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Protein-protein interaction for CUL3
 Nodes,
degree=1 |
 Nodes,
degree=2 |
Protein-protein interaction data for gene CUL3
| Degree = 1 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| CUL3 | CCND1 | - | HPRD | 10500095 |
| CUL3 | RBX1 | - | HPRD | 11311237 |
| Affinity Capture-MS | BioGRID | 12481031 | ||
| CUL3 | CCNE1 | - | HPRD,BioGRID | 10500095 |
| CUL3 | CAND1 | Affinity Capture-MS; Affinity Capture-Western | BioGRID | 12609982 |
| CUL3 | GPS1 | - | HPRD | 11337588 |
| CUL3 | NEDD8 | - | HPRD | 10500095 |
| Degree = 2 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| CCND1 | NCOA3 | - | HPRD,BioGRID | 9832502 |
| AIB1 interacts with cyclin D1 promoter. | BIND | 15808510 | ||
| CCND1 | POLR2A | Pol II interacts with cyclin D1 promoter. | BIND | 15808510 |
| CCND1 | HDAC3 | Affinity Capture-Western | BioGRID | 12048199 |15558026 |
| CCND1 | NEUROD1 | Affinity Capture-Western; Phenotypic Suppression | BioGRID | 11788592 |
| CCND1 | CHUK | IKK-alpha interacts with cyclin D1 promoter. | BIND | 15808510 |
| CCND1 | CREBBP | CBP interacts with cyclin D1 promoter. | BIND | 15808510 |
| CCND1 | ESR1 | - | HPRD,BioGRID | 9039267 |
| ER-alpha interacts with cyclin D1 promoter. | BIND | 15808510 | ||
| CCND1 | CDKN1B | in vitro; Reconstituted Complex | BioGRID | 10908655 |11360184 |
| p27 interacts with cyclin D. | BIND | 9632134 | ||
| - | HPRD | 7478582 |10908655 | ||
| CCND1 | CTNNB1 | CTNNB1 (beta-catenin) interacts with the CCND1 promoter. | BIND | 15592430 |
| - | HPRD | 11836555 | ||
| CCND1 | CDK4 | - | HPRD | 9150368 |9837900 |
| CDK4 interacts with Cyclin D1. This interaction was modelled on a demonstrated interaction between human CDK4 and Cyclin D1 from an unspecified species. | BIND | 9228064 | ||
| CCND1 (cyclin D1) interacts with CDK4. | BIND | 8662825 | ||
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 8259215 |9837900 |10580009 |11360184 | ||
| CCND1 | CDK6 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 10580009 |11360184 |
| - | HPRD | 11739795 | ||
| CCND1 (cyclin D1) interacts with CDK6. | BIND | 12867429 | ||
| CCND1 | BRCA1 | - | HPRD,BioGRID | 9244350 |
| BRCA1 associates with Cyclin D1 | BIND | 9244350 | ||
| CCND1 | THRB | Affinity Capture-Western; Reconstituted Complex | BioGRID | 12048199 |
| CCND1 | CDK6 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 10580009 |11360184 |
| - | HPRD | 11739795 | ||
| CCND1 (cyclin D1) interacts with CDK6. | BIND | 12867429 | ||
| CCND1 | NCOA3 | - | HPRD,BioGRID | 9832502 |
| AIB1 interacts with cyclin D1 promoter. | BIND | 15808510 | ||
| CCND1 | CDKN1C | Reconstituted Complex | BioGRID | 10764802 |
| CCND1 | KLF6 | KLF6 interacts with Cyclin D1. | BIND | 15172998 |
| CCND1 | ERCC3 | TFIIH interacts with Cyclin D1 promoter. | BIND | 15893730 |
