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Protein-protein interaction for ACVR1
 Nodes,
degree=1 |
 Nodes,
degree=2 |
Protein-protein interaction data for gene ACVR1
| Degree = 1 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| ACVR1 | GDF5 | - | HPRD,BioGRID | 8702914 |
| ACVR1 | ENG | - | HPRD,BioGRID | 9872992 |
| ACVR1 | INHBC | - | HPRD | 12651901 |
| ACVR1 | ACVR1B | - | HPRD,BioGRID | 8612709 |
| ACVR1 | INHBA | - | HPRD | 11266516 |
| ACVR1 | FNTA | - | HPRD,BioGRID | 8599089 |
| ACVR1 | SMAD1 | - | HPRD | 9748228 |10583507 |10652350 |
| Affinity Capture-Western | BioGRID | 9748228 |10652350 | ||
| ACVR1 | BMP2 | - | HPRD | 8006002 |
| ACVR1 | INHBB | - | HPRD | 11266516 |
| ACVR1 | SMAD5 | Affinity Capture-Western | BioGRID | 9748228 |10652350 |
| - | HPRD | 9748228 |10583507 |10652350 | ||
| ACVR1 | BMPR2 | Affinity Capture-Western; Two-hybrid | BioGRID | 7791754 |
| ACVR1 | BMP7 | - | HPRD,BioGRID | 8006002 |
| ACVR1 | IGSF1 | - | HPRD | 11266516 |
| Degree = 2 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| GDF5 | BMPR1B | Reconstituted Complex | BioGRID | 9525338 |
| - | HPRD | 11282024 | ||
| GDF5 | BMPR1B | Reconstituted Complex | BioGRID | 9525338 |
| - | HPRD | 11282024 | ||
| GDF5 | ACVR2B | - | HPRD,BioGRID | 8702914 |
| GDF5 | ACVR2A | - | HPRD,BioGRID | 8702914 |
| GDF5 | BMPR1A | - | HPRD,BioGRID | 9525338 |11282024 |
| ENG | TGFB2 | - | HPRD | 12015308 |
| ENG | ACVR2B | Affinity Capture-Western | BioGRID | 9872992 |
| ENG | TGFB1 | - | HPRD | 12015308 |
| ENG | TGFBR2 | - | HPRD,BioGRID | 9872992 |
| ENG | ACVR2A | - | HPRD,BioGRID | 9872992 |
| ENG | TGFBR1 | - | HPRD,BioGRID | 12015308 |
| ENG | TGFB3 | - | HPRD | 9872992 |
| INHBC | ACVR2B | - | HPRD | 12651901 |
| INHBC | ACVR2A | - | HPRD | 12651901 |
| ACVR1B | SMAD2 | Affinity Capture-Western | BioGRID | 9892009 |
| ACVR1B | ACVR2B | - | HPRD | 8612709|8622651 |
| - | HPRD,BioGRID | 8612709 | ||
| ACVR1B | SMAD4 | - | HPRD | 9892009 |
| ACVR1B | TGFBRAP1 | - | HPRD | 11278302 |
| ACVR1B | XIAP | An unspecified isoform of ALK4 interacts with XIAP. This interaction was modeled on a demonstrated interaction between ALK4 from an unspecified species and human XIAP. | BIND | 11356828 |
| ACVR1B | ACVR2A | - | HPRD,BioGRID | 8612709 |
| ACVR1B | ACVR2B | - | HPRD | 8612709|8622651 |
| - | HPRD,BioGRID | 8612709 | ||
| ACVR1B | SMAD3 | Affinity Capture-Western | BioGRID | 9892009 |
| ACVR1B | SMAD7 | - | HPRD,BioGRID | 12023024 |
| ACVR1B | SNX1 | - | HPRD,BioGRID | 11279102 |
| ACVR1B | TDGF1 | - | HPRD,BioGRID | 11909953 |
