Gene Page: TNIP1

Summary
GeneID  10318
Symbol  TNIP1
Synonyms  ABIN-1|KIAA0113|NAF1|VAN
Description  TNFAIP3 interacting protein 1
See related  HGNC:16903|MIM:607714|Ensembl:ENSG00000145901|HPRD:09216|
Locus tag  -
Gene type  protein-coding
Map location  5q32-q33.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0032 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00459 
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.01718 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
MRPL90.870.85
SUMO20.850.90
LSM60.840.83
TBCA0.840.88
DNAJC80.840.84
SARNP0.830.85
SRP140.830.83
LSM30.830.86
THOC40.820.86
FAM32A0.820.86
Top 10 negatively co-expressed genes
AF347015.33-0.65-0.72
AF347015.26-0.64-0.73
MT-CO2-0.64-0.67
APOL3-0.64-0.72
AF347015.9-0.64-0.74
HLA-F-0.63-0.68
TINAGL1-0.63-0.71
AF347015.2-0.63-0.70
MT-CYB-0.63-0.70
SLC6A12-0.61-0.67
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingTAS11090181 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0009101glycoprotein biosynthetic processIDA9923610 
GO:0006412translationTAS9923610 
GO:0009405pathogenesisTAS9923610 
GO:0006952defense responseTAS9923610 
GO:0045071negative regulation of viral genome replicationTAS9923610 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005622intracellularTAS9923610 
GO:0005634nucleusIEA-
GO:0005737cytoplasmIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
MAGEB18MGC33889melanoma antigen family B, 18Affinity Capture-Western
Two-hybrid		BioGRID16189514 
MAPK1ERK | ERK2 | ERT1 | MAPK2 | P42MAPK | PRKM1 | PRKM2 | p38 | p40 | p41 | p41mapkmitogen-activated protein kinase 1Naf1-alpha interacts with ERK2.BIND12220502 
Affinity Capture-Western
Reconstituted Complex
Two-hybrid		BioGRID12220502 
TNFAIP3A20 | MGC104522 | MGC138687 | MGC138688 | OTUD7C | TNFA1P2tumor necrosis factor, alpha-induced protein 3-HPRD,BioGRID10385526 |12965196 
TTF2HuF2transcription termination factor, RNA polymerase IITwo-hybridBioGRID12927788 
HuF2 interacts with NAF1.BIND12927788 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP 485293All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_UP 380215All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_DN 5036All SZGR genes in this pathway
GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_DN 180101All SZGR genes in this pathway
DITTMER_PTHLH_TARGETS_UP 11268All SZGR genes in this pathway
WAMUNYOKOLI_OVARIAN_CANCER_LMP_UP 265158All SZGR genes in this pathway
PROVENZANI_METASTASIS_DN 13694All SZGR genes in this pathway
RASHI_RESPONSE_TO_IONIZING_RADIATION_2 12792All SZGR genes in this pathway
RASHI_NFKB1_TARGETS 1918All SZGR genes in this pathway
XU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_UP 148All SZGR genes in this pathway
DIRMEIER_LMP1_RESPONSE_LATE_UP 5741All SZGR genes in this pathway
ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP 223140All SZGR genes in this pathway
KAUFFMANN_DNA_REPLICATION_GENES 14787All SZGR genes in this pathway
SANA_TNF_SIGNALING_UP 8356All SZGR genes in this pathway
OKUMURA_INFLAMMATORY_RESPONSE_LPS 183115All SZGR genes in this pathway
GALINDO_IMMUNE_RESPONSE_TO_ENTEROTOXIN 8567All SZGR genes in this pathway
LEI_MYB_TARGETS 318215All SZGR genes in this pathway
NEMETH_INFLAMMATORY_RESPONSE_LPS_UP 8864All SZGR genes in this pathway
ZHOU_TNF_SIGNALING_4HR 5436All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_18HR_DN 178121All SZGR genes in this pathway
SESTO_RESPONSE_TO_UV_C1 7245All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4 307185All SZGR genes in this pathway
SEKI_INFLAMMATORY_RESPONSE_LPS_UP 7756All SZGR genes in this pathway
LINDSTEDT_DENDRITIC_CELL_MATURATION_B 5336All SZGR genes in this pathway
HINATA_NFKB_TARGETS_KERATINOCYTE_UP 9163All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
MIKKELSEN_IPS_LCP_WITH_H3K4ME3 174100All SZGR genes in this pathway
TIAN_TNF_SIGNALING_VIA_NFKB 2821All SZGR genes in this pathway
CHANDRAN_METASTASIS_DN 306191All SZGR genes in this pathway
KARLSSON_TGFB1_TARGETS_DN 207139All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_UP 430288All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_LATE 1137655All SZGR genes in this pathway
FARDIN_HYPOXIA_11 3229All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D 882506All SZGR genes in this pathway
KRIEG_HYPOXIA_NOT_VIA_KDM3A 770480All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_DN 784464All SZGR genes in this pathway
PHONG_TNF_RESPONSE_NOT_VIA_P38 337236All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-19726732m8hsa-miR-19aUGUGCAAAUCUAUGCAAAACUGA
hsa-miR-19bUGUGCAAAUCCAUGCAAAACUGA
miR-3704304361Ahsa-miR-370brainGCCUGCUGGGGUGGAACCUGG
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.