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Protein-protein interaction for SHANK3
 Nodes,
degree=1 |
 Nodes,
degree=2 |
Protein-protein interaction data for gene SHANK3
| Degree = 1 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| SHANK3 | DLGAP3 | Two-hybrid | BioGRID | 10527873 |
| SHANK3 | SPTAN1 | Two-hybrid | BioGRID | 11509555 |
| SHANK3 | DLGAP4 | Two-hybrid | BioGRID | 10527873 |
| SHANK3 | DLGAP1 | Two-hybrid | BioGRID | 10527873 |
| SHANK3 | DLGAP2 | Two-hybrid | BioGRID | 10527873 |
| SHANK3 | ARHGEF7 | Affinity Capture-Western; Two-hybrid | BioGRID | 12626503 |
| Degree = 2 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| DLGAP3 | DLG4 | Two-hybrid | BioGRID | 9115257 |
| DLGAP3 | SHANK2 | Two-hybrid | BioGRID | 10527873 |
| SPTAN1 | MAP3K7IP2 | - | HPRD | 14743216 |
| SPTAN1 | FANCG | Co-purification | BioGRID | 11401546 |
| SPTAN1 | SHANK1 | - | HPRD,BioGRID | 11509555 |
| SPTAN1 | GRIA2 | Affinity Capture-Western; Far Western | BioGRID | 10576550 |
| SPTAN1 | NEFL | - | HPRD,BioGRID | 1902666 |3121319 |
| SPTAN1 | PRKCB | - | HPRD | 8163551 |
| SPTAN1 | CTNNA1 | - | HPRD | 11069925 |
| SPTAN1 | EPB42 | - | HPRD,BioGRID | 12049649 |
| SPTAN1 | TSSC4 | Two-hybrid | BioGRID | 16169070 |
| SPTAN1 | ABL1 | Reconstituted Complex; Two-hybrid | BioGRID | 9593709 |
| SPTAN1 | ACP1 | - | HPRD | 11971983 |
| SPTAN1 | SLC9A2 | - | HPRD | 10579058 |
| SPTAN1 | PDE4D | PDE4D4 interacts with Fodrin. This interaction was modelled on a demonstrated interaction between human PDE4D4 and Fodrin from an unspecified species. | BIND | 10571082 |
| SPTAN1 | DDX24 | Two-hybrid | BioGRID | 16169070 |
| SPTAN1 | GRIN1 | - | HPRD | 9670010 |10862698 |
| SPTAN1 | TES | AlphaII-spectrin interacts with Tes. | BIND | 15656790 |
| SPTAN1 | SPTB | - | HPRD,BioGRID | 9890967 |
| SPTAN1 | GAP43 | - | HPRD | 10521589 |
| SPTAN1 | CAPN3 | - | HPRD | 9642272 |
| SPTAN1 | FANCC | Affinity Capture-Western; Co-purification | BioGRID | 10551855 |11401546 |
| SPTAN1 | SYN1 | - | HPRD | 1905928 |
| SPTAN1 | EVL | AlphaII-spectrin interacts with EVL. | BIND | 15656790 |
| SPTAN1 | DISC1 | An unspecified isoform of DISC1 interacts with SPTAN1. | BIND | 14623284 |
| SPTAN1 | ACTB | - | HPRD | 9209005 |
| SPTAN1 | PTP4A1 | - | HPRD | 11971983 |
| SPTAN1 | TANC1 | - | HPRD | 15673434 |
| SPTAN1 | EPB41 | Reconstituted Complex | BioGRID | 12044158 |
| - | HPRD | 12049649 | ||
| SPTAN1 | ADD2 | - | HPRD | 7642559 |
| SPTAN1 | PTOV1 | Two-hybrid | BioGRID | 16169070 |
| SPTAN1 | ADD1 | - | HPRD,BioGRID | 8663089 |
| SPTAN1 | ERCC4 | Affinity Capture-Western | BioGRID | 12571280 |
| SPTAN1 | FANCA | Affinity Capture-Western; Co-purification | BioGRID | 10551855 |11401546 |12571280 |
| SPTAN1 | DES | - | HPRD,BioGRID | 2939097 |
| SPTAN1 | EPB41 | Reconstituted Complex | BioGRID | 12044158 |
| - | HPRD | 12049649 | ||
| SPTAN1 | ANK1 | - | HPRD | 492324 |2141335 |2970468 |2971657 |
