Protein-protein interaction for CASP4

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Protein-protein interaction data for gene CASP4

Degree = 1
Interactor A Interactor B Experimental method Source Pubmed
CASP4DSP-HPRD15500642 
-HPRD15500642 
CASP4APP-HPRD15123740 
-HPRD15123740 
CASP4IL18Biochemical ActivityBioGRID12096920 
Biochemical ActivityBioGRID12096920 
CASP4SRPRBAffinity Capture-MSBioGRID17353931 
Affinity Capture-MSBioGRID17353931 
CASP4CDK2Affinity Capture-MSBioGRID17353931 
Affinity Capture-MSBioGRID17353931 
CASP4XIAPAffinity Capture-WesternBioGRID11927604 
Affinity Capture-WesternBioGRID11927604 
CASP4SMC2Affinity Capture-MSBioGRID17353931 
Affinity Capture-MSBioGRID17353931 
CASP4IL1F7Biochemical ActivityBioGRID12096920 
Biochemical ActivityBioGRID12096920 
CASP4CASP10-HPRD,BioGRID8962078 
-HPRD,BioGRID8962078 
CASP4MTHFD1LAffinity Capture-MSBioGRID17353931 
Affinity Capture-MSBioGRID17353931 
CASP4CASP4-HPRD,BioGRID10872455 
-HPRD,BioGRID10872455 
CASP4GSNAffinity Capture-MSBioGRID17353931 
Affinity Capture-MSBioGRID17353931 
CASP4KIAA0776Affinity Capture-MSBioGRID17353931 
Affinity Capture-MSBioGRID17353931 
CASP4PSEN1PS1 interacts with caspase 4. This interaction was modeled on a demonstrated interaction between human PS1 and mouse caspase 4.BIND10069390 
PS1 interacts with caspase 4. This interaction was modeled on a demonstrated interaction between human PS1 and mouse caspase 4.BIND10069390 
CASP4EIF2S3Affinity Capture-MSBioGRID17353931 
Affinity Capture-MSBioGRID17353931 
CASP4CASP14-HPRD,BioGRID9792675 
-HPRD,BioGRID9792675 
CASP4NUP93Affinity Capture-MSBioGRID17353931 
Affinity Capture-MSBioGRID17353931 
CASP4APAF1-HPRD,BioGRID9539746 
-HPRD,BioGRID9539746 
CASP4PSMB1Affinity Capture-MSBioGRID17353931 
Affinity Capture-MSBioGRID17353931 
CASP4GCN1L1Affinity Capture-MSBioGRID17353931 
Affinity Capture-MSBioGRID17353931 
CASP4CASP8Biochemical ActivityBioGRID8962078 
Biochemical ActivityBioGRID8962078 
CASP4CASP1Reconstituted ComplexBioGRID10477277 
Reconstituted ComplexBioGRID10477277 
CASP4MSH6Affinity Capture-MSBioGRID17353931 
Affinity Capture-MSBioGRID17353931 
CASP4MYCBPAPAffinity Capture-MSBioGRID17353931 
Affinity Capture-MSBioGRID17353931 
CASP4NOD1-HPRD,BioGRID10329646 
-HPRD,BioGRID10329646 
CASP4SERPINB9-HPRD10477277 
-HPRD10477277 
CASP4HEATR2Affinity Capture-MSBioGRID17353931 
Affinity Capture-MSBioGRID17353931 
CASP4VDAC3Affinity Capture-MSBioGRID17353931 
Affinity Capture-MSBioGRID17353931 
CASP4SMC3Affinity Capture-MSBioGRID17353931 
Affinity Capture-MSBioGRID17353931 
CASP4SMC1AAffinity Capture-MSBioGRID17353931 
Affinity Capture-MSBioGRID17353931 
CASP4SLC25A22Affinity Capture-MSBioGRID17353931 
Affinity Capture-MSBioGRID17353931 
CASP4USP9XAffinity Capture-MSBioGRID17353931 
Affinity Capture-MSBioGRID17353931 
CASP4CTNNBIP1Affinity Capture-MSBioGRID17353931 
Affinity Capture-MSBioGRID17353931 

Degree = 2
Interactor A Interactor B Experimental method Source Pubmed
DSPPKP3PKP3 interacts with DSP(DP)BIND12707304 
Two-hybridBioGRID12707304 
DSPCDH5-HPRD,BioGRID9739078 
DSPNFKBIB-HPRD14743216 
DSPJUP-HPRD,BioGRID9348293 
Plakoglobin interacts with desmoplakin.BIND12426320 
DSPNFKB1-HPRD14743216 
DSPPKP2-HPRD,BioGRID11790773 
DSPDSC1-HPRD,BioGRID9606214 
DSPIVLReconstituted ComplexBioGRID8999895 
DSPPECAM1-HPRD,BioGRID10801826 
DSPPKP3PKP3 interacts with DSP(DP)BIND12707304 
Two-hybridBioGRID12707304 
DSPPKP1-HPRD,BioGRID10852826 
DSPKRT1-HPRD,BioGRID9261168 
DSPCASP2-HPRD15500642 
DSPRELB-HPRD14743216 
DSPJUP-HPRD,BioGRID9348293 
Plakoglobin interacts with desmoplakin.BIND12426320 
DSPEVPL-HPRD8999895 
DSPNFKB2-HPRD14743216 
DSPCASP7-HPRD15500642 
DSPARID3A-HPRD9780002 
DSPIKBKE-HPRD14743216 
DSPCSTAReconstituted ComplexBioGRID8999895 
DSPSTK24Affinity Capture-MSBioGRID17353931 
DSPVIM-HPRD,BioGRID9261168 
DSPPKP4p0071 interacts with desmoplakin.BIND12426320 
Two-hybridBioGRID12615965 
DSPCASP9-HPRD15500642 
DSPDES-HPRD,BioGRID9261168 
DSPCASP6-HPRD15500642 
DSPPKP4p0071 interacts with desmoplakin.BIND12426320 
Two-hybridBioGRID12615965 
APPKNG1-HPRD12090937 
APPCAV1-HPRD,BioGRID9553108 
APPBCAP31-HPRD,BioGRID12529377 
APPLRP1-HPRD7543026 |12212791 
APPAPBA1-HPRD,BioGRID8887653 
APPswe interacts with X11-alpha.BIND12849748 |14756819 
Beta-APP interacts with X11.BIND8887653 
APPBGN-HPRD,BioGRID7793988 
APPHMOX2-HPRD12057765 
APPPRSS3-HPRD11827488 
APPAPBB3-HPRD,BioGRID10081969|14527950 
APPKAT5-HPRD12888553 
APPAPBB1Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID8855266 |8887653 
|9045663 |9837937 
|10081969 
-HPRD8887653 |8955346 
|9045663 |9799084 
|9837937 |11085987 
APPCOL4A5-HPRD9136074 
APPLRP1B-HPRD15126508 
APPGRB2-HPRD12485888 
APPNUMB-HPRD12011466 
APPCALR-HPRD,BioGRID11378243 
APPNCSTN-HPRD,BioGRID10993067 
APPAPBB1Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID8855266 |8887653 
|9045663 |9837937 
|10081969 
-HPRD8887653 |8955346 
|9045663 |9799084 
|9837937 |11085987 
APPSHC1-HPRD,BioGRID9045663 |11877420 
APPDAB2Reconstituted ComplexBioGRID11247302 
APPTP53BP2-HPRD11278849 
APPTM2D1-HPRD11278849 
APPAPBA3-HPRD,BioGRID10049767 
APPTGFB2TGF-beta-2 interacts with Amyloid-beta. This interaction was modelled on a demonstrated interaction between TGF-beta-2 from an unspecified species and consensus Amyloid-beta peptides.BIND12867422 
APPHADHB-HPRD11430884 
APPTGFB1TGF-beta-1 interacts with Amyloid-beta. This interaction was modelled on a demonstrated interaction between TGF-beta-1 from an unspecified species and consensus Amyloid-beta peptides.BIND12867422 
APPKLC1-HPRD,BioGRID11144355 
APPHSD17B10-HPRD,BioGRID9338779 |10371197 
APPABL1-HPRD11279131 
APPMAPK8IP1JIP1 interacts with APP.BIND11724784 
-HPRD11517249 |11724784 
APPCOL4A2-HPRD9136074 
APPFBLN1-HPRD,BioGRID11238726 
APPHSPG2-HPRD9136074 
APPAPBB2-HPRD,BioGRID8855266 |14527950 
APPAPOE-HPRD10559559 
APPSERPINA3-HPRD2190106|10048303 
APPAPBA2-HPRD,BioGRID9890987 
APPPRSS2-HPRD8478942 
