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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: CLTC

Summary

GeneID

1213

Symbol

CLTC

Synonyms

CHC|CHC17|CLH-17|CLTCL2|Hc|KIAA0034

Description

clathrin, heavy chain (Hc)

Locus tag

Gene type

protein-coding

Map location

17q11-qter

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.0262

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005515

protein binding

IPI

11799118 |17220478 |17353931

GO:0005198

structural molecule activity

NAS

1765375

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006886

intracellular protein transport

NAS

1765375

GO:0016192

vesicle-mediated transport

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005886

plasma membrane

EXP

10567358 |11157096

GO:0030132

clathrin coat of coated pit

IEA

GO:0030130

clathrin coat of trans-Golgi network vesicle

IEA

GO:0042470

melanosome

IEA

GO:0031410

cytoplasmic vesicle

IEA

GO:0030659

cytoplasmic vesicle membrane

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
AMPH	AMPH1	amphiphysin	-	HPRD	9195986 \|9280305 \|9603201
AMPH	AMPH1	amphiphysin	in vitro in vivo Reconstituted Complex	BioGRID	9195986 \|9603201
AP1B1	ADTB1 \| AP105A \| BAM22 \| CLAPB2	adaptor-related protein complex 1, beta 1 subunit	-	HPRD,BioGRID	11451993
AP1G1	ADTG \| CLAPG1 \| MGC18255	adaptor-related protein complex 1, gamma 1 subunit	-	HPRD,BioGRID	11451993
AP2A2	ADTAB \| CLAPA2 \| HIP9 \| HYPJ	adaptor-related protein complex 2, alpha 2 subunit	Reconstituted Complex	BioGRID	9280305
AP3B2	DKFZp686D17136 \| NAPTB	adaptor-related protein complex 3, beta 2 subunit	Reconstituted Complex	BioGRID	9545220
ARMCX3	ALEX3 \| DKFZp781N1954 \| KIAA0443 \| MGC12199 \| dJ545K15.2	armadillo repeat containing, X-linked 3	Two-hybrid	BioGRID	16169070
ARR3	ARRX	arrestin 3, retinal (X-arrestin)	-	HPRD	9827808
ARRB1	ARB1 \| ARR1	arrestin, beta 1	-	HPRD	9827808
ARRB2	ARB2 \| ARR2 \| BARR2 \| DKFZp686L0365	arrestin, beta 2	-	HPRD	10097102
C10orf88	FLJ13490	chromosome 10 open reading frame 88	Two-hybrid	BioGRID	16169070
CLINT1	CLINT \| ENTH \| EPN4 \| EPNR \| EPSINR \| FLJ46753 \| KIAA0171	clathrin interactor 1	-	HPRD,BioGRID	12429846
CLTA	LCA	clathrin, light chain (Lca)	-	HPRD,BioGRID	2406259 \|12426379
CLTB	LCB	clathrin, light chain (Lcb)	-	HPRD,BioGRID	10360576 \|12426379
CLTC	CHC \| CHC17 \| CLH-17 \| CLTCL2 \| Hc \| KIAA0034	clathrin, heavy chain (Hc)	-	HPRD,BioGRID	12426379
DNAJC6	DJC6 \| KIAA0473 \| MGC129914 \| MGC129915 \| MGC48436	DnaJ (Hsp40) homolog, subfamily C, member 6	-	HPRD	11470803
DNAJC6	DJC6 \| KIAA0473 \| MGC129914 \| MGC129915 \| MGC48436	DnaJ (Hsp40) homolog, subfamily C, member 6	Reconstituted Complex	BioGRID	12732633
EHD1	FLJ42622 \| FLJ44618 \| H-PAST \| HPAST1 \| PAST \| PAST1	EH-domain containing 1	Reconstituted Complex	BioGRID	11423532
EPN1	-	epsin 1	-	HPRD,BioGRID	10692452
GAK	FLJ16629 \| FLJ40395 \| MGC99654	cyclin G associated kinase	-	HPRD	12732633
GGA1	-	golgi associated, gamma adaptin ear containing, ARF binding protein 1	-	HPRD,BioGRID	11301005
GGA2	FLJ20966 \| KIAA1080 \| VEAR	golgi associated, gamma adaptin ear containing, ARF binding protein 2	-	HPRD,BioGRID	11301005 \|11387476
GGA3	KIAA0154	golgi associated, gamma adaptin ear containing, ARF binding protein 3	-	HPRD,BioGRID	11301005
GRIN1	NMDA1 \| NMDAR1 \| NR1	glutamate receptor, ionotropic, N-methyl D-aspartate 1	-	HPRD	10862698
HGS	HRS \| ZFYVE8	hepatocyte growth factor-regulated tyrosine kinase substrate	-	HPRD,BioGRID	11532964
HIP1	ILWEQ \| MGC126506	huntingtin interacting protein 1	HIP1 interacts with Clathrin-HC (Clathrin heavy chain).	BIND	11517213
HIP1	ILWEQ \| MGC126506	huntingtin interacting protein 1	-	HPRD,BioGRID	11532990
HIP1R	FLJ14000 \| FLJ27022 \| HIP12 \| HIP3 \| ILWEQ \| KIAA0655 \| MGC47513	huntingtin interacting protein 1 related	-	HPRD	11889126
IKBKE	IKK-i \| IKKE \| IKKI \| KIAA0151 \| MGC125294 \| MGC125295 \| MGC125297	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	Affinity Capture-MS	BioGRID	17353931
KIT	C-Kit \| CD117 \| PBT \| SCFR	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	-	HPRD,BioGRID	10477727
LDLRAP1	ARH \| ARH1 \| ARH2 \| DKFZp586D0624 \| FHCB1 \| FHCB2 \| MGC34705	low density lipoprotein receptor adaptor protein 1	-	HPRD,BioGRID	12221107
MAP3K10	MLK2 \| MST	mitogen-activated protein kinase kinase kinase 10	-	HPRD,BioGRID	12105200
MAP3K7	TAK1 \| TGF1a	mitogen-activated protein kinase kinase kinase 7	-	HPRD	14743216
MAP3K7IP2	FLJ21885 \| KIAA0733 \| TAB2	mitogen-activated protein kinase kinase kinase 7 interacting protein 2	-	HPRD	14743216
MCC	DKFZp762O1615 \| FLJ38893 \| FLJ46755 \| MCC1	mutated in colorectal cancers	Affinity Capture-MS	BioGRID	17353931
NCALD	MGC33870 \| MGC74858	neurocalcin delta	-	HPRD	11964161
PICALM	CALM \| CLTH \| LAP	phosphatidylinositol binding clathrin assembly protein	Affinity Capture-Western Reconstituted Complex	BioGRID	10436022
SNX5	FLJ10931	sorting nexin 5	Two-hybrid	BioGRID	15133132
SNX9	MST155 \| MSTP155 \| SDP1 \| SH3PX1 \| SH3PXD3A \| WISP	sorting nexin 9	-	HPRD,BioGRID	11799118 \|12952949
TFE3	RCCP2 \| TFEA \| bHLHe33	transcription factor binding to IGHM enhancer 3	Affinity Capture-MS	BioGRID	17353931
TNK2	ACK \| ACK1 \| FLJ44758 \| FLJ45547 \| p21cdc42Hs	tyrosine kinase, non-receptor, 2	Reconstituted Complex	BioGRID	11278436
TOM1	FLJ33404	target of myb1 (chicken)	-	HPRD,BioGRID	14563850
TRADD	Hs.89862 \| MGC11078	TNFRSF1A-associated via death domain	-	HPRD	14743216
VCL	CMD1W \| MVCL	vinculin	-	HPRD,BioGRID	8276759

