFR interacts with Syp.BIND7688466 
Autophosphorylated PDGFR interacts with Syp. This interaction was modelled on a demonstrated interaction between human PDGFR and Syp from an unspecified species.BIND8890167 
PTPN11IRS2-HPRD,BioGRID8910607 
PTPN11LIFR-HPRD,BioGRID10800945 
PTPN11PDGFRBReconstituted Complex; Two-hybridBioGRID7691811 |11266449 
PDGFR interacts with Syp.BIND7688466 
Autophosphorylated PDGFR interacts with Syp. This interaction was modelled on a demonstrated interaction between human PDGFR and Syp from an unspecified species.BIND8890167 
PTPN11SLAMF1-HPRD,BioGRID11806999 
CD150 interacts with SHP-2. This interaction was modelled on a demonstrated interaction between human CD150 and monkey SHP-2.BIND11477068 
PTPN11ERBB2Affinity Capture-MSBioGRID16729043 
PTPN11IL4R-HPRD,BioGRID11714803 
PTPN11SIT1-HPRD,BioGRID10209036 |11433379 
|11491537 
PTPN11IL6ST-HPRD,BioGRID10946280 
-HPRD9195977 
PTPN11GAB1SHP2 interacts with and dephosphorylates Gab1.BIND12582165 
-HPRD,BioGRID11940581 
PTPN11FYN-HPRD,BioGRID10212213 
PTPN11SOCS3Affinity Capture-Western; Reconstituted ComplexBioGRID12403768 
PTPN11ROS1Two-hybridBioGRID11266449 
PTPN11PRLRAffinity Capture-WesternBioGRID10991949 
PTPN11FRS2-HPRD9632781 |11447289 
-HPRD,BioGRID9632781 
PTPN11KLRC1-HPRD9485206 
PTPN11PILRA-HPRD10660620 
Affinity Capture-WesternBioGRID10903717 
PTPN11CAV1-HPRD,BioGRID12176037 
caveolin-1 interacts with SH-PTP2.BIND12176037 
PTPN11EPHA2Affinity Capture-WesternBioGRID10655584 
PTPN11SIGLEC11-HPRD,BioGRID11986327 
PTPN11SHC1-HPRD10650943 
PTPN11C6orf25-HPRD,BioGRID11544253 
PTPN11CRKL-HPRD,BioGRID9344843 
PTPN11LEPR-HPRD11018044 
PTPN11BDKRB2-HPRD12177051 
PTPN11PTK2B-HPRD,BioGRID10880513 
PTPN11STAT5BBiochemical Activity; Reconstituted ComplexBioGRID10617656 
PTPN11CEACAM1-HPRD,BioGRID9867848 |12108545 
PTPN11GAB3-HPRD,BioGRID11739737 
PTPN11CSF2RB-HPRD,BioGRID9162089 
PTPN11FLT1Flt-1 interacts with the amino terminal SH2 domain of SHP-2.BIND9600074 
PTPN11BCRPhosphorylated p210bcr-abl interacts with phosphorylated Syp. This interaction was modeled on a demonstrated interaction between human p210bcr-abl and mouse Syp.BIND8195176 
-HPRD12115002 
PTPN11IFNAR1-HPRD9029147 
PTPN11IRS1-HPRD,BioGRID8505282 |9756938 
PTPN11PAG1-HPRD10790433 
PTPN11CTLA4-HPRD,BioGRID8638161 
PTPN11NEDD9-HPRD8879209 
PTPN11FRS3-HPRD11432792 
PTPN11LILRB4-HPRD9422771 
Protein-peptideBioGRID9973385 
PTPN11EGFR-HPRD,BioGRID7673163 
PTPN11BCRPhosphorylated p210bcr-abl interacts with phosphorylated Syp. This interaction was modeled on a demonstrated interaction between human p210bcr-abl and mouse Syp.BIND8195176 
-HPRD12115002 
PTPN11GHR-HPRD,BioGRID10976913 
PTPN11SIGLEC7-HPRD10499918 
PTPN11CSF3R-HPRD,BioGRID9824671 
PTPN11KIT-HPRD,BioGRID7523381 |9528781 
Syp interacts with c-Kit via its SH2 domain.BIND7523381 
PTPN11IL6ST-HPRD,BioGRID10946280 
-HPRD9195977 
PTPN11SLAMF1-HPRD,BioGRID11806999 
CD150 interacts with SHP-2. This interaction was modelled on a demonstrated interaction between human CD150 and monkey SHP-2.BIND11477068 
PTPN11CDH5-HPRD,BioGRID10681592 
PTPN11CTNNB1Affinity Capture-WesternBioGRID10681592 
PTPN11FCRL3Reconstituted ComplexBioGRID12051764 
PTPN11BCAR1Affinity Capture-WesternBioGRID9188452 
PTPN11LILRB4-HPRD9422771 
Protein-peptideBioGRID9973385 
ANGPTL1NR2F6-HPRD10318855 
TNIP2MAP3K8-HPRD,BioGRID14743216 |15169888 
TNIP2SMARCD1-HPRD12753905 
ABIN-2 interacts with BAF60a.BIND12753905 
TNIP2FLNA-HPRD12753905 
TNIP2RELA-HPRD,BioGRID14743216 
TNIP2SMARCD1-HPRD12753905 
ABIN-2 interacts with BAF60a.BIND12753905 
TNIP2TNFAIP3-HPRD10385526 |11389905 
|11390377 
-HPRD10385526 |11390377 
TNIP2NFKB2-HPRD,BioGRID14743216 
TNIP2TNFAIP3-HPRD10385526 |11389905 
|11390377 
-HPRD10385526 |11390377 
TNIP2RELAffinity Capture-MSBioGRID14743216 
TNIP2STK11-HPRD12595760 
TNIP2RELB-HPRD14743216 
TNIP2IKBKG-HPRD14653779 
TNIP2NFKB1-HPRD,BioGRID14743216 |15169888 
LCKPIK3CA-HPRD,BioGRID8020561 
LCKSTAT3-HPRD10825200 
LCKTRPV4-HPRD,BioGRID12538589 
LCKSQSTM1-HPRD,BioGRID8650207 
LCKARHGAP17Reconstituted ComplexBioGRID11431473 
LCKCD38-HPRD10636863 
LCKSH2B3-HPRD,BioGRID10799879 
LCKUNC119-HPRD,BioGRID14757743 
LCKCDC25C-HPRD,BioGRID11389730 
LCKUBE3AReconstituted Complex; Two-hybridBioGRID10449731 
LCKIL2RB-HPRD,BioGRID2047859 
LCKPLCG1-HPRD1500851 
LCKCD5-HPRD7513045 
LCKNOTCH1-HPRD,BioGRID14583609 
LCKDLG1-HPRD,BioGRID9341123 
LCKFCGR3A-HPRD8258691 
LCKCTNND2-HPRD12835311 
LCKPTPN6-HPRD8114715 |11294838 
Biochemical Activity; in vitro; in vivoBioGRID8114715 |10617656 
|11294838 
LCKCTLA4-HPRD,BioGRID9712716 
LCKDNM2An unspecified isoform of Dyn2 interacts with Lck. This interaction was modeled on a demonstrated interaction between human Dyn2 and Lck from an unspecified species.BIND15696170 
LCKADAM15-HPRD,BioGRID11741929 
LCKSYK-HPRD,BioGRID7539035 
LCKPXN-HPRD,BioGRID9488700 
LCKCD44-HPRD,BioGRID8576267 
LCKPRKCQTwo-hybridBioGRID10383400 
LCKTRAT1Reconstituted ComplexBioGRID10790433 
LCKCD48-HPRD,BioGRID12007789 
LCKPTK2B-HPRD,BioGRID9091579 
LCKPI4KAReconstituted ComplexBioGRID8246987 
LCKRAF1-HPRD,BioGRID8939988 
LCKBCAR1-HPRD,BioGRID9020138 
LCKPTPRC-HPRD,BioGRID8473339 |8576115 
LCKZAP70-HPRD,BioGRID10318843 
LCKDOK3-HPRD10733577 
LCKKHDRBS1-HPRD,BioGRID9045636 
Lck interacts with Sam68.BIND11278465 
LCKFAS-HPRD,BioGRID8864141 
LCKCBL-HPRD,BioGRID9178909 |11741956 
|11904433 
LCKCD4-HPRD,BioGRID11854499 
LCKCTNND1Biochemical ActivityBioGRID12835311 
LCKCD3E-HPRD11855827 
LCKCD2-HPRD,BioGRID8551220 
LCKKHDRBS1-HPRD,BioGRID9045636 
Lck interacts with Sam68.BIND11278465 
LCKNFKBIALCK interacts with and phosphorylates NFKBIA (I-kappa-B-alpha). This interaction was modeled on a demonstrated interaction between LCK from an unspecified species and human NFKBIA.BIND14534291 
LCKNR2F2Reconstituted Complex; Two-hybridBioGRID8910285 
LCKCD8BCD8-Beta interacts with Lck.BIND15980863 