APPAPBA1-HPRD,BioGRID8887653 
APPswe interacts with X11-alpha.BIND12849748 |14756819 
Beta-APP interacts with X11.BIND8887653 
APPCOL4A6-HPRD9136074 
APPMAPK8IP1JIP1 interacts with APP.BIND11724784 
-HPRD11517249 |11724784 
APPCLSTN1-HPRD,BioGRID15037614 
APPDAB1-HPRD,BioGRID10460257 
-HPRD9837937 |10460257 
APPCOL25A1-HPRD,BioGRID11927537 
APPSNCA-HPRD,BioGRID9163350 
APPACHE-HPRD,BioGRID12427014 
APPSHC3-HPRD11877420 
APPCOL1A2-HPRD7688497 
APPLAMA1-HPRD9136074 
APPDAB1-HPRD,BioGRID10460257 
-HPRD9837937 |10460257 
APPGAPDH-HPRD8473906 
APPNAE1The carboxy terminus of Amyloid Precursor Protein (APP) mediates an interaction with APP-BP1.BIND8626687 
-HPRD,BioGRID8626687 
APPAPBA1-HPRD,BioGRID8887653 
APPswe interacts with X11-alpha.BIND12849748 |14756819 
Beta-APP interacts with X11.BIND8887653 
APPSNCB-HPRD,BioGRID9163350 
APPCOL4A1-HPRD9136074 
APPF12-HPRD11589915 
APPNID1-HPRD11376898 
APPPSEN2PS2 interacts with APP.BIND9223340 
APPHTRA2HtrA2 interacts with APP.BIND15036614 
APPIDE-HPRD9830016 
APPBLMH-HPRD,BioGRID10973933 
APPSPON1-HPRD14983046 
APPNAE1The carboxy terminus of Amyloid Precursor Protein (APP) mediates an interaction with APP-BP1.BIND8626687 
-HPRD,BioGRID8626687 
APPCOL4A3-HPRD9136074 
APPAPPBP2-HPRD,BioGRID9843960 
IL18IL1RL2-HPRD9325300 
IL18IL18R1-HPRD9325300 
IL18IL18RAP-HPRD9792649 
IL18IL18BP-HPRD,BioGRID11907126 
SRPRBUQCRC1Affinity Capture-MSBioGRID17353931 
SRPRBNFKBIB-HPRD14743216 
SRPRBTSC22D1Affinity Capture-MSBioGRID17353931 
SRPRBNDNAffinity Capture-MSBioGRID17353931 
SRPRBPTP4A3Affinity Capture-MSBioGRID17353931 
CDK2C12orf30Affinity Capture-MSBioGRID17353931 
CDK2MS4A3-HPRD,BioGRID11781350 
CDK2UBTF-HPRD11698641 
CDK2CHAF1B-HPRD10938080 
CDK2CEBPA-HPRD,BioGRID11684017 
CDK2CDKN1Ap21WAF1 interacts with an unspecified isoform of Cdk2. This interaction was modelled on a demonstrated interaction between human p21WAF1 and Cdk2 from an unspecified species.BIND7780738 
p21 interacts with an unspecified isoform of Cdk2.BIND11302688 
p21 interacts with CDK2. This interaction was modeled on a demonstrated interaction between human p21 and hamster CDK2.BIND9467962 
p21 interacts with Cdk2.BIND9546435 
-HPRD,BioGRID12839982 
CDK2PFTK2Affinity Capture-MSBioGRID17353931 
CDK2RBL2-HPRD,BioGRID9188854 
CDK2BCL2-HPRD15619620 
CDK2CKS1B-HPRD,BioGRID8601310 |12140288 
CDK2CDK2AP1-HPRD,BioGRID10938106 
CDK2RRN3Reconstituted ComplexBioGRID15004009 
CDK2E2F1-HPRD,BioGRID7969176 
CDK2VHLAffinity Capture-MSBioGRID17353931 
CDK2WDR8Affinity Capture-MSBioGRID17353931 
CDK2RB1CDK2 phosphorylates Rb carboxy-terminus.BIND15241418 
Biochemical ActivityBioGRID10938106 
CDK2CDC6Affinity Capture-WesternBioGRID9566895 
CDK2SMAD2CDK2 phosphorylates Smad2. This interaction was modelled on a demonstrated interaction between Smad2 from an unspecified species and human CDK2.BIND15241418 
CDK2FBLAffinity Capture-MSBioGRID17353931 
CDK2CDKN1Ap21WAF1 interacts with an unspecified isoform of Cdk2. This interaction was modelled on a demonstrated interaction between human p21WAF1 and Cdk2 from an unspecified species.BIND7780738 
p21 interacts with an unspecified isoform of Cdk2.BIND11302688 
p21 interacts with CDK2. This interaction was modeled on a demonstrated interaction between human p21 and hamster CDK2.BIND9467962 
p21 interacts with Cdk2.BIND9546435 
-HPRD,BioGRID12839982 
CDK2BCCIPAffinity Capture-WesternBioGRID10878006 
CDK2CDKN1Bp27 interacts with an unspecified isoform of CDK2.BIND15652749 
Cdk2 interacts with p27kip1.BIND15619620 
-HPRD,BioGRID12972555 
Cdk2 interacts with p27.BIND15469821 
CDK2PPM1BBiochemical Activity; Co-purificationBioGRID10934208 
CDK2CDKN1Ap21WAF1 interacts with an unspecified isoform of Cdk2. This interaction was modelled on a demonstrated interaction between human p21WAF1 and Cdk2 from an unspecified species.BIND7780738 
p21 interacts with an unspecified isoform of Cdk2.BIND11302688 
p21 interacts with CDK2. This interaction was modeled on a demonstrated interaction between human p21 and hamster CDK2.BIND9467962 
p21 interacts with Cdk2.BIND9546435 
-HPRD,BioGRID12839982 
CDK2SKP2Affinity Capture-Western; Reconstituted ComplexBioGRID10559858 |15355997 
-HPRD10386600 
CDK2PRKCH-HPRD,BioGRID11175348 
CDK2PTMA-HPRD11310559 
CDK2CCNA2Interaction between Cyclin A2 (PDB ID: 1JST_D) and CDK2 (PDB ID: 1JST_A).BIND8756328 
Interaction between CDK2 (PDB ID: 1JST_C) and Cyclin A2 (PDB ID: 1JST_B).BIND8756328 
Affinity Capture-WesternBioGRID12853968 
Interaction between Cyclin A2 (PDB ID: 1JST_D) and CDK2 (PDB ID: 1JST_C).BIND8756328 
CDK2 interacts with CCNA2 (cyclin A) to form a complex.BIND8475101 
-HPRD10924145 |11907280|11907280 
CCNA2 (cyclin A) interacts with Cdk2.BIND8662825 
Cdk2 interacts with Cyc A.BIND15469821 
Cyclin A interacts with cdk2.BIND9632134 
CDK2SKP2Affinity Capture-Western; Reconstituted ComplexBioGRID10559858 |15355997 
-HPRD10386600 
CDK2XRCC6Biochemical ActivityBioGRID15159402 
CDK2CDKN1Bp27 interacts with an unspecified isoform of CDK2.BIND15652749 
Cdk2 interacts with p27kip1.BIND15619620 
-HPRD,BioGRID12972555 
Cdk2 interacts with p27.BIND15469821 
CDK2CDKN3Affinity Capture-Western; in vitro; Two-hybridBioGRID7569954 |8127873 
|8242750 |8242751 
|12745075 
-HPRD11463386 |12745075 
-HPRD7569954 |8242750 
|8242751 
CDK2CCNB3-HPRD,BioGRID12185076 
CDK2CCNE2-HPRD,BioGRID9858585 
-HPRD9858585 |15232106 
CDK2RBM4Biochemical ActivityBioGRID15159402 
CDK2BRCA1BRCA1 associates with CDK2BIND9244350 |10373534 
Affinity Capture-Western; Reconstituted ComplexBioGRID8764100 |9244350 
|10373534 
CDK2NEDD8Affinity Capture-MSBioGRID17353931 
CDK2UBE2MAffinity Capture-MSBioGRID17353931 
CDK2BIRC5Affinity Capture-WesternBioGRID11069302 
CDK2SMAD3CDK2 phosphorylates Smad3 on Thr8, Thr179, Ser204, Ser208 and Ser213. This interaction was modelled on a demonstrated interaction between Smad3 from an unspecified species and human CDK2.BIND15241418 
CDK2CCNA2Interaction between Cyclin A2 (PDB ID: 1JST_D) and CDK2 (PDB ID: 1JST_A).BIND8756328 