| SPTAN1 | PIN4 | Two-hybrid | BioGRID | 16169070 |
| SPTAN1 | PLEC1 | - | HPRD,BioGRID | 3027087 |
| DLGAP4 | SORBS2 | - | HPRD,BioGRID | 10521485 |
| DLGAP4 | GRIN2D | - | HPRD | 10862698 |
| DLGAP4 | SHANK2 | Two-hybrid | BioGRID | 10527873 |
| DLGAP4 | EXOC4 | - | HPRD | 12675619 |
| DLGAP4 | GRIN1 | - | HPRD | 10862698 |
| DLGAP4 | DLG4 | Two-hybrid | BioGRID | 9115257 |
| DLGAP4 | SYNGAP1 | - | HPRD | 9581761 |9620694 |11487731 |
| DLGAP4 | DLG3 | - | HPRD | 9115257 |
| DLGAP4 | UBC | Two-hybrid | BioGRID | 16169070 |
| DLGAP4 | DLG1 | - | HPRD | 9115257 |
| DLGAP4 | PPP1R1B | Two-hybrid | BioGRID | 16169070 |
| DLGAP1 | DYNLL2 | DAP-1 interacts with DLC-2. | BIND | 11122378 |
| - | HPRD,BioGRID | 10844022 | ||
| DLGAP1 | GRIN2A | - | HPRD,BioGRID | 9286858 |
| DLGAP1 | CTNNB1 | Affinity Capture-Western | BioGRID | 9286858 |
| DLGAP1 | SHANK2 | - | HPRD,BioGRID | 10527873 |
| DLGAP1 | DLG4 | Affinity Capture-Western; Co-fractionation; Far Western; Reconstituted Complex; Two-hybrid | BioGRID | 9024696 |9115257 |9286858 |10527873 |10844022 |11060025 |
| - | HPRD | 9024696 |9286858 | ||
| PSD-95 interacts with DAP-1alpha. | BIND | 9286858 | ||
| DLGAP1 | DLG1 | - | HPRD,BioGRID | 9286858 |
| hDLG interacts with DAP-1alpha. | BIND | 9286858 | ||
| DLGAP1 (GKAP) interacts with DLG1 (SAP97). | BIND | 15729360 | ||
| hDLG interacts with DAP-1beta. | BIND | 9286858 | ||
| DLGAP1 | DLG1 | - | HPRD,BioGRID | 9286858 |
| hDLG interacts with DAP-1alpha. | BIND | 9286858 | ||
| DLGAP1 (GKAP) interacts with DLG1 (SAP97). | BIND | 15729360 | ||
| hDLG interacts with DAP-1beta. | BIND | 9286858 | ||
| DLGAP1 | MYO5A | Reconstituted Complex | BioGRID | 10844022 |
| DLGAP1 | APC | - | HPRD,BioGRID | 9286858 |
| DLGAP1 | KCNA4 | - | HPRD | 9024696 |
| DLGAP1 | DLG4 | Affinity Capture-Western; Co-fractionation; Far Western; Reconstituted Complex; Two-hybrid | BioGRID | 9024696 |9115257 |9286858 |10527873 |10844022 |11060025 |
| - | HPRD | 9024696 |9286858 | ||
| PSD-95 interacts with DAP-1alpha. | BIND | 9286858 | ||
| DLGAP1 | DLG2 | DAP-1 interacts with Chapsyn-110. | BIND | 11122378 |
| Affinity Capture-Western | BioGRID | 10844022 | ||
| DLGAP1 | DLG1 | - | HPRD,BioGRID | 9286858 |
| hDLG interacts with DAP-1alpha. | BIND | 9286858 | ||
| DLGAP1 (GKAP) interacts with DLG1 (SAP97). | BIND | 15729360 | ||
| hDLG interacts with DAP-1beta. | BIND | 9286858 | ||
| DLGAP1 | SHANK1 | Co-crystal Structure | BioGRID | 12954649 |
| DLGAP1 | DYNLL1 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 10844022 |
| DAP-1 interacts with DLC-1. | BIND | 11122378 | ||
| DLC8 interacts with GKAP. This interaction was modeled on a demonstrated interaction between DLC8 from an unspecified species and human GKAP. | BIND | 11148209 | ||
| DLGAP1 | DYNLL1 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 10844022 |
