Gene Page: ADORA1

Summary
GeneID  134
Symbol  ADORA1
Synonyms  RDC7
Description  adenosine A1 receptor
See related  HGNC:262|MIM:102775|Ensembl:ENSG00000163485|HPRD:00042|
Locus tag  -
Gene type  protein-coding
Map location  1q32.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.1839 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0001609adenosine receptor activity, G-protein coupledIEA-
GO:0004872receptor activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007399nervous system developmentTASneurite (GO term level: 5)8450977 
GO:0007186G-protein coupled receptor protein signaling pathwayIEA-
GO:0007267cell-cell signalingTAS7818494 
GO:0007165signal transductionTAS1530647 
GO:0006954inflammatory responseTAS8360491 
GO:0006909phagocytosisTAS8360491 
GO:0008624induction of apoptosis by extracellular signalsTAS7818494 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005886plasma membraneIEA-
GO:0005887integral to plasma membraneTAS1530647 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ADA-adenosine deaminase-HPRD,BioGRID9247966 |12150791 
DRD1DADR | DRD1Adopamine receptor D1-HPRD,BioGRID10890919 
EPB41L24.1-G | DKFZp781D1972 | DKFZp781H1755erythrocyte membrane protein band 4.1-like 2-HPRD12974671 
GNAI2GIP | GNAI2B | H_LUCA15.1 | H_LUCA16.1guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2-HPRD,BioGRID11369591 
GNAO1DKFZp686O0962 | G-ALPHA-o | GNAOguanine nucleotide binding protein (G protein), alpha activating activity polypeptide O-HPRD10521440 
GNASAHO | C20orf45 | GNAS1 | GPSA | GSA | GSP | MGC33735 | PHP1A | PHP1B | POH | dJ309F20.1.1 | dJ806M20.3.3GNAS complex locus-HPRD10521440 
GRM1GPRC1A | GRM1A | MGLUR1 | MGLUR1A | mGlu1glutamate receptor, metabotropic 1-HPRD,BioGRID11278325 
P2RY1P2Y1purinergic receptor P2Y, G-protein coupled, 1-HPRD,BioGRID11390975 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION 272195All SZGR genes in this pathway
REACTOME_SIGNALING_BY_GPCR 920449All SZGR genes in this pathway
REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS 305177All SZGR genes in this pathway
REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS 168All SZGR genes in this pathway
REACTOME_GPCR_DOWNSTREAM_SIGNALING 805368All SZGR genes in this pathway
REACTOME_G_ALPHA_I_SIGNALLING_EVENTS 195114All SZGR genes in this pathway
REACTOME_GPCR_LIGAND_BINDING 408246All SZGR genes in this pathway
DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_DN 6849All SZGR genes in this pathway
RODRIGUES_NTN1_TARGETS_DN 158102All SZGR genes in this pathway
KIM_WT1_TARGETS_12HR_UP 162116All SZGR genes in this pathway
ELVIDGE_HYPOXIA_DN 14694All SZGR genes in this pathway
ELVIDGE_HYPOXIA_BY_DMOG_DN 5940All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP 722443All SZGR genes in this pathway
DELYS_THYROID_CANCER_UP 443294All SZGR genes in this pathway
DACOSTA_ERCC3_ALLELE_XPCS_VS_TTD_UP 2819All SZGR genes in this pathway
WEIGEL_OXIDATIVE_STRESS_RESPONSE 3528All SZGR genes in this pathway
KAAB_HEART_ATRIUM_VS_VENTRICLE_UP 249170All SZGR genes in this pathway
MCCLUNG_COCAINE_REWARD_5D 7962All SZGR genes in this pathway
BAELDE_DIABETIC_NEPHROPATHY_DN 434302All SZGR genes in this pathway
URS_ADIPOCYTE_DIFFERENTIATION_DN 3020All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4 307185All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3 142103All SZGR genes in this pathway
MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3 210148All SZGR genes in this pathway
SERVITJA_LIVER_HNF1A_TARGETS_UP 13596All SZGR genes in this pathway


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