Gene Page: USP39

Summary
GeneID  10713
Symbol  USP39
Synonyms  CGI-21|HSPC332|MGC75069|SAD1
Description  ubiquitin specific peptidase 39
See related  HGNC:20071|MIM:611594|Ensembl:ENSG00000168883|HPRD:07165|
Locus tag  -
Gene type  protein-coding
Map location  2p11.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0004 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
SASH30.580.48
CD680.550.47
HCK0.550.46
SYK0.530.46
FOLR20.520.41
NCKAP1L0.520.48
ITGB20.510.49
CYTH40.490.44
SIGLEC70.480.34
CD370.480.43
Top 10 negatively co-expressed genes
AF347015.18-0.19-0.17
MT-CO2-0.18-0.15
AC010300.1-0.18-0.15
NOSTRIN-0.18-0.12
EDN1-0.17-0.06
CXCL2-0.17-0.13
ANP32C-0.17-0.12
F2RL3-0.17-0.08
IL32-0.16-0.13
AF347015.26-0.16-0.13
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI17353931 
GO:0004221ubiquitin thiolesterase activityIEA-
GO:0008270zinc ion bindingIEA-
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000245spliceosome assemblyTAS10022888 
GO:0006397mRNA processingTAS10022888 
GO:0008380RNA splicingTAS10022888 
GO:0006511ubiquitin-dependent protein catabolic processIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005622intracellularIEA-
GO:0005634nucleusIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CD2BP2FWP010 | LIN1 | Snu40 | U5-52KCD2 (cytoplasmic tail) binding protein 2Affinity Capture-MSBioGRID17353931 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_SPLICEOSOME 12872All SZGR genes in this pathway
NAKAMURA_CANCER_MICROENVIRONMENT_DN 4629All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP 1278748All SZGR genes in this pathway
STARK_PREFRONTAL_CORTEX_22Q11_DELETION_DN 517309All SZGR genes in this pathway
MANALO_HYPOXIA_DN 289166All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS 882572All SZGR genes in this pathway
DOUGLAS_BMI1_TARGETS_UP 566371All SZGR genes in this pathway
WONG_PROTEASOME_GENE_MODULE 4935All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_WITH_H3K9ME3_DN 12071All SZGR genes in this pathway
KUROKAWA_LIVER_CANCER_EARLY_RECURRENCE_UP 129All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_11 10368All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
LEE_BMP2_TARGETS_DN 882538All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-299-5p4694751Ahsa-miR-299-5pUGGUUUACCGUCCCACAUACAU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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