LCKAXL-HPRD,BioGRID9178760 
LCKCCR5-HPRD11591716 
LCKKIT-HPRD,BioGRID9788619 
LCKTHY1-HPRD,BioGRID1351058 
LCKPTPN6-HPRD8114715 |11294838 
Biochemical Activity; in vitro; in vivoBioGRID8114715 |10617656 
|11294838 
LCKNEDD9-HPRD,BioGRID8879209 
LCKPECAM1-HPRD,BioGRID9624175 
LCKADAM10Affinity Capture-WesternBioGRID11741929 
LCKCD28-HPRD10430626 
LCKTUB-HPRD10455176 
LCKJAK3-HPRD11278738 
LCKSIT1-HPRD,BioGRID10209036 
LCKPAG1-HPRD,BioGRID10790433 
LCKPLD2-HPRD12697812 
LCKSKAP1-HPRD,BioGRID9195899 
LCKCD55-HPRD1385527 
LCKMS4A1Affinity Capture-WesternBioGRID7545683 
LCKFASLG-HPRD,BioGRID11741599 
GRB2ZAP70Affinity Capture-WesternBioGRID7629168 
GRB2ITGA2B-HPRD,BioGRID8631894 |11964172 
GRB2AXLAxl interacts with an unspecified isoform of Grb2.BIND12470648 
-HPRD,BioGRID9178760 
GRB2PRNP-HPRD11571277 
GRB2SIGLEC7-HPRD8188688 
GRB2PTPN6-HPRD,BioGRID11964172 
GRB2EPHA2-HPRD,BioGRID12400011 
GRB2CLYBLAffinity Capture-MSBioGRID12577067 
GRB2IL2RB-HPRD,BioGRID10602027 
GRB2SNTA1-HPRD,BioGRID11278583 |11551227 
GRB2SPRY2-HPRD,BioGRID10940627 |12402043 
GRB2TUB-HPRD10455176 
GRB2CD22-HPRD,BioGRID11551923 
GRB2HTT-HPRD,BioGRID9079622 
HDP interacts with Grb2.BIND9079622 
GRB2PDGFRAAffinity Capture-WesternBioGRID8943348 
GRB2PTPRAAn unspecified isoform of GRB2 interacts with PTPRA.BIND8670803 
-HPRD,BioGRID7518772 |8670803 
|11923305 
GRB2ITGB4-HPRD9171350 
GRB2CD2AP-HPRD10339567 
GRB2BCL2A1-HPRD9670936 
GRB2NCKIPSD-HPRD11157975 |11509578 
-HPRD,BioGRID11157975 
GRB2SYPAffinity Capture-WesternBioGRID7534299 
GRB2IQGAP1Affinity Capture-MSBioGRID12577067 
GRB2IRS1-HPRD7488107 
Affinity Capture-Western; Reconstituted ComplexBioGRID8491186 |8536716 
|12173038 
GRB2KITKit interacts with Grb2. This interaction was modeled on a demonstrated interaction between mouse proteins.BIND10022833 
Grb2 interacts with c-Kit upon stimulation with SLF. This interaction was modeled on a demonstrated interaction between mouse Grb2 and human c-Kit.BIND7523381 
-HPRD,BioGRID10377264 
GRB2AXLAxl interacts with an unspecified isoform of Grb2.BIND12470648 
-HPRD,BioGRID9178760 
GRB2RHOUWrch-1 interacts with Grb2. This interaction was modeled on a demonstrated interaction between human Wrch-1 and Grb2 from an unspecified species.BIND15556869 
GRB2PTK2Tyrosine-phosphorylated FAK interacts with Grb2.BIND7597091 
-HPRD7997267 
Affinity Capture-Western; Reconstituted ComplexBioGRID8649427 |10085298 
|10806474 |12005431 
|12558988 
Grb2 interacts with FAK. This interaction was modeled on a demonstrated interaction between human Grb2 and mouse FAK.BIND9148935 
GRB2CSF1R-HPRD,BioGRID8262059 |9178909 
|9380408 
GRB2SYN1-HPRD8022809 
-HPRD,BioGRID8022809|10899172 
GRB2DRD3D3 interacts with Grb2.BIND9843378 
-HPRD,BioGRID11384839 
GRB2PIK3R2-HPRD8662998 
GRB2LAT-HPRD9489702 |12359715 
Affinity Capture-Western; Reconstituted ComplexBioGRID9489702 |11368773 
|12186560 
GRB2VAV1-HPRD,BioGRID7809090 
Grb2 interacts with VavBIND9013873 
GRB2PTK2B-HPRD,BioGRID10329689 |10354709 
GRB2BCAR1-HPRD8649368 |8700507 
Affinity Capture-Western; Reconstituted ComplexBioGRID10085298 |10822386 
GRB2MAPK14-HPRD8695800 
GRB2GHR-HPRD,BioGRID9632636 
GRB2KHDRBS1-HPRD7799925 |8576157 
|12112020 
Affinity Capture-Western; Reconstituted ComplexBioGRID9872323 |10467411 
|11960376 
Grb2 interacts with Sam68.BIND9872323 
GRB2DRD4D4.7 interacts with Grb2.BIND9843378 
D4.4 interacts with Grb2.BIND9843378 
-HPRD,BioGRID9843378 
D4.2 interacts with Grb2.BIND9843378 
GRB2VAV3-HPRD,BioGRID11094073 
GRB2TFAP2AAffinity Capture-MSBioGRID12577067 
GRB2ADRB1beta-1-AR interacts with Grb2.BIND9843378 
GRB2ADRB2-HPRD,BioGRID9830057 
GRB2EPPK1Affinity Capture-MSBioGRID12577067 
GRB2EPHB1-HPRD,BioGRID8798570 
GRB2MET-HPRD,BioGRID7511210 |8662889 
|9660480 
GRB2IL6STAffinity Capture-Western; Reconstituted ComplexBioGRID9013873 
GRB2MAP2-HPRD,BioGRID10781592 |11546790|11546790 
GRB2SHC1Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Reconstituted ComplexBioGRID7514169 |7524086 
|7535773 |8112292 
|8195171 |8294403 
|8491186 |8647288 
|8662733 |9045692 
|9083103 |9927207 
|10080542 |10477741 
|10570290 |11302736 
|11505033 |11964172 
|12441060 |12577067 
Shc interacts with Grb2. This interaction was modelled on a demonstrated interaction between Shc from human and Grb2 from rat and an unspecified species.BIND8084588 
-HPRD7524086 |7535773 
|8491186 |11707405 
An unspecified isoform of Grb2 interacts with the p52 isoform of Shc.BIND9148935 
Grb2 interacts with Shc.BIND7515480 |8112292 
|8939605 |10891441 
GRB2RAPSN-HPRD9856458 
GRB2KRT17Affinity Capture-MSBioGRID12577067 
GRB2APP-HPRD12485888 
GRB2ERBB2-HPRD11173924 |11606575|11606575 
-HPRD,BioGRID11606575 
GRB2EGFRGRB2 interacts with an unspecified isoform of EGFR. This interaction was modeled on a demonstrated interaction between human GRB2, and rat EGFR.BIND15782189 
-HPRD1322798 |7527043 
EGFR interacts with GRB2.BIND8305738 
Affinity Capture-MS; Affinity Capture-Western; Reconstituted ComplexBioGRID1322798 |7510700 
|7527043 |8647858 
|9050991 |10026169 
|10085134 |11960376 
|12577067 |16729043 
GRB2NTRK1-HPRD,BioGRID10748052 |11733534 
GRB2SPRY1-HPRD12402043 
GRB2FLT3-HPRD,BioGRID10080542 
GRB2CD28-HPRD,BioGRID7737275 |8576157 
|9694876 
GRB2SOS1Grb2 interacts with Sos1. This interaction was modelled on a demonstrated interaction between rat Grb2 and Sos1.BIND8112292 
-HPRD8479541 |8493579 
Affinity Capture-MS; Affinity Capture-Western; Far Western; Reconstituted Complex; Two-hybridBioGRID7510700 |7514169 
|7629168 |7664271 
|8112292 |8188688 
|8479541 |8695800 
|8810325 |9009162 
|9344843 |9872323 
|10207103 |10319320 
|10477741 |10570290 
|10716926 |11960376 
|11964172 |11997436 
|12577067 
GRB2 interacts with SOS. This interaction was modeled on a demonstrated interaction between human GRB2 and mouse SOS.BIND7862111 
