Gene Page: CHRM4

Summary
GeneID  1132
Symbol  CHRM4
Synonyms  HM4
Description  cholinergic receptor, muscarinic 4
See related  HGNC:1953|MIM:118495|HPRD:00330|
Locus tag  -
Gene type  protein-coding
Map location  11p12-p11.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenia]Click to show detail
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
STK190.830.79
EVL0.820.79
FBL0.810.78
ZMYND190.800.77
GNB20.790.78
SCMH10.790.80
KLHL220.790.77
DTX10.780.77
ADPRHL20.780.75
MVD0.780.77
Top 10 negatively co-expressed genes
MT-CO2-0.62-0.65
AF347015.27-0.61-0.65
AF347015.8-0.60-0.65
AF347015.31-0.60-0.63
AF347015.21-0.60-0.67
MT-CYB-0.59-0.63
AF347015.33-0.58-0.62
NOSTRIN-0.55-0.59
AF347015.15-0.55-0.62
AF347015.2-0.54-0.62
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004872receptor activityIEA-
GO:0004981muscarinic acetylcholine receptor activityTAS9603968 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007213acetylcholine receptor signaling, muscarinic pathwayTAS3443095 
GO:0008283cell proliferationTAS2739737 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0045211postsynaptic membraneIEASynap, Neurotransmitter (GO term level: 5)-
GO:0045202synapseIEAneuron, Synap, Neurotransmitter, Glial (GO term level: 2)-
GO:0005886plasma membraneTAS3443095 
GO:0005887integral to plasma membraneTAS3037705 
GO:0030054cell junctionIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
EEF1A2EEF1AL | EF-1-alpha-2 | EF1A | FLJ41696 | HS1 | STN | STNLeukaryotic translation elongation factor 1 alpha 2The third intracellular loop of M4 interacts with eEf1A2.BIND12048193 
-HPRD12048193 
GRB2ASH | EGFRBP-GRB2 | Grb3-3 | MST084 | MSTP084growth factor receptor-bound protein 2M4 interacts with Grb2.BIND9843378 
 
Pathway annotation


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