| ACVR1B | SNX2 | Affinity Capture-Western | BioGRID | 11279102 |
| INHBA | ACVR2B | - | HPRD,BioGRID | 9202237 |
| INHBA | ACVR2A | Affinity Capture-Western | BioGRID | 9202237 |10746731 |
| - | HPRD | 11266516 | ||
| INHBA | TGFBR3 | - | HPRD | 10746731 |
| INHBA | FSTL3 | - | HPRD,BioGRID | 11459787 |
| INHBA | IGFBP7 | - | HPRD,BioGRID | 10859029 |
| INHBA | ACVR2A | Affinity Capture-Western | BioGRID | 9202237 |10746731 |
| - | HPRD | 11266516 | ||
| INHBA | INHA | - | HPRD | 11134153 |
| INHBA | CHRDL2 | - | HPRD,BioGRID | 15094188 |
| FNTA | PTP4A2 | Affinity Capture-MS | BioGRID | 17353931 |
| FNTA | FNTB | - | HPRD | 12825937 |
| FNTA | TGFBR1 | - | HPRD,BioGRID | 8530343 |
| FNTA | TGFB1 | - | HPRD,BioGRID | 8599089 |
| SMAD1 | LEF1 | - | HPRD,BioGRID | 10890911 |
| SMAD1 | CREBBP | Affinity Capture-Western | BioGRID | 10673036 |11239394 |
| SMAD1 | HIPK2 | - | HPRD,BioGRID | 12874272 |
| SMAD1 | RUNX2 | Affinity Capture-Western | BioGRID | 10531362 |10962029 |
| SMAD1 | FOXG1 | - | HPRD,BioGRID | 11387330 |
| SMAD1 | PSMB4 | - | HPRD,BioGRID | 12097147 |
| SMAD1 | SNX6 | - | HPRD | 11279102 |
| SMAD1 | LEMD3 | LEMD3 interacts with Smad1. This interaction was modelled on a demonstrated interaction between human LEMD3 and mouse Smad1. | BIND | 15489854 |
| SMAD1 | EP300 | - | HPRD,BioGRID | 10673036 |
| SMAD1 | SNIP1 | - | HPRD,BioGRID | 10887155 |
| SMAD1 | SMAD6 | - | HPRD | 11483516 |
| SMAD1 | ZEB2 | - | HPRD | 10400677 |
| SMAD1 | ZNF8 | - | HPRD | 12370310 |
| SMAD1 | STUB1 | Smad1 interacts with CHIP. This interaction was modeled on a demonstrated interaction between Smad1 and CHIP, both from an unspecified species. | BIND | 15708501 |
| SMAD1 | BMPR1A | - | HPRD | 11438941 |
| SMAD1 | RPS27A | Two-hybrid | BioGRID | 11438941 |
| SMAD1 | ZEB1 | Affinity Capture-Western | BioGRID | 12743038 |
| SMAD1 | XPO1 | - | HPRD | 12519765 |
| SMAD1 | SMAD4 | - | HPRD | 10400705 |11700304 |
| Affinity Capture-Western; Co-fractionation | BioGRID | 10531362 |11700304 |12874272 | ||
| Smad4 interacts with Smad1. | BIND | 15761153 | ||
| SMAD1 | TOB1 | - | HPRD,BioGRID | 11163184 |
| SMAD1 | SKIL | Smad1 interacts with SnoN. This interaction was modeled on a demonstrated interaction between SnoN from an unspecified source and human Smad1. | BIND | 12426322 |
| SMAD1 | SKI | Affinity Capture-Western; Reconstituted Complex | BioGRID | 12874272 |
| SMAD1 | RUNX1 | Affinity Capture-Western | BioGRID | 10531362 |
| SMAD1 | STAT3 | Affinity Capture-Western | BioGRID | 10205054 |
| SMAD1 | OAZ3 | Two-hybrid | BioGRID | 11438941 |