Sos1 interacts with Grb2. This interaction was modeled on a demonstrated interaction between Sos1 and Grb2 from Bos taurus.BIND9374537 
GRB2SIT1-HPRD11433379 
GRB2NEU3-HPRD,BioGRID12730204 
GRB2DAG1-HPRD,BioGRID7744812 
GRB2LAT-HPRD9489702 |12359715 
Affinity Capture-Western; Reconstituted ComplexBioGRID9489702 |11368773 
|12186560 
GRB2MAP4K1-HPRD,BioGRID9346925 |9788432 
|9891069 
HPK1, a Ste-20 homologous serine/threonine kinase interacts with Grb2, an adaptor protein.BIND9891069 
GRB2PTPN22-HPRD,BioGRID11882361 
GRB2KHDRBS1-HPRD7799925 |8576157 
|12112020 
Affinity Capture-Western; Reconstituted ComplexBioGRID9872323 |10467411 
|11960376 
Grb2 interacts with Sam68.BIND9872323 
GRB2ADA-HPRD9299436 
GRB2LCP2Affinity Capture-Western; Reconstituted ComplexBioGRID8695800 |8995445 
|10204582 |10224278 
|11314042 
GRB2CBLGrb2 interacts with Cbl.BIND15782196 
c-Cbl interacts with Grb2. This interaction was modeled on a demonstrated interaction between human c-Cbl and Grb2 from an unspecified species.BIND11053437 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID8083187 |9108392 
|9174058 |9178909 
|9367879 |9461587 
|9872323 |10086340 
|10204582 |10570290 
|11964172 |11997436 
-HPRD9108392 |9178909 
|11133830 |11964172 
GRB2PTPRE-HPRD,BioGRID10490839 
GRB2SRC-HPRD,BioGRID11964172 
GRB2PTK2Tyrosine-phosphorylated FAK interacts with Grb2.BIND7597091 
-HPRD7997267 
Affinity Capture-Western; Reconstituted ComplexBioGRID8649427 |10085298 
|10806474 |12005431 
|12558988 
Grb2 interacts with FAK. This interaction was modeled on a demonstrated interaction between human Grb2 and mouse FAK.BIND9148935 
GRB2PXNReconstituted ComplexBioGRID10085298 
GRB2USP6NLGrb2 interacts with RN-tre.BIND12399475 
-HPRD,BioGRID12399475 
GRB2FLT4-HPRD,BioGRID7675451 |7970715 
|8662748 |9927207 
GRB2DRD4D4.7 interacts with Grb2.BIND9843378 
D4.4 interacts with Grb2.BIND9843378 
-HPRD,BioGRID9843378 
D4.2 interacts with Grb2.BIND9843378 
GRB2HTT-HPRD,BioGRID9079622 
HDP interacts with Grb2.BIND9079622 
GRB2SHKBP1-HPRD,BioGRID11152963 
GRB2ITGA6-HPRD7556090 
GRB2MAP4K1-HPRD,BioGRID9346925 |9788432 
|9891069 
HPK1, a Ste-20 homologous serine/threonine kinase interacts with Grb2, an adaptor protein.BIND9891069 
GRB2CCL5-HPRD9009162 
GRB2HRAS-HPRD11352655 
GRB2ADAM15-HPRD,BioGRID11741929 
GRB2RALGPS1-HPRD,BioGRID10747847 
GRB2PTPN1-HPRD10660596 |12388170 
Reconstituted ComplexBioGRID8940134 |10660596 
GRB2EGFRGRB2 interacts with an unspecified isoform of EGFR. This interaction was modeled on a demonstrated interaction between human GRB2, and rat EGFR.BIND15782189 
-HPRD1322798 |7527043 
EGFR interacts with GRB2.BIND8305738 
Affinity Capture-MS; Affinity Capture-Western; Reconstituted ComplexBioGRID1322798 |7510700 
|7527043 |8647858 
|9050991 |10026169 
|10085134 |11960376 
|12577067 |16729043 
GRB2BCRGrb2 interacts with Bcr-Abl.BIND9872323 
-HPRD,BioGRID8112292 |9178913 
Tyrosine phosphorylated Bcr-Abl interacts with Grb2.BIND8112292 
GRB2SHC1Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Reconstituted ComplexBioGRID7514169 |7524086 
|7535773 |8112292 
|8195171 |8294403 
|8491186 |8647288 
|8662733 |9045692 
|9083103 |9927207 
|10080542 |10477741 
|10570290 |11302736 
|11505033 |11964172 
|12441060 |12577067 
Shc interacts with Grb2. This interaction was modelled on a demonstrated interaction between Shc from human and Grb2 from rat and an unspecified species.BIND8084588 
-HPRD7524086 |7535773 
|8491186 |11707405 
An unspecified isoform of Grb2 interacts with the p52 isoform of Shc.BIND9148935 
Grb2 interacts with Shc.BIND7515480 |8112292 
|8939605 |10891441 
GRB2DOCK1Co-fractionation; Reconstituted ComplexBioGRID8657152 |12615911 
GRB2PSMD10-HPRD9009162 
GRB2MUC1-HPRD,BioGRID7664271 
GRB2PLCG1-HPRD,BioGRID9281317 
GRB2EGFRGRB2 interacts with an unspecified isoform of EGFR. This interaction was modeled on a demonstrated interaction between human GRB2, and rat EGFR.BIND15782189 
-HPRD1322798 |7527043 
EGFR interacts with GRB2.BIND8305738 
Affinity Capture-MS; Affinity Capture-Western; Reconstituted ComplexBioGRID1322798 |7510700 
|7527043 |8647858 
|9050991 |10026169 
|10085134 |11960376 
|12577067 |16729043 
GRB2MST1R-HPRD,BioGRID8918464 
GRB2CD72-HPRD10820378 
GRB2USP8-HPRD,BioGRID10982817 |13129930 
GRB2PDGFRB-HPRD,BioGRID7935391 
GRB2SHC3An unspecified isoform of GRB2 interacts with SHC3 (ShcC).BIND15735675 
GRB2JAK2-HPRD,BioGRID7500025 
GRB2SYN1-HPRD8022809 
-HPRD,BioGRID8022809|10899172 
GRB2EPS15Far WesternBioGRID7797522 
GRB2ANXA2-HPRD,BioGRID7510700 
GRB2PAG1-HPRD,BioGRID10790433 
GRB2VAV2-HPRD,BioGRID11606575 
GRB2RACGAP1Affinity Capture-MSBioGRID12577067 
GRB2TRAT1Reconstituted ComplexBioGRID10790433 
GRB2ADAM12-HPRD11127814 
GRB2MAP3K1Affinity Capture-Western; Reconstituted ComplexBioGRID9733714 
GRB2SOS1Grb2 interacts with Sos1. This interaction was modelled on a demonstrated interaction between rat Grb2 and Sos1.BIND8112292 
-HPRD8479541 |8493579 
Affinity Capture-MS; Affinity Capture-Western; Far Western; Reconstituted Complex; Two-hybridBioGRID7510700 |7514169 
|7629168 |7664271 
|8112292 |8188688 
|8479541 |8695800 
|8810325 |9009162 
|9344843 |9872323 
|10207103 |10319320 
|10477741 |10570290 
|10716926 |11960376 
|11964172 |11997436 
|12577067 
GRB2 interacts with SOS. This interaction was modeled on a demonstrated interaction between human GRB2 and mouse SOS.BIND7862111 
Sos1 interacts with Grb2. This interaction was modeled on a demonstrated interaction between Sos1 and Grb2 from Bos taurus.BIND9374537 
GRB2SKAP1-HPRD,BioGRID12171928 
GRB2ADAM10Affinity Capture-WesternBioGRID11741929 
GRB2SH2B2Affinity Capture-WesternBioGRID9856458 
GRB2CSF3R-HPRD,BioGRID9824671 
GRB2FRS2Affinity Capture-Western; Reconstituted ComplexBioGRID8780727 |9182757 
|10092678 |11997436 
-HPRD8780727|9182757|11997436 |12402043 
GRB2SOS1Grb2 interacts with Sos1. This interaction was modelled on a demonstrated interaction between rat Grb2 and Sos1.BIND8112292 
