Gene Page: RGS14

Summary
GeneID  10636
Symbol  RGS14
Synonyms  -
Description  regulator of G-protein signaling 14
See related  HGNC:9996|MIM:602513|Ensembl:ENSG00000169220|HPRD:03944|
Locus tag  -
Gene type  protein-coding
Map location  5q35.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.0276 
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0036 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
AC113191.10.930.90
ZNF1210.880.88
PCDHB110.870.84
ZNF8520.850.82
GATAD2B0.850.91
IGF1R0.850.90
RC3H10.840.85
KIAA18530.840.83
RAD54L20.840.92
TMEM2130.840.81
Top 10 negatively co-expressed genes
SERPINB6-0.52-0.68
C5orf53-0.50-0.69
AF347015.31-0.49-0.79
LHPP-0.49-0.52
HSD17B14-0.49-0.71
AF347015.27-0.49-0.78
ACOT13-0.48-0.61
MT-CO2-0.48-0.78
IFI27-0.48-0.76
S100B-0.48-0.74
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005057receptor signaling protein activityIEA-
GO:0005096GTPase activator activityTAS9168931 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0009968negative regulation of signal transductionIEA-
GO:0008277regulation of G-protein coupled receptor protein signaling pathwayTAS9168931 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016020membraneIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
GNAI1Giguanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1-HPRD,BioGRID11387333 |11976690 
GNAI2GIP | GNAI2B | H_LUCA15.1 | H_LUCA16.1guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2-HPRD,BioGRID11387333 
GNAI387U6 | FLJ26559guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3-HPRD,BioGRID11387333 
GNAO1DKFZp686O0962 | G-ALPHA-o | GNAOguanine nucleotide binding protein (G protein), alpha activating activity polypeptide O-HPRD10926822 
RAP1AKREV-1 | KREV1 | RAP1 | SMGP21RAP1A, member of RAS oncogene family-HPRD,BioGRID10926822 
RAP2AK-REV | KREV | RAP2 | RbBP-30RAP2A, member of RAS oncogene family-HPRD,BioGRID10926822 
TRAF2MGC:45012 | TRAP | TRAP3TNF receptor-associated factor 2Two-hybridBioGRID16189514 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
LIU_SOX4_TARGETS_DN 309191All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_1_UP 380236All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_2_UP 418263All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_DN 187115All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
DARWICHE_PAPILLOMA_PROGRESSION_RISK 7444All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_UP 479299All SZGR genes in this pathway
RICKMAN_METASTASIS_DN 261155All SZGR genes in this pathway
MORI_PRE_BI_LYMPHOCYTE_DN 7749All SZGR genes in this pathway
MORI_LARGE_PRE_BII_LYMPHOCYTE_DN 5839All SZGR genes in this pathway
MORI_IMMATURE_B_LYMPHOCYTE_UP 5335All SZGR genes in this pathway
MORI_MATURE_B_LYMPHOCYTE_UP 9062All SZGR genes in this pathway
THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_DN 225163All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
RAMALHO_STEMNESS_DN 7455All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_DN 165106All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN 911527All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP 783442All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED 1229713All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_OPTIMAL_DEBULKING 246152All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
MIKKELSEN_MEF_LCP_WITH_H3K27ME3 7035All SZGR genes in this pathway
ACOSTA_PROLIFERATION_INDEPENDENT_MYC_TARGETS_UP 8451All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-324-3p294300m8hsa-miR-324-3pCCACUGCCCCAGGUGCUGCUGG
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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