Gene Page: DSTN

Summary
GeneID  11034
Symbol  DSTN
Synonyms  ACTDP|ADF|bA462D18.2
Description  destrin (actin depolymerizing factor)
See related  HGNC:15750|MIM:609114|Ensembl:ENSG00000125868|HPRD:16446|
Locus tag  -
Gene type  protein-coding
Map location  20p12.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.046 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
SGTA0.880.88
TMEM1800.880.87
RNF1260.860.88
VAC140.850.84
DECR20.840.84
ARMC50.840.85
LRRC240.840.87
WDR180.840.87
GLTPD10.840.87
MED160.840.86
Top 10 negatively co-expressed genes
AF347015.8-0.70-0.70
AF347015.27-0.70-0.70
AF347015.33-0.69-0.68
MT-CYB-0.68-0.68
MT-CO2-0.68-0.67
AF347015.31-0.68-0.66
AF347015.15-0.66-0.66
AF347015.21-0.66-0.70
AF347015.26-0.64-0.66
AF347015.2-0.64-0.64
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003779actin bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000910cytokinesisIEA-
GO:0008154actin polymerization or depolymerizationTAS8399167 
GO:0006928cell motionIEA-
GO:0051014actin filament severingTAS8399167 
GO:0030836positive regulation of actin filament depolymerizationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005622intracellularIEA-
GO:0005737cytoplasmIEA-
GO:0030864cortical actin cytoskeletonIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ACTBPS1TP5BP1actin, betaTwo-hybridBioGRID16189514 
ACTG1ACT | ACTG | DFNA20 | DFNA26actin, gamma 1-HPRD8399167 
Two-hybridBioGRID16189514 
RRBP1DKFZp586A1420 | ES/130 | ES130 | FLJ36146 | MGC157720 | MGC157721 | hESribosome binding protein 1 homolog 180kDa (dog)Affinity Capture-MSBioGRID17353931 
SSH1FLJ38102 | KIAA1298 | SSH-1slingshot homolog 1 (Drosophila)Biochemical ActivityBioGRID11832213 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-4952452511Ahsa-miR-495brainAAACAAACAUGGUGCACUUCUUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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