Protein-protein interaction for USP7

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Nodes, degree=1 Nodes, degree=2


Protein-protein interaction data for gene USP7

Degree = 1
Interactor A Interactor B Experimental method Source Pubmed
USP7TRAF3-HPRD,BioGRID11279055 
-HPRD,BioGRID11279055 
USP7TRAF1-HPRD,BioGRID11279055 
-HPRD,BioGRID11279055 
USP7MDM4Hdmx interacts with HAUSP.BIND15916963 
Hdmx interacts with HAUSP.BIND15916963 
USP7TANK-HPRD,BioGRID11279055 
-HPRD,BioGRID11279055 
USP7MAGEB2Affinity Capture-MSBioGRID17353931 
Affinity Capture-MSBioGRID17353931 
USP7RUVBL2Affinity Capture-MSBioGRID17353931 
Affinity Capture-MSBioGRID17353931 
USP7TRAF5-HPRD,BioGRID11279055 
-HPRD,BioGRID11279055 
USP7TRAF6-HPRD,BioGRID11279055 
-HPRD,BioGRID11279055 
USP7TRAF4-HPRD,BioGRID11279055 
-HPRD,BioGRID11279055 
USP7RNPS1Affinity Capture-MSBioGRID17353931 
Affinity Capture-MSBioGRID17353931 
USP7TP53-HPRD,BioGRID11923872 
p53 interacts with HAUSP.BIND15916963 
-HPRD,BioGRID11923872 
p53 interacts with HAUSP.BIND15916963 
USP7MDM2Mdm2 interacts with HAUSP. This interaction was modeled on a demonstrated interaction between Mdm2 from an unspecified species and human HAUSP.BIND15916963 
Mdm2 interacts with HAUSP. This interaction was modeled on a demonstrated interaction between Mdm2 from an unspecified species and human HAUSP.BIND15916963 
USP7USP7-HPRD12507430 
-HPRD12507430 
USP7TRAF2-HPRD,BioGRID11279055 
-HPRD,BioGRID11279055 
USP7ATXN1-HPRD,BioGRID12093161 
-HPRD,BioGRID12093161 

Degree = 2
Interactor A Interactor B Experimental method Source Pubmed
TRAF3TRAF3IP3-HPRD14572659 
TRAF3RIPK1-HPRD,BioGRID8612133 
TRAF3TNFRSF18-HPRD,BioGRID10037686 
TRAF3TNFRSF8CRAF1 interacts with CD30.BIND8662842 
-HPRD,BioGRID8943059 
TRAF3SRCAffinity Capture-WesternBioGRID10635328 
TRAF3TNFRSF14-HPRD,BioGRID9162022 
TRAF3TNFRSF11A-HPRD,BioGRID9774460 |9852070 
|10025951 
TRAF3TTRAPAffinity Capture-WesternBioGRID10764746 
TRAF3TNFRSF4-HPRD9418902 
TRAF3TRAF3IP2-HPRD,BioGRID12089335 
TRAF3MAP3K5Affinity Capture-WesternBioGRID9774977 
TRAF3CD40-HPRD7527023 |7530216 
|7533327 |10984535 
Affinity Capture-Western; Co-crystal Structure; Reconstituted Complex; Two-hybridBioGRID7527023 |9384571 
|9990007 |10984535 
CD40 interacts with TRAF3.BIND10352240 
-HPRD7527023 |7533327 
|10984535 
TRAF3LTBR-HPRD,BioGRID9122217 
TRAF3 interacts with LTBR.BIND12571250 
TRAF3TNFSF14Affinity Capture-MS; Affinity Capture-WesternBioGRID12571250 
TRAF3TRAF3IP1-HPRD,BioGRID10791955 
TRAF3MAP3K14-HPRD,BioGRID11278268 
NIK interacts with TRAF3. This interaction was modeled on a demonstrated interaction between human NIK and TRAF3 from an unspecified species.BIND9275204 
TRAF3CFLARAffinity Capture-WesternBioGRID10837247 
TRAF3ACTA1-HPRD11950878 
TRAF3CD27-HPRD,BioGRID9582383 |9794406 
TRAF3TNFRSF17-HPRD,BioGRID10903733 
TRAF3TNFRSF9-HPRD,BioGRID9464265 
TRAF3CD40-HPRD7527023 |7530216 
|7533327 |10984535 
Affinity Capture-Western; Co-crystal Structure; Reconstituted Complex; Two-hybridBioGRID7527023 |9384571 
|9990007 |10984535 
CD40 interacts with TRAF3.BIND10352240 
-HPRD7527023 |7533327 
|10984535 
TRAF3CAP1-HPRD8761950 
TRAF3NUP62in vitro; in vivo; Two-hybridBioGRID10781837 
TRAF3TNFRSF12A-HPRD11728344 
TRAF3CD40-HPRD7527023 |7530216 
|7533327 |10984535 
Affinity Capture-Western; Co-crystal Structure; Reconstituted Complex; Two-hybridBioGRID7527023 |9384571 
|9990007 |10984535 
CD40 interacts with TRAF3.BIND10352240 
-HPRD7527023 |7533327 
|10984535 
TRAF3TNFRSF8CRAF1 interacts with CD30.BIND8662842 
-HPRD,BioGRID8943059 
TRAF3MAP3K14-HPRD,BioGRID11278268 
NIK interacts with TRAF3. This interaction was modeled on a demonstrated interaction between human NIK and TRAF3 from an unspecified species.BIND9275204 
TRAF3GRIN1-HPRD10862698 
TRAF3TRADD-HPRD8565075 
TRAF3RRAS2-HPRD10557073 
TRAF3LTBR-HPRD,BioGRID9122217 
TRAF3 interacts with LTBR.BIND12571250 
TRAF3CD40-HPRD7527023 |7530216 
|7533327 |10984535 
Affinity Capture-Western; Co-crystal Structure; Reconstituted Complex; Two-hybridBioGRID7527023 |9384571 
|9990007 |10984535 
CD40 interacts with TRAF3.BIND10352240 
-HPRD7527023 |7533327 
|10984535 
TRAF3CASP3-HPRD,BioGRID11261798 
TRAF3EDA2RAffinity Capture-WesternBioGRID12270937 
TRAF3MAP2K1-HPRD8626767 
TRAF3TRIM37-HPRD,BioGRID11279055 
TRAF3TNFRSF19-HPRD,BioGRID10809768 
TRAF3NGFRAffinity Capture-WesternBioGRID10514511 
TRAF1HSPA8-HPRD14743216 
TRAF1CD27Affinity Capture-WesternBioGRID9794406 
TRAF1MAP6in vitroBioGRID11279055 
TRAF1TNFAIP3-HPRD,BioGRID8692885 
TRAF1BIRC2c-IAP1 interacts with TRAF1.BIND11907583 
-HPRD,BioGRID9384571 |11907583 
TRAF1TNFRSF19-HPRD,BioGRID10809768 
TRAF1BIRC3-HPRD,BioGRID11907583 
c-IAP2 interacts with TRAF1.BIND11907583 
TRAF1TNFRSF9-HPRD,BioGRID9464265 
TRAF1CASP6Biochemical ActivityBioGRID11098060 
TRAF1TNFRSF12A-HPRD,BioGRID11728344 
TRAF1TNFRSF17-HPRD,BioGRID10903733 
TRAF1TNFRSF8-HPRD,BioGRID8627180 |8943059 
|9168896|8943059 
-HPRD8943059 
TRAF1 interacts with CD30.BIND8662842 
TRAF1TNFRSF11A-HPRD,BioGRID9774460 |9852070 
|10025951 
TRAF1RIPK2-HPRD,BioGRID9705938 
TRAF1BIRC3-HPRD,BioGRID11907583 
c-IAP2 interacts with TRAF1.BIND11907583 
TRAF1CFLAR-HPRD,BioGRID9208847 
TRAF1TNFRSF1B-HPRD8069916 
Reconstituted ComplexBioGRID9162022 
TRAF1TRIM37-HPRD,BioGRID11279055 
TRAF1TRAIP-HPRD,BioGRID9104814 
TRAF1TNFRSF18-HPRD,BioGRID10037686 
TRAF1SRCAffinity Capture-WesternBioGRID10635328 
TRAF1CASP10Biochemical ActivityBioGRID11098060 
TRAF1HIVEP3-HPRD,BioGRID11804591 
TRAF1TNFRSF14-HPRD,BioGRID9162022 
TRAF1NGFRAffinity Capture-WesternBioGRID10514511 
TRAF1CD40-HPRD7527023 |10411888 
TRAF1TRADD-HPRD,BioGRID8565075 
TRAF1RIPK1-HPRD,BioGRID8612133 
TRAF1RPS3-HPRD14743216 
TRAF1BIRC2c-IAP1 interacts with TRAF1.BIND11907583 
-HPRD,BioGRID9384571 |11907583 
TRAF1TNFRSF8-HPRD,BioGRID8627180 |8943059 
|9168896|8943059 
-HPRD8943059 
TRAF1 interacts with CD30.BIND8662842 
TRAF1TNFRSF1B-HPRD8069916 
Reconstituted ComplexBioGRID9162022 
TRAF1SPOP-HPRD11279055 
TRAF1TNFRSF1A-HPRD,BioGRID8565075 
TRAF1TNFRSF8-HPRD,BioGRID8627180 |8943059 
|9168896|8943059 
-HPRD8943059 
TRAF1 interacts with CD30.BIND8662842 
TRAF1TNFSF9-HPRD,BioGRID9418902 |9607925 
TRAF1TUBA3C-HPRD14743216 
TRAF1CASP8Affinity Capture-Western; Biochemical ActivityBioGRID11098060 |12887920 
TRAF1LTBRReconstituted ComplexBioGRID9162022 
TRAF1MAP3K14-HPRD,BioGRID11278268 
NIK interacts with TRAF1. This interaction was modeled on a demonstrated interaction between human NIK and TRAF1 from an unspecified species.BIND9275204 
TRAF1MAP3K5Affinity Capture-WesternBioGRID9774977 
TRAF1APIP-HPRD14743216 
TRAF1CASP3-HPRD11098060 
TRAF1MAP3K14-HPRD,BioGRID11278268 
NIK interacts with TRAF1. This interaction was modeled on a demonstrated interaction between human NIK and TRAF1 from an unspecified species.BIND9275204 
MDM4SMAD3-HPRD,BioGRID12483531 
MDM4E2F1-HPRD,BioGRID12532331 
E2F-1 interacts with MDMX. This interaction was modeled on a demonstrated interaction between human E2F-1 and mouse MDMX.BIND12532331 
MDM4SMAD4Reconstituted ComplexBioGRID12483531 
MDM4CDKN2AAffinity Capture-WesternBioGRID11297540 
MDM4CDC2CDC2 interacts with MDM4 (MDMX). This interaction was modeled on a demonstrated interaction between human CDC2, and MDM4 from an unspecified species.BIND15735705 
MDM4ARF1-HPRD11297540 
MDM4E2F1-HPRD,BioGRID12532331 
E2F-1 interacts with MDMX. This interaction was modeled on a demonstrated interaction between human E2F-1 and mouse MDMX.BIND12532331 
MDM4RB1pRb interacts with MDMX. This interaction was modeled on a demonstrated interaction between mouse MDMX and human pRb.BIND12532331 
MDM4UBE2D1Reconstituted ComplexBioGRID12393902 
MDM4EP300-HPRD,BioGRID12483531 
TANKITGB1BP1Affinity Capture-WesternBioGRID8710854 
TANKTUBA3C-HPRD14743216 
TANKIKBKG-HPRD,BioGRID12133833 
IKK-gamma interacts with TANK.BIND12133833 
TANKIKBKG-HPRD,BioGRID12133833 
IKK-gamma interacts with TANK.BIND12133833 
TANKIKBKE-HPRD,BioGRID10759890 
IKK-epsilon interacts with TANK.BIND12133833 
TANKTBK1-HPRD,BioGRID10581243 
TANKCHUKIKK-alpha interacts with TANK.BIND12133833 
Affinity Capture-WesternBioGRID12133833 
TANK interacts with IKK-alpha.BIND12133833 
TANKMAP4K5-HPRD10490605 
TANKIKBKE-HPRD,BioGRID10759890 
IKK-epsilon interacts with TANK.BIND12133833 
TANKCHUKIKK-alpha interacts with TANK.BIND12133833 
Affinity Capture-WesternBioGRID12133833 
TANK interacts with IKK-alpha.BIND12133833 
TANKZC3H12ATwo-hybridBioGRID16189514 
TANKHSPA8-HPRD14743216 
TANKCHUKIKK-alpha interacts with TANK.BIND12133833 
Affinity Capture-WesternBioGRID12133833 
TANK interacts with IKK-alpha.BIND12133833 
TANKIKBKB-HPRD12133833 
TANKHNRNPM-HPRD14743216 