Interaction between CDK2 (PDB ID: 1JST_C) and Cyclin A2 (PDB ID: 1JST_B).BIND8756328 
Affinity Capture-WesternBioGRID12853968 
Interaction between Cyclin A2 (PDB ID: 1JST_D) and CDK2 (PDB ID: 1JST_C).BIND8756328 
CDK2 interacts with CCNA2 (cyclin A) to form a complex.BIND8475101 
-HPRD10924145 |11907280|11907280 
CCNA2 (cyclin A) interacts with Cdk2.BIND8662825 
Cdk2 interacts with Cyc A.BIND15469821 
Cyclin A interacts with cdk2.BIND9632134 
CDK2RB1CDK2 phosphorylates Rb carboxy-terminus.BIND15241418 
Biochemical ActivityBioGRID10938106 
CDK2CABLES1-HPRD11585773 
CDK2INCA1Biochemical ActivityBioGRID15159402 
CDK2ORC2L-HPRD15232106 
Biochemical ActivityBioGRID11931757 
CDK2CNOT7-HPRD,BioGRID10602502 
CDK2EPB41Affinity Capture-MSBioGRID17353931 
CDK2CCNA1-HPRD,BioGRID9041194 |10559988 
CCNA1 (CYCA) interacts with unspecified isoform of CDK2.BIND8463339 
CDK2NPDC1-HPRD,BioGRID11042687 
CDK2POLA1Biochemical ActivityBioGRID10877824 
CDK2SPDYA-HPRD11980914 |12839962 
Affinity Capture-WesternBioGRID12972555 
CDK2CCNA2Interaction between Cyclin A2 (PDB ID: 1JST_D) and CDK2 (PDB ID: 1JST_A).BIND8756328 
Interaction between CDK2 (PDB ID: 1JST_C) and Cyclin A2 (PDB ID: 1JST_B).BIND8756328 
Affinity Capture-WesternBioGRID12853968 
Interaction between Cyclin A2 (PDB ID: 1JST_D) and CDK2 (PDB ID: 1JST_C).BIND8756328 
CDK2 interacts with CCNA2 (cyclin A) to form a complex.BIND8475101 
-HPRD10924145 |11907280|11907280 
CCNA2 (cyclin A) interacts with Cdk2.BIND8662825 
Cdk2 interacts with Cyc A.BIND15469821 
Cyclin A interacts with cdk2.BIND9632134 
CDK2CCNA2Interaction between Cyclin A2 (PDB ID: 1JST_D) and CDK2 (PDB ID: 1JST_A).BIND8756328 
Interaction between CDK2 (PDB ID: 1JST_C) and Cyclin A2 (PDB ID: 1JST_B).BIND8756328 
Affinity Capture-WesternBioGRID12853968 
Interaction between Cyclin A2 (PDB ID: 1JST_D) and CDK2 (PDB ID: 1JST_C).BIND8756328 
CDK2 interacts with CCNA2 (cyclin A) to form a complex.BIND8475101 
-HPRD10924145 |11907280|11907280 
CCNA2 (cyclin A) interacts with Cdk2.BIND8662825 
Cdk2 interacts with Cyc A.BIND15469821 
Cyclin A interacts with cdk2.BIND9632134 
CDK2CDKN3Affinity Capture-Western; in vitro; Two-hybridBioGRID7569954 |8127873 
|8242750 |8242751 
|12745075 
-HPRD11463386 |12745075 
-HPRD7569954 |8242750 
|8242751 
CDK2RBL1Biochemical Activity; in vitro; in vivoBioGRID9891079 |11884610 
-HPRD8230483|11884610 
CDK2CDKN1Ap21WAF1 interacts with an unspecified isoform of Cdk2. This interaction was modelled on a demonstrated interaction between human p21WAF1 and Cdk2 from an unspecified species.BIND7780738 
p21 interacts with an unspecified isoform of Cdk2.BIND11302688 
p21 interacts with CDK2. This interaction was modeled on a demonstrated interaction between human p21 and hamster CDK2.BIND9467962 
p21 interacts with Cdk2.BIND9546435 
-HPRD,BioGRID12839982 
CDK2MYBL2Biochemical ActivityBioGRID11264176 
CDK2MCM3-HPRD15232106 
CDK2FAM113AAffinity Capture-MSBioGRID17353931 
CDK2CDC25A-HPRD,BioGRID8617791 
CDK2FEN1-HPRD,BioGRID12853968 
CDK2CDKN1Ap21WAF1 interacts with an unspecified isoform of Cdk2. This interaction was modelled on a demonstrated interaction between human p21WAF1 and Cdk2 from an unspecified species.BIND7780738 
p21 interacts with an unspecified isoform of Cdk2.BIND11302688 
p21 interacts with CDK2. This interaction was modeled on a demonstrated interaction between human p21 and hamster CDK2.BIND9467962 
p21 interacts with Cdk2.BIND9546435 
-HPRD,BioGRID12839982 
CDK2UHRF2-HPRD15178429 
CDK2PCNA-HPRD,BioGRID10930425 
CDK2CCNE1-HPRD,BioGRID1388288 
CDK2HIST1H1BAn unspecified isoform of CDK2 phosphorylates H1.BIND7629134 
CDK2LYN-HPRD,BioGRID8806683 |10432313 
CDK2CCNA2Interaction between Cyclin A2 (PDB ID: 1JST_D) and CDK2 (PDB ID: 1JST_A).BIND8756328 
Interaction between CDK2 (PDB ID: 1JST_C) and Cyclin A2 (PDB ID: 1JST_B).BIND8756328 
Affinity Capture-WesternBioGRID12853968 
Interaction between Cyclin A2 (PDB ID: 1JST_D) and CDK2 (PDB ID: 1JST_C).BIND8756328 
CDK2 interacts with CCNA2 (cyclin A) to form a complex.BIND8475101 
-HPRD10924145 |11907280|11907280 
CCNA2 (cyclin A) interacts with Cdk2.BIND8662825 
Cdk2 interacts with Cyc A.BIND15469821 
Cyclin A interacts with cdk2.BIND9632134 
CDK2CCNE2-HPRD,BioGRID9858585 
-HPRD9858585 |15232106 
CDK2CDKN1Bp27 interacts with an unspecified isoform of CDK2.BIND15652749 
Cdk2 interacts with p27kip1.BIND15619620 
-HPRD,BioGRID12972555 
Cdk2 interacts with p27.BIND15469821 
CDK2CDKN3Affinity Capture-Western; in vitro; Two-hybridBioGRID7569954 |8127873 
|8242750 |8242751 
|12745075 
-HPRD11463386 |12745075 
-HPRD7569954 |8242750 
|8242751 
CDK2CCNA2Interaction between Cyclin A2 (PDB ID: 1JST_D) and CDK2 (PDB ID: 1JST_A).BIND8756328 
Interaction between CDK2 (PDB ID: 1JST_C) and Cyclin A2 (PDB ID: 1JST_B).BIND8756328 
Affinity Capture-WesternBioGRID12853968 
Interaction between Cyclin A2 (PDB ID: 1JST_D) and CDK2 (PDB ID: 1JST_C).BIND8756328 
CDK2 interacts with CCNA2 (cyclin A) to form a complex.BIND8475101 
-HPRD10924145 |11907280|11907280 
CCNA2 (cyclin A) interacts with Cdk2.BIND8662825 
Cdk2 interacts with Cyc A.BIND15469821 
Cyclin A interacts with cdk2.BIND9632134 
CDK2CCNA2Interaction between Cyclin A2 (PDB ID: 1JST_D) and CDK2 (PDB ID: 1JST_A).BIND8756328 
Interaction between CDK2 (PDB ID: 1JST_C) and Cyclin A2 (PDB ID: 1JST_B).BIND8756328 
Affinity Capture-WesternBioGRID12853968 
Interaction between Cyclin A2 (PDB ID: 1JST_D) and CDK2 (PDB ID: 1JST_C).BIND8756328 
CDK2 interacts with CCNA2 (cyclin A) to form a complex.BIND8475101 
-HPRD10924145 |11907280|11907280 
CCNA2 (cyclin A) interacts with Cdk2.BIND8662825 
Cdk2 interacts with Cyc A.BIND15469821 
Cyclin A interacts with cdk2.BIND9632134 
CDK2SORT1Affinity Capture-MSBioGRID17353931 
CDK2RADILAffinity Capture-MSBioGRID17353931 
CDK2OGTAffinity Capture-MSBioGRID17353931 
CDK2CCNB1Affinity Capture-WesternBioGRID9891079 
CDK2SPDYA-HPRD11980914 |12839962 
