Gene Page: GLRX3

Summary
GeneID  10539
Symbol  GLRX3
Synonyms  FLJ11864|GLRX4|GRX3|GRX4|PICOT|TXNL2|TXNL3|bA500G10.4
Description  glutaredoxin 3
See related  HGNC:15987|Ensembl:ENSG00000108010|HPRD:10153|
Locus tag  -
Gene type  protein-coding
Map location  10q26
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.03487 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
GDA0.610.58
RASGRF20.600.51
PRKCB0.590.55
KCNMA10.590.54
KIAA10450.590.53
IQSEC20.590.55
SCN8A0.590.49
ARHGAP260.590.51
MAPK90.580.56
SGTB0.580.53
Top 10 negatively co-expressed genes
BCL7C-0.32-0.36
SH2D2A-0.29-0.30
NME4-0.29-0.34
RPL28-0.29-0.34
RAB13-0.28-0.28
RPL18-0.28-0.31
HYAL2-0.28-0.27
RPL23A-0.28-0.26
RPL35-0.28-0.31
RPL36-0.28-0.32
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI10636891 |17353931 
GO:0009055electron carrier activityIEA-
GO:0015035protein disulfide oxidoreductase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0045454cell redox homeostasisIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ADAMTSL4TSRC1ADAMTS-like 4Two-hybridBioGRID16189514 
C10orf4F26C11.1-like | FRA10A | FRA10AC1chromosome 10 open reading frame 4Two-hybridBioGRID16169070 
CIAPIN12810413N20Rik | Anamorsin | DRE2 | PRO0915cytokine induced apoptosis inhibitor 1Two-hybridBioGRID16189514 
EFEMP2FBLN4 | MBP1 | UPH1EGF-containing fibulin-like extracellular matrix protein 2Two-hybridBioGRID16189514 
HEXDCFLJ23825hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containingTwo-hybridBioGRID16169070 
KRTAP4-12KAP4.12 | KRTAP4.12keratin associated protein 4-12Two-hybridBioGRID16189514 
NADKFLJ13052 | FLJ37724 | dJ283E3.1NAD kinaseTwo-hybridBioGRID16189514 
PLSCR1MMTRA1Bphospholipid scramblase 1Two-hybridBioGRID16189514 
PRKCQMGC126514 | MGC141919 | PRKCT | nPKC-thetaprotein kinase C, theta-HPRD,BioGRID10636891 
RGS20RGSZ1 | ZGAP1regulator of G-protein signaling 20Affinity Capture-MSBioGRID17353931 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_LOBULAR_NORMAL_UP 7350All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_UP 204140All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP 1278748All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP 633376All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP 722443All SZGR genes in this pathway
CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP 239157All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP 1142669All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP 227137All SZGR genes in this pathway
WEI_MYCN_TARGETS_WITH_E_BOX 795478All SZGR genes in this pathway
AMIT_EGF_RESPONSE_480_HELA 164118All SZGR genes in this pathway
WANG_TARGETS_OF_MLL_CBP_FUSION_DN 4531All SZGR genes in this pathway
WANG_SMARCE1_TARGETS_DN 371218All SZGR genes in this pathway
HU_GENOTOXIN_ACTION_DIRECT_VS_INDIRECT_24HR 5538All SZGR genes in this pathway
MCCLUNG_CREB1_TARGETS_UP 10072All SZGR genes in this pathway
LEIN_MEDULLA_MARKERS 8148All SZGR genes in this pathway
MCGOWAN_RSP6_TARGETS_UP 1812All SZGR genes in this pathway
CHANG_CORE_SERUM_RESPONSE_UP 212128All SZGR genes in this pathway
MILI_PSEUDOPODIA_HAPTOTAXIS_DN 668419All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_DN 553343All SZGR genes in this pathway


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