-HPRD8479541 |8493579 
Affinity Capture-MS; Affinity Capture-Western; Far Western; Reconstituted Complex; Two-hybridBioGRID7510700 |7514169 
|7629168 |7664271 
|8112292 |8188688 
|8479541 |8695800 
|8810325 |9009162 
|9344843 |9872323 
|10207103 |10319320 
|10477741 |10570290 
|10716926 |11960376 
|11964172 |11997436 
|12577067 
GRB2 interacts with SOS. This interaction was modeled on a demonstrated interaction between human GRB2 and mouse SOS.BIND7862111 
Sos1 interacts with Grb2. This interaction was modeled on a demonstrated interaction between Sos1 and Grb2 from Bos taurus.BIND9374537 
GRB2IRS4-HPRD,BioGRID9553137 
GRB2SHB-HPRD,BioGRID9484780 |10488157 
GRB2IRS1-HPRD7488107 
Affinity Capture-Western; Reconstituted ComplexBioGRID8491186 |8536716 
|12173038 
GRB2DNM1Affinity Capture-Western; Far Western; Reconstituted ComplexBioGRID8119878 |9009162 
-HPRD8119878 |11877424 
GRB2TFAP2BAffinity Capture-MSBioGRID12577067 
GRB2SOS2-HPRD,BioGRID7629138 |10940929 
GRB2MED28-HPRD,BioGRID15467741 
GRB2PIK3C2B-HPRD,BioGRID11533253 
GRB2BAT2-HPRD,BioGRID14667819 
GRB2PTPRAAn unspecified isoform of GRB2 interacts with PTPRA.BIND8670803 
-HPRD,BioGRID7518772 |8670803 
|11923305 
GRB2FRS2Affinity Capture-Western; Reconstituted ComplexBioGRID8780727 |9182757 
|10092678 |11997436 
-HPRD8780727|9182757|11997436 |12402043 
GRB2WASF1-HPRD9307968 
GRB2PLEC1Affinity Capture-MSBioGRID12577067 
GRB2BCRGrb2 interacts with Bcr-Abl.BIND9872323 
-HPRD,BioGRID8112292 |9178913 
Tyrosine phosphorylated Bcr-Abl interacts with Grb2.BIND8112292 
GRB2KRT18Affinity Capture-MSBioGRID12577067 
GRB2RASA1-HPRD,BioGRID12441060 
GRB2NCKIPSD-HPRD11157975 |11509578 
-HPRD,BioGRID11157975 
GRB2LAX1-HPRD,BioGRID12359715 
GRB2TNK2-HPRD,BioGRID8647288 
GRB2SYNCRIPReconstituted ComplexBioGRID9341187 
GRB2ALOX5-HPRD,BioGRID7929073 |8585605 
GRB2CBLGrb2 interacts with Cbl.BIND15782196 
c-Cbl interacts with Grb2. This interaction was modeled on a demonstrated interaction between human c-Cbl and Grb2 from an unspecified species.BIND11053437 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID8083187 |9108392 
|9174058 |9178909 
|9367879 |9461587 
|9872323 |10086340 
|10204582 |10570290 
|11964172 |11997436 
-HPRD9108392 |9178909 
|11133830 |11964172 
GRB2PTPRC-HPRD8570203 
GRB2CBLB-HPRD,BioGRID10086340 
GRB2PRKAR1A-HPRD,BioGRID9050991 
GRB2ERBB3Affinity Capture-MSBioGRID16729043 
GRB2VAV1-HPRD,BioGRID7809090 
Grb2 interacts with VavBIND9013873 
GRB2SOS1Grb2 interacts with Sos1. This interaction was modelled on a demonstrated interaction between rat Grb2 and Sos1.BIND8112292 
-HPRD8479541 |8493579 
Affinity Capture-MS; Affinity Capture-Western; Far Western; Reconstituted Complex; Two-hybridBioGRID7510700 |7514169 
|7629168 |7664271 
|8112292 |8188688 
|8479541 |8695800 
|8810325 |9009162 
|9344843 |9872323 
|10207103 |10319320 
|10477741 |10570290 
|10716926 |11960376 
|11964172 |11997436 
|12577067 
GRB2 interacts with SOS. This interaction was modeled on a demonstrated interaction between human GRB2 and mouse SOS.BIND7862111 
Sos1 interacts with Grb2. This interaction was modeled on a demonstrated interaction between Sos1 and Grb2 from Bos taurus.BIND9374537 
GRB2JAK1-HPRD,BioGRID8536716 |11527382 
GRB2CRKAffinity Capture-Western; Far Western; Reconstituted ComplexBioGRID8662907 |8810325 
|10970810 
-HPRD8662907 |10970810 
GRB2TP63-HPRD8695800 
GRB2KHDRBS2-HPRD10077576 
GRB2PAK1PAK1 interacts with Grb2.BIND12522133 
GRB2KHDRBS1-HPRD7799925 |8576157 
|12112020 
Affinity Capture-Western; Reconstituted ComplexBioGRID9872323 |10467411 
|11960376 
Grb2 interacts with Sam68.BIND9872323 
GRB2SHC1Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Reconstituted ComplexBioGRID7514169 |7524086 
|7535773 |8112292 
|8195171 |8294403 
|8491186 |8647288 
|8662733 |9045692 
|9083103 |9927207 
|10080542 |10477741 
|10570290 |11302736 
|11505033 |11964172 
|12441060 |12577067 
Shc interacts with Grb2. This interaction was modelled on a demonstrated interaction between Shc from human and Grb2 from rat and an unspecified species.BIND8084588 
-HPRD7524086 |7535773 
|8491186 |11707405 
An unspecified isoform of Grb2 interacts with the p52 isoform of Shc.BIND9148935 
Grb2 interacts with Shc.BIND7515480 |8112292 
|8939605 |10891441 
GRB2REPS2-HPRD,BioGRID9422736 
GRB2ERBB4Affinity Capture-MSBioGRID16729043 
GRB2CALD1-HPRD10559276 
GRB2CBLGrb2 interacts with Cbl.BIND15782196 
c-Cbl interacts with Grb2. This interaction was modeled on a demonstrated interaction between human c-Cbl and Grb2 from an unspecified species.BIND11053437 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID8083187 |9108392 
|9174058 |9178909 
|9367879 |9461587 
|9872323 |10086340 
|10204582 |10570290 
|11964172 |11997436 
-HPRD9108392 |9178909 
|11133830 |11964172 
GRB2GAB2Affinity Capture-Western; Reconstituted ComplexBioGRID10391903 |11782427 
|15143164 
-HPRD10068651 |11882361 
GRB2MAPK9Reconstituted ComplexBioGRID7642542 |9019171 
GRB2SOS1Grb2 interacts with Sos1. This interaction was modelled on a demonstrated interaction between rat Grb2 and Sos1.BIND8112292 
-HPRD8479541 |8493579 
Affinity Capture-MS; Affinity Capture-Western; Far Western; Reconstituted Complex; Two-hybridBioGRID7510700 |7514169 
|7629168 |7664271 
|8112292 |8188688 
|8479541 |8695800 
|8810325 |9009162 
|9344843 |9872323 
|10207103 |10319320 
|10477741 |10570290 
|10716926 |11960376 
|11964172 |11997436 
|12577067 
GRB2 interacts with SOS. This interaction was modeled on a demonstrated interaction between human GRB2 and mouse SOS.BIND7862111 
Sos1 interacts with Grb2. This interaction was modeled on a demonstrated interaction between Sos1 and Grb2 from Bos taurus.BIND9374537 
GRB2SOCS7-HPRD9344857 
GRB2EPOR-HPRD,BioGRID7534299 
GRB2MERTK-HPRD9891051 
GRB2LAT2-HPRD,BioGRID12514734 
