Gene Page: CRHR2

Summary
GeneID  1395
Symbol  CRHR2
Synonyms  CRFR2
Description  corticotropin releasing hormone receptor 2
See related  HGNC:2358|MIM:602034|Ensembl:ENSG00000106113|HPRD:03614|
Locus tag  -
Gene type  protein-coding
Map location  7p15.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
DBX20.730.63
TNNI30.720.62
BARX20.670.66
FCRLA0.630.58
CPE0.630.61
HNMT0.630.67
LIX10.620.60
CTSL20.600.36
PON20.590.59
SLC15A20.590.61
Top 10 negatively co-expressed genes
UNC84B-0.36-0.43
GAB2-0.35-0.50
NDRG1-0.34-0.44
FAM124A-0.34-0.45
AC005035.1-0.33-0.52
MAP4K4-0.33-0.50
HIP1R-0.33-0.51
KIAA1598-0.33-0.45
RFFL-0.32-0.39
PHLDB1-0.31-0.42
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004872receptor activityIEA-
GO:0004930G-protein coupled receptor activityIEA-
GO:0015056corticotrophin-releasing factor receptor activityTAS9717834 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007188G-protein signaling, coupled to cAMP nucleotide second messengerTAS8536644 
GO:0007186G-protein coupled receptor protein signaling pathwayIEA-
GO:0007165signal transductionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005886plasma membraneTAS8536644 
GO:0005887integral to plasma membraneTAS8536644 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CRHCRFcorticotropin releasing hormone-HPRD,BioGRID8243338 
UCNMGC129974 | MGC129975 | UI | UROCurocortin-HPRD8612563 |9423932 
|11416224 
-HPRD11416224 
UCN3MGC119002 | SCP | SPC | UCNIIIurocortin 3 (stresscopin)-HPRD11416224 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION 272195All SZGR genes in this pathway
REACTOME_SIGNALING_BY_GPCR 920449All SZGR genes in this pathway
REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS 8858All SZGR genes in this pathway
REACTOME_GPCR_DOWNSTREAM_SIGNALING 805368All SZGR genes in this pathway
REACTOME_G_ALPHA_S_SIGNALLING_EVENTS 12182All SZGR genes in this pathway
REACTOME_GPCR_LIGAND_BINDING 408246All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_DN 234147All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_UP 13493All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
SCHLESINGER_H3K27ME3_IN_NORMAL_AND_METHYLATED_IN_CANCER 2821All SZGR genes in this pathway
PENG_RAPAMYCIN_RESPONSE_UP 203130All SZGR genes in this pathway
KAYO_AGING_MUSCLE_UP 244165All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_DN 504323All SZGR genes in this pathway
XU_GH1_EXOGENOUS_TARGETS_UP 8550All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR 681420All SZGR genes in this pathway
XU_GH1_AUTOCRINE_TARGETS_UP 268157All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_DN 8859All SZGR genes in this pathway


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.