|
|
| GeneID |
1134
|
| Symbol |
CHRNA1
|
| Synonyms |
ACHRA|ACHRD|CHRNA|CMS2A|FCCMS|SCCMS
|
| Description |
cholinergic receptor, nicotinic, alpha 1 (muscle) |
| See related |
HGNC:1955|MIM:100690|Ensembl:ENSG00000138435|HPRD:00007| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
2q24-q32 |
|
| |
|
|
| Gene set name |
Method of gene set |
Evidence |
Info |
| GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 5 | |
|
| |
| General Gene Expression (microarray) ? |
|
 |
| |
| Gene Expression in Brain Regions (new) |
|
| |
| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| KCNC2 | 0.75 | 0.75 | | |
| ANXA6 | 0.73 | 0.77 | | |
| PTHLH | 0.71 | 0.75 | | |
| SIAE | 0.71 | 0.73 | | |
| SSTR3 | 0.70 | 0.77 | | |
| SNX10 | 0.70 | 0.70 | | |
| REEP5 | 0.69 | 0.67 | | |
| RAB37 | 0.69 | 0.74 | | |
| GPR123 | 0.69 | 0.66 | | |
| SGPP2 | 0.69 | 0.69 | | |
Top 10 negatively co-expressed genes | | TUBB2B | -0.43 | -0.56 | | |
| KIAA1949 | -0.43 | -0.46 | | |
| TRAF4 | -0.42 | -0.57 | | |
| FADS2 | -0.42 | -0.51 | | |
| SH3BP2 | -0.42 | -0.59 | | |
| CARHSP1 | -0.42 | -0.60 | | |
| RBMX2 | -0.42 | -0.56 | | |
| TIGD1 | -0.41 | -0.43 | | |
| PDE9A | -0.41 | -0.57 | | |
| ZNF311 | -0.41 | -0.41 | | |
|
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0015464 | acetylcholine receptor activity | TAS | Neurotransmitter (GO term level: 6) | 7619526 |
| GO:0004889 | nicotinic acetylcholine-activated cation-selective channel activity | IMP | | 9221765 |
| GO:0005216 | ion channel activity | TAS | | 6688857 |
| GO:0005230 | extracellular ligand-gated ion channel activity | IEA | | - |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0007274 | neuromuscular synaptic transmission | IMP | neuron, Synap (GO term level: 7) | 9221765 |
| GO:0007528 | neuromuscular junction development | IMP | Synap (GO term level: 10) | 9221765 |
| GO:0007165 | signal transduction | TAS | | 7619526 |
| GO:0006811 | ion transport | IEA | | - |
| GO:0006936 | muscle contraction | TAS | | 7619526 |
| GO:0042391 | regulation of membrane potential | IMP | | 9221765 |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0031594 | neuromuscular junction | IDA | neuron, axon, Synap, Neurotransmitter (GO term level: 3) | 9221765 |
| GO:0005892 | nicotinic acetylcholine-gated receptor-channel complex | TAS | Neurotransmitter (GO term level: 9) | 7619526 |
| GO:0045211 | postsynaptic membrane | IEA | Synap, Neurotransmitter (GO term level: 5) | - |
| GO:0016021 | integral to membrane | IEA | | - |
| GO:0005886 | plasma membrane | IEA | | - |
| GO:0030054 | cell junction | IEA | | - |
| |
|
|
| |
|
|