GRB2BCRGrb2 interacts with Bcr-Abl.BIND9872323 
-HPRD,BioGRID8112292 |9178913 
Tyrosine phosphorylated Bcr-Abl interacts with Grb2.BIND8112292 
GRB2DRD4D4.7 interacts with Grb2.BIND9843378 
D4.4 interacts with Grb2.BIND9843378 
-HPRD,BioGRID9843378 
D4.2 interacts with Grb2.BIND9843378 
GRB2DRD3D3 interacts with Grb2.BIND9843378 
-HPRD,BioGRID11384839 
GRB2CHRM4M4 interacts with Grb2.BIND9843378 
GRB2USP6NLGrb2 interacts with RN-tre.BIND12399475 
-HPRD,BioGRID12399475 
GRB2SELL-HPRD,BioGRID8986819 
GRB2BCAR1-HPRD8649368 |8700507 
Affinity Capture-Western; Reconstituted ComplexBioGRID10085298 |10822386 
GRB2INSRAffinity Capture-WesternBioGRID9083103 
GRB2SH2B1-HPRD,BioGRID9856458 
GRB2CRKAffinity Capture-Western; Far Western; Reconstituted ComplexBioGRID8662907 |8810325 
|10970810 
-HPRD8662907 |10970810 
GRB2EGF-HPRD10973965 
GRB2FGFR1-HPRD9480847 
GRB2PTPN12-HPRD,BioGRID9135065 
GRB2ETV6Affinity Capture-Western; Far WesternBioGRID15143164 
GRB2CRKL-HPRD,BioGRID10477741 
GRB2INPP5D-HPRD,BioGRID8723348 
GRB2ABL1-HPRD9516488 
Affinity Capture-WesternBioGRID9407116 
GRB2TOM1L1-HPRD,BioGRID11711534 
GRB2DNM1Affinity Capture-Western; Far Western; Reconstituted ComplexBioGRID8119878 |9009162 
-HPRD8119878 |11877424 
GRB2PDE4DPDE4D4 interacts with Grb2. This interaction was modelled on a demonstrated interaction between human PDE4D4 and Grb2 from an unspecified species.BIND10571082 
GRB2DTX1-HPRD,BioGRID9590294 
GRB2ACTA1Affinity Capture-MSBioGRID12577067 
GRB2FASLG-HPRD,BioGRID11741599 |12023017 
CD95L interacts with Grb2.BIND12023017 
GRB2DRD4D4.7 interacts with Grb2.BIND9843378 
D4.4 interacts with Grb2.BIND9843378 
-HPRD,BioGRID9843378 
D4.2 interacts with Grb2.BIND9843378 
GRB2SHC1Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Reconstituted ComplexBioGRID7514169 |7524086 
|7535773 |8112292 
|8195171 |8294403 
|8491186 |8647288 
|8662733 |9045692 
|9083103 |9927207 
|10080542 |10477741 
|10570290 |11302736 
|11505033 |11964172 
|12441060 |12577067 
Shc interacts with Grb2. This interaction was modelled on a demonstrated interaction between Shc from human and Grb2 from rat and an unspecified species.BIND8084588 
-HPRD7524086 |7535773 
|8491186 |11707405 
An unspecified isoform of Grb2 interacts with the p52 isoform of Shc.BIND9148935 
Grb2 interacts with Shc.BIND7515480 |8112292 
|8939605 |10891441 
GRB2WASAffinity Capture-Western; Reconstituted ComplexBioGRID8805332 |9307968 
-HPRD9307968 |10224664 
GRB2IRS2-HPRD9852124 
GRB2LY6G6F-HPRD,BioGRID12852788 
GRB2SYNJ2-HPRD9388224 
GRB2FGFR3-HPRD,BioGRID9045692 
GRB2PDE6G-HPRD,BioGRID12624098 
GRB2PTK2Tyrosine-phosphorylated FAK interacts with Grb2.BIND7597091 
-HPRD7997267 
Affinity Capture-Western; Reconstituted ComplexBioGRID8649427 |10085298 
|10806474 |12005431 
|12558988 
Grb2 interacts with FAK. This interaction was modeled on a demonstrated interaction between human Grb2 and mouse FAK.BIND9148935 
GRB2MAPK12-HPRD9019171 
GRB2SGCA-HPRD7744812 
GRB2KITKit interacts with Grb2. This interaction was modeled on a demonstrated interaction between mouse proteins.BIND10022833 
Grb2 interacts with c-Kit upon stimulation with SLF. This interaction was modeled on a demonstrated interaction between mouse Grb2 and human c-Kit.BIND7523381 
-HPRD,BioGRID10377264 
GRB2EGFRGRB2 interacts with an unspecified isoform of EGFR. This interaction was modeled on a demonstrated interaction between human GRB2, and rat EGFR.BIND15782189 
-HPRD1322798 |7527043 
EGFR interacts with GRB2.BIND8305738 
Affinity Capture-MS; Affinity Capture-Western; Reconstituted ComplexBioGRID1322798 |7510700 
|7527043 |8647858 
|9050991 |10026169 
|10085134 |11960376 
|12577067 |16729043 
GRB2HCLS1Reconstituted ComplexBioGRID9670936 
GRB2SH3KBP1-HPRD9507006|11152963 
SETA interacts with Grb2. This interaction was modelled on a demonstrated interaction between rat SETA and human Grb2BIND11152963 
Reconstituted ComplexBioGRID10921882 |11152963 
GRB2OCRL-HPRD,BioGRID9038219 
GRB2ELK1-HPRD8798570 
GRB2ABL1-HPRD9516488 
Affinity Capture-WesternBioGRID9407116 
GRB2KITKit interacts with Grb2. This interaction was modeled on a demonstrated interaction between mouse proteins.BIND10022833 
Grb2 interacts with c-Kit upon stimulation with SLF. This interaction was modeled on a demonstrated interaction between mouse Grb2 and human c-Kit.BIND7523381 
-HPRD,BioGRID10377264 
GRB2DCTN1-HPRD,BioGRID8955163 
GRB2KRT8Affinity Capture-MSBioGRID12577067 
GRB2SH3KBP1-HPRD9507006|11152963 
SETA interacts with Grb2. This interaction was modelled on a demonstrated interaction between rat SETA and human Grb2BIND11152963 
Reconstituted ComplexBioGRID10921882 |11152963 
GRB2RAPGEF1-HPRD,BioGRID8621483 
GRB2SH3BP2-HPRD,BioGRID9846481 
GRB2SH2B3-HPRD,BioGRID8649391 
GRB2SHC1Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Reconstituted ComplexBioGRID7514169 |7524086 
|7535773 |8112292 
|8195171 |8294403 
|8491186 |8647288 
|8662733 |9045692 
|9083103 |9927207 
|10080542 |10477741 
|10570290 |11302736 
|11505033 |11964172 
|12441060 |12577067 
Shc interacts with Grb2. This interaction was modelled on a demonstrated interaction between Shc from human and Grb2 from rat and an unspecified species.BIND8084588 
-HPRD7524086 |7535773 
|8491186 |11707405 
An unspecified isoform of Grb2 interacts with the p52 isoform of Shc.BIND9148935 
Grb2 interacts with Shc.BIND7515480 |8112292 
|8939605 |10891441 
GRB2JUB-HPRD10330178 
GRB2SH3KBP1-HPRD9507006|11152963 
SETA interacts with Grb2. This interaction was modelled on a demonstrated interaction between rat SETA and human Grb2BIND11152963 
Reconstituted ComplexBioGRID10921882 |11152963 
GRB2BLNK-HPRD,BioGRID9697839 |9705962 
GRB2TNFRSF1A-HPRD,BioGRID10359574 
GRB2GAB3-HPRD,BioGRID11739737 
GRB2KDR-HPRD,BioGRID10319320 
GRB2FRS3-HPRD11432792 
GRB2KRT7Affinity Capture-MSBioGRID12577067 
GRB2MTA3-HPRD11483358 
