Gene Page: ADAP1

Summary
GeneID  11033
Symbol  ADAP1
Synonyms  CENTA1|GCS1L|p42IP4
Description  ArfGAP with dual PH domains 1
See related  HGNC:16486|MIM:608114|Ensembl:ENSG00000105963|HPRD:09733|
Locus tag  -
Gene type  protein-coding
Map location  7p22.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0139 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
IFT800.800.79
TAX1BP10.790.79
USO10.790.77
AGGF10.770.76
UBLCP10.770.77
MTIF20.770.77
SYAP10.770.78
DNAJC240.760.75
USP80.760.77
SDCCAG10.760.75
Top 10 negatively co-expressed genes
ENHO-0.44-0.43
AF347015.21-0.43-0.25
AF347015.2-0.42-0.30
CLDN5-0.41-0.41
MT-CO2-0.40-0.31
PLA2G5-0.40-0.27
NUDT8-0.40-0.41
IL32-0.39-0.30
PLAC9-0.39-0.31
AF347015.31-0.39-0.32
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI12893243 
GO:0008270zinc ion bindingIEA-
GO:0008060ARF GTPase activator activityIDA10333475 |10448098 
GO:0046872metal ion bindingIEA-
GO:0043533inositol 1,3,4,5 tetrakisphosphate bindingTAS12018390 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007166cell surface receptor linked signal transductionTAS10333475 
GO:0043087regulation of GTPase activityIMP10333475 
GO:0032312regulation of ARF GTPase activityIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIDA10333475 |10448098 
GO:0005737cytoplasmIDA10333475 |10448098 
GO:0005886plasma membraneIDA10333475 |10448098 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ANP32AC15orf1 | I1PP2A | LANP | MAPM | MGC119787 | MGC150373 | PHAP1 | PHAPI | PP32acidic (leucine-rich) nuclear phosphoprotein 32 family, member A-HPRD,BioGRID12565890 
AP3B2DKFZp686D17136 | NAPTBadaptor-related protein complex 3, beta 2 subunit-HPRD12565890 
CSNK1A1CK1 | HLCDGP1 | PRO2975casein kinase 1, alpha 1-HPRD,BioGRID11278595 
NCLC23 | FLJ45706nucleolin-HPRD,BioGRID12565890 
PIK3CAMGC142161 | MGC142163 | PI3K | p110-alphaphosphoinositide-3-kinase, catalytic, alpha polypeptideBiochemical Activity
Reconstituted Complex		BioGRID12893243 
PRKCAAAG6 | MGC129900 | MGC129901 | PKC-alpha | PKCA | PRKACAprotein kinase C, alpha-HPRD12893243 
PRKCEMGC125656 | MGC125657 | PKCE | nPKC-epsilonprotein kinase C, epsilonBiochemical ActivityBioGRID12893243 
PRKCIDXS1179E | MGC26534 | PKCI | nPKC-iotaprotein kinase C, iotaAffinity Capture-Western
Reconstituted Complex		BioGRID12893243 
PRKCZPKC-ZETA | PKC2protein kinase C, zeta-HPRD,BioGRID12893243 
PRKD1PKC-MU | PKCM | PKD | PRKCMprotein kinase D1-HPRD,BioGRID12893243 
PSME3Ki | PA28-gamma | PA28G | REG-GAMMAproteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)Two-hybridBioGRID16169070 
PURAPUR-ALPHA | PUR1 | PURALPHApurine-rich element binding protein A-HPRD12565890 
RPS9-ribosomal protein S9-HPRD12565890 
SF3A3PRP9 | PRPF9 | SAP61 | SF3a60splicing factor 3a, subunit 3, 60kDa-HPRD12565890 
SFRS2PR264 | SC-35 | SC35 | SFRS2A | SRp30bsplicing factor, arginine/serine-rich 2-HPRD12565890 
SUB1MGC102747 | P15 | PC4 | p14SUB1 homolog (S. cerevisiae)-HPRD12565890 
 


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