Gene Page: LBX1

Summary
GeneID  10660
Symbol  LBX1
Synonyms  HPX-6|HPX6|LBX1H|homeobox
Description  ladybird homeobox 1
See related  HGNC:16960|MIM:604255|Ensembl:ENSG00000138136|HPRD:09178|
Locus tag  RP11-324L3.2
Gene type  protein-coding
Map location  10q24
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 4 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ZNF240.930.95
USP380.910.92
KLHL280.910.92
XPO40.900.92
CEP970.900.91
LMAN10.900.92
PPP4R20.890.90
ZNF4510.890.91
SOCS40.890.93
ADAM100.890.88
Top 10 negatively co-expressed genes
FXYD1-0.62-0.66
IFI27-0.60-0.66
AC018755.7-0.60-0.63
MT-CO2-0.60-0.65
AF347015.21-0.60-0.66
CXCL14-0.59-0.65
HIGD1B-0.58-0.65
MYL3-0.57-0.60
AF347015.31-0.56-0.63
AF347015.8-0.56-0.62
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003700transcription factor activityIEA-
GO:0005515protein bindingIEA-
GO:0043565sequence-specific DNA bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0048664neuron fate determinationIEAneuron (GO term level: 10)-
GO:0045665negative regulation of neuron differentiationIEAneuron (GO term level: 10)-
GO:0007519skeletal muscle developmentIEAneuron (GO term level: 8)-
GO:0007399nervous system developmentIEAneurite (GO term level: 5)-
GO:0001947heart loopingIEA-
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0008285negative regulation of cell proliferationIEA-
GO:0009653anatomical structure morphogenesisTAS8645601 
GO:0007275multicellular organismal developmentIEA-
GO:0030154cell differentiationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
GO:0005667transcription factor complexIEA-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
BORCZUK_MALIGNANT_MESOTHELIOMA_DN 10459All SZGR genes in this pathway
JAZAG_TGFB1_SIGNALING_VIA_SMAD4_UP 10866All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS 652441All SZGR genes in this pathway
LEE_AGING_CEREBELLUM_DN 8666All SZGR genes in this pathway
XU_GH1_EXOGENOUS_TARGETS_DN 12069All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K27ME3 269159All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3 349234All SZGR genes in this pathway
MIKKELSEN_MCV6_HCP_WITH_H3K27ME3 435318All SZGR genes in this pathway
MIKKELSEN_IPS_WITH_HCP_H3K27ME3 10276All SZGR genes in this pathway
MIKKELSEN_NPC_HCP_WITH_H3K27ME3 341243All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3K27ME3 590403All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_D 280158All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1371651721A,m8hsa-miR-137UAUUGCUUAAGAAUACGCGUAG
miR-25/32/92/363/367237243m8hsa-miR-25brainCAUUGCACUUGUCUCGGUCUGA
hsa-miR-32UAUUGCACAUUACUAAGUUGC
hsa-miR-92UAUUGCACUUGUCCCGGCCUG
hsa-miR-367AAUUGCACUUUAGCAAUGGUGA
hsa-miR-92bSZUAUUGCACUCGUCCCGGCCUC
miR-363236242m8hsa-miR-363AUUGCACGGUAUCCAUCUGUAA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.