MAGEB2RPS3AAffinity Capture-MSBioGRID17353931 
MAGEB2RPL31Affinity Capture-MSBioGRID17353931 
MAGEB2CSNK2BAffinity Capture-MSBioGRID17353931 
MAGEB2RPL23AAffinity Capture-MSBioGRID17353931 
MAGEB2RPS14Affinity Capture-MSBioGRID17353931 
MAGEB2RPS9Affinity Capture-MSBioGRID17353931 
MAGEB2RPL28Affinity Capture-MSBioGRID17353931 
MAGEB2RPL36AAffinity Capture-MSBioGRID17353931 
MAGEB2RPS26Affinity Capture-MSBioGRID17353931 
MAGEB2RPL26Affinity Capture-MSBioGRID17353931 
MAGEB2LXNAffinity Capture-MSBioGRID17353931 
MAGEB2RPL21Affinity Capture-MSBioGRID17353931 
MAGEB2RPS16Affinity Capture-MSBioGRID17353931 
MAGEB2RPL34Affinity Capture-MSBioGRID17353931 
MAGEB2RPL36Affinity Capture-MSBioGRID17353931 
MAGEB2RPS19Affinity Capture-MSBioGRID17353931 
MAGEB2RPS11Affinity Capture-MSBioGRID17353931 
RUVBL2RELA-HPRD14743216 
RUVBL2TBK1-HPRD14743216 
RUVBL2STAP1Affinity Capture-MSBioGRID14615539 
RUVBL2SSSCA1Affinity Capture-MSBioGRID17353931 
RUVBL2C19orf2-HPRD14615539 
RUVBL2CD82RUVBL2 (reptin) interacts with the CD82 (KAI1) promoter.BIND15829968 
RUVBL2NFKBIE-HPRD14743216 
RUVBL2MAP3K7IP2-HPRD14743216 
RUVBL2HDAC5RUVBL2 (reptin) interacts with an unspecified isoform of HDAC5.BIND15829968 
RUVBL2NOP5/NOP58-HPRD12417735 
RUVBL2PCNAAffinity Capture-MSBioGRID12171929 
RUVBL2MYCCo-purificationBioGRID11839798 
RUVBL2RIOK3Affinity Capture-MSBioGRID17353931 
RUVBL2MAP3K14-HPRD14743216 
RUVBL2PLOD2Affinity Capture-MSBioGRID17353931 
RUVBL2NFKB1-HPRD14743216 
NFKB1 (p50) interacts with RUVBL2 (reptin).BIND15829968 
RUVBL2CTNNB1CTNNB1 (beta-catenin) interacts with RUVBL2 (reptin).BIND15829968 
RUVBL2BCL3RUVBL2 (reptin) interacts with BCL3.BIND15829968 
RUVBL2EP400Affinity Capture-MSBioGRID11509179 
RUVBL2HDAC4RUVBL2 (reptin) interacts with HDAC4.BIND15829968 
RUVBL2MAP3K3-HPRD14743216 
RUVBL2MAP3K7-HPRD14743216 
RUVBL2NFKB1-HPRD14743216 
NFKB1 (p50) interacts with RUVBL2 (reptin).BIND15829968 
RUVBL2C2orf44Affinity Capture-MSBioGRID17353931 
RUVBL2NEK6Affinity Capture-MSBioGRID17353931 
RUVBL2FDFT1Two-hybridBioGRID16169070 
RUVBL2UQCRC1Affinity Capture-MSBioGRID17353931 
RUVBL2RGS20Affinity Capture-MSBioGRID17353931 
RUVBL2DNASE2Affinity Capture-MSBioGRID17353931 
RUVBL2ATF2-HPRD,BioGRID11713276 
RUVBL2RP11-529I10.4Affinity Capture-MS; Two-hybridBioGRID16189514 |17353931 
RUVBL2HDAC1RUVBL2 (reptin) interacts with HDAC1.BIND15829968 
RUVBL2IKBKEAffinity Capture-MSBioGRID17353931 
RUVBL2RPS11Affinity Capture-MSBioGRID17353931 
RUVBL2RUVBL1Affinity Capture-MSBioGRID17353931 
RUVBL2NME2Affinity Capture-MSBioGRID17353931 
RUVBL2NFKB2-HPRD14743216 
RUVBL2FASRUVBL2 (reptin) interacts with the FAS promoter.BIND15829968 
RUVBL2BCAS1Affinity Capture-MSBioGRID17353931 
RUVBL2PON2Affinity Capture-MSBioGRID17353931 
TRAF5RIPK1-HPRD,BioGRID11479302 
TRAF5TRIM37-HPRD,BioGRID11279055 
TRAF5TTRAP-HPRD,BioGRID10764746 
TRAF5MAP3K5-HPRD,BioGRID10523862 
TRAF5MAP3K14NIK interacts with TRAF5. This interaction was modeled on a demonstrated interaction between human NIK and TRAF5 from an unspecified species.BIND9275204 
TRAF5RIPK2-HPRD,BioGRID9642260 
TRAF5NGFRAffinity Capture-WesternBioGRID10514511 
TRAF5TNFRSF11A-HPRD9774460 |10025951 
Reconstituted ComplexBioGRID9685412 |9852070 
|10075662 
TRAF5CD27-HPRD,BioGRID9582383 
TRAF5TNFRSF8-HPRD,BioGRID8943059 |8999898 
-HPRD8943059 |8999898|8999898 
|11971184 
TRAF5TNFRSF13B-HPRD,BioGRID10880535 
TRAF5CD40-HPRD,BioGRID8790348 |9990007 
TRAF5LTBRReconstituted ComplexBioGRID9162022 
-HPRD8663299 
TRAF5TNFRSF19-HPRD,BioGRID10809768 
TRAF5TNFRSF4-HPRD,BioGRID9488716 
TRAF5TNFRSF8-HPRD,BioGRID8943059 |8999898 
-HPRD8943059 |8999898|8999898 
|11971184 
TRAF5LTBRReconstituted ComplexBioGRID9162022 
-HPRD8663299 
TRAF5TNFRSF11A-HPRD9774460 |10025951 
Reconstituted ComplexBioGRID9685412 |9852070 
|10075662 
TRAF5TNFRSF14Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID9153189 |9162022 
TRAF6MTHFD1Affinity Capture-MSBioGRID17353931 
TRAF6EPPK1Affinity Capture-MSBioGRID17353931 
TRAF6UBBTRAF6 interacts with Ub. This interaction was modeled on a demonstrated interaction between TRAF6 from mouse and Ub from an unspecified source.BIND15125833 
TRAF6IRF7IRF7 intereacts with TRAF6. This interaction was modeled on a demonstrated interaction between mouse IRF7 and human TRAF6.BIND15361868 
TRAF6IRAK2IRAK-2 interacts with TRAF6.BIND10383454 
-HPRD,BioGRID9374458 
TRAF6IRAK3IRAK-M interacts with TRAF6.BIND10383454 
-HPRD,BioGRID10383454 
TRAF6MAP3K7IP3TAB3 interacts with TRAF6.BIND15327770 
-HPRD,BioGRID14633987 
TRAF6MALT1TRAF6 interacts with MALT1. This interaction was modeled on a demonstrated interaction between TRAF6 from mouse and MALT1 from human.BIND15125833 
TRAF6IRAK3IRAK-M interacts with TRAF6.BIND10383454 
-HPRD,BioGRID10383454 
TRAF6TMEM189-UBE2V1-HPRD,BioGRID11057907 
TRAF6TICAM2-HPRD12721283 
TIRP interacts with TRAF6. This interaction was modeled on a demonstrated interaction between human TIRP and TRAF6 from an unspecified species.BIND12721283 
TRAF6IRAK1TRAF6 interacts with IRAK1. This interaction was modeled on a demonstrated interaction between TRAF6 and IRAK1, both from unspecified species.BIND15894263 
-HPRD,BioGRID8837778 
TRAF6PSMC2Affinity Capture-MSBioGRID14743216 
TRAF6ECSIT-HPRD,BioGRID10465784 
TRAF6MAP3K7-HPRD,BioGRID10094049 
TRAF6PSMD8-HPRD14743216 
TRAF6KCNQ1Affinity Capture-MSBioGRID14743216 
TRAF6ZFAND5Affinity Capture-WesternBioGRID14754897 
ZNF216 interacts with TRAF6. This interaction was modeled on a demonstrated interaction between human ZNF216 and TRAF6 from an unspecified species.BIND14754897 
TRAF6TICAM1TRIF interacts with TRAF6.BIND14530355 
An unspecified isoform of TRIF interacts with TRAF6. This interaction was modeled on a demonstrated interaction between TRIF from an unspecified species and TRAF from an unspecified species.BIND15474016 
TRAF6TNFRSF11AAffinity Capture-Western; Reconstituted ComplexBioGRID9685412 |9852070 
|10025951 |10075662 
|11809792 
-HPRD9685412 |10025951 
|10075662 |10635328 
TRAF6MCM7Affinity Capture-MSBioGRID17353931 
TRAF6NASPAffinity Capture-MSBioGRID17353931 
TRAF6IARSAffinity Capture-MSBioGRID17353931 
TRAF6PSMB5Affinity Capture-MSBioGRID14743216 
TRAF6MAP3K7IP3TAB3 interacts with TRAF6.BIND15327770 
-HPRD,BioGRID14633987 
TRAF6TNFRSF13B-HPRD,BioGRID10880535 
TRAF6TAX1BP1-HPRD,BioGRID10920205 
TRAF6CD40Reconstituted ComplexBioGRID9384571 |9990007 
-HPRD10075662 |10411888 
TRAF6CD40Reconstituted ComplexBioGRID9384571 |9990007 
-HPRD10075662 |10411888 
TRAF6EIF4E2Affinity Capture-MSBioGRID17353931 
TRAF6PELI3-HPRD12874243 
TRAF6TICAM2-HPRD12721283 
TIRP interacts with TRAF6. This interaction was modeled on a demonstrated interaction between human TIRP and TRAF6 from an unspecified species.BIND12721283 
TRAF6TRIM37-HPRD,BioGRID11279055 
TRAF6TIFA-HPRD,BioGRID12566447 
TRAF6TTRAP-HPRD,BioGRID10764746 
TRAF6PSMD3-HPRD,BioGRID14743216 
TRAF6IRAK4-HPRD,BioGRID11960013 
TRAF6MAP3K14-HPRD,BioGRID11278268 
NIK interacts with TRAF6. This interaction was modeled on a demonstrated interaction between human NIK and TRAF6 from an unspecified species.BIND9275204 
TRAF6OTUD7B-HPRD,BioGRID11463333 
-HPRD9928991 
TRAF6MAP3K5-HPRD,BioGRID10523862 
TRAF6ATP2A2-HPRD14743216 
TRAF6PSMD7Affinity Capture-MSBioGRID14743216 
TRAF6ZRANB1-HPRD,BioGRID11463333 
TRAF6EDA2R-HPRD,BioGRID12060722 
TRAF6PSMC1Affinity Capture-MSBioGRID14743216 
TRAF6VDAC1Affinity Capture-MSBioGRID17353931 
TRAF6PSMD4-HPRD14743216 
TRAF6ZNF675-HPRD,BioGRID11751921 
TRAF6XIAP-HPRD,BioGRID12048196 
TRAF6NGFR-HPRD,BioGRID10514511 
TRAF6ZFAND5Affinity Capture-WesternBioGRID14754897 
ZNF216 interacts with TRAF6. This interaction was modeled on a demonstrated interaction between human ZNF216 and TRAF6 from an unspecified species.BIND14754897 
TRAF6OTUD7B-HPRD,BioGRID11463333 
-HPRD9928991 
TRAF6SIGIRR-HPRD,BioGRID12925853 
TRAF6SPOP-HPRD,BioGRID11279055 
TRAF6TNFRSF19-HPRD,BioGRID12060722 
TRAF6TICAM1TRIF interacts with TRAF6.BIND14530355 
An unspecified isoform of TRIF interacts with TRAF6. This interaction was modeled on a demonstrated interaction between TRIF from an unspecified species and TRAF from an unspecified species.BIND15474016 
TRAF6TNFAIP3-HPRD,BioGRID9928991 
TRAF6PFASAffinity Capture-MSBioGRID17353931 
TRAF6TUBB2B-HPRD14743216 
TRAF6IRAK1TRAF6 interacts with IRAK1. This interaction was modeled on a demonstrated interaction between TRAF6 and IRAK1, both from unspecified species.BIND15894263 
-HPRD,BioGRID8837778 
TRAF6TJP2Affinity Capture-MSBioGRID17353931 
TRAF6TNFRSF11AAffinity Capture-Western; Reconstituted ComplexBioGRID9685412 |9852070 
|10025951 |10075662 
|11809792 
-HPRD9685412 |10025951 
|10075662 |10635328 