Affinity Capture-WesternBioGRID12972555 
CDK2TP53Biochemical ActivityBioGRID10884347 
CDK2CDK6Co-purificationBioGRID10934208 
CDK2MITFMITF interacts with the CDK2 promoter.BIND15607961 
CDK2RELAffinity Capture-WesternBioGRID9731206 
CDK2PPP2CABiochemical Activity; Co-purificationBioGRID10934208 
CDK2CCNA2Interaction between Cyclin A2 (PDB ID: 1JST_D) and CDK2 (PDB ID: 1JST_A).BIND8756328 
Interaction between CDK2 (PDB ID: 1JST_C) and Cyclin A2 (PDB ID: 1JST_B).BIND8756328 
Affinity Capture-WesternBioGRID12853968 
Interaction between Cyclin A2 (PDB ID: 1JST_D) and CDK2 (PDB ID: 1JST_C).BIND8756328 
CDK2 interacts with CCNA2 (cyclin A) to form a complex.BIND8475101 
-HPRD10924145 |11907280|11907280 
CCNA2 (cyclin A) interacts with Cdk2.BIND8662825 
Cdk2 interacts with Cyc A.BIND15469821 
Cyclin A interacts with cdk2.BIND9632134 
CDK2CDK7CDK7 phosphorylates an unspecified isoform of CDK2.BIND7629134 
CDK2BRCA1BRCA1 associates with CDK2BIND9244350 |10373534 
Affinity Capture-Western; Reconstituted ComplexBioGRID8764100 |9244350 
|10373534 
CDK2RBL1Biochemical Activity; in vitro; in vivoBioGRID9891079 |11884610 
-HPRD8230483|11884610 
CDK2CCNA2Interaction between Cyclin A2 (PDB ID: 1JST_D) and CDK2 (PDB ID: 1JST_A).BIND8756328 
Interaction between CDK2 (PDB ID: 1JST_C) and Cyclin A2 (PDB ID: 1JST_B).BIND8756328 
Affinity Capture-WesternBioGRID12853968 
Interaction between Cyclin A2 (PDB ID: 1JST_D) and CDK2 (PDB ID: 1JST_C).BIND8756328 
CDK2 interacts with CCNA2 (cyclin A) to form a complex.BIND8475101 
-HPRD10924145 |11907280|11907280 
CCNA2 (cyclin A) interacts with Cdk2.BIND8662825 
Cdk2 interacts with Cyc A.BIND15469821 
Cyclin A interacts with cdk2.BIND9632134 
CDK2CDKN1Bp27 interacts with an unspecified isoform of CDK2.BIND15652749 
Cdk2 interacts with p27kip1.BIND15619620 
-HPRD,BioGRID12972555 
Cdk2 interacts with p27.BIND15469821 
CDK2ORC2L-HPRD15232106 
Biochemical ActivityBioGRID11931757 
CDK2ORC1LAffinity Capture-Western; Biochemical ActivityBioGRID11931757 
CDK2CCNA1-HPRD,BioGRID9041194 |10559988 
CCNA1 (CYCA) interacts with unspecified isoform of CDK2.BIND8463339 
CDK2TSC22D1Affinity Capture-MSBioGRID17353931 
CDK2PTP4A3Affinity Capture-MSBioGRID17353931 
XIAPCASP9XIAP interacts with and ubiquitinates Caspase-9.BIND15300255 
Affinity Capture-Western; Far Western; Reconstituted Complex; Two-hybridBioGRID9545235 |11390657 
|15280366 |16189514 
-HPRD9545235 |11927604 
XIAPCASP3-HPRD9230442 |11447297 
|11927604 
XIAP interacts with Casp-3.BIND15200957 
Affinity Capture-Western; Co-crystal Structure; in vitro; in vivo; Reconstituted ComplexBioGRID9230442 |9384571 
|11257232 |11447297 
|11927604 
Caspase-3 interacts with XIAP.BIND15650747 
XIAPMAP3K7IP2-HPRD,BioGRID12048196 
XIAPCASP6XIAP interacts with Casp-6.BIND15200957 
XIAPHTRA2-HPRD,BioGRID11604410 
XIAP interacts with HtrA2.BIND15300255 
XIAPHTRA2-HPRD,BioGRID11604410 
XIAP interacts with HtrA2.BIND15300255 
XIAPXAF1-HPRD,BioGRID11175744 
XIAPCASP3-HPRD9230442 |11447297 
|11927604 
XIAP interacts with Casp-3.BIND15200957 
Affinity Capture-Western; Co-crystal Structure; in vitro; in vivo; Reconstituted ComplexBioGRID9230442 |9384571 
|11257232 |11447297 
|11927604 
Caspase-3 interacts with XIAP.BIND15650747 
XIAPMAP3K7IP1-HPRD,BioGRID9878061 
XIAP interacts with TAB1.BIND9878061 
XIAPDIABLOSmac interacts with XIAP.BIND15650747 
XIAP interacts with and ubiquitinates SMAC.BIND15300255 
-HPRD,BioGRID10929712 
XIAPMAGED1-HPRD,BioGRID11546791 
XIAPCOMMD1-HPRD14685242 
XIAPCASP9XIAP interacts with and ubiquitinates Caspase-9.BIND15300255 
Affinity Capture-Western; Far Western; Reconstituted Complex; Two-hybridBioGRID9545235 |11390657 
|15280366 |16189514 
-HPRD9545235 |11927604 
XIAPMAP3K7-HPRD,BioGRID12048196 
XIAPCASP7XIAP interacts with caspase-7.BIND15580265 
-HPRD9230442 |11359776 
Caspase-7 interacts with XIAP.BIND15650747 
in vitro; in vivo; Reconstituted ComplexBioGRID9230442 |9384571 
|11257232 |11359776 
XIAP interacts with Casp-7.BIND15200957 
XIAPMAP3K7IP1-HPRD,BioGRID9878061 
XIAP interacts with TAB1.BIND9878061 
XIAPTGFBR1TGF-beta-RI interacts with XIAP. This interaction was modeled on a demonstrated interaction between TGF-beta-RI from an unspecified species and human XIAP.BIND11356828 
XIAPDYNLL2Two-hybridBioGRID16189514 
XIAPACVR1BAn unspecified isoform of ALK4 interacts with XIAP. This interaction was modeled on a demonstrated interaction between ALK4 from an unspecified species and human XIAP.BIND11356828 
XIAPACVRL1ALK1 interacts with XIAP. This interaction was modeled on a demonstrated interaction between ALK1 from an unspecified species and human XIAP.BIND11356828 
XIAPDIABLOSmac interacts with XIAP.BIND15650747 
XIAP interacts with and ubiquitinates SMAC.BIND15300255 
-HPRD,BioGRID10929712 
XIAPTRAF6-HPRD,BioGRID12048196 
XIAPCHEK1Reconstituted ComplexBioGRID14759516 
XIAPCASP7XIAP interacts with caspase-7.BIND15580265 
-HPRD9230442 |11359776 
Caspase-7 interacts with XIAP.BIND15650747 
in vitro; in vivo; Reconstituted ComplexBioGRID9230442 |9384571 
|11257232 |11359776 
XIAP interacts with Casp-7.BIND15200957 
XIAPCASP9XIAP interacts with and ubiquitinates Caspase-9.BIND15300255 
Affinity Capture-Western; Far Western; Reconstituted Complex; Two-hybridBioGRID9545235 |11390657 
|15280366 |16189514 
-HPRD9545235 |11927604 
XIAPCASP7XIAP interacts with caspase-7.BIND15580265 
-HPRD9230442 |11359776 
Caspase-7 interacts with XIAP.BIND15650747 
in vitro; in vivo; Reconstituted ComplexBioGRID9230442 |9384571 
|11257232 |11359776 
XIAP interacts with Casp-7.BIND15200957 
XIAPSTRADB-HPRD,BioGRID12048196 
XIAPCASP3-HPRD9230442 |11447297 
|11927604 
XIAP interacts with Casp-3.BIND15200957 
Affinity Capture-Western; Co-crystal Structure; in vitro; in vivo; Reconstituted ComplexBioGRID9230442 |9384571 
|11257232 |11447297 
|11927604 
Caspase-3 interacts with XIAP.BIND15650747 
XIAPGSPT1-HPRD,BioGRID12865429 
XIAPCASP2Phenotypic SuppressionBioGRID11832478 