GRB2CBLGrb2 interacts with Cbl.BIND15782196 
c-Cbl interacts with Grb2. This interaction was modeled on a demonstrated interaction between human c-Cbl and Grb2 from an unspecified species.BIND11053437 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID8083187 |9108392 
|9174058 |9178909 
|9367879 |9461587 
|9872323 |10086340 
|10204582 |10570290 
|11964172 |11997436 
-HPRD9108392 |9178909 
|11133830 |11964172 
GRB2ERBB2-HPRD11173924 |11606575|11606575 
-HPRD,BioGRID11606575 
GRB2GRLF1Affinity Capture-WesternBioGRID12441060 
GRB2ITK-HPRD,BioGRID10636929 
GRB2HNRNPC-HPRD,BioGRID9516488 
GRB2RET-HPRD9393871 
Reconstituted ComplexBioGRID7665556 |8183561 
GRB2PTK2Tyrosine-phosphorylated FAK interacts with Grb2.BIND7597091 
-HPRD7997267 
Affinity Capture-Western; Reconstituted ComplexBioGRID8649427 |10085298 
|10806474 |12005431 
|12558988 
Grb2 interacts with FAK. This interaction was modeled on a demonstrated interaction between human Grb2 and mouse FAK.BIND9148935 
GRB2GAB1-HPRD,BioGRID11314042 |11960376 
GRB2CDKN1B-HPRD,BioGRID11278754 
GRB2CTTN-HPRD11439336 
GRB2ARHGAP17Reconstituted ComplexBioGRID11431473 
GRB2GAB2Affinity Capture-Western; Reconstituted ComplexBioGRID10391903 |11782427 
|15143164 
-HPRD10068651 |11882361 
GRB2RET-HPRD9393871 
Reconstituted ComplexBioGRID7665556 |8183561 
GRB2WASF2-HPRD9307968 
GRB2MICAL1Reconstituted ComplexBioGRID11827972 
GRB2PTPN1-HPRD10660596 |12388170 
Reconstituted ComplexBioGRID8940134 |10660596 
GRB2FASLG-HPRD,BioGRID11741599 |12023017 
CD95L interacts with Grb2.BIND12023017 
GRB2MTA1-HPRD11483358 
GRB2SYK-HPRD,BioGRID11964172 
GRB2WASAffinity Capture-Western; Reconstituted ComplexBioGRID8805332 |9307968 
-HPRD9307968 |10224664 
GRB2WASL-HPRD,BioGRID10087612 |10781580 
GRB7PTK2-HPRD,BioGRID10446223 
GRB7RET-HPRD,BioGRID8631863 
GRB7LY6G6F-HPRD,BioGRID12852788 
GRB7INSR-HPRD,BioGRID10803466 
GRB7EGFR-HPRD9710451 
GRB7SFNAffinity Capture-MSBioGRID15778465 
GRB7ERBB3-HPRD,BioGRID9516479 
GRB7RND1-HPRD,BioGRID10664463 
GRB7KIT-HPRD,BioGRID10377264 
GRB7ERBB2-HPRD,BioGRID9079677 
GRB7CALM1Grb7 interacts with CaM. This interaction was modeled on a demonstrated interaction between human Grb7 and CaM from rat and an unspecified species.BIND15806159 
DOK2DNAJB11Affinity Capture-MSBioGRID17353931 
DOK2INPP5DSHIP1 interacts with Dok2BIND10822173 
Affinity Capture-WesternBioGRID10822173 
DOK2RASA1Affinity Capture-WesternBioGRID10822173 
Dok2 interacts with RASGAPBIND10822173 
-HPRD10508618 |10799545 
DOK2DOK1Affinity Capture-WesternBioGRID10822173 
DOK2RASA1Affinity Capture-WesternBioGRID10822173 
Dok2 interacts with RASGAPBIND10822173 
-HPRD10508618 |10799545 
DOK2SSSCA1Affinity Capture-MSBioGRID17353931 
DOK2KIAA1279Two-hybridBioGRID16189514 
DOK2CFLARAffinity Capture-MSBioGRID17353931 
DOK2NCK1-HPRD,BioGRID11689432 
DOK2ASF1BAffinity Capture-MSBioGRID17353931 
DOK2RAB10Affinity Capture-MSBioGRID17353931 
DOK2SHC1Affinity Capture-WesternBioGRID10822173 
DOK2RET-HPRD,BioGRID11470823 
DOK2EGFR-HPRD,BioGRID10508618 
DOK2INPP5DSHIP1 interacts with Dok2BIND10822173 
Affinity Capture-WesternBioGRID10822173 
DOK2PSMD10Affinity Capture-MSBioGRID17353931 
DOK2HSPA4LAffinity Capture-MSBioGRID17353931 
DOK2RASA1Affinity Capture-WesternBioGRID10822173 
Dok2 interacts with RASGAPBIND10822173 
-HPRD10508618 |10799545 
DOK2SPOPAffinity Capture-MSBioGRID17353931 
PIK3R1METMET (c-Met) interacts with PIK3R1. This interaction was modeled on a demonstrated interaction between human c-Met and PIK3R1 from an unspecified species.BIND15735664 
PIK3R1IRS2-HPRD,BioGRID9852124 |12107746 
PIK3R1SRC-HPRD12210743 
Affinity Capture-WesternBioGRID10487518 
PIK3R1NFKBIA-HPRD,BioGRID9892650 
PIK3R1JAK1-HPRD,BioGRID9774657 
PIK3R1DOK1Reconstituted ComplexBioGRID11071635 
PIK3R1FASLG-HPRD11741599 
PIK3R1SH3KBP1-HPRD,BioGRID10921882 
PIK3R1RRAS2-HPRD,BioGRID11850823 
PIK3R1GHR-HPRD,BioGRID9632636 
PIK3R1HRAS-HPRD,BioGRID10212255 
PIK3R1PIK3CAReconstituted ComplexBioGRID7929193 
PIK3R1SHBShb interacts with p85-alpha PI3 kinase. This interaction was modelled on a demonstrated interaction between human Shb and bovine p85-alpha PI3 kinase.BIND7537362 
-HPRD,BioGRID7537362 
PIK3R1CDC42-HPRD,BioGRID7629060 |8034624 
|9381982 
-HPRD9381982 
PIK3R1FCGR2A-HPRD,BioGRID8631888 
PIK3R1FYN-HPRD8394019 
Reconstituted ComplexBioGRID8294442 
PIK3R1CTLA4-HPRD7807015 
PIK3R1TGFBR1-HPRD,BioGRID9435577 
PIK3R1CBLBAffinity Capture-WesternBioGRID9614102 
PIK3R1INPP5DAffinity Capture-WesternBioGRID9918857 
PIK3R1KHDRBS1Affinity Capture-Western; Reconstituted ComplexBioGRID10467411 |11604231 
Sam68 interacts with the SH2 domains of PI3K p85 alpha. This interaction was modelled based on a demonstrated interaction between two rat proteins.BIND7537265 |10437794 
|11604231 
PIK3R1PIK3CB-HPRD,BioGRID8139559 |10358930 
PIK3R1TRAT1-HPRD10723796 
PIK3R1VAV1-HPRD7528218 |9891995 
Affinity Capture-Western; Reconstituted ComplexBioGRID9162069 |9891995 
PIK3R1SHC1Reconstituted ComplexBioGRID7537361 
p85 interacts with Shc.BIND8662998 
-HPRD8662998 
PIK3R1HNRNPKp85 interacts with hnRNPK. This interaction was modeled on a demonstrated interaction between p85 from an unspecified source and human hnRNPK.BIND8810341 
PIK3R1EPHA2Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID7982920 
PIK3R1CRKLAffinity Capture-WesternBioGRID9461587 
PIK3R1MST1R-HPRD8918464 
PIK3R1CD22-HPRD8647200 
PIK3R1ABL1c-Abl interacts with p85. This interaction was modeled on a demonstrated interaction between human c-Abl and bovine p85.BIND1383690 
Reconstituted ComplexBioGRID8294442 
PIK3R1EZR-HPRD,BioGRID10377409 
PIK3R1WASAffinity Capture-Western; Reconstituted ComplexBioGRID8805332 
-HPRD10358777 
PIK3R1PTPN6Two-hybridBioGRID11160222 
-HPRD11337495 
PIK3R1IRS1Affinity Capture-Western; Far WesternBioGRID1381348 |12107746 
|12173038 |12730242 
-HPRD1381348 |12173038 
-HPRD12220227 