TRAF6HSPA8-HPRD14743216 
TRAF6VCPAffinity Capture-MSBioGRID17353931 
TRAF6CTPSAffinity Capture-MSBioGRID17353931 
TRAF6RIPK2-HPRD,BioGRID9642260 
TRAF6STRADB-HPRD,BioGRID12048196 
TRAF6MAP3K14-HPRD,BioGRID11278268 
NIK interacts with TRAF6. This interaction was modeled on a demonstrated interaction between human NIK and TRAF6 from an unspecified species.BIND9275204 
TRAF6TARSAffinity Capture-MSBioGRID17353931 
TRAF6PRKCZ-HPRD,BioGRID10747026 
TRAF6SQSTM1-HPRD,BioGRID10747026 |11244088 
TRAF6PSMD12-HPRD,BioGRID14743216 
TRAF6MAP3K7IP2-HPRD,BioGRID10882101 
TRAF6PSMD1-HPRD,BioGRID14743216 
TRAF6VARSAffinity Capture-MSBioGRID17353931 
TRAF6GANABAffinity Capture-MSBioGRID17353931 
TRAF6PSMA4-HPRD14743216 
TRAF6IL17RB-HPRD,BioGRID10748240 
TRAF6TUBA3C-HPRD14743216 
TRAF6SRC-HPRD,BioGRID10635328 
TRAF6RNF126-HPRD14743216 
TRAF6PSMC3Affinity Capture-MSBioGRID14743216 
TRAF6PSMD13Affinity Capture-MSBioGRID14743216 
TRAF6TNFSF11-HPRD10635328 
TRAF6PAICSAffinity Capture-MSBioGRID17353931 
TRAF6ASXL2Affinity Capture-MSBioGRID17353931 
TRAF6MAP3K7IP1-HPRD,BioGRID10094049 
TRAF6IRAK2IRAK-2 interacts with TRAF6.BIND10383454 
-HPRD,BioGRID9374458 
TRAF6MAST2-HPRD,BioGRID15308666 
TRAF6SYK-HPRD,BioGRID11418661 
TRAF6DDX3XAffinity Capture-MSBioGRID17353931 
TRAF6NTSR1-HPRD10514511 
TRAF4TRIM37-HPRD,BioGRID11279055 
TRAF4UBE2ITRAF4 interacts with UBC9.BIND12023963 
TRAF4BCKDKTRAF4 interacts with BCKDK.BIND12023963 
TRAF4RPS6KB1-HPRD,BioGRID12801526 
TRAF4TGFB1I1TRAF4 interacts with Hic-5.BIND12023963 
TRAF4NGFR-HPRD,BioGRID10514511 
TRAF4CCHCR1TRAF4 interacts with HCR.BIND12023963 
TRAF4TBC1D8TRAF4 interacts with VRP.BIND12023963 
TRAF4MAGED1TRAF4 interacts with NRAGE.BIND12023963 
TRAF4PXDNTRAF4 interacts with MAGE.BIND12023963 
TRAF4ME3TRAF4 interacts with NADP-ME.BIND12023963 
TRAF4LTBR-HPRD,BioGRID9626059 
TRAF4PLSCR1TRAF4 interacts with PLSCR1.BIND12023963 
TRAF4TARBP2TRAF4 interacts with TARBP2.BIND12023963 
TRAF4SIGLEC7-HPRD10514511 
TRAF4NCF1CTRAF4 interacts with p47phox.BIND12023963 
-HPRD12023963 
TRAF4SORBS2TRAF4 interacts with ArgBP2.BIND12023963 
TRAF4ACTN1TRAF4 interacts with alpha-actinin.BIND12023963 
TRAF4NCF1Affinity Capture-WesternBioGRID12023963 
TRAF4NCF1CTRAF4 interacts with p47phox.BIND12023963 
-HPRD12023963 
RNPS1GEMIN4Affinity Capture-MSBioGRID17353931 
RNPS1CDC2L2-HPRD,BioGRID9580558 
RNPS1RBM8AReconstituted ComplexBioGRID11707413 
RNPS1RANBP9Affinity Capture-MSBioGRID17353931 
RNPS1SF3B1Affinity Capture-MSBioGRID17353931 
RNPS1CSNK2A2Affinity Capture-MSBioGRID17353931 
RNPS1SRRM2Affinity Capture-MSBioGRID17353931 
RNPS1CSNK2BAffinity Capture-MSBioGRID17353931 
RNPS1SNRNP200Affinity Capture-MSBioGRID17353931 
RNPS1CDC2L1Affinity Capture-MSBioGRID17353931 
RNPS1PRPF3Affinity Capture-MSBioGRID17353931 
RNPS1RBM25Affinity Capture-MSBioGRID17353931 
RNPS1DDX20Affinity Capture-MSBioGRID17353931 
RNPS1NUDT21Affinity Capture-MSBioGRID17353931 
RNPS1AP2B1Affinity Capture-MSBioGRID17353931 
RNPS1DDX41Affinity Capture-MSBioGRID17353931 
RNPS1SFRS11RNPS1 interacts with p54.BIND14729963 
RNPS1PSME3Affinity Capture-MSBioGRID17353931 
RNPS1SFRS7Affinity Capture-MSBioGRID17353931 
RNPS1SRPK1Affinity Capture-MSBioGRID17353931 
RNPS1U2AF2Affinity Capture-MSBioGRID17353931 
RNPS1PRPF4BAffinity Capture-MSBioGRID17353931 
RNPS1LUC7L2Affinity Capture-MSBioGRID17353931 
RNPS1NKTRRNPS1 interacts with NKTR.BIND14729963 
RNPS1SIP1Affinity Capture-MSBioGRID17353931 
RNPS1PRPF40AAffinity Capture-MSBioGRID17353931 
RNPS1WDR33Affinity Capture-MSBioGRID17353931 
RNPS1DVL2Two-hybridBioGRID16189514 
RNPS1RARSAffinity Capture-MSBioGRID17353931 
RNPS1SFRS6Two-hybridBioGRID16189514 
RNPS1CSNK2A1Affinity Capture-MSBioGRID17353931 
RNPS1THRAP3Affinity Capture-MSBioGRID17353931 
RNPS1DDX23Affinity Capture-MSBioGRID17353931 
RNPS1SRRM1-HPRD,BioGRID12093754 
RNPS1SFRS1Affinity Capture-MSBioGRID17353931 
RNPS1MKLN1Affinity Capture-MSBioGRID17353931 
RNPS1DHX38Affinity Capture-MSBioGRID17353931 
RNPS1C14orf102Affinity Capture-MSBioGRID17353931 
RNPS1CROPAffinity Capture-MSBioGRID17353931 
RNPS1STRAPAffinity Capture-MSBioGRID17353931 
RNPS1SFRS2Affinity Capture-MSBioGRID17353931 
RNPS1ZFRRNPS1 interacts with Zfr.BIND14729963 
RNPS1CPSF6Affinity Capture-MSBioGRID17353931 
RNPS1SFRS8Affinity Capture-MSBioGRID17353931 
RNPS1LUC7LAffinity Capture-MSBioGRID17353931 
RNPS1SFRS10RNPS1 interacts with hTra2-beta.BIND14729963 
Affinity Capture-MSBioGRID17353931 
RNPS1TAF2RNPS1 interacts with CIF150.BIND14729963 
RNPS1SF3B3Affinity Capture-MSBioGRID17353931 
RNPS1SFRS10RNPS1 interacts with hTra2-beta.BIND14729963 
Affinity Capture-MSBioGRID17353931 
RNPS1FIP1L1RNPS1 interacts with DKFZp586K0717.BIND14729963 
RNPS1SNRNP70Affinity Capture-MSBioGRID17353931 
RNPS1SNRPAAffinity Capture-MSBioGRID17353931 
RNPS1SRPK2Affinity Capture-MSBioGRID17353931 
RNPS1PRPF6Affinity Capture-MSBioGRID17353931 
RNPS1PNN-HPRD,BioGRID14517304 
RNPS1PRPF8Affinity Capture-MSBioGRID17353931 
RNPS1SART3-HPRD,BioGRID11477570 
RNPS1PUF60Affinity Capture-MSBioGRID17353931 
RNPS1SKIV2L2Affinity Capture-MSBioGRID17353931 
RNPS1EFTUD2Affinity Capture-MSBioGRID17353931 
RNPS1CPSF2Affinity Capture-MSBioGRID17353931 
RNPS1C19orf29Affinity Capture-MSBioGRID17353931 
RNPS1KHKAffinity Capture-MSBioGRID17353931 
RNPS1C20orf11Affinity Capture-MSBioGRID17353931 
RNPS1ARS2Affinity Capture-MSBioGRID17353931 
RNPS1SFRS12Affinity Capture-MSBioGRID17353931 
TP53RFWD2The ubiquitin ligase COP1 interacts with p53 to cause p53 degradation.BIND15103385 
TP53POLA1-HPRD,BioGRID11917009 
TP53BCL6BCL6 interacts with the p53 promoter region.BIND15577913 
TP53PPP1R13LiASPP interacts with p53BIND15558054 
-HPRD,BioGRID12524540 
TP53PLAGL1-HPRD,BioGRID11360197 
TP53ARID3A-HPRD12136662 
TP53RPA1Affinity Capture-Western; Reconstituted ComplexBioGRID11751427 |15489903 
TP53TAF1C-HPRD,BioGRID10913176 
TP53TXNp53 interacts with Trx.BIND15824742 
TP53BAXp53 interacts with Bax.BIND15607964 
p53 interacts with bax promoter.BIND16009130 
p53 interacts with the Bax promoter.BIND15710329 
TP53XRCC6TP53 (p53) interacts with XRCC6 (Ku70).BIND15782130 
TP53EP300p300 interacts with p53BIND15558054 
p300 interacts with p53. This interaction was modeled on a demonstrated interaction between p300 from an unspecified species and human p53.BIND15186775 
p300 interacts with and acetylates p53. This interaction was modeled on a demonstrated interaction between p300 from an unspecified species and human p53.BIND15933712 
-HPRD,BioGRID10942770 
TP53SP1p53 interacts with Sp1.BIND15574328 
p53 interacts with Sp1.BIND9492043 
TP53 (p53) interacts with Sp1.BIND9685344 
TP53 (p53) interacts with SP1.BIND15674334 
TP53TFAP2Cp53 interacts with AP2gamma. This interaction was modelled on a demonstrated interaction between p53 from human and AP2gamma from an unspecified species.BIND12226108 
Reconstituted ComplexBioGRID12226108 
TP53CCNA2-HPRD,BioGRID10884347 
TP53TFAP2Cp53 interacts with AP2gamma. This interaction was modelled on a demonstrated interaction between p53 from human and AP2gamma from an unspecified species.BIND12226108 
Reconstituted ComplexBioGRID12226108 
TP53PRMT1-HPRD,BioGRID15186775 
PRMT1 interacts with p53. This interaction was modeled on a demonstrated interaction between rat PRMT1 and human p53.BIND15186775 
TP53NPTwo-hybridBioGRID16169070 
TP53MPHOSPH6Two-hybridBioGRID16169070 
TP53IFI16-HPRD,BioGRID11146555 
TP53TDGTwo-hybridBioGRID10961991 
TP53CREBBP-HPRD,BioGRID10848610 |11782467 
p53 interacts with CBP. This interaction was modeled on a demonstrated interaction between human p53 and CBP from an unspecified species.BIND10823891 
TP53TEP1-HPRD,BioGRID10597287 
TP53SAT1Two-hybridBioGRID16169070 
TP53ABL1-HPRD,BioGRID10629029 |10713716 
TP53YWHAZ-HPRD,BioGRID9620776 
TP53CABLES2-HPRD,BioGRID14637168 
TP53PIAS1Biochemical Activity; Reconstituted Complex; Two-hybridBioGRID10380882 |11583632 
PIAS1 interacts with p53. This interaction was modeled on a demonstrated interaction between human PIAS1 and p53 from an unspecified species.BIND15133049 
-HPRD11583632 |11788578 
|11867732 |15133049 
TP53HUWE1ARF-BP1 interacts with and ubiquitinates p53.BIND15989956 
TP53RFC1Affinity Capture-WesternBioGRID12509469 
TP53NTHL1NTH1 interacts with p53.BIND15358233 
TP53TFDP1-HPRD,BioGRID8816502 
TP53BCL2L1Bcl-xl interacts with p53.BIND14963330 
-HPRD12667443 
TP53NDN-HPRD,BioGRID10347180 
TP53CARM1Reconstituted ComplexBioGRID15186775 
CARM1 interacts with p53. This interaction was modeled on a demonstrated interaction between mouse CARM1 and human p53.BIND15186775 
TP53SFNAffinity Capture-WesternBioGRID11896572 
p53 interacts with the SFN (14-3-3-sigma) promoter.BIND15574328 