XIAPCASP3-HPRD9230442 |11447297 
|11927604 
XIAP interacts with Casp-3.BIND15200957 
Affinity Capture-Western; Co-crystal Structure; in vitro; in vivo; Reconstituted ComplexBioGRID9230442 |9384571 
|11257232 |11447297 
|11927604 
Caspase-3 interacts with XIAP.BIND15650747 
XIAPDIABLOSmac interacts with XIAP.BIND15650747 
XIAP interacts with and ubiquitinates SMAC.BIND15300255 
-HPRD,BioGRID10929712 
XIAPCASP7XIAP interacts with caspase-7.BIND15580265 
-HPRD9230442 |11359776 
Caspase-7 interacts with XIAP.BIND15650747 
in vitro; in vivo; Reconstituted ComplexBioGRID9230442 |9384571 
|11257232 |11359776 
XIAP interacts with Casp-7.BIND15200957 
XIAPCASP7XIAP interacts with caspase-7.BIND15580265 
-HPRD9230442 |11359776 
Caspase-7 interacts with XIAP.BIND15650747 
in vitro; in vivo; Reconstituted ComplexBioGRID9230442 |9384571 
|11257232 |11359776 
XIAP interacts with Casp-7.BIND15200957 
XIAPWDYHV1Two-hybridBioGRID16189514 
SMC2PTP4A3Affinity Capture-MSBioGRID17353931 
SMC2SMC4Affinity Capture-WesternBioGRID9789013 
SMC2NCAPD2Affinity Capture-WesternBioGRID10958694 
SMC2DNMT3BCo-purification; Reconstituted ComplexBioGRID15148359 
IL1F7IL18R1Reconstituted ComplexBioGRID12096920 
CASP10MSNCo-purificationBioGRID15659383 
CASP10CASP7-HPRD,BioGRID8962078 
CASP10TNFRSF1A-HPRD11098060 
Affinity Capture-Western; Co-purificationBioGRID9045686 |15659383 
CASP10CFLAR-HPRD9208847 |9228018 
|9289491 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID9228018 |9289491 
|12887920 
CASP10EZRCo-purificationBioGRID15659383 
CASP10BIDCo-purificationBioGRID15659383 
CASP10FAS-HPRD,BioGRID9045686 
CASP10MAPK8Co-purificationBioGRID15659383 
CASP10TRAF1Biochemical ActivityBioGRID11098060 
CASP10RB1CASP10 (caspase-10) cleaves RB-1 (hRB) at the DSID consensus site to produce the p68 form.BIND15735701 
CASP10RIPK1Affinity Capture-WesternBioGRID11002417 
CASP10DEDD-HPRD,BioGRID12527898 
CASP10BFAR-HPRD10716992 
CASP10CASP3Biochemical ActivityBioGRID8962078 
CASP10CASP6-HPRD,BioGRID8962078 
CASP10CFLAR-HPRD9208847 |9228018 
|9289491 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID9228018 |9289491 
|12887920 
CASP10TNFRSF10BAffinity Capture-Western; Co-purificationBioGRID9325248 |15659383 
CASP10TNFRSF1A-HPRD11098060 
Affinity Capture-Western; Co-purificationBioGRID9045686 |15659383 
CASP10MAP3K14Affinity Capture-WesternBioGRID11002417 
CASP10RYBP-HPRD,BioGRID11395500 
CASP10RHOACo-purificationBioGRID15659383 
CASP10TNFRSF10AAffinity Capture-WesternBioGRID9325248 
CASP10CASP9-HPRD,BioGRID8962078 
CASP10FADD-HPRD9045686 |11717445|11717445 
-HPRD,BioGRID11717445 
CASP10CASP2-HPRD,BioGRID8962078 
CASP10FASLGCo-purificationBioGRID15659383 
CASP10ARHGDIACo-purificationBioGRID15659383 
CASP10CCAR1-HPRD15069192 
CASP10FADD-HPRD9045686 |11717445|11717445 
-HPRD,BioGRID11717445 
CASP10DEDD2-HPRD,BioGRID12527898 
MTHFD1LMAGED1Affinity Capture-MSBioGRID17353931 
MTHFD1LWDR8Affinity Capture-MSBioGRID17353931 
GSNFN1-HPRD,BioGRID6092370 
GSNVASP-HPRD11093254 
GSNPXN-HPRD,BioGRID11577104 
GSNSTK39Two-hybridBioGRID14563843 
GSNSRCAffinity Capture-WesternBioGRID11577104 
GSNVCL-HPRD,BioGRID11577104 
GSNTNIK-HPRD10521462 
GSNPTK2B-HPRD,BioGRID12578912 
GSNAR-HPRD,BioGRID12941811 
GSNCLIC5-HPRD10793131 
GSNPIK3CAAffinity Capture-WesternBioGRID11577104 
GSNLIMK2-HPRD11171090 
GSNPLCG1Reconstituted ComplexBioGRID9164868 
GSNBCAR1-HPRD11577104 
GSNACTB-HPRD10945978 
GSNVDAC1-HPRD,BioGRID11039896 
GSNACTA1-HPRD,BioGRID10583954 
GSNPTK2Affinity Capture-WesternBioGRID11577104 
GSNPTPN12Affinity Capture-WesternBioGRID11577104 
GSNPPM1BAffinity Capture-MSBioGRID17353931 
GSNTOM1L1Two-hybridBioGRID16169070 
GSNACTN4-HPRD,BioGRID11733011 
KIAA0776CDK5RAP3Affinity Capture-MSBioGRID17353931 
PSEN1APH1AAPH-1A interacts with PSEN1.BIND12297508 
Affinity Capture-Western; Co-fractionationBioGRID12297508 |12471034 
|14572442 
PSEN1ERN1-HPRD,BioGRID10587643 
PSEN1STX5The full-length PS1 holoprotein interacts with Syntaxin 5.BIND15109302 
PSEN1PSENENPEN-2 interacts with PS1.BIND15322109 
-HPRD,BioGRID12198112 |12639958 
PSEN1ICAM5-HPRD,BioGRID11719200 
PSEN1NOTCH1Affinity Capture-WesternBioGRID10077672 
PSEN1PSEN2Affinity Capture-WesternBioGRID12471034 
PSEN1CTNNB1Affinity Capture-WesternBioGRID9738936 |9852041 
|10341227 
PS1 interacts with beta-catenin.BIND9632714 
PSEN1PSENENPEN-2 interacts with PS1.BIND15322109 
-HPRD,BioGRID12198112 |12639958 
PSEN1CDH1Affinity Capture-WesternBioGRID10635315 
PSEN1KCNIP3Affinity Capture-WesternBioGRID9771752 |10854253 
-HPRD12207970 
PSEN1YME1L1-HPRD,BioGRID12214059 
PSEN1TCF7L2-HPRD,BioGRID11504726 
PSEN1CLSTN1Affinity Capture-WesternBioGRID15037614 
PSEN1STX1APS1 interacts with syntaxin 1A.BIND10891589 
PSEN1CTNND2PS1 interacts with NPRAPBIND10037471 
PSEN1FLNBReconstituted Complex; Two-hybridBioGRID9437013 
PSEN1BCL2-HPRD,BioGRID10521466 
PSEN1CASP3PS1 interacts with caspase 3. This interaction was modeled on a demonstrated interaction between human PS1 and mouse caspase 3.BIND10069390 
PSEN1NCSTNPS1 interacts with Nicastrin.BIND10993067 
Affinity Capture-WesternBioGRID10993067 |12297508 
|12471034 |14572442 
|15257293 
PSEN1MTCH1-HPRD10551805 
PSEN1CASP7PS1 interacts with caspase 7. This interaction was modeled on a demonstrated interaction between human PS1 and mouse caspase 7.BIND10069390 
PSEN1CIB1Two-hybridBioGRID10366599 
PSEN1METTL2BTwo-hybridBioGRID11738826 
PSEN1APBA1-HPRD12196555 
PSEN1BCL2L1-HPRD,BioGRID10446169 
PSEN1PKP4-HPRD,BioGRID10037471 |10092585 
PSEN1HERPUD1-HPRD,BioGRID11799129 
PSEN1KCNIP3Affinity Capture-WesternBioGRID9771752 |10854253 
-HPRD12207970 
PSEN1GFAP-HPRD,BioGRID12058025 
PSEN1FBXW7Affinity Capture-WesternBioGRID12354302 
PSEN1NCSTNPS1 interacts with Nicastrin.BIND10993067 
Affinity Capture-WesternBioGRID10993067 |12297508 
|12471034 |14572442 
|15257293 
PSEN1CTNNA1Affinity Capture-WesternBioGRID10635315 
PSEN1CTNNB1Affinity Capture-WesternBioGRID9738936 |9852041 
|10341227 
