Gene Page: ADORA3

Summary
GeneID  140
Symbol  ADORA3
Synonyms  A3AR|AD026|bA552M11.5
Description  adenosine A3 receptor
See related  HGNC:268|MIM:600445|Ensembl:ENSG00000121933|HPRD:08984|HPRD:12424|
Locus tag  RP11-552M11.7
Gene type  protein-coding
Map location  1p13.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0235 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
HEATR5A0.810.76
SEPT100.780.72
SEPT20.780.72
SALL10.760.80
CTNNA10.760.66
RFTN20.760.76
MSN0.760.67
ARHGEF60.750.76
NOTCH20.750.76
ITGB10.740.71
Top 10 negatively co-expressed genes
SLC26A4-0.31-0.28
DDTL-0.28-0.25
RPL9-0.28-0.32
A1BG-0.27-0.30
NANOS3-0.27-0.29
NDUFB1-0.27-0.22
TTC9B-0.27-0.24
UQCR-0.26-0.28
C17orf37-0.26-0.28
USMG5-0.26-0.20
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0001609adenosine receptor activity, G-protein coupledIEA-
GO:0004872receptor activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007190activation of adenylate cyclase activityTAS9380026 
GO:0007186G-protein coupled receptor protein signaling pathwayIEA-
GO:0007165signal transductionTAS8399349 |9380026 
GO:0008016regulation of heart contractionTAS9837869 
GO:0006954inflammatory responseTAS9164961 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005886plasma membraneIEA-
GO:0005887integral to plasma membraneTAS8399349 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION 272195All SZGR genes in this pathway
REACTOME_SIGNALING_BY_GPCR 920449All SZGR genes in this pathway
REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS 305177All SZGR genes in this pathway
REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS 168All SZGR genes in this pathway
REACTOME_GPCR_DOWNSTREAM_SIGNALING 805368All SZGR genes in this pathway
REACTOME_G_ALPHA_I_SIGNALLING_EVENTS 195114All SZGR genes in this pathway
REACTOME_GPCR_LIGAND_BINDING 408246All SZGR genes in this pathway
SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP 351230All SZGR genes in this pathway
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_DN 205127All SZGR genes in this pathway
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_DN 14383All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_DN 1375806All SZGR genes in this pathway
DELYS_THYROID_CANCER_UP 443294All SZGR genes in this pathway
TSAI_RESPONSE_TO_IONIZING_RADIATION 149101All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_PLASMABLAST_UP 398262All SZGR genes in this pathway
NAKAJIMA_EOSINOPHIL 3020All SZGR genes in this pathway
NIELSEN_SCHWANNOMA_UP 1816All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN 911527All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP 783442All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A12 317177All SZGR genes in this pathway
MARTENS_BOUND_BY_PML_RARA_FUSION 456287All SZGR genes in this pathway
BOSCO_TH1_CYTOTOXIC_MODULE 11462All SZGR genes in this pathway


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