| CCND1 | CDKN1A | - | HPRD,BioGRID | 7478582 |8657154 |
| p21 interacts with cyclin D. | BIND | 9632134 | ||
| Cyclin D1 interacts with p21. | BIND | 8999999 | ||
| CDKN1A (p21) interacts with CCND1 (cyclin D1). | BIND | 8662825 | ||
| CCND1 | TAF1 | TAFII250 interacts with Cyclin D1. This interaction was modelled on a demonstrated interaction between TAFII250 from human and Cyclin D1 from mouse. | BIND | 11126356 |
| - | HPRD,BioGRID | 9926939 |11126356 | ||
| CCND1 | TSC2 | Affinity Capture-Western | BioGRID | 16357142 |
| CCND1 | TAF1 | TAFII250 interacts with Cyclin D1. This interaction was modelled on a demonstrated interaction between TAFII250 from human and Cyclin D1 from mouse. | BIND | 11126356 |
| - | HPRD,BioGRID | 9926939 |11126356 | ||
| CCND1 | RFC1 | - | HPRD,BioGRID | 10353443 |
| CCND1 | STAT3 | An unspecified isoform of STAT3 binds to Cyclin D1 promoter. | BIND | 15950906 |
| - | HPRD,BioGRID | 11279133 | ||
| CCND1 | CDKN1A | - | HPRD,BioGRID | 7478582 |8657154 |
| p21 interacts with cyclin D. | BIND | 9632134 | ||
| Cyclin D1 interacts with p21. | BIND | 8999999 | ||
| CDKN1A (p21) interacts with CCND1 (cyclin D1). | BIND | 8662825 | ||
| CCND1 | CCNDBP1 | - | HPRD,BioGRID | 10801854 |
| CCND1 | CALM1 | - | HPRD | 9837900 |
| CCND1 | CDKN1B | in vitro; Reconstituted Complex | BioGRID | 10908655 |11360184 |
| p27 interacts with cyclin D. | BIND | 9632134 | ||
| - | HPRD | 7478582 |10908655 | ||
| CCND1 | KAT2B | - | HPRD,BioGRID | 10318892 |
| CCND1 | MCM10 | - | HPRD | 15232106 |
| CCND1 | CDK6 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 10580009 |11360184 |
| - | HPRD | 11739795 | ||
| CCND1 (cyclin D1) interacts with CDK6. | BIND | 12867429 | ||
| CCND1 | CDKN2A | Reconstituted Complex | BioGRID | 10580009 |
| CCND1 | RB1 | Rb interacts with Cyclin D1. This interaction was modelled on a demonstrated interaction between Cyclin D1 from mouse and Rb from human. | BIND | 11126356 |
| - | HPRD,BioGRID | 8490963 | ||
| CCND1 | PCNA | Reconstituted Complex | BioGRID | 7908906 |
| CCND1 | NPDC1 | - | HPRD,BioGRID | 11042687 |
| CCND1 | EP300 | - | HPRD,BioGRID | 11788592 |
| CCND1 | IFI27 | - | HPRD | 9837900 |
| CCND1 | STAT3 | An unspecified isoform of STAT3 binds to Cyclin D1 promoter. | BIND | 15950906 |
| - | HPRD,BioGRID | 11279133 | ||
| CCND1 | AKAP8 | - | HPRD,BioGRID | 14641107 |
| CCND1 | CDKN1A | - | HPRD,BioGRID | 7478582 |8657154 |
| p21 interacts with cyclin D. | BIND | 9632134 | ||
| Cyclin D1 interacts with p21. | BIND | 8999999 | ||
| CDKN1A (p21) interacts with CCND1 (cyclin D1). | BIND | 8662825 | ||
| CCND1 | BRCA1 | - | HPRD,BioGRID | 9244350 |
| BRCA1 associates with Cyclin D1 | BIND | 9244350 | ||
| CCND1 | CTNNB1 | CTNNB1 (beta-catenin) interacts with the CCND1 promoter. | BIND | 15592430 |
