Gene Page: LRPPRC

Summary
GeneID  10128
Symbol  LRPPRC
Synonyms  CLONE-23970|GP130|LRP130|LSFC
Description  leucine-rich PPR-motif containing
See related  HGNC:15714|MIM:607544|Ensembl:ENSG00000138095|HPRD:06343|
Locus tag  -
Gene type  protein-coding
Map location  2p21
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0113 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PHF60.970.94
PRPF40A0.970.96
FAM76B0.970.95
MSH60.960.96
PDCL0.960.93
NUP2050.960.95
PHF160.960.93
SMC30.960.96
DHX90.960.94
SP30.960.95
Top 10 negatively co-expressed genes
HLA-F-0.68-0.77
C5orf53-0.67-0.73
PTH1R-0.66-0.75
AIFM3-0.66-0.74
TNFSF12-0.66-0.68
AF347015.31-0.66-0.86
AF347015.27-0.65-0.84
FBXO2-0.65-0.66
FXYD1-0.65-0.86
MT-CO2-0.65-0.87
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003677DNA bindingIEA-
GO:0003723RNA bindingNAS12832482 
GO:0005515protein bindingIPI17050673 |17353931 
GO:0008017microtubule bindingTAS12762840 
GO:0051015actin filament bindingIDA12762840 
GO:0048487beta-tubulin bindingIDA12762840 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0006350transcriptionIEA-
GO:0006810transportIEA-
GO:0051028mRNA transportIEA-
GO:0047497mitochondrion transport along microtubuleTAS12762840 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000794condensed nuclear chromosomeIDA12762840 
GO:0005856cytoskeletonIDA12762840 
GO:0005634nucleusIDA12832482 
GO:0005637nuclear inner membraneIEA-
GO:0005640nuclear outer membraneIEA-
GO:0005739mitochondrionIDA12832482 
GO:0016020membraneIEA-
GO:0048471perinuclear region of cytoplasmIDA12762840 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ARF6DKFZp564M0264ADP-ribosylation factor 6Affinity Capture-MSBioGRID17353931 
CECR2KIAA1740cat eye syndrome chromosome region, candidate 2-HPRD,BioGRID11827465 
GABARAPL2ATG8 | GATE-16 | GATE16 | GEF-2 | GEF2GABA(A) receptor-associated protein-like 2Affinity Capture-MSBioGRID17353931 
GSTK1GST13glutathione S-transferase kappa 1Affinity Capture-MSBioGRID17353931 
HEBP2C6ORF34B | C6orf34 | KIAA1244 | PP23 | SOULheme binding protein 2-HPRD,BioGRID11827465 
IKBKEIKK-i | IKKE | IKKI | KIAA0151 | MGC125294 | MGC125295 | MGC125297inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilonAffinity Capture-MSBioGRID17353931 
MAGEA6MAGE-3b | MAGE3B | MAGE6 | MGC52297melanoma antigen family A, 6Affinity Capture-MSBioGRID17353931 
MAGED1DLXIN-1 | NRAGEmelanoma antigen family D, 1Affinity Capture-MSBioGRID17353931 
MAP1SBPY2IP1 | C19orf5 | FLJ10669 | MAP8 | MGC133087 | VCY2IP-1 | VCY2IP1microtubule-associated protein 1S-HPRD,BioGRID11827465 
NEK6SID6-1512NIMA (never in mitosis gene a)-related kinase 6Affinity Capture-MSBioGRID17353931 
PHLDA3TIH1pleckstrin homology-like domain, family A, member 3Affinity Capture-MSBioGRID17353931 
PTP4A3PRL-3 | PRL-R | PRL3protein tyrosine phosphatase type IVA, member 3Affinity Capture-MSBioGRID17353931 
TNFRSF10DCD264 | DCR2 | TRAILR4 | TRUNDDtumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domainAffinity Capture-MSBioGRID17353931 
UXTART-27ubiquitously-expressed transcript-HPRD,BioGRID11827465 
WDR8FLJ20430 | MGC99569WD repeat domain 8Affinity Capture-MSBioGRID17353931 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN 362238All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_2HR_DN 8853All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_6HR_DN 167100All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_24HR_UP 557331All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_DN 1375806All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP 633376All SZGR genes in this pathway
OUELLET_OVARIAN_CANCER_INVASIVE_VS_LMP_UP 11785All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN 855609All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN 483336All SZGR genes in this pathway
KIM_MYC_AMPLIFICATION_TARGETS_UP 201127All SZGR genes in this pathway
LIAO_METASTASIS 539324All SZGR genes in this pathway
SHIPP_DLBCL_CURED_VS_FATAL_DN 4530All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN 546351All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
RODWELL_AGING_KIDNEY_NO_BLOOD_DN 15093All SZGR genes in this pathway
RODWELL_AGING_KIDNEY_DN 14588All SZGR genes in this pathway
BACOLOD_RESISTANCE_TO_ALKYLATING_AGENTS_DN 6045All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP 953554All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN 911527All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN 1011592All SZGR genes in this pathway
WONG_MITOCHONDRIA_GENE_MODULE 217122All SZGR genes in this pathway
BOCHKIS_FOXA2_TARGETS 425261All SZGR genes in this pathway
MOOTHA_PGC 420269All SZGR genes in this pathway
LEE_RECENT_THYMIC_EMIGRANT 227128All SZGR genes in this pathway
SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6 456285All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_UP 605377All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP 548370All SZGR genes in this pathway
LEE_BMP2_TARGETS_DN 882538All SZGR genes in this pathway
ROESSLER_LIVER_CANCER_METASTASIS_DN 5329All SZGR genes in this pathway


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.