Gene Page: MASP2

Summary
GeneID  10747
Symbol  MASP2
Synonyms  MAP19|MASP-2|sMAP
Description  mannan-binding lectin serine peptidase 2
See related  HGNC:6902|MIM:605102|Ensembl:ENSG00000009724|HPRD:05484|
Locus tag  -
Gene type  protein-coding
Map location  1p36.3-p36.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ROCK20.800.78
EEA10.800.77
PTPN110.790.78
SECISBP2L0.790.77
LNPEP0.780.79
DMXL10.780.78
RAB11FIP20.780.76
PPP1R9A0.780.77
ZFP1060.770.77
CDC42BPA0.770.75
Top 10 negatively co-expressed genes
EFEMP2-0.43-0.45
NUDT8-0.42-0.43
BTBD17-0.40-0.46
DBI-0.38-0.43
KIF19-0.38-0.42
AC006276.2-0.37-0.34
CST3-0.37-0.33
EIF4EBP3-0.37-0.39
RAB34-0.36-0.39
NME4-0.35-0.41
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004252serine-type endopeptidase activityTASglutamate (GO term level: 7)9087411 
GO:0005509calcium ion bindingIEA-
GO:0008233peptidase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0001867complement activation, lectin pathwayEXP11532276 
GO:0006508proteolysisIEA-
GO:0006958complement activation, classical pathwayIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionEXP10639434 |10925294 
GO:0005576extracellular regionIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
FCN2EBP-37 | FCNL | P35 | ficolin-2ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)-HPRD,BioGRID12421953 
MASP1CRARF | CRARF1 | DKFZp686I01199 | FLJ26383 | MASP | MGC126283 | MGC126284 | PRSS5 | RaRFmannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)Affinity Capture-WesternBioGRID10878362 
MBL2COLEC1 | HSMBPC | MBL | MBP | MBP1 | MGC116832 | MGC116833mannose-binding lectin (protein C) 2, soluble (opsonic defect)-HPRD,BioGRID10878362 
SERPING1C1IN | C1INH | C1NH | HAE1 | HAE2serpin peptidase inhibitor, clade G (C1 inhibitor), member 1-HPRD,BioGRID10946292 
 


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