Gene Page: STMN2

Summary
GeneID  11075
Symbol  STMN2
Synonyms  SCG10|SCGN10|SGC10
Description  stathmin-like 2
See related  HGNC:10577|MIM:600621|Ensembl:ENSG00000104435|HPRD:09003|
Locus tag  -
Gene type  protein-coding
Map location  8q21.13
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 3 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
MRPS220.880.87
COMMD80.870.87
RP4-604K5.10.870.85
CCDC1040.860.85
ATP5F10.850.81
COMMD100.850.84
CHMP50.840.80
COPS40.840.84
PSMC60.840.83
TXNDC90.830.82
Top 10 negatively co-expressed genes
TENC1-0.48-0.53
MTSS1L-0.48-0.51
MICALL2-0.46-0.51
FAM38A-0.46-0.47
DOCK6-0.46-0.47
AF347015.18-0.45-0.29
C10orf108-0.45-0.51
AC020763.2-0.44-0.48
C9orf131-0.44-0.50
AC010618.2-0.44-0.50
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI16189514 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0030182neuron differentiationNASneuron (GO term level: 8)-
GO:0007242intracellular signaling cascadeIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0042995cell projectionIEAaxon (GO term level: 4)-
GO:0030426growth coneIEAaxon, dendrite (GO term level: 5)-
GO:0005624membrane fractionNAS-
GO:0005625soluble fractionNAS-
GO:0005737cytoplasmIEA-
GO:0016020membraneIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
EEF1A1CCS-3 | CCS3 | EEF-1 | EEF1A | EF-Tu | EF1A | FLJ25721 | GRAF-1EF | HNGC:16303 | LENG7 | MGC102687 | MGC131894 | MGC16224 | PTI1 | eEF1A-1eukaryotic translation elongation factor 1 alpha 1Two-hybridBioGRID16169070 
GPRASP1GASP | GASP1 | KIAA0443G protein-coupled receptor associated sorting protein 1Two-hybridBioGRID16169070 
MAPK10FLJ12099 | FLJ33785 | JNK3 | JNK3A | MGC50974 | PRKM10 | p493F12 | p54bSAPKmitogen-activated protein kinase 10in vitroBioGRID11718727 
RESTNRSF | XBRRE1-silencing transcription factorNRSF/REST interacts with SCG10 promoter in the region of the NRSE/RE1 (neuron restrictive silencer element).BIND15035981 
RGS20RGSZ1 | ZGAP1regulator of G-protein signaling 20Reconstituted ComplexBioGRID11882662 
RGS6DKFZp313G1241 | FLJ43552 | GAP | MGC142132regulator of G-protein signaling 6Affinity Capture-Western
Two-hybrid		BioGRID12140291 
SMARCA4BAF190 | BRG1 | FLJ39786 | SNF2 | SNF2-BETA | SNF2L4 | SNF2LB | SWI2 | hSNF2bSWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4BRG1 interacts with SCG10 promoter.BIND15035981 
SMARCC2BAF170 | CRACC2 | Rsc8SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2BAF170 interacts with SCG10 promoter.BIND15035981 
TEX11TGC1 | TSGA3testis expressed 11Affinity Capture-Western
Two-hybrid		BioGRID16189514 
TRPC5TRP5transient receptor potential cation channel, subfamily C, member 5Affinity Capture-WesternBioGRID12858178 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
SENESE_HDAC3_TARGETS_UP 501327All SZGR genes in this pathway
LEE_NEURAL_CREST_STEM_CELL_UP 14699All SZGR genes in this pathway
DELYS_THYROID_CANCER_UP 443294All SZGR genes in this pathway
MARKEY_RB1_CHRONIC_LOF_UP 11578All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_DN 164111All SZGR genes in this pathway
COWLING_MYCN_TARGETS 4327All SZGR genes in this pathway
ROPERO_HDAC2_TARGETS 11471All SZGR genes in this pathway
BENPORATH_OCT4_TARGETS 290172All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS 652441All SZGR genes in this pathway
STARK_PREFRONTAL_CORTEX_22Q11_DELETION_DN 517309All SZGR genes in this pathway
NIKOLSKY_BREAST_CANCER_8Q12_Q22_AMPLICON 13282All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_TRANS 185114All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_16HR_DN 8662All SZGR genes in this pathway
MCCLUNG_DELTA_FOSB_TARGETS_2WK 4836All SZGR genes in this pathway
MCCLUNG_CREB1_TARGETS_UP 10072All SZGR genes in this pathway
XU_GH1_AUTOCRINE_TARGETS_UP 268157All SZGR genes in this pathway
HANN_RESISTANCE_TO_BCL2_INHIBITOR_UP 3624All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_DN 435289All SZGR genes in this pathway
WINNEPENNINCKX_MELANOMA_METASTASIS_DN 4626All SZGR genes in this pathway
GYORFFY_DOXORUBICIN_RESISTANCE 5634All SZGR genes in this pathway
MIKKELSEN_NPC_HCP_WITH_H3K27ME3 341243All SZGR genes in this pathway
DASU_IL6_SIGNALING_UP 5944All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP 548370All SZGR genes in this pathway
PASINI_SUZ12_TARGETS_DN 315215All SZGR genes in this pathway
KATSANOU_ELAVL1_TARGETS_DN 14888All SZGR genes in this pathway
SERVITJA_ISLET_HNF1A_TARGETS_UP 163111All SZGR genes in this pathway
PLASARI_TGFB1_TARGETS_10HR_DN 244157All SZGR genes in this pathway
DELACROIX_RAR_BOUND_ES 462273All SZGR genes in this pathway
PEDRIOLI_MIR31_TARGETS_DN 418245All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-34b43491Ahsa-miR-34bUAGGCAGUGUCAUUAGCUGAUUG
miR-369-3p50561Ahsa-miR-369-3pAAUAAUACAUGGUUGAUCUUU
miR-37450571A,m8hsa-miR-374UUAUAAUACAACCUGAUAAGUG
miR-485-3p8591m8hsa-miR-485-3pGUCAUACACGGCUCUCCUCUCU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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