| SMAD1 | ZNF423 | - | HPRD,BioGRID | 10660046 |
| SMAD1 | SMAD4 | - | HPRD | 10400705 |11700304 |
| Affinity Capture-Western; Co-fractionation | BioGRID | 10531362 |11700304 |12874272 | ||
| Smad4 interacts with Smad1. | BIND | 15761153 | ||
| SMAD1 | GDF6 | - | HPRD | 15246821 |
| SMAD1 | TGIF1 | Affinity Capture-Western | BioGRID | 10199400 |
| SMAD1 | NEDD9 | - | HPRD,BioGRID | 11118211 |
| SMAD1 | DVL1 | Reconstituted Complex | BioGRID | 12650946 |
| SMAD1 | SMURF2 | SMAD1 interacts with SMURF2. | BIND | 15761153 |
| - | HPRD,BioGRID | 11016919 | ||
| SMAD1 | RAN | SMAD1 interacts with RAN. This interaction was modeled on a demonstrated interaction between human SMAD1 and mouse RAN. | BIND | 15761153 |
| SMAD1 | HOXC8 | - | HPRD,BioGRID | 10224145 |11139569 |
| SMAD1 | ECSIT | - | HPRD | 14633973 |
| SMAD1 | PARD3B | Reconstituted Complex | BioGRID | 12650946 |
| SMAD1 | SMAD4 | - | HPRD | 10400705 |11700304 |
| Affinity Capture-Western; Co-fractionation | BioGRID | 10531362 |11700304 |12874272 | ||
| Smad4 interacts with Smad1. | BIND | 15761153 | ||
| SMAD1 | GLI3 | - | HPRD | 9843199 |
| SMAD1 | RUNX3 | Affinity Capture-Western | BioGRID | 10531362 |
| SMAD1 | ZNF521 | - | HPRD | 14630787 |
| SMAD1 | UBA52 | Two-hybrid | BioGRID | 11438941 |
| SMAD1 | ERBB2IP | - | HPRD,BioGRID | 12650946 |
| SMAD1 | NEUROG1 | - | HPRD,BioGRID | 11239394 |
| SMAD1 | SMURF2 | SMAD1 interacts with SMURF2. | BIND | 15761153 |
| - | HPRD,BioGRID | 11016919 | ||
| BMP2 | BMPER | - | HPRD | 12897139 |
| BMP2 | BMPR1B | Reconstituted Complex | BioGRID | 10712517 |
| - | HPRD | 9872992 | ||
| BMP2 | SOSTDC1 | - | HPRD,BioGRID | 14623234 |15020244 |
| BMP2 | ACTR2 | Reconstituted Complex | BioGRID | 10880444 |
| BMP2 | BMPR1B | Reconstituted Complex | BioGRID | 10712517 |
| - | HPRD | 9872992 | ||
| BMP2 | ASCL1 | - | HPRD | 9197246 |
| BMP2 | TGFB1 | - | HPRD | 11456401 |
| BMP2 | BMPR1A | Co-crystal Structure; Reconstituted Complex | BioGRID | 10692589 |10712517 |10880444 |11263668 |
| - | HPRD | 10692589 |10881198 |11263668|11263668 | ||
| BMP2 | TGFB2 | - | HPRD | 9493905 |
| BMP2 | COL2A1 | - | HPRD,BioGRID | 10085302 |
| BMP2 | MGP | - | HPRD,BioGRID | 11741887 |
| BMP2 | BMPR1A | Co-crystal Structure; Reconstituted Complex | BioGRID | 10692589 |10712517 |10880444 |11263668 |
| - | HPRD | 10692589 |10881198 |11263668|11263668 | ||
| BMP2 | NOG | - | HPRD | 10657699 |
| INHBB | ACVR2A | Affinity Capture-Western | BioGRID | 9202237 |
| - | HPRD | 11266516 | ||
| INHBB | ACVR2A | Affinity Capture-Western | BioGRID | 9202237 |
