Gene Page: BCKDK

Summary
GeneID  10295
Symbol  BCKDK
Synonyms  -
Description  branched chain ketoacid dehydrogenase kinase
See related  HGNC:16902|Ensembl:ENSG00000103507|HPRD:12523|
Locus tag  -
Gene type  protein-coding
Map location  16p11.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.01775 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000155two-component sensor activityIEA-
GO:0005515protein bindingIPI17353931 
GO:0005524ATP bindingIEA-
GO:0005524ATP bindingISS-
GO:0004674protein serine/threonine kinase activityISS-
GO:0016301kinase activityIEA-
GO:0047323[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0009083branched chain family amino acid catabolic processISS-
GO:0009083branched chain family amino acid catabolic processTAS11839747 
GO:0007165signal transductionIEA-
GO:0016310phosphorylationISS-
GO:0016310phosphorylationTAS11839747 
GO:0018106peptidyl-histidine phosphorylationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005739mitochondrionTAS11839747 
GO:0005759mitochondrial matrixIEA-
GO:0005947mitochondrial alpha-ketoglutarate dehydrogenase complexISS-
GO:0005947mitochondrial alpha-ketoglutarate dehydrogenase complexTAS11839747 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BCKDHABCKDE1A | FLJ45695 | MSU | MSUD1 | OVD1Abranched chain keto acid dehydrogenase E1, alpha polypeptideAffinity Capture-MSBioGRID17353931 
BCKDHBE1B | FLJ17880 | dJ279A18.1branched chain keto acid dehydrogenase E1, beta polypeptide-HPRD1377677 
CAB39CGI-66 | FLJ22682 | MO25calcium binding protein 39Affinity Capture-MSBioGRID17353931 
CAB39LFLJ12577 | MO25-BETA | MO2L | RP11-103J18.3 | bA103J18.3calcium binding protein 39-likeAffinity Capture-MSBioGRID17353931 
DBTBCATE2 | E2 | E2B | MGC9061dihydrolipoamide branched chain transacylase E2-HPRD1377677 
DLDDLDH | E3 | GCSL | LAD | PHE3dihydrolipoamide dehydrogenase-HPRD15576032 
FAM98BFLJ38426family with sequence similarity 98, member BAffinity Capture-MSBioGRID17353931 
MUTEDDKFZp686E2287 | MUmuted homolog (mouse)-HPRD15102850 
RNF219C13orf7 | DKFZp686A01276 | DKFZp686N15250 | DKFZp686O03173 | FLJ13449 | FLJ25774ring finger protein 219Affinity Capture-MSBioGRID17353931 
RTCD1RPCRNA terminal phosphate cyclase domain 1Affinity Capture-MSBioGRID17353931 
TRAF4CART1 | MLN62 | RNF83TNF receptor-associated factor 4TRAF4 interacts with BCKDK.BIND12023963 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
GARY_CD5_TARGETS_UP 473314All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_UP 530342All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
MOHANKUMAR_TLX1_TARGETS_UP 414287All SZGR genes in this pathway
LU_IL4_SIGNALING 9456All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_DN 504323All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_DN 540340All SZGR genes in this pathway
MOOTHA_HUMAN_MITODB_6_2002 429260All SZGR genes in this pathway
MOOTHA_MITOCHONDRIA 447277All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_1HR_DN 222147All SZGR genes in this pathway
KRIEG_HYPOXIA_NOT_VIA_KDM3A 770480All SZGR genes in this pathway


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