Gene Page: APOA5

Summary
GeneID  116519
Symbol  APOA5
Synonyms  APOA-V|APOAV|MGC126836|MGC126838|RAP3
Description  apolipoprotein A-V
See related  HGNC:17288|MIM:606368|Ensembl:ENSG00000110243|HPRD:06966|
Locus tag  -
Gene type  protein-coding
Map location  11q23
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.006 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005319lipid transporter activityIEA-
GO:0008201heparin bindingIDA15878877 
GO:0008201heparin bindingIDA17326667 
GO:0017129triglyceride bindingIEA-
GO:0031210phosphatidylcholine bindingIDA16806135 
GO:0019899enzyme bindingIDA15178420 
GO:0050750low-density lipoprotein receptor bindingIPI17326667 
GO:0060229lipase activator activityIMP15178420 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006869lipid transportIEA-
GO:0042246tissue regenerationIEP11577099 
GO:0051006positive regulation of lipoprotein lipase activityIDA15178420 |16806135 
GO:0042159lipoprotein catabolic processIEA-
GO:0019433triacylglycerol catabolic processIMP15178420 
GO:0050996positive regulation of lipid catabolic processIDA16806135 
GO:0055090acylglycerol homeostasisIDA11588264 
GO:0055090acylglycerol homeostasisIMP15178420 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIDA11577099 
GO:0034364high-density lipoprotein particleIDA15528295 
GO:0034362low-density lipoprotein particleIDA15528295 
GO:0034361very-low-density lipoprotein particleIDA15528295 
GO:0042627chylomicronIDA15528295 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_PPAR_SIGNALING_PATHWAY 6947All SZGR genes in this pathway
REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION 10472All SZGR genes in this pathway
REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 478302All SZGR genes in this pathway
REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM 168115All SZGR genes in this pathway
REACTOME_LIPID_DIGESTION_MOBILIZATION_AND_TRANSPORT 4637All SZGR genes in this pathway
REACTOME_LIPOPROTEIN_METABOLISM 2824All SZGR genes in this pathway
REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT 1615All SZGR genes in this pathway
UEDA_PERIFERAL_CLOCK 169111All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR 681420All SZGR genes in this pathway
BOCHKIS_FOXA2_TARGETS 425261All SZGR genes in this pathway
LEE_LIVER_CANCER_SURVIVAL_UP 185112All SZGR genes in this pathway
CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_DN 17997All SZGR genes in this pathway
YAMASHITA_LIVER_CANCER_STEM_CELL_DN 7651All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3K27ME3 590403All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_2 8650All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A 898516All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-245359m8hsa-miR-24SZUGGCUCAGUUCAGCAGGAACAG
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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