| - | HPRD | 11836555 | ||
| CCND1 | CDKN1A | - | HPRD,BioGRID | 7478582 |8657154 |
| p21 interacts with cyclin D. | BIND | 9632134 | ||
| Cyclin D1 interacts with p21. | BIND | 8999999 | ||
| CDKN1A (p21) interacts with CCND1 (cyclin D1). | BIND | 8662825 | ||
| CCND1 | DMTF1 | - | HPRD | 8887674 |
| CCND1 | RB1 | Rb interacts with Cyclin D1. This interaction was modelled on a demonstrated interaction between Cyclin D1 from mouse and Rb from human. | BIND | 11126356 |
| - | HPRD,BioGRID | 8490963 | ||
| CCND1 | CDKN1B | in vitro; Reconstituted Complex | BioGRID | 10908655 |11360184 |
| p27 interacts with cyclin D. | BIND | 9632134 | ||
| - | HPRD | 7478582 |10908655 | ||
| CCND1 | CREB1 | CREB interacts with CRE. | BIND | 15897899 |
| CCND1 | XPO1 | Reconstituted Complex | BioGRID | 12529437 |
| CCND1 | FOXO4 | MLLT7 (FOXO4) interacts with the CCND1 (Cyclin D1) promoter. This interaction was modelled on a demonstrated interaction between MLLT7 and CCND1 both from unspecified species. | BIND | 15688030 |
| CCND1 | MYBL2 | - | HPRD | 10645009 |
| CCND1 | CDK4 | - | HPRD | 9150368 |9837900 |
| CDK4 interacts with Cyclin D1. This interaction was modelled on a demonstrated interaction between human CDK4 and Cyclin D1 from an unspecified species. | BIND | 9228064 | ||
| CCND1 (cyclin D1) interacts with CDK4. | BIND | 8662825 | ||
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 8259215 |9837900 |10580009 |11360184 | ||
| CCND1 | THRA | - | HPRD,BioGRID | 12048199 |
| CCND1 | CDK4 | - | HPRD | 9150368 |9837900 |
| CDK4 interacts with Cyclin D1. This interaction was modelled on a demonstrated interaction between human CDK4 and Cyclin D1 from an unspecified species. | BIND | 9228064 | ||
| CCND1 (cyclin D1) interacts with CDK4. | BIND | 8662825 | ||
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 8259215 |9837900 |10580009 |11360184 | ||
| CCND1 | NCOA1 | - | HPRD,BioGRID | 9832502 |
| CCND1 | PIN1 | PIN1 interacts with Cyclin D1. This interaction was modelled on a demonstrated interaction between human PIN1 and Cyclin D1 from an unspecified species. | BIND | 11805292 |
| CCND1 | CDK4 | - | HPRD | 9150368 |9837900 |
| CDK4 interacts with Cyclin D1. This interaction was modelled on a demonstrated interaction between human CDK4 and Cyclin D1 from an unspecified species. | BIND | 9228064 | ||
| CCND1 (cyclin D1) interacts with CDK4. | BIND | 8662825 | ||
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 8259215 |9837900 |10580009 |11360184 | ||
| CCND1 | ESR1 | - | HPRD,BioGRID | 9039267 |
| ER-alpha interacts with cyclin D1 promoter. | BIND | 15808510 | ||
| CCND1 | HERC5 | - | HPRD,BioGRID | 10581175 |
| CCND1 | RBL1 | - | HPRD,BioGRID | 8643455 |
| CCND1 | AR | - | HPRD,BioGRID | 10344732 |
| CCND1 | RELA | RELA (NF-kappaB p65 subunit) interacts with the CCND1 (Cyclin D1) promoter. | BIND | 15652748 |