PS1 interacts with beta-catenin.BIND9632714 
PSEN1APH1AAPH-1A interacts with PSEN1.BIND12297508 
Affinity Capture-Western; Co-fractionationBioGRID12297508 |12471034 
|14572442 
PSEN1KCNIP4Two-hybridBioGRID11847232 
PSEN1UBQLN1Reconstituted Complex; Two-hybridBioGRID11076969 
PSEN1CTNND1Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID10208590 
PSEN1DOCK3-HPRD10854253 
PSEN1MAPT-HPRD,BioGRID9689133 
PSEN1APH1B-HPRD12471034 
EIF2S3EIF1BAffinity Capture-MSBioGRID17353931 
EIF2S3CTCFCTCF interacts with the EIF2S3 5' end chromatin.BIND15669143 
EIF2S3H3F3AAcetylated histone 3 (AceH3) interacts with EIF2S3 5' end chromatin.BIND15669143 
EIF2S3METAP2-HPRD,BioGRID8098621 
CASP14CASP2-HPRD,BioGRID9792675 
NUP93NEK6Affinity Capture-MSBioGRID17353931 
NUP93BRF2Affinity Capture-MSBioGRID17353931 
NUP93PHLDA3Affinity Capture-MSBioGRID17353931 
NUP93PHB2Affinity Capture-MSBioGRID17353931 
NUP93TSC22D1Affinity Capture-MSBioGRID17353931 
NUP93GIPC1Affinity Capture-MSBioGRID17353931 
NUP93MYCAffinity Capture-MSBioGRID17353931 
NUP93TPRAffinity Capture-WesternBioGRID12802065 
NUP93NUP205-HPRD9348540 
NUP93PNKPAffinity Capture-MSBioGRID17353931 
APAF1HSPA1A-HPRD10934467 
APAF1APIP-HPRD,BioGRID15262985 
APAF1CYCS-HPRD,BioGRID9267021|12147322 
APAF1HSPA4Affinity Capture-Western; Co-purification; Reconstituted ComplexBioGRID10934467 
APAF1AVEN-HPRD,BioGRID10949025 
APAF1BCL2L1-HPRD,BioGRID9488720 |9539746 
APAF1NLRP1-HPRD,BioGRID11113115 
APAF1HSP90AA1Affinity Capture-WesternBioGRID10934467 
APAF1CASP9-HPRD,BioGRID9390557 |9488720 
APAF1 interacts with CASP9.BIND15829969 
-HPRD9390557 |9488720 
|9539746 |9837928 
|10376594 
APAF1CASP9-HPRD,BioGRID9390557 |9488720 
APAF1 interacts with CASP9.BIND15829969 
-HPRD9390557 |9488720 
|9539746 |9837928 
|10376594 
APAF1FEM1B-HPRD10764728 
APAF1CASP9-HPRD,BioGRID9390557 |9488720 
APAF1 interacts with CASP9.BIND15829969 
-HPRD9390557 |9488720 
|9539746 |9837928 
|10376594 
APAF1BCL2L10-HPRD9829980 |9878060 
|10486928 
PSMB1RIPK5Affinity Capture-MSBioGRID17353931 
PSMB1DCP2Two-hybridBioGRID15231747 
PSMB1VHLAffinity Capture-MSBioGRID17353931 
PSMB1PASKAffinity Capture-MSBioGRID17353931 
PSMB1PLK1-HPRD,BioGRID11205743 
PSMB1RIOK3Affinity Capture-MSBioGRID17353931 
PSMB1FANCGTwo-hybridBioGRID14499622 
PSMB1EXOSC6-HPRD,BioGRID15231747 
PSMB1PSMA2-HPRD10436176 
GCN1L1TSC22D1Affinity Capture-MSBioGRID17353931 
GCN1L1PTP4A3Affinity Capture-MSBioGRID17353931 
GCN1L1C20orf24Affinity Capture-MSBioGRID17353931 
GCN1L1BRF2Affinity Capture-MSBioGRID17353931 
GCN1L1RELA-HPRD14743216 
GCN1L1MAGED1Affinity Capture-MSBioGRID17353931 
GCN1L1MAST2Affinity Capture-MSBioGRID17353931 
GCN1L1IKBKG-HPRD14743216 
GCN1L1TNFRSF1A-HPRD14743216 
GCN1L1TNFRSF14Affinity Capture-MSBioGRID17353931 
GCN1L1MYCAffinity Capture-MSBioGRID17353931 
GCN1L1MAGEA6Affinity Capture-MSBioGRID17353931 
GCN1L1TNFRSF1B-HPRD14743216 
GCN1L1NEK6Affinity Capture-MSBioGRID17353931 
CASP8FAS-HPRD11101867 
Affinity Capture-Western; Co-purificationBioGRID9208847 |9325248 
|15659383 
CASP8CFLARMRIT-beta-1 interacts with FLICE. This interaction was modelled on a demonstrated interaction between human MRIT-beta-1 and FLICE from an unspecified species.BIND9326610 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID9208847 |9228018 
|9289491 |9326610 
|11741985 |12215447 
|12887920 
-HPRD9208847 |9289491 
|12215447 
MRIT-alpha-1 interacts with FLICE. This interaction was modelled on a demonstrated interaction between human MRIT-alpha-1 and FLICE from an unspecified species.BIND9326610 
CASP8TRAF2Affinity Capture-WesternBioGRID12887920 
CASP8RIPK1-HPRD,BioGRID11002417 
CASP8CHUK-HPRD,BioGRID11002417 
CASP8BCAP31-HPRD,BioGRID9334338 
CASP8ARAndrogen Receptor interacts with caspase 8.BIND9535906 
CASP8CASP3Biochemical ActivityBioGRID8962078 |11832478 
CASP8BCL2L1-HPRD11733517 
Phenotypic SuppressionBioGRID11832478 
CASP8HIP1-HPRD,BioGRID11788820 
CASP8ATN1Atrophin-1 interacts with caspase 8.BIND9535906 
CASP8MAPK8Co-purificationBioGRID15659383 
CASP8IFT57-HPRD,BioGRID11788820 
CASP8TNFRSF10AAffinity Capture-WesternBioGRID9325248 
-HPRD12218097 
CASP8BCL2-HPRD,BioGRID11406564 
CASP8RHOACo-purificationBioGRID15659383 
CASP8VIMTwo-hybridBioGRID16169070 
CASP8CTNNB1-HPRD12189238 
CASP8CASP7Biochemical ActivityBioGRID8962078 |11832478 
CASP8EZRCo-purificationBioGRID15659383 
CASP8CDC2L2-HPRD9632733 
CASP8CFLARMRIT-beta-1 interacts with FLICE. This interaction was modelled on a demonstrated interaction between human MRIT-beta-1 and FLICE from an unspecified species.BIND9326610 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID9208847 |9228018 
|9289491 |9326610 
|11741985 |12215447 
|12887920 
-HPRD9208847 |9289491 
|12215447 
MRIT-alpha-1 interacts with FLICE. This interaction was modelled on a demonstrated interaction between human MRIT-alpha-1 and FLICE from an unspecified species.BIND9326610 
CASP8TNFRSF10AAffinity Capture-WesternBioGRID9325248 
-HPRD12218097 
CASP8TNFRSF1ACo-purificationBioGRID15659383 
CASP8RYBP-HPRD11395500 
CASP8CFLARMRIT-beta-1 interacts with FLICE. This interaction was modelled on a demonstrated interaction between human MRIT-beta-1 and FLICE from an unspecified species.BIND9326610 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID9208847 |9228018 
|9289491 |9326610 
|11741985 |12215447 
|12887920 
-HPRD9208847 |9289491 
|12215447 
MRIT-alpha-1 interacts with FLICE. This interaction was modelled on a demonstrated interaction between human MRIT-alpha-1 and FLICE from an unspecified species.BIND9326610 
CASP8IKBKB-HPRD,BioGRID11002417 
CASP8DEDD-HPRD,BioGRID12527898 
CASP8CASP6-HPRD,BioGRID12232792 
CASP8CHD3Two-hybridBioGRID16169070 
CASP8TNFRSF10BAffinity Capture-Western; Co-purificationBioGRID9325248 |15659383 
-HPRD12218097 
CASP8BFAR-HPRD10716992 
CASP8BIRC2Affinity Capture-WesternBioGRID12887920 
CASP8FAS-HPRD11101867 
Affinity Capture-Western; Co-purificationBioGRID9208847 |9325248 
|15659383 
CASP8MSNCo-purificationBioGRID15659383 