PIK3R1CD28-HPRD,BioGRID7737275 |8621607 
PIK3R1AXLBiochemical ActivityBioGRID9178760 
Axl interacts with an unspecified isoform of p85-alpha.BIND12470648 
PIK3R1IGF1R-HPRD,BioGRID8697095 
PIK3R1IL1RAP-HPRD,BioGRID10373529 
PIK3R1RAC1-HPRD7629060 |8034624 
|12086876 
-HPRD12086876 
PIK3R1ARHGAP17Reconstituted ComplexBioGRID11431473 
PIK3R1PXNCo-purificationBioGRID8641358 
PIK3R1IL6STAffinity Capture-WesternBioGRID10579793 
PIK3R1ERAS-HPRD12774123 
PIK3R1CSF1R-HPRD,BioGRID8947469 
CSF1R (c-FMS) interacts with PIK3R1 (PI3'-k).his interaction was modeled on a demonstrated interaction between CSF1R and PIK3R1 from unspecified species.BIND15735664 
PIK3R1IRS4-HPRD11912194 
PIK3R1CSF2RA-HPRD,BioGRID12538575 
PIK3R1MME-HPRD12529960 
PIK3R1WBP11-HPRD11375989 
PIK3R1GAB2Affinity Capture-Western; Two-hybridBioGRID11334882 |11782427 
-HPRD10068651 
PIK3R1EGFR-HPRD8662998 
EGFR interacts with p85. This interaction was modeled on a demonstrated interaction between human EGFR and bovine p85.BIND1372092 
PIK3R1PTPN6Two-hybridBioGRID11160222 
-HPRD11337495 
PIK3R1GAB2Affinity Capture-Western; Two-hybridBioGRID11334882 |11782427 
-HPRD10068651 
PIK3R1NTRK2Two-hybridBioGRID12074588 
PIK3R1IFNAR1-HPRD,BioGRID10542297 
PIK3R1TUBG1-HPRD7592789 
PIK3R1EPOR-HPRD,BioGRID7559499 
PIK3R1GAB3-HPRD11739737 
PIK3R1CD7-HPRD,BioGRID8918688 
PIK3R1ESR1-HPRD,BioGRID11689445 
PIK3R1RB1Rb interacts with p55alphaBIND12588990 
PIK3R1ARHGAP1-HPRD,BioGRID8253717 
PIK3R1VAV1-HPRD7528218 |9891995 
Affinity Capture-Western; Reconstituted ComplexBioGRID9162069 |9891995 
PIK3R1CD5-HPRD,BioGRID9079809 
PIK3R1LATAffinity Capture-Western; Reconstituted ComplexBioGRID11368773 
PIK3R1IL1R1-HPRD,BioGRID9360994 |10373529 
PIK3R1HGS-HPRD10970851 
PIK3R1KITKit interacts with p85-alpha. This interaction was modeled on a demonstrated interaction between mouse proteinsBIND10022833 
-HPRD,BioGRID7509796 
PIK3R1JAK2-HPRD,BioGRID8702385 
PIK3R1IRS1Affinity Capture-Western; Far WesternBioGRID1381348 |12107746 
|12173038 |12730242 
-HPRD1381348 |12173038 
-HPRD12220227 
PIK3R1GNAQAffinity Capture-WesternBioGRID12704201 
PIK3R1PTK2B-HPRD10797305 
PIK3R1TYRO3-HPRD,BioGRID10627473 
PIK3R1PTK2-HPRD,BioGRID7537275 |8649427 
|10806474 
PIK3R1ERBB3-HPRD,BioGRID10383151 |11546794 
PIK3R1INSRINSR (IR) interacts with PIK3R1. This interaction was modeled on a demonstrated interaction between INSR and PIK3R1 from unspecified species.BIND15735664 
The insulin receptor (IR) interacts with p85-alpha.BIND8603569 
PIK3R1GAB1Affinity Capture-Western; Far Western; Reconstituted ComplexBioGRID8596638 |9891995 
PIK3R1HCSTProtein-peptideBioGRID10426994 
PIK3R1RICS-HPRD,BioGRID12454018 
PIK3R1PDGFRBin vivoBioGRID10697503 
Beta-PDGFR interacts with p85. This interaction was modeled on a demonstrated interaction between human beta-PDGFR and rat or bovine p85.BIND1372092 |7689724 
|7876130 
Phosphorylated beta-PDGFR interacts with p85-alpha. This interaction was modeled on a demonstrated interaction between human beta-PDGFR and bovine p85-alpha.BIND8388538 
PIK3R1INSRINSR (IR) interacts with PIK3R1. This interaction was modeled on a demonstrated interaction between INSR and PIK3R1 from unspecified species.BIND15735664 
The insulin receptor (IR) interacts with p85-alpha.BIND8603569 
PIK3R1CBLAffinity Capture-WesternBioGRID9461587 |9918857 
PIK3R1ARAF-HPRD,BioGRID11812000 
PIK3R1TUBA1B-HPRD,BioGRID7592789 
PIK3R1AXLBiochemical ActivityBioGRID9178760 
Axl interacts with an unspecified isoform of p85-alpha.BIND12470648 
PIK3R1KITKit interacts with p85-alpha. This interaction was modeled on a demonstrated interaction between mouse proteinsBIND10022833 
-HPRD,BioGRID7509796 
PIK3R1RAC1-HPRD7629060 |8034624 
|12086876 
-HPRD12086876 
PIK3R1ADAM12-HPRD,BioGRID11313349 
PIK3R1SLC9A2-HPRD10187839 
PIK3R1RASA1-HPRD1336372 
PIK3R1IL2RB-HPRD,BioGRID9774657 
PIK3R1PDGFRBin vivoBioGRID10697503 
Beta-PDGFR interacts with p85. This interaction was modeled on a demonstrated interaction between human beta-PDGFR and rat or bovine p85.BIND1372092 |7689724 
|7876130 
Phosphorylated beta-PDGFR interacts with p85-alpha. This interaction was modeled on a demonstrated interaction between human beta-PDGFR and bovine p85-alpha.BIND8388538 
PIK3R1CTNNB1Reconstituted ComplexBioGRID10477752 
-HPRD11716761 
PIK3R1PDGFRBin vivoBioGRID10697503 
Beta-PDGFR interacts with p85. This interaction was modeled on a demonstrated interaction between human beta-PDGFR and rat or bovine p85.BIND1372092 |7689724 
|7876130 
Phosphorylated beta-PDGFR interacts with p85-alpha. This interaction was modeled on a demonstrated interaction between human beta-PDGFR and bovine p85-alpha.BIND8388538 
PIK3R1TLN1Co-purificationBioGRID8641358 
PIK3R1FYN-HPRD8394019 
Reconstituted ComplexBioGRID8294442 
PIK3R1CD3E-HPRD,BioGRID9312149 |11689561 
|11855827 
PIK3R1WASAffinity Capture-Western; Reconstituted ComplexBioGRID8805332 
-HPRD10358777 
PIK3R1EGFR-HPRD8662998 
EGFR interacts with p85. This interaction was modeled on a demonstrated interaction between human EGFR and bovine p85.BIND1372092 
PIK3R1ERBB2-HPRD1351056 
PIK3R1RET-HPRD10652352 
PIK3R1BCAR1-HPRD,BioGRID10799562 
PIK3R1AGAP2-HPRD,BioGRID11136977 
PIK3R1FLT1Flt-1 interacts with p85.BIND7657594 
PIK3R1TGFBR2Affinity Capture-WesternBioGRID9435577 
PIK3R1SYN1-HPRD,BioGRID10899172 
PIK3R1SRC-HPRD12210743 
Affinity Capture-WesternBioGRID10487518 
PIK3R1CSF1R-HPRD,BioGRID8947469 
CSF1R (c-FMS) interacts with PIK3R1 (PI3'-k).his interaction was modeled on a demonstrated interaction between CSF1R and PIK3R1 from unspecified species.BIND15735664 
PIK3R1LCP2Affinity Capture-Western; Two-hybridBioGRID15388330 
PIK3R1PIK3CD-HPRD,BioGRID9113989 
PIK3R1SHBShb interacts with p85-alpha PI3 kinase. This interaction was modelled on a demonstrated interaction between human Shb and bovine p85-alpha PI3 kinase.BIND7537362 
-HPRD,BioGRID7537362 
