Gene Page: CHRNB1

Summary
GeneID  1140
Symbol  CHRNB1
Synonyms  ACHRB|CHRNB|CMS1D|CMS2A|SCCMS
Description  cholinergic receptor, nicotinic, beta 1 (muscle)
See related  HGNC:1961|MIM:100710|Ensembl:ENSG00000170175|HPRD:01156|
Locus tag  -
Gene type  protein-coding
Map location  17p13.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 6 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0015464acetylcholine receptor activityIMPNeurotransmitter (GO term level: 6)8651643 |8872460 
GO:0004889nicotinic acetylcholine-activated cation-selective channel activityISS-
GO:0004889nicotinic acetylcholine-activated cation-selective channel activityISS-
GO:0005515protein bindingISS-
GO:0005216ion channel activityIEA-
GO:0005230extracellular ligand-gated ion channel activityIEA-
GO:0015267channel activityIMP8872460 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007274neuromuscular synaptic transmissionIMPneuron, Synap (GO term level: 7)8651643 
GO:0007271synaptic transmission, cholinergicIMPneuron, Cholinergic, Synap, Neurotransmitter (GO term level: 7)8872460 
GO:0001941postsynaptic membrane organizationIMPSynap (GO term level: 5)8651643 
GO:0007165signal transductionIMP8872460 
GO:0006812cation transportIMP8872460 
GO:0006936muscle contractionIMP8651643 
GO:0042391regulation of membrane potentialISS-
GO:0050877neurological system processIMP11104662 
GO:0048747muscle fiber developmentIMP8651643 
GO:0035095behavioral response to nicotineIMP16874522 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005892nicotinic acetylcholine-gated receptor-channel complexIMPNeurotransmitter (GO term level: 9)8872460 
GO:0045211postsynaptic membraneIEASynap, Neurotransmitter (GO term level: 5)-
GO:0045202synapseIMPneuron, Synap, Neurotransmitter, Glial (GO term level: 2)8872460 
GO:0005886plasma membraneIEA-
GO:0030054cell junctionIEA-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION 272195All SZGR genes in this pathway
BIOCARTA_ACH_PATHWAY 1613All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_UP 530342All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_UP 536340All SZGR genes in this pathway
LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_UP 181108All SZGR genes in this pathway
GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP 6955All SZGR genes in this pathway
BENPORATH_MYC_TARGETS_WITH_EBOX 230156All SZGR genes in this pathway
FERNANDEZ_BOUND_BY_MYC 182116All SZGR genes in this pathway
REN_ALVEOLAR_RHABDOMYOSARCOMA_UP 9864All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL 254164All SZGR genes in this pathway
DELASERNA_MYOD_TARGETS_UP 8951All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_NHEK_UP 244151All SZGR genes in this pathway
DAZARD_UV_RESPONSE_CLUSTER_G1 6741All SZGR genes in this pathway
HILLION_HMGA1_TARGETS 9071All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_UP 491316All SZGR genes in this pathway
HOFFMANN_PRE_BI_TO_LARGE_PRE_BII_LYMPHOCYTE_DN 7561All SZGR genes in this pathway
DANG_BOUND_BY_MYC 1103714All SZGR genes in this pathway
WONG_ADULT_TISSUE_STEM_MODULE 721492All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_4HR_DN 254158All SZGR genes in this pathway
KOHOUTEK_CCNT1_TARGETS 5026All SZGR genes in this pathway
LE_NEURONAL_DIFFERENTIATION_UP 1813All SZGR genes in this pathway
ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_UP 289184All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway


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