Gene Page: CHRNE

Summary
GeneID  1145
Symbol  CHRNE
Synonyms  ACHRE|CMS1D|CMS1E|CMS2A|FCCMS|SCCMS
Description  cholinergic receptor, nicotinic, epsilon
See related  HGNC:1966|MIM:100725|Ensembl:ENSG00000108556|HPRD:00008|
Locus tag  -
Gene type  protein-coding
Map location  17p13-p12
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 4 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
VANGL20.910.77
MYD880.900.78
VARS0.890.79
NUP1880.880.81
IGFBPL10.880.75
SRC0.880.78
MED120.880.79
CD2760.870.80
ZSWIM50.870.77
NRM0.870.76
Top 10 negatively co-expressed genes
C5orf53-0.59-0.70
FBXO2-0.56-0.61
AF347015.27-0.55-0.74
HLA-F-0.55-0.60
AIFM3-0.55-0.63
LDHD-0.54-0.61
AF347015.31-0.54-0.75
PTH1R-0.54-0.61
ALDOC-0.54-0.62
S100B-0.54-0.69
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0015464acetylcholine receptor activityTASNeurotransmitter (GO term level: 6)8872460 
GO:0004889nicotinic acetylcholine-activated cation-selective channel activityTAS7531341 
GO:0005216ion channel activityIEA-
GO:0005230extracellular ligand-gated ion channel activityIEA-
GO:0008324cation transmembrane transporter activityTAS8872460 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007271synaptic transmission, cholinergicTASneuron, Cholinergic, Synap, Neurotransmitter (GO term level: 7)8872460 
GO:0007165signal transductionTAS8872460 
GO:0006811ion transportIEA-
GO:0006936muscle contractionTAS8872460 
GO:0042391regulation of membrane potentialIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005892nicotinic acetylcholine-gated receptor-channel complexTASNeurotransmitter (GO term level: 9)7531341 
GO:0045211postsynaptic membraneIEASynap, Neurotransmitter (GO term level: 5)-
GO:0045202synapseIEAneuron, Synap, Neurotransmitter, Glial (GO term level: 2)-
GO:0005886plasma membraneIEA-
GO:0030054cell junctionIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CHRNA1ACHRA | ACHRD | CHRNA | CMS2A | FCCMS | SCCMScholinergic receptor, nicotinic, alpha 1 (muscle)-HPRD,BioGRID1712080 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-142-3p7257311Ahsa-miR-142-3pUGUAGUGUUUCCUACUUUAUGGA
miR-15/16/195/424/497771777m8hsa-miR-15abrainUAGCAGCACAUAAUGGUUUGUG
hsa-miR-16brainUAGCAGCACGUAAAUAUUGGCG
hsa-miR-15bbrainUAGCAGCACAUCAUGGUUUACA
hsa-miR-195SZUAGCAGCACAGAAAUAUUGGC
hsa-miR-424CAGCAGCAAUUCAUGUUUUGAA
hsa-miR-497CAGCAGCACACUGUGGUUUGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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