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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: MYST2

Summary

GeneID

11143

Symbol

MYST2

Synonyms

HBO1|HBOA|KAT7

Description

MYST histone acetyltransferase 2

Locus tag

Gene type

protein-coding

Map location

17q21.32

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.0949

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0003700

transcription factor activity

IEA

GO:0005515

protein binding

IPI

10930412 |15383276 |16169070

GO:0004406

H3/H4 histone acetyltransferase activity

TAS

10438470

GO:0016740

transferase activity

IEA

GO:0008270

zinc ion binding

IEA

GO:0008415

acyltransferase activity

IEA

GO:0046872

metal ion binding

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006355

regulation of transcription, DNA-dependent

TAS

10438470

GO:0006350

transcription

IEA

GO:0006260

DNA replication

TAS

10438470

GO:0016568

chromatin modification

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005622

intracellular

IEA

GO:0005634

nucleus

TAS

10438470

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
AR	AIS \| DHTR \| HUMARA \| KD \| NR3C4 \| SBMA \| SMAX1 \| TFM	androgen receptor	-	HPRD,BioGRID	10930412
ATN1	B37 \| D12S755E \| DRPLA \| NOD	atrophin 1	Two-hybrid	BioGRID	16169070
C15orf29	FLJ22557 \| MGC117356	chromosome 15 open reading frame 29	Two-hybrid	BioGRID	16169070
C9orf82	FLJ13657 \| RP11-337A23.1	chromosome 9 open reading frame 82	Two-hybrid	BioGRID	16169070
CALCOCO2	MGC17318 \| NDP52	calcium binding and coiled-coil domain 2	Two-hybrid	BioGRID	16189514
CBX8	HPC3 \| PC3 \| RC1	chromobox homolog 8 (Pc class homolog, Drosophila)	Two-hybrid	BioGRID	16169070
CEP70	BITE \| FLJ13036	centrosomal protein 70kDa	Two-hybrid	BioGRID	16189514
DDX11	CHL1 \| CHLR1 \| KRG2 \| MGC133249 \| MGC9335	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae)	Two-hybrid	BioGRID	16169070
DVL3	KIAA0208	dishevelled, dsh homolog 3 (Drosophila)	Two-hybrid	BioGRID	16189514
HOOK2	FLJ26218 \| HK2	hook homolog 2 (Drosophila)	Two-hybrid	BioGRID	16189514
KCTD13	FKSG86 \| PDIP1 \| POLDIP1	potassium channel tetramerisation domain containing 13	Two-hybrid	BioGRID	16189514
ORC1L	HSORC1 \| ORC1 \| PARC1	origin recognition complex, subunit 1-like (yeast)	-	HPRD,BioGRID	10438470
PACSIN1	KIAA1379 \| SDPI	protein kinase C and casein kinase substrate in neurons 1	Two-hybrid	BioGRID	16169070
POLB	MGC125976	polymerase (DNA directed), beta	Two-hybrid	BioGRID	16169070
PPID	CYP-40 \| CYPD \| MGC33096	peptidylprolyl isomerase D	Two-hybrid	BioGRID	16169070
RGL2	HKE1.5 \| KE1.5 \| RAB2L	ral guanine nucleotide dissociation stimulator-like 2	Two-hybrid	BioGRID	16169070
RP4-691N24.1	FLJ11792 \| KIAA0980 \| NLP \| dJ691N24.1	ninein-like	Two-hybrid	BioGRID	16189514
RPS10	MGC88819	ribosomal protein S10	Two-hybrid	BioGRID	16169070
SAT1	DC21 \| KFSD \| SAT \| SSAT \| SSAT-1	spermidine/spermine N1-acetyltransferase 1	Two-hybrid	BioGRID	16169070
SEPT5	CDCREL \| CDCREL-1 \| CDCREL1 \| H5 \| PNUTL1	septin 5	Two-hybrid	BioGRID	16169070
SNAPIN	SNAPAP	SNAP-associated protein	Two-hybrid	BioGRID	16169070
VIM	FLJ36605	vimentin	Two-hybrid	BioGRID	16169070 \|16189514
WDR33	FLJ11294 \| WDC146	WD repeat domain 33	Two-hybrid	BioGRID	16169070
ZBTB8	BOZF1 \| FLJ90065 \| MGC17919	zinc finger and BTB domain containing 8	Two-hybrid	BioGRID	16189514
ZNF165	LD65 \| ZSCAN7	zinc finger protein 165	Two-hybrid	BioGRID	16189514

