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GeneID |
1145
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Symbol |
CHRNE
|
Synonyms |
ACHRE|CMS1D|CMS1E|CMS2A|FCCMS|SCCMS
|
Description |
cholinergic receptor, nicotinic, epsilon |
See related |
HGNC:1966|MIM:100725|Ensembl:ENSG00000108556|HPRD:00008| |
Locus tag |
- |
Gene type |
protein-coding |
Map location |
17p13-p12 |
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Gene set name |
Method of gene set |
Evidence |
Info |
GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 4 | |
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General Gene Expression (microarray) ? |
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Gene Expression in Brain Regions (new) |
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Top co-expressed genes in Brain Regions (new) |
|
Gene | Pearson's Correlation | Spearman's Correlation | | |
Top 10 positively co-expressed genes |
VANGL2 | 0.91 | 0.77 | | |
MYD88 | 0.90 | 0.78 | | |
VARS | 0.89 | 0.79 | | |
NUP188 | 0.88 | 0.81 | | |
IGFBPL1 | 0.88 | 0.75 | | |
SRC | 0.88 | 0.78 | | |
MED12 | 0.88 | 0.79 | | |
CD276 | 0.87 | 0.80 | | |
ZSWIM5 | 0.87 | 0.77 | | |
NRM | 0.87 | 0.76 | | |
Top 10 negatively co-expressed genes | C5orf53 | -0.59 | -0.70 | | |
FBXO2 | -0.56 | -0.61 | | |
AF347015.27 | -0.55 | -0.74 | | |
HLA-F | -0.55 | -0.60 | | |
AIFM3 | -0.55 | -0.63 | | |
LDHD | -0.54 | -0.61 | | |
AF347015.31 | -0.54 | -0.75 | | |
PTH1R | -0.54 | -0.61 | | |
ALDOC | -0.54 | -0.62 | | |
S100B | -0.54 | -0.69 | | |
|
Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
---|
GO:0015464 | acetylcholine receptor activity | TAS | Neurotransmitter (GO term level: 6) | 8872460 |
GO:0004889 | nicotinic acetylcholine-activated cation-selective channel activity | TAS | | 7531341 |
GO:0005216 | ion channel activity | IEA | | - |
GO:0005230 | extracellular ligand-gated ion channel activity | IEA | | - |
GO:0008324 | cation transmembrane transporter activity | TAS | | 8872460 |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
---|
GO:0007271 | synaptic transmission, cholinergic | TAS | neuron, Cholinergic, Synap, Neurotransmitter (GO term level: 7) | 8872460 |
GO:0007165 | signal transduction | TAS | | 8872460 |
GO:0006811 | ion transport | IEA | | - |
GO:0006936 | muscle contraction | TAS | | 8872460 |
GO:0042391 | regulation of membrane potential | IEA | | - |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
---|
GO:0005892 | nicotinic acetylcholine-gated receptor-channel complex | TAS | Neurotransmitter (GO term level: 9) | 7531341 |
GO:0045211 | postsynaptic membrane | IEA | Synap, Neurotransmitter (GO term level: 5) | - |
GO:0045202 | synapse | IEA | neuron, Synap, Neurotransmitter, Glial (GO term level: 2) | - |
GO:0005886 | plasma membrane | IEA | | - |
GO:0030054 | cell junction | IEA | | - |
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- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
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