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GeneID |
1128
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Symbol |
CHRM1
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Synonyms |
HM1|M1|MGC30125
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Description |
cholinergic receptor, muscarinic 1 |
See related |
HGNC:1950|MIM:118510|Ensembl:ENSG00000168539|HPRD:00338| |
Locus tag |
- |
Gene type |
protein-coding |
Map location |
11q13 |
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Gene set name |
Method of gene set |
Evidence |
Info |
Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenia] | Click to show detail | GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 2 | |
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General Gene Expression (microarray) ? |
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Gene Expression in Brain Regions (new) |
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Top co-expressed genes in Brain Regions (new) |
|
Gene | Pearson's Correlation | Spearman's Correlation | | |
Top 10 positively co-expressed genes |
RGS16 | 0.94 | 0.45 | | |
SUSD2 | 0.93 | -0.06 | | |
EPN3 | 0.92 | 0.32 | | |
GRID2IP | 0.91 | 0.37 | | |
PTPN3 | 0.90 | 0.34 | | |
FAM19A4 | 0.90 | 0.19 | | |
TTC39A | 0.89 | 0.37 | | |
CARD11 | 0.89 | 0.28 | | |
GNG13 | 0.88 | 0.17 | | |
RGS3 | 0.88 | 0.49 | | |
Top 10 negatively co-expressed genes | WDR86 | -0.21 | -0.01 | | |
EMID1 | -0.20 | -0.07 | | |
SLC26A4 | -0.17 | 0.11 | | |
ETV4 | -0.16 | -0.19 | | |
MEIS3P2 | -0.16 | 0.38 | | |
OAF | -0.16 | -0.34 | | |
RGS20 | -0.16 | -0.29 | | |
NPAS1 | -0.16 | 0.06 | | |
TMOD1 | -0.16 | 0.14 | | |
RLBP1 | -0.16 | -0.34 | | |
|
Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0004872 | receptor activity | IEA | | - |
GO:0004981 | muscarinic acetylcholine receptor activity | TAS | | 9614217 |
GO:0004435 | phosphoinositide phospholipase C activity | TAS | | 9614217 |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0007399 | nervous system development | TAS | neurite (GO term level: 5) | 2739737 |
GO:0007205 | activation of protein kinase C activity | TAS | | 9603968 |
GO:0006464 | protein modification process | TAS | | 1411529 |
GO:0007207 | muscarinic acetylcholine receptor, phospholipase C activating pathway | TAS | | 8139539 |
GO:0007213 | acetylcholine receptor signaling, muscarinic pathway | TAS | | 8139539 |
GO:0007165 | signal transduction | TAS | | 3443095 |9614217 |
GO:0008284 | positive regulation of cell proliferation | TAS | | 2739737 |
GO:0040012 | regulation of locomotion | IEA | | - |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0045211 | postsynaptic membrane | IEA | Synap, Neurotransmitter (GO term level: 5) | - |
GO:0045202 | synapse | IEA | neuron, Synap, Neurotransmitter, Glial (GO term level: 2) | - |
GO:0005624 | membrane fraction | TAS | | 7925360 |
GO:0005886 | plasma membrane | TAS | | 7925360 |
GO:0005887 | integral to plasma membrane | TAS | | 8508928 |
GO:0030054 | cell junction | IEA | | - |
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- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
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