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
PID_AR_TF_PATHWAY	53	38	All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN	1781	1082	All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_UP	191	128	All SZGR genes in this pathway
RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_MODERATELY_UP	109	69	All SZGR genes in this pathway
BENPORATH_ES_1	379	235	All SZGR genes in this pathway
KAUFFMANN_DNA_REPLICATION_GENES	147	87	All SZGR genes in this pathway
NIKOLSKY_BREAST_CANCER_17Q21_Q25_AMPLICON	335	181	All SZGR genes in this pathway
MARIADASON_RESPONSE_TO_CURCUMIN_SULINDAC_7	19	10	All SZGR genes in this pathway
GAVIN_FOXP3_TARGETS_CLUSTER_P3	160	103	All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_UP	673	430	All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_DN	593	372	All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_DN	591	366	All SZGR genes in this pathway
TOYOTA_TARGETS_OF_MIR34B_AND_MIR34C	463	262	All SZGR genes in this pathway
MUELLER_PLURINET	299	189	All SZGR genes in this pathway
AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_UP	298	174	All SZGR genes in this pathway
HAN_SATB1_TARGETS_UP	395	249	All SZGR genes in this pathway
VERHAAK_GLIOBLASTOMA_PRONEURAL	177	132	All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D	882	506	All SZGR genes in this pathway
DELACROIX_RAR_BOUND_ES	462	273	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-101	275	282	1A,m8	hsa-miR-101	UACAGUACUGUGAUAACUGAAG
miR-124/506	1349	1355	m8	hsa-miR-506	UAAGGCACCCUUCUGAGUAGA
miR-124/506	1349	1355	m8	hsa-miR-124^brain	UAAGGCACGCGGUGAAUGCC
miR-128	1387	1393	m8	hsa-miR-128a	UCACAGUGAACCGGUCUCUUUU
miR-128	1387	1393	m8	hsa-miR-128b	UCACAGUGAACCGGUCUCUUUC
miR-132/212	1452	1458	1A	hsa-miR-212^SZ	UAACAGUCUCCAGUCACGGCC
miR-132/212	1452	1458	1A	hsa-miR-132^brain	UAACAGUCUACAGCCAUGGUCG
miR-134	289	295	m8	hsa-miR-134^brain	UGUGACUGGUUGACCAGAGGG
miR-142-3p	1373	1379	m8	hsa-miR-142-3p	UGUAGUGUUUCCUACUUUAUGGA
miR-144	276	282	1A	hsa-miR-144	UACAGUAUAGAUGAUGUACUAG
miR-148/152	249	255	1A	hsa-miR-148a	UCAGUGCACUACAGAACUUUGU
				hsa-miR-152^brain	UCAGUGCAUGACAGAACUUGGG
				hsa-miR-148b	UCAGUGCAUCACAGAACUUUGU
miR-149	17	23	m8	hsa-miR-149^brain	UCUGGCUCCGUGUCUUCACUCC
miR-335	79	85	m8	hsa-miR-335^brain	UCAAGAGCAAUAACGAAAAAUGU
miR-491	1530	1537	1A,m8	hsa-miR-491^brain	AGUGGGGAACCCUUCCAUGAGGA
miR-539	1212	1218	m8	hsa-miR-539	GGAGAAAUUAUCCUUGGUGUGU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.