| CCND1 | CDKN2D | - | HPRD | 7739547 |
| CCND1 | EGFR | An unspecified isoform of EGFR binds to Cyclin D1 promoter. | BIND | 15950906 |
| RBX1 | CUL7 | Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex | BioGRID | 12481031 |
| RBX1 | VHL | Affinity Capture-MS | BioGRID | 17353931 |
| RBX1 | HSPA8 | Affinity Capture-MS | BioGRID | 12481031 |
| RBX1 | CCND3 | Affinity Capture-Western | BioGRID | 11311237 |
| RBX1 | CUL5 | Rbx1 interacts with Cul5. | BIND | 14564014 |
| RBX1 | HSPA1A | Affinity Capture-MS | BioGRID | 12481031 |
| RBX1 | SKP1 | Affinity Capture-Western | BioGRID | 12628165 |
| RBX1 | CUL4A | ROC1 interacts with Cul4A. | BIND | 15448697 |
| Affinity Capture-MS | BioGRID | 12481031 | ||
| RBX1 | CUL2 | Affinity Capture-MS | BioGRID | 12481031 |
| RBX1 | ACTG1 | Affinity Capture-MS | BioGRID | 12481031 |
| RBX1 | COPS6 | - | HPRD | 11337588 |
| RBX1 | CUL4A | ROC1 interacts with Cul4A. | BIND | 15448697 |
| Affinity Capture-MS | BioGRID | 12481031 | ||
| RBX1 | RFWD2 | Affinity Capture-Western | BioGRID | 14739464 |
| RBX1 | DET1 | Affinity Capture-Western | BioGRID | 14739464 |
| RBX1 | FBXO22 | Affinity Capture-MS | BioGRID | 12481031 |
| RBX1 | CUL1 | CUL1 interacts with ROC1. | BIND | 11956208 |
| - | HPRD,BioGRID | 11961546 | ||
| Rbx1 interacts with Cul1 [411-776] to form part of the Cul1-Rbx1-Skp1-F Boxskp2 Scf Ubiquitin Ligase complex. | BIND | 11961546 | ||
| RBX1 | CDC34 | Reconstituted Complex | BioGRID | 11675391 |
| RBX1 | CUL1 | CUL1 interacts with ROC1. | BIND | 11956208 |
| - | HPRD,BioGRID | 11961546 | ||
| Rbx1 interacts with Cul1 [411-776] to form part of the Cul1-Rbx1-Skp1-F Boxskp2 Scf Ubiquitin Ligase complex. | BIND | 11961546 | ||
| RBX1 | CUL1 | CUL1 interacts with ROC1. | BIND | 11956208 |
| - | HPRD,BioGRID | 11961546 | ||
| Rbx1 interacts with Cul1 [411-776] to form part of the Cul1-Rbx1-Skp1-F Boxskp2 Scf Ubiquitin Ligase complex. | BIND | 11961546 | ||
| RBX1 | CUL4B | Affinity Capture-MS | BioGRID | 12481031 |
| RBX1 | FBXO3 | Affinity Capture-MS | BioGRID | 12481031 |
| RBX1 | TUBA1B | Affinity Capture-MS | BioGRID | 12481031 |
| RBX1 | CCND2 | Affinity Capture-Western | BioGRID | 11311237 |
| RBX1 | FBXW8 | Affinity Capture-Western | BioGRID | 12481031 |
| RBX1 | FBXO18 | - | HPRD,BioGRID | 11956208 |
| CCNE1 | CDKN1B | p27 interacts with cyclin E. | BIND | 9632134 |
| p27 interacts with Cyc E. | BIND | 15469821 | ||
| Affinity Capture-Western | BioGRID | 9891079 |12529437 | ||
| CCNE1 | SF3B1 | Affinity Capture-Western | BioGRID | 9891079 |
| CCNE1 | CCT4 | - | HPRD,BioGRID | 9819444 |
| CCNE1 | SMARCC1 | - | HPRD,BioGRID | 9891079 |
| CCNE1 | FBXW7 | Phosphorylated cycE interacts with Fbw7. This interaction was modeled on a demonstrated interaction between cycE from human and Fbw7 from an unspecified species. | BIND | 14739463 |