p53 interacts with 14-3-3-sigma promoter.BIND16009130 
TP53FXYD6Two-hybridBioGRID16169070 
TP53XRCC1Affinity Capture-WesternBioGRID15044383 
TP53BRCC3Affinity Capture-MS; Affinity Capture-Western; Co-purificationBioGRID14636569 
TP53MUC1MUC1 C-ter interacts with p53.BIND15710329 
TP53PRKRA-HPRD,BioGRID9010216 
TP53HIPK1-HPRD,BioGRID12702766 
TP53SMARCA4Affinity Capture-Western; Co-fractionation; Reconstituted ComplexBioGRID11950834 
TP53HNF4A-HPRD,BioGRID11818510 
TP53CDC2-HPRD,BioGRID11327730 
TP53NR3C1-HPRD,BioGRID11080152 
p53 interacts with GR. This interaction was modelled on a demonstrated interaction between p53 from an unspecified species and GR from an unspecified species.BIND9215863 
TP53S100A8Two-hybridBioGRID16169070 
TP53WRNWRN interacts with p53.BIND12080066 
-HPRD,BioGRID11427532 |12080066 
TP53SP1p53 interacts with Sp1.BIND15574328 
p53 interacts with Sp1.BIND9492043 
TP53 (p53) interacts with Sp1.BIND9685344 
TP53 (p53) interacts with SP1.BIND15674334 
TP53TADA3L-HPRD,BioGRID11707411 
TP53CCNHAffinity Capture-Western; Far WesternBioGRID9840937 
TP53PARC-HPRD,BioGRID12526791 
Parc interacts with p53BIND15558054 
TP53ZNF24Two-hybridBioGRID16169070 
TP53TNFRSF10CTP53 (p53) interacts with TNFRSF10C (TRAIL-R3) gene.BIND14623878 
TP53TFAP2Ap53 interacts with AP2alpha.BIND12226108 
-HPRD,BioGRID12226108 
TP53CDC42Two-hybridBioGRID16169070 
TP53CDKN2AAffinity Capture-WesternBioGRID9529249 |12446718 
|14612427 
TP53EIF2S2Two-hybridBioGRID16169070 
TP53STK4-HPRD12384512 |12942774 
TP53HMGB1p53 interacts with HMG-1.BIND9472015 
Affinity Capture-Western; Reconstituted ComplexBioGRID11106654 |11748221 
-HPRD9472015 
TP53ATM-HPRD,BioGRID9843217 
ATM phosphorylates p53 at serine 15.BIND15064416 
An unspecified isoform of ATM interacts with and phosphorylates p53. This interaction was modeled on a demonstrated interaction between human ATM and p53 from an unspecified species.BIND15916964 
ATM phosphorylates p53 at Ser15.BIND15175154 
ATM phosphorylates p53 at serine 15.BIND15790808 
TP53BAK1Mitochondrial p53-P72 interacts with Bak.BIND15077116 
Mitochondrial p53-R72 interacts with Bak.BIND15077116 
Affinity Capture-MS; Affinity Capture-Western; Reconstituted ComplexBioGRID15077116 
TP53EP300p300 interacts with p53BIND15558054 
p300 interacts with p53. This interaction was modeled on a demonstrated interaction between p300 from an unspecified species and human p53.BIND15186775 
p300 interacts with and acetylates p53. This interaction was modeled on a demonstrated interaction between p300 from an unspecified species and human p53.BIND15933712 
-HPRD,BioGRID10942770 
TP53MED1-HPRD,BioGRID9444950 |11118038 
TP53AURKAp53 interacts with STK15.BIND12198151 
-HPRD,BioGRID12198151 
TP53CCL18Two-hybridBioGRID16169070 
TP53CDK7Affinity Capture-Western; Biochemical ActivityBioGRID9372954 |9840937 
TP53MAPK10-HPRD,BioGRID9393873 
TP53GNL3-HPRD,BioGRID12464630 
TP53BLMBLM interacts with p53.BIND12080066 
BLM interacts with p53. This interaction was modeled on a demonstrated interaction between BLM and p53 both from African green monkey.BIND15806145 
-HPRD,BioGRID11781842 
p53 interacts with BLM.BIND11781842 
TP53UBE2I-HPRD,BioGRID8921390 
p53 interacts with Ubc9. This interaction was modelled on a demonstrated interaction between p53 from human and Ubc9 from an unspecified species.BIND10788439 
UBE2I interacts with TP53. This interaction was modelled on a demonstrated interaction between D. melanogaster Lwr (DmUbc9) and p53 from an unspecified species.BIND9514881 
TP53EFEMP2-HPRD,BioGRID10380882 
TP53HMGB1p53 interacts with HMG-1.BIND9472015 
Affinity Capture-Western; Reconstituted ComplexBioGRID11106654 |11748221 
-HPRD9472015 
TP53PCDHA4Two-hybridBioGRID16169070 
TP53TOPORSTopors interacts with p53. This interaction was modelled on a demonstrated interaction between human Topors and mouse p53.BIND11842245 
Two-hybridBioGRID11842245 
-HPRD10415337 
TP53MNAT1-HPRD,BioGRID9372954 
TP53SERPINB9Two-hybridBioGRID16169070 
TP53ATM-HPRD,BioGRID9843217 
ATM phosphorylates p53 at serine 15.BIND15064416 
An unspecified isoform of ATM interacts with and phosphorylates p53. This interaction was modeled on a demonstrated interaction between human ATM and p53 from an unspecified species.BIND15916964 
ATM phosphorylates p53 at Ser15.BIND15175154 
ATM phosphorylates p53 at serine 15.BIND15790808 
TP53UBE2I-HPRD,BioGRID8921390 
p53 interacts with Ubc9. This interaction was modelled on a demonstrated interaction between p53 from human and Ubc9 from an unspecified species.BIND10788439 
UBE2I interacts with TP53. This interaction was modelled on a demonstrated interaction between D. melanogaster Lwr (DmUbc9) and p53 from an unspecified species.BIND9514881 
TP53LAMA4Two-hybridBioGRID16169070 
TP53FAM173ATwo-hybridBioGRID16169070 
TP53BRCA1BRCA1a interacts with p53.BIND9926942 
BRCA1 physically associates with p53 and stimulates its transcriptional activityBIND9582019 
-HPRD,BioGRID9482880 
TP53SMARCB1-HPRD,BioGRID11950834 
TP53DVL2Two-hybridBioGRID16189514 
TP53CCNG1-HPRD,BioGRID12556559 
TP53CDKN2CTwo-hybridBioGRID16169070 
TP53WT1-HPRD,BioGRID8389468 
TP53CDC14A-HPRD,BioGRID10644693 
TP53ATM-HPRD,BioGRID9843217 
ATM phosphorylates p53 at serine 15.BIND15064416 
An unspecified isoform of ATM interacts with and phosphorylates p53. This interaction was modeled on a demonstrated interaction between human ATM and p53 from an unspecified species.BIND15916964 
ATM phosphorylates p53 at Ser15.BIND15175154 
ATM phosphorylates p53 at serine 15.BIND15790808 
TP53UBE2A-HPRD,BioGRID12640129 
TP53TP53BP1Affinity Capture-Western; Co-crystal Structure; Co-localization; Reconstituted Complex; Two-hybridBioGRID8016121 |11877378 
|12110597 |12351827 
|14978302 |15364958 
|15611139 
-HPRD8016121 |12110597 
TP53UBE2I-HPRD,BioGRID8921390 
p53 interacts with Ubc9. This interaction was modelled on a demonstrated interaction between p53 from human and Ubc9 from an unspecified species.BIND10788439 
UBE2I interacts with TP53. This interaction was modelled on a demonstrated interaction between D. melanogaster Lwr (DmUbc9) and p53 from an unspecified species.BIND9514881 
TP53ATM-HPRD,BioGRID9843217 
ATM phosphorylates p53 at serine 15.BIND15064416 
An unspecified isoform of ATM interacts with and phosphorylates p53. This interaction was modeled on a demonstrated interaction between human ATM and p53 from an unspecified species.BIND15916964 
ATM phosphorylates p53 at Ser15.BIND15175154 
ATM phosphorylates p53 at serine 15.BIND15790808 
TP53APTXAffinity Capture-Western; Reconstituted ComplexBioGRID15044383 
TP53TOP1-HPRD,BioGRID10468612 
TP53MDC1-HPRD,BioGRID14519663 
TP53GSK3Bp53 interacts with GSK3-beta.BIND12048243 
-HPRD,BioGRID12048243 
TP53STK11-HPRD,BioGRID11430832 
TP53ANKRD2-HPRD,BioGRID15136035 
TP53COX17Two-hybridBioGRID16169070 
TP53HIF1AAffinity Capture-Western; Reconstituted ComplexBioGRID9537326 |10640274 
|12124396 |12606552 
-HPRD9537326|12124396 
p53 interacts with HIF-1 alpha.BIND15629713 
HIF-1alpha interacts with p53BIND11593383 
TP53SMARCC1Co-fractionationBioGRID11950834 
TP53SUMO1Two-hybridBioGRID10961991 
p53 interacts with SUMO-1. This interaction was modelled on a demonstrated interaction between p53 from human and SUMO-1 from an unspecified species.BIND10788439 
TP53S100BAffinity Capture-WesternBioGRID15178678 
-HPRD10876243 |11527429 
TP53CREBBP-HPRD,BioGRID10848610 |11782467 
p53 interacts with CBP. This interaction was modeled on a demonstrated interaction between human p53 and CBP from an unspecified species.BIND10823891 
TP53PIN1-HPRD,BioGRID12388558 |12397362 
TP53RECQL4TP53 (p53) interacts with the RECQL4 (RECQ4) promoter.BIND15674334 
TP53SIN3Ap53 interacts with mSin3A. This interaction was modeled on a demonstrated interaction between human p53 and mSin3A from an unspecified species.BIND10823891 
TP53TK1Two-hybridBioGRID16169070 
TP53ERCC2-HPRD,BioGRID7663514 
TP53S100BAffinity Capture-WesternBioGRID15178678 
-HPRD10876243 |11527429 
TP53BCRTwo-hybridBioGRID16169070 
TP53RPL11Affinity Capture-WesternBioGRID14612427 
TP53BCL2-HPRD12667443 
TP53ELL-HPRD,BioGRID10358050 
TP53ATM-HPRD,BioGRID9843217 
ATM phosphorylates p53 at serine 15.BIND15064416 
An unspecified isoform of ATM interacts with and phosphorylates p53. This interaction was modeled on a demonstrated interaction between human ATM and p53 from an unspecified species.BIND15916964 
ATM phosphorylates p53 at Ser15.BIND15175154 
ATM phosphorylates p53 at serine 15.BIND15790808 
TP53BRCA1BRCA1a interacts with p53.BIND9926942 
BRCA1 physically associates with p53 and stimulates its transcriptional activityBIND9582019 