| - | HPRD | 11266516 | ||
| INHBB | ACVR1C | - | HPRD | 15196700 |
| INHBB | INHA | - | HPRD | 11134153 |
| INHBB | ACVR2B | - | HPRD,BioGRID | 9202237 |
| SMAD5 | RUNX2 | Affinity Capture-Western | BioGRID | 10531362 |
| SMAD5 | ZEB2 | - | HPRD | 10400677 |
| SMAD5 | GDF6 | - | HPRD | 15246821 |
| SMAD5 | SMAD4 | Affinity Capture-Western | BioGRID | 10531362 |
| SMAD5 | BMP6 | - | HPRD | 10504300 |
| SMAD5 | ZNF8 | - | HPRD | 12370310 |
| SMAD5 | TOB1 | - | HPRD,BioGRID | 11163184 |
| SMAD5 | RUNX1 | Affinity Capture-Western | BioGRID | 10531362 |
| SMAD5 | RUNX3 | Affinity Capture-Western | BioGRID | 10531362 |
| BMPR2 | NOL5A | - | HPRD | 15188402 |
| BMPR2 | BMP4 | - | HPRD,BioGRID | 7644468 |8702914 |
| BMPR2 | BMP6 | Affinity Capture-Western | BioGRID | 10504300 |
| - | HPRD | 11401330 | ||
| BMPR2 | GCGR | Affinity Capture-MS | BioGRID | 15188402 |
| BMPR2 | GDF9 | - | HPRD,BioGRID | 12135884 |
| BMPR2 | CRYAB | Affinity Capture-MS | BioGRID | 15188402 |
| BMPR2 | TRPC1 | - | HPRD | 15188402 |
| BMPR2 | DYNLT1 | - | HPRD | 14583445 |
| BMPR2 | BMP6 | Affinity Capture-Western | BioGRID | 10504300 |
| - | HPRD | 11401330 | ||
| BMPR2 | BMPR1B | - | HPRD,BioGRID | 10712517 |
| BMPR2 | FRS3 | Affinity Capture-MS | BioGRID | 15188402 |
| BMPR2 | TWF1 | - | HPRD | 15188402 |
| BMPR2 | TSR1 | Two-hybrid | BioGRID | 7791754 |
| BMPR2 | GDF6 | - | HPRD,BioGRID | 9525338 |
| BMPR2 | CES3 | Affinity Capture-MS | BioGRID | 15188402 |
| BMPR2 | LIMK1 | - | HPRD,BioGRID | 12963706 |
| BMPR2 | PDZRN3 | - | HPRD | 15188402 |
| BMPR2 | LSM10 | - | HPRD | 15188402 |
| BMPR2 | TGFBR1 | Two-hybrid | BioGRID | 7791754 |
| BMPR2 | BMPR1A | - | HPRD,BioGRID | 10712517 |
| BMP7 | BMPR1A | Reconstituted Complex | BioGRID | 8006002 |
| - | HPRD | 7791754 |8605097 | ||
| BMP7 | ACVR2B | - | HPRD,BioGRID | 9748228 |
| BMP7 | ACVR2A | - | HPRD,BioGRID | 9748228 |
| BMP7 | NCOA3 | - | HPRD | 7791754 |
| BMP7 | SOSTDC1 | - | HPRD,BioGRID | 14623234 |15020244 |
| BMP7 | BMPR1A | Reconstituted Complex | BioGRID | 8006002 |
| - | HPRD | 7791754 |8605097 | ||
| BMP7 | BMPR1B | - | HPRD | 8605097 |
| Reconstituted Complex | BioGRID | 8006002 | ||
| BMP7 | NOG | - | HPRD,BioGRID | 12478285 |
| BMP7 | BMPR1B | - | HPRD | 8605097 |
| Reconstituted Complex | BioGRID | 8006002 | ||
| IGSF1 | HECTD1 | - | HPRD | 12421765 |
| IGSF1 | ACVR2A | - | HPRD | 11266516 |
| IGSF1 | IGF1 | - | HPRD,BioGRID | 11344214 |
| IGSF1 | ACVR2B | - | HPRD | 11266516 |
| IGSF1 | RANBP10 | - | HPRD | 12421765 |
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