| - | HPRD,BioGRID | 11533444 |11565033 |14536078 | ||
| hCDC4 interacts with cyclin E. This interaction was modelled on a demonstrated interaction between human CDC4 and cyclin E from an unspecified species. | BIND | 14999283 | ||
| CCNE1 | CDC25A | - | HPRD,BioGRID | 8617791 |
| CCNE1 | SMARCB1 | Affinity Capture-Western | BioGRID | 9891079 |
| CCNE1 | COIL | - | HPRD,BioGRID | 10751146 |
| CCNE1 | GSK3B | Biochemical Activity | BioGRID | 14536078 |
| CCNE1 | HERC5 | - | HPRD,BioGRID | 10581175 |
| CCNE1 | AR | - | HPRD,BioGRID | 10953010 |
| CCNE1 | CDKN1A | p21 interacts with cyclin E. | BIND | 9632134 |
| Affinity Capture-Western | BioGRID | 12839982 | ||
| CDKN1A (p21) interacts with CCNE1 (cyclin E). | BIND | 8662825 | ||
| CCNE1 | FBXW7 | Phosphorylated cycE interacts with Fbw7. This interaction was modeled on a demonstrated interaction between cycE from human and Fbw7 from an unspecified species. | BIND | 14739463 |
| - | HPRD,BioGRID | 11533444 |11565033 |14536078 | ||
| hCDC4 interacts with cyclin E. This interaction was modelled on a demonstrated interaction between human CDC4 and cyclin E from an unspecified species. | BIND | 14999283 | ||
| CCNE1 | SMARCA4 | - | HPRD,BioGRID | 9891079 |
| CCNE1 | REL | - | HPRD | 9731206 |
| CCNE1 | RBL2 | - | HPRD,BioGRID | 8253383 |
| CCNE1 | FBXW7 | Phosphorylated cycE interacts with Fbw7. This interaction was modeled on a demonstrated interaction between cycE from human and Fbw7 from an unspecified species. | BIND | 14739463 |
| - | HPRD,BioGRID | 11533444 |11565033 |14536078 | ||
| hCDC4 interacts with cyclin E. This interaction was modelled on a demonstrated interaction between human CDC4 and cyclin E from an unspecified species. | BIND | 14999283 | ||
| CCNE1 | SMARCA2 | Affinity Capture-Western | BioGRID | 9891079 |
| CCNE1 | RRN3 | Reconstituted Complex | BioGRID | 15004009 |
| CCNE1 | RBL1 | - | HPRD | 8230483 |
| Affinity Capture-Western | BioGRID | 9891079 | ||
| CCNE1 | CDKN1B | p27 interacts with cyclin E. | BIND | 9632134 |
| p27 interacts with Cyc E. | BIND | 15469821 | ||
| Affinity Capture-Western | BioGRID | 9891079 |12529437 | ||
| CCNE1 | BRCA1 | Affinity Capture-Western | BioGRID | 17525332 |
| CCNE1 | E2F4 | Affinity Capture-Western | BioGRID | 9891079 |
| CCNE1 | RBL1 | - | HPRD | 8230483 |
| Affinity Capture-Western | BioGRID | 9891079 | ||
| CCNE1 | CDK2 | - | HPRD,BioGRID | 1388288 |
| CCNE1 | CDK3 | - | HPRD,BioGRID | 11733001 |
| CCNE1 | CDKN1A | p21 interacts with cyclin E. | BIND | 9632134 |
| Affinity Capture-Western | BioGRID | 12839982 | ||
| CDKN1A (p21) interacts with CCNE1 (cyclin E). | BIND | 8662825 | ||
| CCNE1 | CDKN1B | p27 interacts with cyclin E. | BIND | 9632134 |
| p27 interacts with Cyc E. | BIND | 15469821 | ||