-HPRD,BioGRID9482880 
TP53SNRPNTwo-hybridBioGRID16169070 
TP53DHCR24Seladin-1 interacts with p53.BIND15577914 
TP53SUMO1Two-hybridBioGRID10961991 
p53 interacts with SUMO-1. This interaction was modelled on a demonstrated interaction between p53 from human and SUMO-1 from an unspecified species.BIND10788439 
TP53ING5-HPRD,BioGRID12750254 
p53 interacts with p28ING5.BIND12750254 
TP53RCHY1-HPRD,BioGRID12654245 
TP53PRKRIRReconstituted ComplexBioGRID12384512 
TP53NR3C1-HPRD,BioGRID11080152 
p53 interacts with GR. This interaction was modelled on a demonstrated interaction between p53 from an unspecified species and GR from an unspecified species.BIND9215863 
TP53TP53BP1Affinity Capture-Western; Co-crystal Structure; Co-localization; Reconstituted Complex; Two-hybridBioGRID8016121 |11877378 
|12110597 |12351827 
|14978302 |15364958 
|15611139 
-HPRD8016121 |12110597 
TP53ING1-HPRD,BioGRID9440695 |12208736 
p53 interacts with ING1b. This interaction was modelled on a demonstrated interaction between p53 from an unspecified species and human ING1b.BIND12208736 
TP53CHEK1-HPRD,BioGRID11896572 
TP53ERCC3p53 interacts with ERCC3. This interaction was modeled on a demonstrated interaction between human p53 and ERCC3 from an unspecified species.BIND12379483 
-HPRD,BioGRID7663514 
TP53GPS2-HPRD,BioGRID11486030 
p53 interacts with AMF1BIND11486030 
TP53CDKN1Ap53 interacts with p21 promoter.BIND16009130 
TP53 (p53) interacts with the CDKN1A (p21) promoter.BIND15674334 
p53 interacts with the p21 promoter.BIND15660129 
Affinity Capture-WesternBioGRID11896572 
p53 interacts with p21 promoter.BIND15989967 
p53 interacts with the p21 promoter.BIND15710329 
TP53YBX1-HPRD11175333 |11973333 
in vitro; in vivo; Reconstituted ComplexBioGRID11175333 |15136035 
TP53TAF1B-HPRD,BioGRID10913176 
TP53CDKN1Ap53 interacts with p21 promoter.BIND16009130 
TP53 (p53) interacts with the CDKN1A (p21) promoter.BIND15674334 
p53 interacts with the p21 promoter.BIND15660129 
Affinity Capture-WesternBioGRID11896572 
p53 interacts with p21 promoter.BIND15989967 
p53 interacts with the p21 promoter.BIND15710329 
TP53SETD7-HPRD15525938 
TP53BRCA1BRCA1a interacts with p53.BIND9926942 
BRCA1 physically associates with p53 and stimulates its transcriptional activityBIND9582019 
-HPRD,BioGRID9482880 
TP53BLMBLM interacts with p53.BIND12080066 
BLM interacts with p53. This interaction was modeled on a demonstrated interaction between BLM and p53 both from African green monkey.BIND15806145 
-HPRD,BioGRID11781842 
p53 interacts with BLM.BIND11781842 
TP53SP1p53 interacts with Sp1.BIND15574328 
p53 interacts with Sp1.BIND9492043 
TP53 (p53) interacts with Sp1.BIND9685344 
TP53 (p53) interacts with SP1.BIND15674334 
TP53BRF1-HPRD,BioGRID8943363 
TP53HMGB2-HPRD11748232 
TP53CDKN1Ap53 interacts with p21 promoter.BIND16009130 
TP53 (p53) interacts with the CDKN1A (p21) promoter.BIND15674334 
p53 interacts with the p21 promoter.BIND15660129 
Affinity Capture-WesternBioGRID11896572 
p53 interacts with p21 promoter.BIND15989967 
p53 interacts with the p21 promoter.BIND15710329 
TP53FOXO3Foxo3a interacts with p53.BIND15604409 
TP53PTGS2-HPRD,BioGRID11687965 
COX-2 interacts with p53.BIND15608668 
TP53PRMT1-HPRD,BioGRID15186775 
PRMT1 interacts with p53. This interaction was modeled on a demonstrated interaction between rat PRMT1 and human p53.BIND15186775 
TP53PTTG1-HPRD,BioGRID12355087 
p53 interacts with securin.BIND12355087 
TP53BARD1Affinity Capture-MS; Affinity Capture-WesternBioGRID14636569 
TP53 (p53) interacts with BARD1.BIND15782130 
TP53SSTR3-HPRD8961277 
TP53CCDC106Two-hybridBioGRID16169070 
TP53HIPK2Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybridBioGRID11740489 |11925430 
HIPK2 does not interact directly with tumour suppressor protein p53 but enhances p53 activity and p53 expression or stabilityBIND11532197 
TP53BAK1Mitochondrial p53-P72 interacts with Bak.BIND15077116 
Mitochondrial p53-R72 interacts with Bak.BIND15077116 
Affinity Capture-MS; Affinity Capture-Western; Reconstituted ComplexBioGRID15077116 
TP53MED17-HPRD,BioGRID10198638 
TP53ATRATR interacts with TP53 (p53).BIND15775976 
Protein-peptide; Reconstituted ComplexBioGRID10608806 |15159397 
TP53APEX1p53 interacts with Ref-1.BIND15824742 
-HPRD,BioGRID9119221 
TP53PRKDC-HPRD10470151 
Biochemical Activity; Protein-peptideBioGRID9679063 |10608806 
|12756247 
TP53HIF1AAffinity Capture-Western; Reconstituted ComplexBioGRID9537326 |10640274 
|12124396 |12606552 
-HPRD9537326|12124396 
p53 interacts with HIF-1 alpha.BIND15629713 
HIF-1alpha interacts with p53BIND11593383 
TP53TNFRSF10Bp53 interacts with DR5.BIND15607964 
TP53TAF9-HPRD,BioGRID7761466 
-HPRD7761466 |7809597 
|11278372 
TP53WDR33Two-hybridBioGRID16169070 
TP53ATRATR interacts with TP53 (p53).BIND15775976 
Protein-peptide; Reconstituted ComplexBioGRID10608806 |15159397 
TP53MTA2Reconstituted ComplexBioGRID12920132 
PID interacts with p53.BIND11099047 
TP53PPP2CAp53 interacts with PPP2CA. This interaction is modeled on a demonstrated interaction between p53 from an unspecified source and human PP2AC.BIND12556559 
TP53PMLAffinity Capture-Western; Reconstituted ComplexBioGRID11025664 |11080164 
|12915590 
-HPRD11025664 |11080164 
|11704853 
TP53ARL3Two-hybridBioGRID16169070 
TP53ESR1-HPRD,BioGRID10766163 
P53 interacts with ER-alpha.BIND10766163 
TP53MAD2L1BPTwo-hybridBioGRID16169070 
TP53GTF2H1-HPRD,BioGRID7935417 
TP53TOP2B-HPRD,BioGRID10666337 
TP53ZHX1-HPRD15383276 
TP53DDX5p68 interacts with p53.BIND15660129 
TP53ING5-HPRD,BioGRID12750254 
p53 interacts with p28ING5.BIND12750254 
TP53EP300p300 interacts with p53BIND15558054 
p300 interacts with p53. This interaction was modeled on a demonstrated interaction between p300 from an unspecified species and human p53.BIND15186775 
p300 interacts with and acetylates p53. This interaction was modeled on a demonstrated interaction between p300 from an unspecified species and human p53.BIND15933712 
-HPRD,BioGRID10942770 
TP53HDAC1Affinity Capture-WesternBioGRID12426395 
TP53CDC14B-HPRD,BioGRID10644693 
TP53DLEU1Two-hybridBioGRID16169070 
TP53BANP-HPRD15701641 
TP53MAPK9-HPRD,BioGRID9393873 
TP53GSK3Bp53 interacts with GSK3-beta.BIND12048243 
-HPRD,BioGRID12048243 
TP53BTBD2Two-hybridBioGRID16169070 
TP53PTEN-HPRD,BioGRID12620407 
TP53TOP2A-HPRD,BioGRID10666337 
TP53HSPB1Two-hybridBioGRID16169070 
TP53ANXA3Two-hybridBioGRID16169070 
TP53EEF2-HPRD,BioGRID12891704 
TP53TAF1A-HPRD,BioGRID10913176 
TP53UBE3A-HPRD9143503 |9369221 
TP53PSMD11Two-hybridBioGRID16169070 
TP53YBX1-HPRD11175333 |11973333 
in vitro; in vivo; Reconstituted ComplexBioGRID11175333 |15136035 
TP53EPHA3Reconstituted ComplexBioGRID15355990 
TP53PLK3-HPRD,BioGRID11551930 
TP53HSPA8Hsc70 interacts with p53.BIND8940078 
Reconstituted ComplexBioGRID11297531 
p53 interacts with an unspecified isoform of Hsc70. This interaction was modeled on a demonstrated interaction between human p53 and bovine Hsc70.BIND9235949 
TP53RAB4ATwo-hybridBioGRID16169070 
TP53PPP4CReconstituted ComplexBioGRID9837938 
TP53CR2P53 interacts with CR2.BIND7753047 
-HPRD,BioGRID7753047 
TP53HSPA1A-HPRD7811761 
TP53BAXp53 interacts with Bax.BIND15607964 
p53 interacts with bax promoter.BIND16009130 
p53 interacts with the Bax promoter.BIND15710329 
TP53HMGB1p53 interacts with HMG-1.BIND9472015 
Affinity Capture-Western; Reconstituted ComplexBioGRID11106654 |11748221 
-HPRD9472015 
TP53MTA2Reconstituted ComplexBioGRID12920132 
PID interacts with p53.BIND11099047 
TP53NFKBIA-HPRD,BioGRID11799106 
TP53PMLAffinity Capture-Western; Reconstituted ComplexBioGRID11025664 |11080164 
|12915590 
-HPRD11025664 |11080164 
|11704853 
TP53ERCC6-HPRD,BioGRID10882116 
TP53TSG101-HPRD,BioGRID11172000 
TP53APEX1p53 interacts with Ref-1.BIND15824742 
-HPRD,BioGRID9119221 
TP53TP53I3p53 interacts with PIG3 promoter.BIND16009130 
TP53PPP1R13LiASPP interacts with p53BIND15558054 
-HPRD,BioGRID12524540 
TP53BAK1Mitochondrial p53-P72 interacts with Bak.BIND15077116 
Mitochondrial p53-R72 interacts with Bak.BIND15077116 
Affinity Capture-MS; Affinity Capture-Western; Reconstituted ComplexBioGRID15077116 
TP53HSPA9-HPRD,BioGRID11900485 
TP53SULT1E1Two-hybridBioGRID16169070 
TP53CSNK2B-HPRD10214938 
TP53ESR1-HPRD,BioGRID10766163 
P53 interacts with ER-alpha.BIND10766163 
TP53ERCC3p53 interacts with ERCC3. This interaction was modeled on a demonstrated interaction between human p53 and ERCC3 from an unspecified species.BIND12379483 
-HPRD,BioGRID7663514 
TP53CSNK1D-HPRD9349507 
TP53PIAS1Biochemical Activity; Reconstituted Complex; Two-hybridBioGRID10380882 |11583632 
