|
GeneID |
10595
|
Symbol |
ERN2
|
Synonyms |
IRE1b
|
Description |
endoplasmic reticulum to nucleus signaling 2 |
See related |
HGNC:16942|MIM:604034|Ensembl:ENSG00000134398|HPRD:04944| |
Locus tag |
- |
Gene type |
protein-coding |
Map location |
16p12.2 |
|
|
|
Gene set name |
Method of gene set |
Evidence |
Info |
GSMA_IIE | genome scan meta-analysis (European-ancestry samples) | Psr: 0.01775 | |
|
|
General Gene Expression (microarray) ? |
|
|
|
Gene Expression in Brain Regions (new) |
|
|
Top co-expressed genes in Brain Regions (new) |
|
Gene | Pearson's Correlation | Spearman's Correlation | | |
Top 10 positively co-expressed genes |
ENOSF1 | 0.61 | 0.53 | | |
CHD1L | 0.61 | 0.58 | | |
BEST1 | 0.59 | 0.53 | | |
KIAA1755 | 0.58 | 0.58 | | |
CDC14B | 0.58 | 0.56 | | |
CYTSB | 0.58 | 0.57 | | |
CA14 | 0.57 | 0.56 | | |
IGSF11 | 0.57 | 0.52 | | |
FAM63A | 0.56 | 0.51 | | |
LITAF | 0.56 | 0.53 | | |
Top 10 negatively co-expressed genes | C1orf86 | -0.40 | -0.44 | | |
EMID1 | -0.38 | -0.42 | | |
AC011491.1 | -0.35 | -0.39 | | |
RPRM | -0.34 | -0.38 | | |
RASGEF1C | -0.34 | -0.32 | | |
CD1D | -0.34 | -0.36 | | |
COMTD1 | -0.34 | -0.37 | | |
GPRIN1 | -0.33 | -0.32 | | |
SLC1A6 | -0.33 | -0.38 | | |
LRFN4 | -0.33 | -0.35 | | |
|
Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
---|
GO:0000166 | nucleotide binding | IEA | | - |
GO:0000287 | magnesium ion binding | IDA | | 11175748 |
GO:0005524 | ATP binding | IDA | | 11175748 |
GO:0004519 | endonuclease activity | IDA | | 11175748 |
GO:0004674 | protein serine/threonine kinase activity | IDA | | 11175748 |
GO:0016787 | hydrolase activity | IEA | | - |
GO:0016740 | transferase activity | IEA | | - |
GO:0016891 | endoribonuclease activity, producing 5'-phosphomonoesters | IEA | | - |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
---|
GO:0006355 | regulation of transcription, DNA-dependent | IEA | | - |
GO:0006397 | mRNA processing | IEA | | - |
GO:0006468 | protein amino acid phosphorylation | IDA | | 11175748 |
GO:0016075 | rRNA catabolic process | IDA | | 11175748 |
GO:0006917 | induction of apoptosis | IMP | | 11175748 |
GO:0006950 | response to stress | IEA | | - |
GO:0007050 | cell cycle arrest | IEA | | - |
GO:0006915 | apoptosis | IEA | | - |
GO:0016481 | negative regulation of transcription | IMP | | 11175748 |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
---|
GO:0005789 | endoplasmic reticulum membrane | IEA | | - |
GO:0005783 | endoplasmic reticulum | IEA | | - |
GO:0016020 | membrane | IEA | | - |
GO:0016021 | integral to membrane | IEA | | - |
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