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| GeneID |
1135
|
| Symbol |
CHRNA2
|
| Synonyms |
-
|
| Description |
cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| See related |
HGNC:1956|MIM:118502|Ensembl:ENSG00000120903|HPRD:00332| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
8p21 |
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| Gene set name |
Method of gene set |
Evidence |
Info |
| GSMA_I | genome scan meta-analysis | Psr: 0.031 | | | GSMA_IIE | genome scan meta-analysis (European-ancestry samples) | Psr: 0.00057 | | | GSMA_IIA | genome scan meta-analysis (All samples) | Psr: 0.03086 | | | Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia] | Click to show detail | | GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 3 | |
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| General Gene Expression (microarray) ? |
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| Gene Expression in Brain Regions (new) |
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| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| AC005544.1 | 0.86 | 0.85 | | |
| CACNG4 | 0.86 | 0.86 | | |
| FGD1 | 0.85 | 0.88 | | |
| CUL7 | 0.84 | 0.86 | | |
| HCN3 | 0.84 | 0.88 | | |
| IFT140 | 0.84 | 0.85 | | |
| PLEKHG4B | 0.84 | 0.86 | | |
| REC8 | 0.83 | 0.85 | | |
| UBAP2 | 0.83 | 0.85 | | |
| C17orf70 | 0.83 | 0.84 | | |
Top 10 negatively co-expressed genes | | C5orf53 | -0.65 | -0.76 | | |
| HLA-F | -0.64 | -0.74 | | |
| AIFM3 | -0.62 | -0.72 | | |
| S100B | -0.62 | -0.78 | | |
| CA4 | -0.62 | -0.72 | | |
| ALDOC | -0.62 | -0.67 | | |
| AF347015.27 | -0.61 | -0.80 | | |
| AF347015.31 | -0.61 | -0.79 | | |
| PTH1R | -0.61 | -0.69 | | |
| CSRP1 | -0.61 | -0.72 | | |
|
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0015464 | acetylcholine receptor activity | IDA | Neurotransmitter (GO term level: 6) | 8906617 |
| GO:0004889 | nicotinic acetylcholine-activated cation-selective channel activity | IDA | | 8906617 |
| GO:0005216 | ion channel activity | IEA | | - |
| GO:0005230 | extracellular ligand-gated ion channel activity | IEA | | - |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0007165 | signal transduction | IDA | | 8906617 |
| GO:0006811 | ion transport | NAS | | 8906617 |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005892 | nicotinic acetylcholine-gated receptor-channel complex | IDA | Neurotransmitter (GO term level: 9) | 8906617 |
| GO:0045211 | postsynaptic membrane | IEA | Synap, Neurotransmitter (GO term level: 5) | - |
| GO:0045202 | synapse | IEA | neuron, Synap, Neurotransmitter, Glial (GO term level: 2) | - |
| GO:0016021 | integral to membrane | NAS | | 8906617 |
| GO:0005886 | plasma membrane | IEA | | - |
| GO:0030054 | cell junction | IEA | | - |
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