CASP8PEA15-HPRD,BioGRID10442631 |10493725 
CASP8BIDBiochemical Activity; Co-purificationBioGRID11832478 |15659383 
CASP8TRAF1Affinity Capture-Western; Biochemical ActivityBioGRID11098060 |12887920 
CASP8BCL2L1-HPRD11733517 
Phenotypic SuppressionBioGRID11832478 
CASP8RB1CASP8 (caspase-8) cleaves RB-1 (hRB) into the p68 form and to a lesser extent the p61 form.BIND15735701 
CASP8MAP4K4-HPRD11002417 
CASP8RIPK2-HPRD9575181 
CASP8PICALM-HPRD10926122 
CASP8HTTHtt interacts with caspase 8.BIND14713958 
CASP8CFLARMRIT-beta-1 interacts with FLICE. This interaction was modelled on a demonstrated interaction between human MRIT-beta-1 and FLICE from an unspecified species.BIND9326610 
Affinity Capture-Western; Reconstituted Complex; Two-hybridBioGRID9208847 |9228018 
|9289491 |9326610 
|11741985 |12215447 
|12887920 
-HPRD9208847 |9289491 
|12215447 
MRIT-alpha-1 interacts with FLICE. This interaction was modelled on a demonstrated interaction between human MRIT-alpha-1 and FLICE from an unspecified species.BIND9326610 
CASP8TNFRSF10BAffinity Capture-Western; Co-purificationBioGRID9325248 |15659383 
-HPRD12218097 
CASP8MAP3K14-HPRD,BioGRID11002417 
CASP8CDH1-HPRD12189238 
CASP8CASP9Biochemical Activity; Phenotypic SuppressionBioGRID8962078 |11832478 
CASP8TRADD-HPRD,BioGRID12887920 
CASP8FADDCASP8 (caspase-8) interacts with FADD.BIND15782135 
-HPRD,BioGRID12107169 
-HPRD11717445 |12107169|12107169 
caspase-8 interacts with FADD.BIND12220669 
CASP8FADDCASP8 (caspase-8) interacts with FADD.BIND15782135 
-HPRD,BioGRID12107169 
-HPRD11717445 |12107169|12107169 
caspase-8 interacts with FADD.BIND12220669 
CASP8SUMO1CASP8 (caspase-8) interacts with SUMO1.BIND15782135 
CASP8RALBP1Affinity Capture-WesternBioGRID12887920 
CASP8FADDCASP8 (caspase-8) interacts with FADD.BIND15782135 
-HPRD,BioGRID12107169 
-HPRD11717445 |12107169|12107169 
caspase-8 interacts with FADD.BIND12220669 
CASP8NR1H4-HPRD,BioGRID11733517 
CASP8DEDD2-HPRD,BioGRID11965497 |12527898|12527898 
CASP8CRADD-HPRD11002417 
CASP8PIAS1CASP8 (caspase-8) interacts with PIAS-1.BIND15782135 
CASP8NOL3ARC interacts with procaspase-8.BIND15383280 
-HPRD,BioGRID9560245 
CASP8FASLGAffinity Capture-Western; Co-purificationBioGRID12887920 |15659383 
CASP8CASP8AP2-HPRD,BioGRID10235259 |11340079 
CASP8FAF1-HPRD12702723 
CASP8TFCP2Two-hybridBioGRID16169070 
CASP8FADDCASP8 (caspase-8) interacts with FADD.BIND15782135 
-HPRD,BioGRID12107169 
-HPRD11717445 |12107169|12107169 
caspase-8 interacts with FADD.BIND12220669 
CASP8NOL3ARC interacts with procaspase-8.BIND15383280 
-HPRD,BioGRID9560245 
CASP8ARHGDIACo-purificationBioGRID15659383 
CASP8CASP2Biochemical ActivityBioGRID8962078 |11832478 
CASP1CARD8-HPRD11821383 
CARD-8 interacts with Casp-1BIND11821383 
CASP1ATXN3Ataxin-3 interacts with caspase 1. This interaction was modeled on a demonstrated interaction between human ataxin-3 and caspase 1 from an unspecified species.BIND9535906 
-HPRD9535906 
CASP1ATXN3Ataxin-3 interacts with caspase 1. This interaction was modeled on a demonstrated interaction between human ataxin-3 and caspase 1 from an unspecified species.BIND9535906 
-HPRD9535906 
CASP1CARD17-HPRD15383541 
CASP1NAAffinity Capture-WesternBioGRID15107016 
CASP1NFE2L2-HPRD,BioGRID10510468 
CASP1NOD2Affinity Capture-WesternBioGRID15107016 
CARD15 (Nod2) interacts with CASP1. This interaction was modelled on a demonstrated interaction between human CARD15 and CASP1 from an unspecified species.BIND15107016 
CASP1PARK2-HPRD12692130 
CASP1CARD8-HPRD11821383 
CARD-8 interacts with Casp-1BIND11821383 
CASP1ARAndrogen Receptor interacts with caspase 1. This interaction was modeled on a demonstrated interaction between human androgen receptor and caspase 1 from an unspecified species.BIND9535906 
CASP1NOD2Affinity Capture-WesternBioGRID15107016 
CARD15 (Nod2) interacts with CASP1. This interaction was modelled on a demonstrated interaction between human CARD15 and CASP1 from an unspecified species.BIND15107016 
CASP1NLRC4-HPRD,BioGRID11472070 
CARD12 (CLAN) interacts with CASP1. This interaction was modelled on a demonstrated interaction between human CARD12 and CASP1 from an unspecified species.BIND15107016 
-HPRD11390368 |11472070|11472070 
CASP1RIPK2-HPRD,BioGRID9705938 
CASP1ATN1Atrophin-1 interacts with caspase 1. This interaction was modeled on a demonstrated interaction between human atrophin-1 and caspase 1 from an unspecified species.BIND9535906 
CASP1COPAffinity Capture-WesternBioGRID11432859 
CASP1EGFR-HPRD,BioGRID11226410 
CASP1NLRC4-HPRD,BioGRID11472070 
CARD12 (CLAN) interacts with CASP1. This interaction was modelled on a demonstrated interaction between human CARD12 and CASP1 from an unspecified species.BIND15107016 
-HPRD11390368 |11472070|11472070 
CASP1NLRP1NALP1 (NAC) interacts with CASP1. This interaction was modelled on a demonstrated interaction between human NALP1 and CASP1 from an unspecified species.BIND15107016 
CASP1BCAP31-HPRD,BioGRID9334338 
CASP1HTTHuntingtin interacts with caspase 1. This interaction was modeled on a demonstrated interaction between human huntingtin and caspase 1 from an unspecified species.BIND9535906 
-HPRD9535906 
CASP1PYCARD-HPRD11967258 |12019269 
|12191486 
CASP1CARD16-HPRD11432859 |11536016 
CASP1HTTHuntingtin interacts with caspase 1. This interaction was modeled on a demonstrated interaction between human huntingtin and caspase 1 from an unspecified species.BIND9535906 
-HPRD9535906 
CASP1NLRC4-HPRD,BioGRID11472070 
CARD12 (CLAN) interacts with CASP1. This interaction was modelled on a demonstrated interaction between human CARD12 and CASP1 from an unspecified species.BIND15107016 
-HPRD11390368 |11472070|11472070 
MSH6MYCAffinity Capture-MSBioGRID17353931 
MSH6MSH2MSH2 interacts with MSH6.BIND15753043 
MSH2 interacts with MSH6.BIND9428522 
-HPRD,BioGRID8942985 |9774676 
MSH6BRCA1BRCA1 associates with MSH6.BIND10783165 |11498787 
-HPRD,BioGRID11498787 