PIAS1 interacts with p53. This interaction was modeled on a demonstrated interaction between human PIAS1 and p53 from an unspecified species.BIND15133049 
-HPRD11583632 |11788578 
|11867732 |15133049 
TP53NPM1-HPRD12080348 
TP53PHBAffinity Capture-Western; Co-localization; Reconstituted ComplexBioGRID14500729 
TP53ERHTwo-hybridBioGRID16169070 
TP53CDK9Phenotypic SuppressionBioGRID10656684 
TP53SMN1-HPRD,BioGRID11704667 
TP53SFNAffinity Capture-WesternBioGRID11896572 
p53 interacts with the SFN (14-3-3-sigma) promoter.BIND15574328 
p53 interacts with 14-3-3-sigma promoter.BIND16009130 
TP53PRKCA-HPRD9935181 
TP53ING1-HPRD,BioGRID9440695 |12208736 
p53 interacts with ING1b. This interaction was modelled on a demonstrated interaction between p53 from an unspecified species and human ING1b.BIND12208736 
TP53CARM1Reconstituted ComplexBioGRID15186775 
CARM1 interacts with p53. This interaction was modeled on a demonstrated interaction between mouse CARM1 and human p53.BIND15186775 
TP53AURKAp53 interacts with STK15.BIND12198151 
-HPRD,BioGRID12198151 
TP53HSPA8Hsc70 interacts with p53.BIND8940078 
Reconstituted ComplexBioGRID11297531 
p53 interacts with an unspecified isoform of Hsc70. This interaction was modeled on a demonstrated interaction between human p53 and bovine Hsc70.BIND9235949 
TP53MAGEB18Two-hybridBioGRID16189514 
TP53TAGAffinity Capture-WesternBioGRID14612521 
TP53MSX1MSX1 interacts with TP53 (p53). This interaction was modeled on a demonstrated interaction between MSX1 from an unspecified species, and human p53.BIND15705871 
TP53TP53BP2-HPRD,BioGRID8016121 |8668206 
|8875926 
TP53NCL-HPRD,BioGRID12138209 
TP53HSP90AA1-HPRD,BioGRID11507088 |12427754 
TP53CSNK1E-HPRD9349507 
TP53HSPA8Hsc70 interacts with p53.BIND8940078 
Reconstituted ComplexBioGRID11297531 
p53 interacts with an unspecified isoform of Hsc70. This interaction was modeled on a demonstrated interaction between human p53 and bovine Hsc70.BIND9235949 
TP53PTTG1-HPRD,BioGRID12355087 
p53 interacts with securin.BIND12355087 
TP53MTA1-HPRD,BioGRID12920132 
TP53CDKN1Ap53 interacts with p21 promoter.BIND16009130 
TP53 (p53) interacts with the CDKN1A (p21) promoter.BIND15674334 
p53 interacts with the p21 promoter.BIND15660129 
Affinity Capture-WesternBioGRID11896572 
p53 interacts with p21 promoter.BIND15989967 
p53 interacts with the p21 promoter.BIND15710329 
TP53S100A4-HPRD,BioGRID11278647 |11527429 
|12942774 |15116098 
TP53RRM2B-HPRD,BioGRID12615712 
TP53GPS2-HPRD,BioGRID11486030 
p53 interacts with AMF1BIND11486030 
TP53CDKN1Ap53 interacts with p21 promoter.BIND16009130 
TP53 (p53) interacts with the CDKN1A (p21) promoter.BIND15674334 
p53 interacts with the p21 promoter.BIND15660129 
Affinity Capture-WesternBioGRID11896572 
p53 interacts with p21 promoter.BIND15989967 
p53 interacts with the p21 promoter.BIND15710329 
TP53TAF1-HPRD7809597 
Affinity Capture-WesternBioGRID10359315 
TP53STX5Two-hybridBioGRID16169070 
TP53BCL2L1Bcl-xl interacts with p53.BIND14963330 
-HPRD12667443 
TP53TBP-HPRD,BioGRID1465435 
TP53UBE2K-HPRD10634809 
TP53MAPK3-HPRD,BioGRID10958792 
TP53HIF1AAffinity Capture-Western; Reconstituted ComplexBioGRID9537326 |10640274 
|12124396 |12606552 
-HPRD9537326|12124396 
p53 interacts with HIF-1 alpha.BIND15629713 
HIF-1alpha interacts with p53BIND11593383 
TP53CDC25C-HPRD10853038 
p53 interacts with the cdc25c promoter.BIND15574328 
TP53PPA1Two-hybridBioGRID16169070 
TP53ATF3-HPRD,BioGRID11792711 
An unspecified isoform of ATF3 interacts with p53.BIND15933712 
TP53SP1p53 interacts with Sp1.BIND15574328 
p53 interacts with Sp1.BIND9492043 
TP53 (p53) interacts with Sp1.BIND9685344 
TP53 (p53) interacts with SP1.BIND15674334 
TP53CABLES1-HPRD,BioGRID14637168 
-HPRD11706030 
TP53TFAP2Ap53 interacts with AP2alpha.BIND12226108 
-HPRD,BioGRID12226108 
TP53TOPORSTopors interacts with p53. This interaction was modelled on a demonstrated interaction between human Topors and mouse p53.BIND11842245 
Two-hybridBioGRID11842245 
-HPRD10415337 
TP53PARP1-HPRD,BioGRID9565608 
TP53WRNWRN interacts with p53.BIND12080066 
-HPRD,BioGRID11427532 |12080066 
TP53KPNB1-HPRD,BioGRID11297531 
TP53PAFAH1B3Two-hybridBioGRID16169070 
TP53TAF9-HPRD,BioGRID7761466 
-HPRD7761466 |7809597 
|11278372 
TP53CREB1Affinity Capture-Western; Reconstituted ComplexBioGRID10848610 
TP53PRKDC-HPRD10470151 
Biochemical Activity; Protein-peptideBioGRID9679063 |10608806 
|12756247 
TP53GSTM4Two-hybridBioGRID16169070 
TP53PIAS1Biochemical Activity; Reconstituted Complex; Two-hybridBioGRID10380882 |11583632 
PIAS1 interacts with p53. This interaction was modeled on a demonstrated interaction between human PIAS1 and p53 from an unspecified species.BIND15133049 
-HPRD11583632 |11788578 
|11867732 |15133049 
TP53MRE11AMre11 interacts with p53. This interaction was modeled on a demonstrated interaction between Mre11 and p53 both from African green monkey.BIND15806145 
TP53WWOX-HPRD,BioGRID11058590 
TP53TAF1-HPRD7809597 
Affinity Capture-WesternBioGRID10359315 
TP53ING4-HPRD,BioGRID12750254 
p53 interacts with p29ING4.BIND12750254 
TP53SFNAffinity Capture-WesternBioGRID11896572 
p53 interacts with the SFN (14-3-3-sigma) promoter.BIND15574328 
p53 interacts with 14-3-3-sigma promoter.BIND16009130 
TP53BARD1Affinity Capture-MS; Affinity Capture-WesternBioGRID14636569 
TP53 (p53) interacts with BARD1.BIND15782130 
TP53E4F1-HPRD,BioGRID10644996 |12446718|12446718 
TP53HTTp53 interacts with htt. This interaction was modeled on a demonstrated interaction between p53 from human and htt from an unspecified species.BIND10823891 
Htt interacts with TP53(p53).BIND15996546 
-HPRD,BioGRID10823891 
TP53BREAffinity Capture-MS; Affinity Capture-Western; Co-purificationBioGRID14636569 
TP53BNIP3Lp53 interacts with Bnip3L.BIND15607964 
TP53HTTp53 interacts with htt. This interaction was modeled on a demonstrated interaction between p53 from human and htt from an unspecified species.BIND10823891 
Htt interacts with TP53(p53).BIND15996546 
-HPRD,BioGRID10823891 
TP53ATF3-HPRD,BioGRID11792711 
An unspecified isoform of ATF3 interacts with p53.BIND15933712 
TP53CDK2Biochemical ActivityBioGRID10884347 
TP53CDKN1Ap53 interacts with p21 promoter.BIND16009130 
TP53 (p53) interacts with the CDKN1A (p21) promoter.BIND15674334 
p53 interacts with the p21 promoter.BIND15660129 
Affinity Capture-WesternBioGRID11896572 
p53 interacts with p21 promoter.BIND15989967 
p53 interacts with the p21 promoter.BIND15710329 
TP53SMG1hSMG-1 phosphorylates p53.BIND15175154 
TP53CEBPZ-HPRD,BioGRID12534345 
TP53EP300p300 interacts with p53BIND15558054 
p300 interacts with p53. This interaction was modeled on a demonstrated interaction between p300 from an unspecified species and human p53.BIND15186775 
p300 interacts with and acetylates p53. This interaction was modeled on a demonstrated interaction between p300 from an unspecified species and human p53.BIND15933712 
-HPRD,BioGRID10942770 
TP53PARC-HPRD,BioGRID12526791 
Parc interacts with p53BIND15558054 
TP53BAG1Phenotypic SuppressionBioGRID9582267 
TP53THRB-HPRD,BioGRID11258898 
TP53EIF2AK2-HPRD,BioGRID10348343 
TP53BAXp53 interacts with Bax.BIND15607964 
p53 interacts with bax promoter.BIND16009130 
p53 interacts with the Bax promoter.BIND15710329 
TP53BLMBLM interacts with p53.BIND12080066 
BLM interacts with p53. This interaction was modeled on a demonstrated interaction between BLM and p53 both from African green monkey.BIND15806145 
-HPRD,BioGRID11781842 
p53 interacts with BLM.BIND11781842 
TP53HIPK3Two-hybridBioGRID10961991 
TP53RAD51-HPRD,BioGRID8617246 |9380510 
TP53ZCCHC10Two-hybridBioGRID16169070 
TP53THAP8Two-hybridBioGRID16169070 
TP53CR2P53 interacts with CR2.BIND7753047 
-HPRD,BioGRID7753047 
TP53ING4-HPRD,BioGRID12750254 
p53 interacts with p29ING4.BIND12750254 
TP53YY1YY1 interacts with p53.BIND15210108 
TP53PTGS2-HPRD,BioGRID11687965 
COX-2 interacts with p53.BIND15608668 
TP53CHD3-HPRD,BioGRID10961991 
TP53BLMBLM interacts with p53.BIND12080066 
BLM interacts with p53. This interaction was modeled on a demonstrated interaction between BLM and p53 both from African green monkey.BIND15806145 
-HPRD,BioGRID11781842 
p53 interacts with BLM.BIND11781842 
TP53ARBiochemical Activity; Phenotypic SuppressionBioGRID11504717 
TP53SAE1-HPRD15327968 
TP53RRM2-HPRD,BioGRID12615712 
TP53MAPK1Affinity Capture-WesternBioGRID10958792 
TP53TOPORSTopors interacts with p53. This interaction was modelled on a demonstrated interaction between human Topors and mouse p53.BIND11842245 
Two-hybridBioGRID11842245 
-HPRD10415337 
TP53BRCA2-HPRD,BioGRID9811893 
TP53CCT5Two-hybridBioGRID16169070 
TP53ARIH2Two-hybridBioGRID16169070 
TP53CDC25C-HPRD10853038 