| DAP-1 interacts with DLC-1. | BIND | 11122378 | ||
| DLC8 interacts with GKAP. This interaction was modeled on a demonstrated interaction between DLC8 from an unspecified species and human GKAP. | BIND | 11148209 | ||
| DLGAP1 | DLG4 | Affinity Capture-Western; Co-fractionation; Far Western; Reconstituted Complex; Two-hybrid | BioGRID | 9024696 |9115257 |9286858 |10527873 |10844022 |11060025 |
| - | HPRD | 9024696 |9286858 | ||
| PSD-95 interacts with DAP-1alpha. | BIND | 9286858 | ||
| DLGAP1 | DLG2 | DAP-1 interacts with Chapsyn-110. | BIND | 11122378 |
| Affinity Capture-Western | BioGRID | 10844022 | ||
| DLGAP1 | DLG1 | - | HPRD,BioGRID | 9286858 |
| hDLG interacts with DAP-1alpha. | BIND | 9286858 | ||
| DLGAP1 (GKAP) interacts with DLG1 (SAP97). | BIND | 15729360 | ||
| hDLG interacts with DAP-1beta. | BIND | 9286858 | ||
| DLGAP1 | DLG3 | Two-hybrid | BioGRID | 9115257 |
| DLGAP1 | DYNLL2 | DAP-1 interacts with DLC-2. | BIND | 11122378 |
| - | HPRD,BioGRID | 10844022 | ||
| DLGAP1 | SORBS2 | - | HPRD,BioGRID | 10521485 |
| DLGAP1 | TANC1 | - | HPRD | 15673434 |
| DLGAP1 | DYNLL1 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 10844022 |
| DAP-1 interacts with DLC-1. | BIND | 11122378 | ||
| DLC8 interacts with GKAP. This interaction was modeled on a demonstrated interaction between DLC8 from an unspecified species and human GKAP. | BIND | 11148209 | ||
| DLGAP2 | SHANK2 | Two-hybrid | BioGRID | 10527873 |
| DLGAP2 | DLG1 | hDLG interacts with DAP-2. | BIND | 9286858 |
| DLGAP2 | SORBS2 | - | HPRD | 10521485 |
| DLGAP2 | DLG4 | - | HPRD | 9286858 |
| Reconstituted Complex; Two-hybrid | BioGRID | 9115257 | ||
| DLGAP2 | DLG4 | - | HPRD | 9286858 |
| Reconstituted Complex; Two-hybrid | BioGRID | 9115257 | ||
| ARHGEF7 | SHANK2 | - | HPRD,BioGRID | 12626503 |
| ARHGEF7 | CDC42 | ARHGEF7 (p85Cool-1) interacts with Cdc42. | BIND | 15649357 |
| ARHGEF7 | SHANK1 | - | HPRD,BioGRID | 12626503 |
| ARHGEF7 | TGFBR2 | T-beta-RII interacts with Beta-PIX. This interaction was modeled on a demonstrated interaction between human T-beta-RII and mouse Beta-PIX. | BIND | 15761153 |
| ARHGEF7 | ARHGEF6 | ARHGEF6 interacts with ARHGEF7 | BIND | 12499396 |
| ARHGEF7 | CBL | Two-hybrid | BioGRID | 12935897 |
| ARHGEF7 | PPM1F | - | HPRD,BioGRID | 11864573 |
| ARHGEF7 | PAK2 | - | HPRD,BioGRID | 12226077 |
| ARHGEF7 | PAK1 | - | HPRD,BioGRID | 11157752|12006652 |
| ARHGEF7 | PAK3 | - | HPRD,BioGRID | 9726964 |
| ARHGEF7 | GIT1 | Affinity Capture-Western; Two-hybrid | BioGRID | 10428811 |12473661 |
| - | HPRD | 10896954 | ||
| ARHGEF7 | TUBB3 | Two-hybrid | BioGRID | 16169070 |
| ARHGEF7 | GIT1 | Affinity Capture-Western; Two-hybrid | BioGRID | 10428811 |12473661 |
| - | HPRD | 10896954 | ||
| ARHGEF7 | GIT2 | - | HPRD | 10428811 |10896954 |
| ARHGEF7 | PPM1E | Reconstituted Complex | BioGRID | 11864573 |
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