MSH6BARD1Reconstituted ComplexBioGRID11498787 
MSH6NBNCo-purificationBioGRID10783165 
MSH6MSH2MSH2 interacts with MSH6.BIND15753043 
MSH2 interacts with MSH6.BIND9428522 
-HPRD,BioGRID8942985 |9774676 
MSH6RAD50Co-purificationBioGRID10783165 
MSH6PCNA-HPRD11005803 |12171929 
Affinity Capture-MS; Affinity Capture-Western; Far Western; Protein-peptideBioGRID11005803 |11274057 
|12171929 
MSH6 is a PCNA-binding proteinBIND12171929 
MSH6PCNA-HPRD11005803 |12171929 
Affinity Capture-MS; Affinity Capture-Western; Far Western; Protein-peptideBioGRID11005803 |11274057 
|12171929 
MSH6 is a PCNA-binding proteinBIND12171929 
MSH6MUTYHhMYH interacts with hMSH6.BIND11801590 
MSH6ATMCo-purificationBioGRID10783165 
MSH6BRCA1BRCA1 associates with MSH6.BIND10783165 |11498787 
-HPRD,BioGRID11498787 
MSH6MSH2MSH2 interacts with MSH6.BIND15753043 
MSH2 interacts with MSH6.BIND9428522 
-HPRD,BioGRID8942985 |9774676 
MSH6PCNA-HPRD11005803 |12171929 
Affinity Capture-MS; Affinity Capture-Western; Far Western; Protein-peptideBioGRID11005803 |11274057 
|12171929 
MSH6 is a PCNA-binding proteinBIND12171929 
MSH6BLMCo-purificationBioGRID10783165 
MSH6MRE11ACo-purificationBioGRID10783165 
MSH6MLH1Co-purificationBioGRID10783165 
MSH6RFC1Co-purificationBioGRID10783165 
MYCBPAPMYCBP-HPRD,BioGRID12151104 
MYCBPAPCDC2L6Affinity Capture-MSBioGRID17353931 
MYCBPAPPRKAR2A-HPRD12151104 
NOD1RIPK2Nod1 interacts with, and enhances RICK activity.BIND10329646 
-HPRD,BioGRID10329646 
NOD1RIPK2Nod1 interacts with, and enhances RICK activity.BIND10329646 
-HPRD,BioGRID10329646 
NOD1CFLARAffinity Capture-WesternBioGRID10329646 
NOD1CASP2-HPRD,BioGRID10329646 
NOD1CASP9Nod1 interacts with and regulates Caspase-9BIND10329646 
-HPRD,BioGRID10329646 
NOD1CASP9Nod1 interacts with and regulates Caspase-9BIND10329646 
-HPRD,BioGRID10329646 
NOD1CARD6-HPRD,BioGRID12775719 
NOD1NLRC4Affinity Capture-WesternBioGRID15107016 
CARD12 (CLAN) interacts with CARD4 (Nod1).BIND15107016 
NOD1NLRC4Affinity Capture-WesternBioGRID15107016 
CARD12 (CLAN) interacts with CARD4 (Nod1).BIND15107016 
SERPINB9CRMP1Two-hybridBioGRID16169070 
SERPINB9TP53Two-hybridBioGRID16169070 
SERPINB9MED31Two-hybridBioGRID16169070 
SERPINB9IGSF21Two-hybridBioGRID16169070 
SERPINB9C14orf1Two-hybridBioGRID16169070 
SERPINB9GZMB-HPRD,BioGRID8910377 
SERPINB9GDF9Two-hybridBioGRID16169070 
SERPINB9CCDC90BTwo-hybridBioGRID16169070 
SERPINB9TLE1Two-hybridBioGRID16169070 
SERPINB9PRPF40ATwo-hybridBioGRID16169070 
SERPINB9UBR1Two-hybridBioGRID16169070 
SERPINB9XRCC6Two-hybridBioGRID16169070 
SERPINB9C1orf103Two-hybridBioGRID16169070 
SERPINB9TUBB2ATwo-hybridBioGRID16169070 
SERPINB9C7orf64Two-hybridBioGRID16169070 
SERPINB9UNC119Two-hybridBioGRID16169070 
SERPINB9ZHX1Two-hybridBioGRID16169070 
SERPINB9PLEKHM1Two-hybridBioGRID16169070 
SERPINB9ECH1Two-hybridBioGRID16169070 
SERPINB9BRD7Two-hybridBioGRID16169070 
SERPINB9COPS6Two-hybridBioGRID16169070 
SERPINB9GAPDHTwo-hybridBioGRID16169070 
SERPINB9EEF1A1Two-hybridBioGRID16169070 
SERPINB9SETDB1Two-hybridBioGRID16169070 
SERPINB9GBP2Two-hybridBioGRID16169070 
HEATR2ZBTB16Two-hybridBioGRID16169070 
HEATR2BRF2Affinity Capture-MSBioGRID17353931 
HEATR2ILKAffinity Capture-MSBioGRID17353931 
HEATR2GSTK1Affinity Capture-MSBioGRID17353931 
HEATR2PTP4A3Affinity Capture-MSBioGRID17353931 
HEATR2CIAO1Affinity Capture-MSBioGRID17353931 
HEATR2TSC22D1Affinity Capture-MSBioGRID17353931 
HEATR2PNKPAffinity Capture-MSBioGRID17353931 
HEATR2PGRMC1Affinity Capture-MSBioGRID17353931 
HEATR2MAGED1Affinity Capture-MSBioGRID17353931 
HEATR2PHLDA3Affinity Capture-MSBioGRID17353931 
HEATR2MAGEA6Affinity Capture-MSBioGRID17353931 
HEATR2FEZ1Two-hybridBioGRID16169070 
VDAC3DDX24Two-hybridBioGRID16169070 
SMC3MXD4Reconstituted Complex; Two-hybridBioGRID9528857 
SMC3MXI1Reconstituted Complex; Two-hybridBioGRID9528857 
SMC3TUBBAffinity Capture-WesternBioGRID11590136 
SMC3NEK6Affinity Capture-MSBioGRID17353931 
SMC3NUMA1Affinity Capture-WesternBioGRID11590136 
SMC3MXD3Reconstituted Complex; Two-hybridBioGRID9528857 
SMC3CDK4Affinity Capture-MSBioGRID17353931 
SMC3SYCP3Affinity Capture-WesternBioGRID12759374 
SMC3MXD1Reconstituted Complex; Two-hybridBioGRID9528857 
SMC3SMARCA5Co-purificationBioGRID12198550 
SMC3SMC1B-HPRD11564881 |12759374 
|15125634 
SMC3MAGED1Affinity Capture-MSBioGRID17353931 
SMC3HDAC2Co-purificationBioGRID12198550 
SMC3KIFAP3-HPRD,BioGRID9506951 
SMC3REC8Affinity Capture-WesternBioGRID12759374 
SMC3STAG1Co-purificationBioGRID11076961 
SMC1ANUMA1-HPRD,BioGRID11590136 
SMC1ACDK4Affinity Capture-MSBioGRID17353931 
SMC1ASYCP3Affinity Capture-WesternBioGRID12759374 
SMC1AMSH2-HPRD14657349 
SMC1AMDC1-HPRD12607005 
SMC1ANDC80-HPRD,BioGRID9295362 
SMC1ABRCA1-HPRD11877377 
SMC1AREC8Affinity Capture-WesternBioGRID12759374 
SMC1AATMAffinity Capture-Western; Reconstituted ComplexBioGRID11877376 
SMC1ASTAG1Co-purificationBioGRID11076961 
SMC1ACHTF18Affinity Capture-WesternBioGRID12930902 
SMC1ASTYXL1Affinity Capture-MSBioGRID17353931 
SMC1ARAD21Affinity Capture-WesternBioGRID11590136 
SMC1ASMARCA5Co-purificationBioGRID12198550 
SMC1ABLM-HPRD11877377 
SLC25A22PSMD13Affinity Capture-MSBioGRID17353931 
SLC25A22TSC22D1Affinity Capture-MSBioGRID17353931 
USP9XRELB-HPRD14743216 
USP9XCTNNB1-HPRD,BioGRID10620020 
USP9XMLLT4-HPRD,BioGRID9722616 
USP9XNFKB2-HPRD14743216 
USP9XNEK6Affinity Capture-MSBioGRID17353931 
CTNNBIP1GLB1Affinity Capture-MSBioGRID17353931 
CTNNBIP1JUPAffinity Capture-MS; Two-hybridBioGRID16189514 |17353931 
CTNNBIP1BEND5Two-hybridBioGRID16189514 
CTNNBIP1PPP2R1AAffinity Capture-MSBioGRID17353931 
CTNNBIP1CPVLAffinity Capture-MSBioGRID17353931 
CTNNBIP1GOT2Affinity Capture-MSBioGRID17353931 
CTNNBIP1PNMA2Affinity Capture-MSBioGRID17353931 
CTNNBIP1CTNNB1-HPRD,BioGRID10898789 
CTNNBIP1CTSAAffinity Capture-MSBioGRID17353931 
CTNNBIP1RPA3Affinity Capture-MSBioGRID17353931 
CTNNBIP1NACAP1Affinity Capture-MSBioGRID17353931 


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