Gene Page: CHRNG

Summary
GeneID  1146
Symbol  CHRNG
Synonyms  ACHRG|MGC133376
Description  cholinergic receptor, nicotinic, gamma
See related  HGNC:1967|MIM:100730|Ensembl:ENSG00000196811|HPRD:00009|
Locus tag  -
Gene type  protein-coding
Map location  2q33-q34
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 3 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
EBP0.910.92
HTRA20.910.91
CHCHD60.910.90
TRAPPC40.900.89
EIF60.900.93
RRP90.890.91
VPS280.890.91
SAC3D10.880.91
WDR540.880.91
ACTL6B0.880.88
Top 10 negatively co-expressed genes
AF347015.33-0.70-0.77
AF347015.8-0.70-0.77
AF347015.27-0.69-0.76
MT-CO2-0.69-0.74
MT-CYB-0.68-0.76
AF347015.15-0.68-0.77
AF347015.26-0.68-0.80
AF347015.2-0.67-0.78
AF347015.31-0.66-0.72
AF347015.9-0.62-0.74
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0030594neurotransmitter receptor activityIEANeurotransmitter (GO term level: 5)-
GO:0015464acetylcholine receptor activityTASNeurotransmitter (GO term level: 6)3967651 
GO:0004889nicotinic acetylcholine-activated cation-selective channel activityIEA-
GO:0005216ion channel activityIEA-
GO:0005230extracellular ligand-gated ion channel activityIEA-
GO:0015267channel activityTAS3967651 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007165signal transductionTAS3967651 
GO:0006811ion transportIEA-
GO:0006936muscle contractionTAS8040310 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0045211postsynaptic membraneIEASynap, Neurotransmitter (GO term level: 5)-
GO:0045202synapseIEAneuron, Synap, Neurotransmitter, Glial (GO term level: 2)-
GO:0016021integral to membraneIEA-
GO:0005886plasma membraneIEA-
GO:0005887integral to plasma membraneTAS3967651 
GO:0030054cell junctionIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CHRNA1ACHRA | ACHRD | CHRNA | CMS2A | FCCMS | SCCMScholinergic receptor, nicotinic, alpha 1 (muscle)-HPRD,BioGRID7695910 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION 272195All SZGR genes in this pathway
BIOCARTA_ACH_PATHWAY 1613All SZGR genes in this pathway
REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES 186155All SZGR genes in this pathway
REACTOME_NEURONAL_SYSTEM 279221All SZGR genes in this pathway
REACTOME_NEUROTRANSMITTER_RECEPTOR_BINDING_AND_DOWNSTREAM_TRANSMISSION_IN_THE_POSTSYNAPTIC_CELL 137110All SZGR genes in this pathway
REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS 1613All SZGR genes in this pathway
REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS 1210All SZGR genes in this pathway
CHESLER_BRAIN_D6MIT150_QTL_TRANS 97All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS 882572All SZGR genes in this pathway
SANSOM_APC_TARGETS_DN 366238All SZGR genes in this pathway
KAYO_AGING_MUSCLE_UP 244165All SZGR genes in this pathway
DELASERNA_MYOD_TARGETS_UP 8951All SZGR genes in this pathway
BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_48HR_DN 161105All SZGR genes in this pathway
GRADE_COLON_CANCER_UP 871505All SZGR genes in this pathway
MIKKELSEN_MCV6_ICP_WITH_H3K27ME3 7446All SZGR genes in this pathway
MIKKELSEN_MEF_ICP_WITH_H3K27ME3 206108All SZGR genes in this pathway
MIKKELSEN_ES_ICP_WITH_H3K4ME3 718401All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_DN 841431All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_D 280158All SZGR genes in this pathway
WANG_NFKB_TARGETS 2515All SZGR genes in this pathway


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