p53 interacts with the cdc25c promoter.BIND15574328 
TP53HIPK2Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybridBioGRID11740489 |11925430 
HIPK2 does not interact directly with tumour suppressor protein p53 but enhances p53 activity and p53 expression or stabilityBIND11532197 
TP53KAT2BBiochemical ActivityBioGRID12068014 
TP53ZNF148-HPRD,BioGRID11416144 
TP53CHUK-HPRD11805286 
TP53TP53INP1-HPRD,BioGRID11511362 |12851404 
TP53KIAA0087Two-hybridBioGRID16169070 
TP53MAPK8-HPRD,BioGRID9393873|9732264 
TP53SHISA5-HPRD12135983 
TP53CABLES1-HPRD,BioGRID14637168 
-HPRD11706030 
TP53HTTp53 interacts with htt. This interaction was modeled on a demonstrated interaction between p53 from human and htt from an unspecified species.BIND10823891 
Htt interacts with TP53(p53).BIND15996546 
-HPRD,BioGRID10823891 
TP53TP53RKReconstituted ComplexBioGRID12659830 
TP53HIF1AAffinity Capture-Western; Reconstituted ComplexBioGRID9537326 |10640274 
|12124396 |12606552 
-HPRD9537326|12124396 
p53 interacts with HIF-1 alpha.BIND15629713 
HIF-1alpha interacts with p53BIND11593383 
TP53EGR1-HPRD,BioGRID11251186 
MDM2AR-HPRD12145204 
MDM2SP1SP1 interacts with the MDM2 intronic promoter.BIND15550242 
MDM2AKT1HDM2 interacts with and is phosphorylated by Akt.BIND11960368 
MDM2RBL2p130 interacts with Mdm2.BIND15577944 
MDM2GTF2E1Reconstituted ComplexBioGRID9271120 
MDM2KAT5-HPRD,BioGRID11927554 
MDM2CCNG1-HPRD,BioGRID12556559 
MDM2PJA1-HPRD10722742 
MDM2PIAS1-HPRD12393906 
MDM2PSMD10An unspecified isoform of gankyrin interacts with Mdm2.BIND16023600 
MDM2MTBP-HPRD,BioGRID10906133 
MDM2TAF1-HPRD,BioGRID9388200 
MDM2DHCR24Seladin-1 interacts with an unspecified isoform of Mdm2.BIND15577914 
MDM2GTF2E2-HPRD9271120 
MDM2CDKN2A-HPRD9529248 |12085228|9529249 
p14ARF interacts with an unspecified isoform of Mdm2.BIND12582152 
Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID9529248 |9529249 
|12085228 |14612427 
Mdm2 interacts with p14ARF.BIND10822382 
p14 interacts with MDM2.BIND15355988 
MDM2 interacts with p14ARFBIND9653180 
MDM2RB1-HPRD,BioGRID7791904|10078201 |10721693 
Rb interacts with Mdm2.BIND15577944 
Rb interacts with MDM2.BIND15485814 
MDM2NUMB-HPRD,BioGRID12646252 
MDM2TP73-HPRD,BioGRID10207051 
MDM2TSG101-HPRD,BioGRID11172000 
MDM2UBE2AAffinity Capture-WesternBioGRID12640129 
MDM2RB1-HPRD,BioGRID7791904|10078201 |10721693 
Rb interacts with Mdm2.BIND15577944 
Rb interacts with MDM2.BIND15485814 
MDM2SUMO1-HPRD10892746 
MDM2CTBP2Affinity Capture-Western; Reconstituted ComplexBioGRID12867035 
MDM2HIF1AAffinity Capture-Western; Biochemical Activity; Reconstituted ComplexBioGRID10640274 |12606552 
-HPRD10640274|12606552 
MDM2ESR1Reconstituted ComplexBioGRID10766163 
MDM2EID1-HPRD,BioGRID11073989 
MDM2HDAC1-HPRD,BioGRID12426395 
MDM2ARRB2-HPRD,BioGRID12488444 |12538596 
-HPRD11588219 |12488444 
|12538596|12488444 |12538596 
MDM2PMLPML interacts with Mdm2.BIND15195100 
-HPRD,BioGRID12759344 |12915590 
|14507915 |15195100 
MDM2RPL11Affinity Capture-MS; Affinity Capture-WesternBioGRID14612427 
L11 interacts with Hdm2.BIND12842086 
MDM2KAT2B-HPRD,BioGRID12068014 
MDM2HIST3H3Mdm2 interacts with H3.BIND15546622 
MDM2ABL1-HPRD,BioGRID12110584 
MDM2HIST4H4Mdm2 interacts with H4.BIND15546622 
MDM2RPL5-HPRD,BioGRID7935455 |14612427 
MDM2ARRB2-HPRD,BioGRID12488444 |12538596 
-HPRD11588219 |12488444 
|12538596|12488444 |12538596 
MDM2CDKN2A-HPRD9529248 |12085228|9529249 
p14ARF interacts with an unspecified isoform of Mdm2.BIND12582152 
Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID9529248 |9529249 
|12085228 |14612427 
Mdm2 interacts with p14ARF.BIND10822382 
p14 interacts with MDM2.BIND15355988 
MDM2 interacts with p14ARFBIND9653180 
MDM2CDKN2A-HPRD9529248 |12085228|9529249 
p14ARF interacts with an unspecified isoform of Mdm2.BIND12582152 
Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID9529248 |9529249 
|12085228 |14612427 
Mdm2 interacts with p14ARF.BIND10822382 
p14 interacts with MDM2.BIND15355988 
MDM2 interacts with p14ARFBIND9653180 
MDM2CTBP1Affinity Capture-Western; Far WesternBioGRID12867035 
MDM2CDKN1AMdm2 interacts with the p21 promoter.BIND15546622 
MDM2PMLPML interacts with Mdm2.BIND15195100 
-HPRD,BioGRID12759344 |12915590 
|14507915 |15195100 
MDM2MAPKAPK2MDM2 (HDM2) interacts with MAPKAPK2 isoform 1 (MK2). This interaction was modeled on a demonstrated interaction between MDM2 from an unspecified species, and human MAPKAPK2.BIND15688025 
MDM2 (HDM2) interacts with MAPKAPK2 (MK2) isoform 2. This interaction was modeled on a demonstrated interaction between MDM2 from an unspecified species, and human MAPKAPK2.BIND15688025 
MDM2TBPReconstituted ComplexBioGRID9271120 |9388200 
MDM2MDC1Protein-peptideBioGRID14578343 
MDM2CDKN2A-HPRD9529248 |12085228|9529249 
p14ARF interacts with an unspecified isoform of Mdm2.BIND12582152 
Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID9529248 |9529249 
|12085228 |14612427 
Mdm2 interacts with p14ARF.BIND10822382 
p14 interacts with MDM2.BIND15355988 
MDM2 interacts with p14ARFBIND9653180 
MDM2CDKN2A-HPRD9529248 |12085228|9529249 
p14ARF interacts with an unspecified isoform of Mdm2.BIND12582152 
Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID9529248 |9529249 
|12085228 |14612427 
Mdm2 interacts with p14ARF.BIND10822382 
p14 interacts with MDM2.BIND15355988 
MDM2 interacts with p14ARFBIND9653180 
MDM2CDKN2A-HPRD9529248 |12085228|9529249 
p14ARF interacts with an unspecified isoform of Mdm2.BIND12582152 
Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID9529248 |9529249 
|12085228 |14612427 
Mdm2 interacts with p14ARF.BIND10822382 
p14 interacts with MDM2.BIND15355988 
MDM2 interacts with p14ARFBIND9653180 
MDM2YY1YY1 interacts with Hdm2.BIND15210108 
MDM2RB1-HPRD,BioGRID7791904|10078201 |10721693 
Rb interacts with Mdm2.BIND15577944 
Rb interacts with MDM2.BIND15485814 
MDM2EP300-HPRD,BioGRID9809062 
MDM2MAPKAPK2MDM2 (HDM2) interacts with MAPKAPK2 isoform 1 (MK2). This interaction was modeled on a demonstrated interaction between MDM2 from an unspecified species, and human MAPKAPK2.BIND15688025 
MDM2 (HDM2) interacts with MAPKAPK2 (MK2) isoform 2. This interaction was modeled on a demonstrated interaction between MDM2 from an unspecified species, and human MAPKAPK2.BIND15688025 
MDM2ARRB1Affinity Capture-WesternBioGRID12538596 
MDM2HIF1AAffinity Capture-Western; Biochemical Activity; Reconstituted ComplexBioGRID10640274 |12606552 
-HPRD10640274|12606552 
MDM2RPL11Affinity Capture-MS; Affinity Capture-WesternBioGRID14612427 
L11 interacts with Hdm2.BIND12842086 
TRAF2TNFRSF12A-HPRD,BioGRID11728344 
TRAF2CASP8AP2-HPRD,BioGRID11340079 
TRAF2TRADD-HPRD,BioGRID8565075 |8702708 
|10892748 
TRAF2 interacts with TRADD. This interaction was modeled on a demonstrated interaction between human TRAF2 and TRADD from an unspecified species.BIND8702708 
TRADD interacts with TRAF2. This interaction was modeled on a demonstrated interaction between TRADD and TRAF2, both from an unspecified species.BIND12796506 
TRAF2MAPK9-HPRD10490605 
TRAF2FATE1Two-hybridBioGRID16189514 
TRAF2IPO11Two-hybridBioGRID16189514 
TRAF2MAP4K2-HPRD,BioGRID9712898 
The carboxy-terminal TRAF domain of TRAF2 interacts with the carboxy-terminal domain of GCK.BIND9712898 
TRAF2RIPK2-HPRD,BioGRID9705938 
TRAF2APIP-HPRD14743216 
TRAF2CD40-HPRD,BioGRID10411888 
CD40 interacts with TRAF2.BIND10352240 
TRAF2RIPK1-HPRD,BioGRID8612133 |8702708 
TRAF2 ubiquitinates RIP.BIND15258597 
TRAF2 interacts with RIP.BIND8702708 
TRAF2CASP8Affinity Capture-WesternBioGRID12887920 
TRAF2FXR2Two-hybridBioGRID16189514 
TRAF2BCL10-HPRD,BioGRID10753917 
TRAF2FBF1Two-hybridBioGRID16189514 
TRAF2RIPK1-HPRD,BioGRID8612133 |8702708 
TRAF2 ubiquitinates RIP.BIND15258597 
TRAF2 interacts with RIP.BIND8702708 
TRAF2CD40-HPRD,BioGRID10411888 
CD40 interacts with TRAF2.BIND10352240 
TRAF2AASDHPPTTwo-hybridBioGRID16189514 
TRAF2TNFRSF11AAffinity Capture-Western; Reconstituted ComplexBioGRID9685412 |9852070 
|10025951 |10075662 
-HPRD9774460 |9852070 
|10025951 
TRAF2TNFRSF4-HPRD,BioGRID9418902 
TRAF2CAV1-HPRD,BioGRID11112773 |11805080 
TRAF2MAP4K5-HPRD,BioGRID10477597 
TRAF2CFLAR-HPRD,BioGRID9208847 
TRAF2TCEA2Two-hybridBioGRID16189514 
TRAF2APPL1Two-hybridBioGRID16189514 
TRAF2RIPK3-HPRD,BioGRID10339433 
TRAF2USP53Two-hybridBioGRID16189514 
TRAF2CALCOCO2Two-hybridBioGRID16189514 
TRAF2TNIK-HPRD,BioGRID10521462 
TRAF2TRADD-HPRD,BioGRID8565075 |8702708 
|10892748 
TRAF2 interacts with TRADD. This interaction was modeled on a demonstrated interaction between human TRAF2 and TRADD from an unspecified species.BIND8702708 