PIK3R1VAV3-HPRD11094073 
PIK3R1ABL1c-Abl interacts with p85. This interaction was modeled on a demonstrated interaction between human c-Abl and bovine p85.BIND1383690 
Reconstituted ComplexBioGRID8294442 
PIK3R1CD4-HPRD8246987 
PIK3R1CDC42-HPRD,BioGRID7629060 |8034624 
|9381982 
-HPRD9381982 
PIK3R1KHDRBS1Affinity Capture-Western; Reconstituted ComplexBioGRID10467411 |11604231 
Sam68 interacts with the SH2 domains of PI3K p85 alpha. This interaction was modelled based on a demonstrated interaction between two rat proteins.BIND7537265 |10437794 
|11604231 
PIK3R1SHC1Reconstituted ComplexBioGRID7537361 
p85 interacts with Shc.BIND8662998 
-HPRD8662998 
PIK3R1IL13-HPRD9139718 
PIK3R1CHRNA7-HPRD11278378 
PIK3R1TOM1L1-HPRD11711534 
PIK3R1CD2AP-HPRD10339567 
PIK3R1FES-HPRD,BioGRID8916957 
PIK3R1IRS1Affinity Capture-Western; Far WesternBioGRID1381348 |12107746 
|12173038 |12730242 
-HPRD1381348 |12173038 
-HPRD12220227 
PIK3R1SHC1Reconstituted ComplexBioGRID7537361 
p85 interacts with Shc.BIND8662998 
-HPRD8662998 
PIK3R1CD19-HPRD7528218 
PIK3R1PECAM1Affinity Capture-WesternBioGRID9774384 
PIK3R1CTNNB1Reconstituted ComplexBioGRID10477752 
-HPRD11716761 
SOCS1JAK2-HPRD9202126 |10064597 
|11971965 
Affinity Capture-Western; in vitro; in vivo; Reconstituted Complex; Two-hybridBioGRID9202126 |10064597 
|10455112 |11713228 
|11971965 
SOCS1JAK1-HPRD11133764 
SOCS1VAV1-HPRD,BioGRID10022833 
Socs1 interacts with Vav. This interaction was modeled on a demonstrated interaction between mouse Socs1 and Vav.BIND10022833 
SOCS1IGF1R-HPRD,BioGRID9727029 
Insulin-like Growth Factor-I Receptor interacts with SOCS1BIND9727029 
SOCS1AXLAxl interacts with SOCS-1.BIND12470648 
SOCS1INSRSuppressors of cytokine signaling-1 associates with and inhibits the insulin receptor.BIND11342531 
SOCS1IGF1R-HPRD,BioGRID9727029 
Insulin-like Growth Factor-I Receptor interacts with SOCS1BIND9727029 
SOCS1IL2RB-HPRD,BioGRID11133764 
SOCS1CSF1R-HPRD,BioGRID10022833 |11297560 
Socs1 interacts with CSF1-R. This interaction was modeled on a demonstrated interaction between mouse proteins.BIND10022833 
SOCS1PDGFRBSocs1 interacts with PDGF-R. This interaction was modeled on a demonstrated interaction between mouse Socs1 and human PDGF-R.BIND10022833 
SOCS1NCK1Socs1 interacts with Nck. This interaction was modeled on a demonstrated interaction between mouse Socs1 and Nck from an unspecified species.BIND10022833 
-HPRD,BioGRID10022833 
SOCS1FYNSocs1 interacts with Fyn. This interaction was modeled on a demonstrated interaction between mouse Socs1 and Fyn from an unspecified species.BIND10022833 
-HPRD,BioGRID10022833 
SOCS1EGFR-HPRD,BioGRID12070153 
SOCS1CSF1R-HPRD,BioGRID10022833 |11297560 
Socs1 interacts with CSF1-R. This interaction was modeled on a demonstrated interaction between mouse proteins.BIND10022833 
SOCS1KIT-HPRD,BioGRID10022833 
Socs1 interacts with Kit. This interaction was modeled on a demonstrated interaction between mouse proteinsBIND10022833 
SOCS1ITKSocs1 interacts with Itk. This interaction was modeled on a demonstrated interaction between mouse Socs1 and Itk from an unspecified species.BIND10022833 
-HPRD,BioGRID10022833 
SOCS1FYNSocs1 interacts with Fyn. This interaction was modeled on a demonstrated interaction between mouse Socs1 and Fyn from an unspecified species.BIND10022833 
-HPRD,BioGRID10022833 
SOCS1VAV1-HPRD,BioGRID10022833 
Socs1 interacts with Vav. This interaction was modeled on a demonstrated interaction between mouse Socs1 and Vav.BIND10022833 
SOCS1PIK3R2Socs1 interacts with p85-beta. This interaction was modeled on a demonstrated interaction between mouse Socs1 and p85-beta from an unspecified species.BIND10022833 
SOCS1MPLAffinity Capture-WesternBioGRID10517496 
SOCS1JAK2-HPRD9202126 |10064597 
|11971965 
Affinity Capture-Western; in vitro; in vivo; Reconstituted Complex; Two-hybridBioGRID9202126 |10064597 
|10455112 |11713228 
|11971965 
SOCS1IRS1-HPRD,BioGRID11208867 |12228220 
SOCS1CSF1-HPRD11297560 
SOCS1NCK1Socs1 interacts with Nck. This interaction was modeled on a demonstrated interaction between mouse Socs1 and Nck from an unspecified species.BIND10022833 
-HPRD,BioGRID10022833 
SOCS1CRKReconstituted ComplexBioGRID10022833 
SOCS1ITKSocs1 interacts with Itk. This interaction was modeled on a demonstrated interaction between mouse Socs1 and Itk from an unspecified species.BIND10022833 
-HPRD,BioGRID10022833 
SOCS1IRS2Affinity Capture-WesternBioGRID12228220 
SOCS1KIT-HPRD,BioGRID10022833 
Socs1 interacts with Kit. This interaction was modeled on a demonstrated interaction between mouse proteinsBIND10022833 
SOCS1VAV2-HPRD,BioGRID10022833 
Socs1 interacts with Vav2. This interaction was modeled on a demonstrated interaction between mouse Socs1 and human Vav2.BIND10022833 
SOCS1TRIM8-HPRD12163497 
SOCS1JAK3-HPRD11133764 
SOCS1TCEB3Affinity Capture-WesternBioGRID10051596 
SOCS1TCEB1-HPRD,BioGRID10051596 
SOCS1VAV2-HPRD,BioGRID10022833 
Socs1 interacts with Vav2. This interaction was modeled on a demonstrated interaction between mouse Socs1 and human Vav2.BIND10022833 
SOCS1TCEB2-HPRD10051596 
SOCS1FLT3Socs1 interacts with Flt3. This interaction was modeled on a demonstrated interaction between mouse Socs1 and Flt3.BIND10022833 
-HPRD,BioGRID10022833 
SOCS1FLT3Socs1 interacts with Flt3. This interaction was modeled on a demonstrated interaction between mouse Socs1 and Flt3.BIND10022833 
-HPRD,BioGRID10022833 
SOCS1GHR-HPRD,BioGRID10585430 
SOCS1TEC-HPRD,BioGRID9341160 
GRB14PDGFRB-HPRD,BioGRID8647858 
GRB14FTCDCo-fractionationBioGRID11278563 
GRB14INSR-HPRD,BioGRID9748281 |11726652 
GRB14FGFR1-HPRD,BioGRID10713090 
GRB14PDGFRA-HPRD8647858 
GRB14PRKCZ-HPRD,BioGRID12242277 
GRB14TNKS2-HPRD,BioGRID11278563 
GRB14EGFR-HPRD,BioGRID8647858 
GRB14DAPK3Reconstituted ComplexBioGRID12242277 


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