Gene Page: TPPP

Summary
GeneID  11076
Symbol  TPPP
Synonyms  TPPP/p25|TPPP1|p24|p25|p25alpha
Description  tubulin polymerization promoting protein
See related  HGNC:24164|MIM:608773|Ensembl:ENSG00000171368|HPRD:18522|
Locus tag  -
Gene type  protein-coding
Map location  5p15.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
POT10.880.86
PTGES30.860.86
TMEM680.860.83
FBXL50.860.83
MAPKSP10.860.83
BBS100.850.84
C3orf380.850.84
NMD30.850.81
ORC4L0.850.85
UBE2N0.840.82
Top 10 negatively co-expressed genes
AF347015.26-0.70-0.70
MT-CO2-0.70-0.67
AF347015.33-0.69-0.67
AF347015.8-0.68-0.68
AF347015.2-0.67-0.65
MT-CYB-0.67-0.67
AF347015.15-0.67-0.67
AF347015.18-0.65-0.69
AF347015.27-0.62-0.63
TINAGL1-0.61-0.65
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI15590652 
GO:0008017microtubule bindingISS-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0001578microtubule bundle formationISS-
GO:0032273positive regulation of protein polymerizationIDA15590652 
GO:0031334positive regulation of protein complex assemblyISS-
GO:0046785microtubule polymerizationISS-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005625soluble fractionISS-
GO:0048471perinuclear region of cytoplasmIDA15590652 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
GSK3B-glycogen synthase kinase 3 beta-HPRD11781156 
TPPPTPPP/p25 | TPPP1 | p24 | p25 | p25alphatubulin polymerization promoting protein-HPRD11781156 
 
Pathway annotation
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1/2067076m8hsa-miR-1UGGAAUGUAAAGAAGUAUGUA
hsa-miR-206SZUGGAAUGUAAGGAAGUGUGUGG
hsa-miR-613AGGAAUGUUCCUUCUUUGCC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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