TRADD interacts with TRAF2. This interaction was modeled on a demonstrated interaction between TRADD and TRAF2, both from an unspecified species.BIND12796506 
TRAF2TNFRSF8-HPRD8943059 |8999898 
-HPRD,BioGRID8627180 |8943059 
|8999898 |9168896 
|9353251 |11971184|8943059 
|8999898 
TRAF2 interacts with CD30.BIND8662842 
TRAF2TTRAP-HPRD,BioGRID10764746 
TRAF2TRADD-HPRD,BioGRID8565075 |8702708 
|10892748 
TRAF2 interacts with TRADD. This interaction was modeled on a demonstrated interaction between human TRAF2 and TRADD from an unspecified species.BIND8702708 
TRADD interacts with TRAF2. This interaction was modeled on a demonstrated interaction between TRADD and TRAF2, both from an unspecified species.BIND12796506 
TRAF2TNFRSF14-HPRD,BioGRID9153189 |9162022 
TRAF2TNFSF4-HPRD9418902 
TRAF2TNFRSF11AAffinity Capture-Western; Reconstituted ComplexBioGRID9685412 |9852070 
|10025951 |10075662 
-HPRD9774460 |9852070 
|10025951 
TRAF2LZTS2Two-hybridBioGRID16189514 
TRAF2BIRC2c-IAP1 interacts with and ubiquitinates TRAF2.BIND11907583 
-HPRD8643514 |9384571 
|11907583 
Affinity Capture-Western; in vitro; Reconstituted Complex; Two-hybridBioGRID8643514 |8943045 
|9384571 |11907583 
|16189514 
TRAF2NGFR-HPRD,BioGRID10514511 
TRAF2TIFATwo-hybridBioGRID16189514 
-HPRD11798190 
TRAF2CCDC33Two-hybridBioGRID16189514 
TRAF2AFF4Two-hybridBioGRID16189514 
TRAF2SIAH2-HPRD,BioGRID12411493 
TRAF2FAM107ATwo-hybridBioGRID16189514 
TRAF2NECAP2Two-hybridBioGRID16189514 
TRAF2LTBR-HPRD12169272 
TRAF2 interacts with LTBR.BIND12571250 
Reconstituted ComplexBioGRID9162022 
TRAF2EDARADDAffinity Capture-WesternBioGRID11882293 
TRAF2BIRC2c-IAP1 interacts with and ubiquitinates TRAF2.BIND11907583 
-HPRD8643514 |9384571 
|11907583 
Affinity Capture-Western; in vitro; Reconstituted Complex; Two-hybridBioGRID8643514 |8943045 
|9384571 |11907583 
|16189514 
TRAF2BIRC3-HPRD8643514 |11907583 
in vitro; Reconstituted Complex; Two-hybridBioGRID8643514 |9384571 
|11907583 
c-IAP2 interacts with TRAF2.BIND11907583 
TRAF2CASP12Affinity Capture-WesternBioGRID11278723 
TRAF2RAD23ATwo-hybridBioGRID16189514 
TRAF2TCEB3BTwo-hybridBioGRID16189514 
TRAF2CHUK-HPRD,BioGRID11359906 
TRAF2TNFRSF1A-HPRD,BioGRID8565075 
TRAF2TAOK3-HPRD,BioGRID11278723 
TRAF2TNFRSF8-HPRD8943059 |8999898 
-HPRD,BioGRID8627180 |8943059 
|8999898 |9168896 
|9353251 |11971184|8943059 
|8999898 
TRAF2 interacts with CD30.BIND8662842 
TRAF2TNFSF9-HPRD,BioGRID9607925 
TRAF2QARSTwo-hybridBioGRID16189514 
TRAF2HSPA4-HPRD14743216 
TRAF2TNFSF14Affinity Capture-MS; Affinity Capture-WesternBioGRID12571250 
TRAF2TNFRSF1BTRAF2 interacts with TRAF1. This interaction was modeled on a demonstrated interaction between human TRAF2 and TNF-R2 from an unspecified species.BIND8702708 
-HPRD7639698 |8702708 
|9461607 |11907088 
Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID7639698 |8702708 
|8710854 |9162022 
|11907088 |14743216 
TRAF2NUDT18Two-hybridBioGRID16189514 
TRAF2MALT1TRAF2 interacts with MALT1.BIND15125833 
TRAF2C16orf48Two-hybridBioGRID16189514 
TRAF2HSPA8-HPRD14743216 
TRAF2HIVEP3-HPRD,BioGRID11804591 
TRAF2SPRY2Two-hybridBioGRID16189514 
TRAF2BIRC3-HPRD8643514 |11907583 
in vitro; Reconstituted Complex; Two-hybridBioGRID8643514 |9384571 
|11907583 
c-IAP2 interacts with TRAF2.BIND11907583 
TRAF2MAST2Affinity Capture-WesternBioGRID15308666 
TRAF2RIBC2Two-hybridBioGRID16189514 
TRAF2TNFRSF19-HPRD,BioGRID10809768 
TRAF2TIFATwo-hybridBioGRID16189514 
-HPRD11798190 
TRAF2ITPK1Two-hybridBioGRID16189514 
TRAF2IL15RA-HPRD,BioGRID11064452 
TRAF2CDKN1BTwo-hybridBioGRID16189514 
TRAF2CCDC130Two-hybridBioGRID16189514 
TRAF2ZFAND6Two-hybridBioGRID16189514 
TRAF2SOX9-HPRD12136106 
TRAF2PSMF1Two-hybridBioGRID16189514 
TRAF2TNFRSF13B-HPRD,BioGRID10880535 
TRAF2MAP3K7Affinity Capture-WesternBioGRID14633987 
-HPRD14743216 
TRAF2MAP3K14-HPRD,BioGRID9020361 |11278268 
NIK interacts with TRAF2. This interaction was modeled on a demonstrated interaction between human NIK and TRAF2 from an unspecified species.BIND9275204 
TRAF2CYLDCYLD interacts with TRAF2.BIND12917691 
TRAF2LOC116349Two-hybridBioGRID16189514 
TRAF2TRIM31Two-hybridBioGRID16189514 
TRAF2SOX30Two-hybridBioGRID16189514 
TRAF2CHMP2BTwo-hybridBioGRID16189514 
TRAF2UBXN11Two-hybridBioGRID16189514 
TRAF2PTPN2PTPN2 (TCPTP) interacts with TRAF2.BIND15696169 
TRAF2BIRC2c-IAP1 interacts with and ubiquitinates TRAF2.BIND11907583 
-HPRD8643514 |9384571 
|11907583 
Affinity Capture-Western; in vitro; Reconstituted Complex; Two-hybridBioGRID8643514 |8943045 
|9384571 |11907583 
|16189514 
TRAF2ZBTB25Two-hybridBioGRID16189514 
TRAF2USP2Two-hybridBioGRID16189514 
TRAF2SETD5Two-hybridBioGRID16189514 
TRAF2NGFRAP1-HPRD10514511 
TRAF2MAP3K1Affinity Capture-Western; Co-fractionationBioGRID10346818 
TRAF2DVL2Two-hybridBioGRID16189514 
TRAF2LNX1Two-hybridBioGRID16189514 
TRAF2LOC170082Two-hybridBioGRID16189514 
TRAF2TRAF3IP2Two-hybridBioGRID16189514 
TRAF2MAP3K7Affinity Capture-WesternBioGRID14633987 
-HPRD14743216 
TRAF2BIRC3-HPRD8643514 |11907583 
in vitro; Reconstituted Complex; Two-hybridBioGRID8643514 |9384571 
|11907583 
c-IAP2 interacts with TRAF2.BIND11907583 
TRAF2FLNA-HPRD,BioGRID10617615 
TRAF2NRIP1Two-hybridBioGRID16189514 
TRAF2RGS14Two-hybridBioGRID16189514 
TRAF2CDCA3Two-hybridBioGRID16189514 
TRAF2GORASP2Two-hybridBioGRID16189514 
TRAF2KIAA0408Two-hybridBioGRID16189514 
TRAF2TRIM37-HPRD,BioGRID11279055 
TRAF2MAP3K7IP1Affinity Capture-MSBioGRID14743216 
TRAF2ERN1-HPRD,BioGRID10650002 |12843613 
TRAF2MIZFTwo-hybridBioGRID16189514 
TRAF2SPATA2Two-hybridBioGRID16189514 
TRAF2DTNBTwo-hybridBioGRID16189514 
TRAF2IKBKB-HPRD,BioGRID11359906 
TRAF2IRF4Two-hybridBioGRID16189514 
TRAF2TRPC4APAffinity Capture-WesternBioGRID14585990 
TRAF2TNFRSF8-HPRD8943059 |8999898 
-HPRD,BioGRID8627180 |8943059 
|8999898 |9168896 
|9353251 |11971184|8943059 
|8999898 
TRAF2 interacts with CD30.BIND8662842 
TRAF2BANPTwo-hybridBioGRID16189514 
TRAF2TNFRSF1BTRAF2 interacts with TRAF1. This interaction was modeled on a demonstrated interaction between human TRAF2 and TNF-R2 from an unspecified species.BIND8702708 
-HPRD7639698 |8702708 
|9461607 |11907088 
Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID7639698 |8702708 
|8710854 |9162022 
|11907088 |14743216 
TRAF2BAHD1Two-hybridBioGRID16189514 
TRAF2RFX3Two-hybridBioGRID16189514 
TRAF2TRPT1Two-hybridBioGRID16189514 
TRAF2APEX2Two-hybridBioGRID16189514 
TRAF2TUBA3C-HPRD14743216 
TRAF2ZBTB16Two-hybridBioGRID16189514 
TRAF2CRY1Two-hybridBioGRID16189514 
TRAF2MAP3K7IP3-HPRD,BioGRID14633987 
TRAF2SPG21Two-hybridBioGRID16189514 
TRAF2THAP7Two-hybridBioGRID16189514 
TRAF2MAP4K2-HPRD,BioGRID9712898 
The carboxy-terminal TRAF domain of TRAF2 interacts with the carboxy-terminal domain of GCK.BIND9712898 
TRAF2NIF3L1Two-hybridBioGRID16189514 
TRAF2FBXO28Two-hybridBioGRID16189514 
TRAF2ZNF205Two-hybridBioGRID16189514 
TRAF2TNFRSF9-HPRD,BioGRID9464265 
TRAF2ZBTB43Two-hybridBioGRID16189514 
TRAF2SPHK1-HPRD,BioGRID11777919 
TRAF2TNFRSF18-HPRD,BioGRID10037686 
TRAF2DLGAP5Two-hybridBioGRID16189514 
TRAF2TNFRSF17-HPRD,BioGRID10903733 
TRAF2ZNF646Two-hybridBioGRID16189514 
TRAF2RB1CC1Affinity Capture-WesternBioGRID17015619 
TRAF2ANKRD26L1Two-hybridBioGRID16189514 
TRAF2TNFAffinity Capture-WesternBioGRID12887920 
TRAF2TBK1-HPRD,BioGRID10990461 
TRAF2LTBR-HPRD12169272 
TRAF2 interacts with LTBR.BIND12571250 
Reconstituted ComplexBioGRID9162022 
TRAF2TNFAIP3-HPRD,BioGRID8692885 
TRAF2FAM120BTwo-hybridBioGRID16189514 
TRAF2TNFRSF1BTRAF2 interacts with TRAF1. This interaction was modeled on a demonstrated interaction between human TRAF2 and TNF-R2 from an unspecified species.BIND8702708 
-HPRD7639698 |8702708 
|9461607 |11907088 
Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID7639698 |8702708 
|8710854 |9162022 
|11907088 |14743216 
TRAF2ABLIM1Two-hybridBioGRID16189514 
TRAF2MAP3K8-HPRD,BioGRID11932422 
TRAF2LTBR-HPRD12169272 
TRAF2 interacts with LTBR.BIND12571250 
Reconstituted ComplexBioGRID9162022 
TRAF2MAP3K5-HPRD,BioGRID9774977 |10523862 
TRAF2CD27-HPRD,BioGRID9582383 
TRAF2TRAIP-HPRD,BioGRID9104814 
TRAF2RIPK1-HPRD,BioGRID8612133 |8702708 
TRAF2 ubiquitinates RIP.BIND15258597 
TRAF2 interacts with RIP.BIND8702708 
TRAF2KIAA1267Two-hybridBioGRID16189514 
TRAF2MAP3K14-HPRD,BioGRID9020361 |11278268 
NIK interacts with TRAF2. This interaction was modeled on a demonstrated interaction between human NIK and TRAF2 from an unspecified species.BIND9275204 
TRAF2PIN1Two-hybridBioGRID16189514 
ATXN1ANP32A-HPRD,BioGRID9353121 
ATXN1GAPDH-HPRD,BioGRID8872471 
ATXN1COIL-HPRD,BioGRID12757932 
ATXN1UBQLN4-HPRD,BioGRID11001934 
ATXN1ZHX1Two-hybridBioGRID12659632 
ATXN1PQBP1-HPRD,BioGRID12062018 


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