| Affinity Capture-Western | BioGRID | 9891079 |12529437 | ||
| CCNE1 | CDKN1A | p21 interacts with cyclin E. | BIND | 9632134 |
| Affinity Capture-Western | BioGRID | 12839982 | ||
| CDKN1A (p21) interacts with CCNE1 (cyclin E). | BIND | 8662825 | ||
| CCNE1 | PARK2 | Affinity Capture-Western | BioGRID | 12628165 |
| CCNE1 | CABLES1 | - | HPRD | 11733001 |
| CCNE1 | SKP2 | - | HPRD,BioGRID | 11237742 |
| CCNE1 | CDC2 | - | HPRD,BioGRID | 1388288 |
| CAND1 | CUL4A | Affinity Capture-MS; Affinity Capture-Western | BioGRID | 12609982 |
| CAND1 | CUL2 | Affinity Capture-MS; Affinity Capture-Western | BioGRID | 12609982 |
| CAND1 | CUL4B | - | HPRD,BioGRID | 12609982 |
| CAND1 | CUL1 | Affinity Capture-MS; Affinity Capture-Western | BioGRID | 12609982 |
| GPS1 | CUL2 | - | HPRD | 11337588 |
| GPS1 | COPS3 | - | HPRD | 11114242 |
| GPS1 | SKP1 | - | HPRD | 11337588 |
| GPS1 | COPS2 | CSN1 interacts with CSN2. | BIND | 12615944 |
| - | HPRD | 11114242 | ||
| GPS1 | SKP2 | - | HPRD | 11337588 |
| GPS1 | COPS4 | - | HPRD | 9707402 |14647295 |
| CSN1 interacts with CSN4. | BIND | 12615944 | ||
| - | HPRD | 11114242 | ||
| GPS1 | COPS2 | CSN1 interacts with CSN2. | BIND | 12615944 |
| - | HPRD | 11114242 | ||
| GPS1 | COPS4 | - | HPRD | 9707402 |14647295 |
| CSN1 interacts with CSN4. | BIND | 12615944 | ||
| - | HPRD | 11114242 | ||
| GPS1 | COPS4 | - | HPRD | 9707402 |14647295 |
| CSN1 interacts with CSN4. | BIND | 12615944 | ||
| - | HPRD | 11114242 | ||
| GPS1 | COPS8 | Co-purification | BioGRID | 9707402 |
| - | HPRD | 11337588 | ||
| GPS1 | CUL1 | - | HPRD | 11337588 |
| GPS1 | WDR8 | Affinity Capture-MS | BioGRID | 17353931 |
| GPS1 | ITPK1 | - | HPRD | 12324474 |
| GPS1 | COPS8 | Co-purification | BioGRID | 9707402 |
| - | HPRD | 11337588 | ||
| NEDD8 | UBE2K | - | HPRD | 9857030 |
| NEDD8 | UBA2 | - | HPRD,BioGRID | 10217437 |
| NEDD8 | CDC34 | - | HPRD | 11675391 |
| NEDD8 | UBE2M | - | HPRD,BioGRID | 10828074 |
| NEDD8 | VHL | Affinity Capture-MS | BioGRID | 17353931 |
| NEDD8 | AHR | - | HPRD,BioGRID | 12215427 |
| NEDD8 | MAGED1 | Affinity Capture-MS | BioGRID | 17353931 |
| NEDD8 | CDK2 | Affinity Capture-MS | BioGRID | 17353931 |
| NEDD8 | CUL4A | Affinity Capture-MS | BioGRID | 12481031 |
| NEDD8 | NUB1 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 11585840 |14757770 |
| - | HPRD | 11259415 | ||
| NEDD8 | UBA3 | - | HPRD,BioGRID | 10207026 |
| NEDD8 | NUB1 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 11585840 |14757770 |
| - | HPRD | 11259415 | ||
| NEDD8 | FBXO4 | Affinity Capture-MS | BioGRID | 17353931 |
| NEDD8 | UCHL1 | Two-hybrid | BioGRID | 16169070 |
| NEDD8 | TFE3 | Affinity Capture-MS | BioGRID | 17353931 |
| NEDD8 | UCHL3 | - | HPRD,BioGRID | 9790970 |
| NEDD8 | PSMD4 | - | HPRD,BioGRID | 11585840 |
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