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-1/206	705	711	1A	hsa-miR-1	UGGAAUGUAAAGAAGUAUGUA
				hsa-miR-206^SZ	UGGAAUGUAAGGAAGUGUGUGG
				hsa-miR-613	AGGAAUGUUCCUUCUUUGCC
				hsa-miR-1	UGGAAUGUAAAGAAGUAUGUA
				hsa-miR-206^SZ	UGGAAUGUAAGGAAGUGUGUGG
				hsa-miR-613	AGGAAUGUUCCUUCUUUGCC
miR-130/301	306	312	m8	hsa-miR-130a^brain	CAGUGCAAUGUUAAAAGGGCAU
				hsa-miR-301	CAGUGCAAUAGUAUUGUCAAAGC
				hsa-miR-130b^brain	CAGUGCAAUGAUGAAAGGGCAU
				hsa-miR-454-3p	UAGUGCAAUAUUGCUUAUAGGGUUU
miR-133	700	706	m8	hsa-miR-133a	UUGGUCCCCUUCAACCAGCUGU
miR-133	700	706	m8	hsa-miR-133b	UUGGUCCCCUUCAACCAGCUA
miR-153	595	601	m8	hsa-miR-153	UUGCAUAGUCACAAAAGUGA
miR-19	305	311	m8	hsa-miR-19a	UGUGCAAAUCUAUGCAAAACUGA
miR-19	305	311	m8	hsa-miR-19b	UGUGCAAAUCCAUGCAAAACUGA
miR-205	113	120	1A,m8	hsa-miR-205	UCCUUCAUUCCACCGGAGUCUG
miR-26	1232	1238	1A	hsa-miR-26a^brain	UUCAAGUAAUCCAGGAUAGGC
miR-26	1232	1238	1A	hsa-miR-26b^SZ	UUCAAGUAAUUCAGGAUAGGUU
miR-382	552	558	m8	hsa-miR-382^brain	GAAGUUGUUCGUGGUGGAUUCG
miR-433-3p	111	117	1A	hsa-miR-433^brain	AUCAUGAUGGGCUCCUCGGUGU
miR-496	369	375	1A	hsa-miR-496	AUUACAUGGCCAAUCUC

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.