Gene Page: STAMBP

Summary
GeneID  10617
Symbol  STAMBP
Synonyms  AMSH|MGC126516|MGC126518
Description  STAM binding protein
See related  HGNC:16950|MIM:606247|Ensembl:ENSG00000124356|HPRD:05877|
Locus tag  -
Gene type  protein-coding
Map location  2p13.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0096 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
MKKS0.860.84
TMEM1110.860.84
PRKAG10.860.80
GABARAPL20.860.84
MRPS70.860.84
TMEM850.850.79
COPS40.850.83
TSFM0.850.80
SNX170.840.85
YIPF10.840.81
Top 10 negatively co-expressed genes
AF347015.18-0.60-0.36
AF347015.2-0.52-0.25
AF347015.26-0.51-0.28
AC010300.1-0.51-0.50
AC100783.1-0.51-0.39
AF347015.8-0.49-0.25
MT-ATP8-0.48-0.26
C10orf108-0.48-0.43
AC016705.1-0.48-0.34
AF347015.21-0.47-0.20
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI10383417 |14755250 
GO:0004221ubiquitin thiolesterase activityIEA-
GO:0008270zinc ion bindingIEA-
GO:0008237metallopeptidase activityIEA-
GO:0008233peptidase activityIEA-
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006511ubiquitin-dependent protein catabolic processIEA-
GO:0007259JAK-STAT cascadeTAS10383417 
GO:0008284positive regulation of cell proliferationTAS10383417 
GO:0006916anti-apoptosisIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusTAS10383417 
GO:0005737cytoplasmIEA-
GO:0016020membraneIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
GRAP2GADS | GRAP-2 | GRB2L | GRBLG | GRID | GRPL | GrbX | Grf40 | Mona | P38GRB2-related adaptor protein 2-HPRD,BioGRID10224278 
RNF11CGI-123 | MGC51169 | SID1669ring finger protein 11Affinity Capture-Western
Reconstituted Complex
Two-hybrid		BioGRID14755250 
RNF11 interacts with AMSH.BIND14755250 
SMAD6HsT17432 | MADH6 | MADH7SMAD family member 6-HPRD,BioGRID11483516 
SMAD7CRCS3 | FLJ16482 | MADH7 | MADH8SMAD family member 7-HPRD,BioGRID11483516 
SMURF2DKFZp686F0270 | MGC138150SMAD specific E3 ubiquitin protein ligase 2Affinity Capture-WesternBioGRID14755250 
STAMDKFZp686J2352 | STAM1signal transducing adaptor molecule (SH3 domain and ITAM motif) 1-HPRD,BioGRID10383417 
STAM2DKFZp564C047 | Hbp | STAM2A | STAM2Bsignal transducing adaptor molecule (SH3 domain and ITAM motif) 2-HPRD,BioGRID10899310 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_ENDOCYTOSIS 183132All SZGR genes in this pathway
PID_ERBB1_INTERNALIZATION_PATHWAY 4135All SZGR genes in this pathway
HOLLMANN_APOPTOSIS_VIA_CD40_DN 267178All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_1_UP 380236All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_2_UP 418263All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_DN 1375806All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_UP 293179All SZGR genes in this pathway
DACOSTA_ERCC3_ALLELE_XPCS_VS_TTD_DN 3627All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN 514319All SZGR genes in this pathway
KIM_GERMINAL_CENTER_T_HELPER_UP 6642All SZGR genes in this pathway
PEART_HDAC_PROLIFERATION_CLUSTER_UP 5735All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_10HR_DN 5637All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_14HR_DN 298200All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR 681420All SZGR genes in this pathway
JIANG_HYPOXIA_NORMAL 311205All SZGR genes in this pathway
KYNG_WERNER_SYNDROM_AND_NORMAL_AGING_UP 9362All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_UP 242159All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_DN 784464All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-135424430m8hsa-miR-135aUAUGGCUUUUUAUUCCUAUGUGA
hsa-miR-135bUAUGGCUUUUCAUUCCUAUGUG
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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