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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: CRMP1

Summary

GeneID

1400

Symbol

CRMP1

Synonyms

DPYSL1|DRP-1|DRP1

Description

collapsin response mediator protein 1

Locus tag

Gene type

protein-coding

Map location

4p16.1-p15

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 3

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.0069

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0004157

dihydropyrimidinase activity

TAS

8973361

GO:0005515

protein binding

IPI

15383276 |16169070

GO:0016810

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007399

nervous system development

TAS

neurite (GO term level: 5)

8973361

GO:0006139

nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

TAS

8973361

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0043025

cell soma

IEA

axon, dendrite (GO term level: 4)

GO:0030425

dendrite

IEA

neuron, axon, dendrite (GO term level: 6)

GO:0005737

cytoplasm

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
AGR2	AG2 \| GOB-4 \| HAG-2 \| XAG-2	anterior gradient homolog 2 (Xenopus laevis)	Two-hybrid	BioGRID	16169070
ALDH2	ALDH-E2 \| ALDHI \| ALDM \| MGC1806	aldehyde dehydrogenase 2 family (mitochondrial)	Two-hybrid	BioGRID	16169070
ARL15	ARFRP2 \| FLJ20051	ADP-ribosylation factor-like 15	Two-hybrid	BioGRID	16169070
AXIN1	AXIN \| MGC52315	axin 1	Two-hybrid	BioGRID	16169070
BTBD2	-	BTB (POZ) domain containing 2	Two-hybrid	BioGRID	16169070
CCDC106	HSU79303 \| ZNF581	coiled-coil domain containing 106	Two-hybrid	BioGRID	16169070
CCL18	AMAC-1 \| AMAC1 \| CKb7 \| DC-CK1 \| DCCK1 \| MIP-4 \| PARC \| SCYA18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	Two-hybrid	BioGRID	16169070
CCT7	CCT-ETA \| Ccth \| MGC110985 \| Nip7-1 \| TCP-1-eta	chaperonin containing TCP1, subunit 7 (eta)	Two-hybrid	BioGRID	16169070
CDK5RAP2	C48 \| Cep215 \| DKFZp686B1070 \| DKFZp686D1070 \| KIAA1633 \| MCPH3	CDK5 regulatory subunit associated protein 2	Two-hybrid	BioGRID	16169070
CDK5RAP3	C53 \| HSF-27 \| IC53 \| LZAP \| MST016 \| OK/SW-cl.114	CDK5 regulatory subunit associated protein 3	Two-hybrid	BioGRID	16169070
DPYSL2	CRMP2 \| DHPRP2 \| DRP-2 \| DRP2	dihydropyrimidinase-like 2	-	HPRD,BioGRID	12482610
EEF1D	EF-1D \| EF1D \| FLJ20897 \| FP1047	eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)	Two-hybrid	BioGRID	16169070
EIF2S2	DKFZp686L18198 \| EIF2 \| EIF2B \| EIF2beta \| MGC8508	eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa	Two-hybrid	BioGRID	16169070
EPN1	-	epsin 1	Two-hybrid	BioGRID	16169070
FAS	ALPS1A \| APO-1 \| APT1 \| CD95 \| FAS1 \| FASTM \| TNFRSF6	Fas (TNF receptor superfamily, member 6)	Two-hybrid	BioGRID	16169070
FTH1	FHC \| FTH \| FTHL6 \| MGC104426 \| PIG15 \| PLIF	ferritin, heavy polypeptide 1	Two-hybrid	BioGRID	16169070
FUBP1	FBP \| FUBP	far upstream element (FUSE) binding protein 1	Two-hybrid	BioGRID	16169070
FXR1	-	fragile X mental retardation, autosomal homolog 1	Two-hybrid	BioGRID	16169070
HMGB1	DKFZp686A04236 \| HMG1 \| HMG3 \| SBP-1	high-mobility group box 1	Two-hybrid	BioGRID	16169070
HNRNPH1	DKFZp686A15170 \| HNRPH \| HNRPH1 \| hnRNPH	heterogeneous nuclear ribonucleoprotein H1 (H)	Two-hybrid	BioGRID	16169070
HNRNPH3	2H9 \| FLJ34092 \| HNRPH3	heterogeneous nuclear ribonucleoprotein H3 (2H9)	Two-hybrid	BioGRID	16169070
HNRNPUL1	E1B-AP5 \| E1BAP5 \| FLJ12944 \| HNRPUL1	heterogeneous nuclear ribonucleoprotein U-like 1	Two-hybrid	BioGRID	16169070
HSPE1	CPN10 \| GROES \| HSP10	heat shock 10kDa protein 1 (chaperonin 10)	Two-hybrid	BioGRID	16169070
KLHL20	KHLHX \| KLEIP \| KLHLX \| RP3-383J4.3	kelch-like 20 (Drosophila)	Two-hybrid	BioGRID	16169070
LRRC1	FLJ10775 \| FLJ11834 \| LANO \| dJ523E19.1	leucine rich repeat containing 1	Two-hybrid	BioGRID	16169070
LSM2	C6orf28 \| G7b \| YBL026W \| snRNP	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)	Two-hybrid	BioGRID	16169070
MOBKL3	2C4D \| CGI-95 \| MGC12264 \| MOB1 \| MOB3 \| PREI3	MOB1, Mps One Binder kinase activator-like 3 (yeast)	Two-hybrid	BioGRID	16169070
MRPS12	MPR-S12 \| MT-RPS12 \| RPMS12 \| RPS12 \| RPSM12	mitochondrial ribosomal protein S12	Two-hybrid	BioGRID	16169070
NAT9	DKFZp564C103 \| EBSP	N-acetyltransferase 9 (GCN5-related, putative)	Two-hybrid	BioGRID	16169070
NDUFV2	-	NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa	Two-hybrid	BioGRID	16169070
NVL	-	nuclear VCP-like	Two-hybrid	BioGRID	16169070
PAFAH1B3	-	platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit 29kDa	Two-hybrid	BioGRID	16169070
PFN1	-	profilin 1	Two-hybrid	BioGRID	16169070
PMF1	-	polyamine-modulated factor 1	Two-hybrid	BioGRID	16169070
PPP1R8	ARD-1 \| ARD1 \| NIPP-1 \| NIPP1 \| PRO2047	protein phosphatase 1, regulatory (inhibitor) subunit 8	Two-hybrid	BioGRID	16169070
PSMD11	MGC3844 \| Rpn6 \| S9 \| p44.5	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	Two-hybrid	BioGRID	16169070
RGL2	HKE1.5 \| KE1.5 \| RAB2L	ral guanine nucleotide dissociation stimulator-like 2	Two-hybrid	BioGRID	16169070
RHOA	ARH12 \| ARHA \| RHO12 \| RHOH12	ras homolog gene family, member A	Phenotypic Suppression	BioGRID	12482610
RPA2	REPA2 \| RPA32	replication protein A2, 32kDa	Two-hybrid	BioGRID	16169070
RTN4	ASY \| NI220/250 \| NOGO \| NOGO-A \| NOGOC \| NSP \| NSP-CL \| Nbla00271 \| Nbla10545 \| Nogo-B \| Nogo-C \| RTN-X \| RTN4-A \| RTN4-B1 \| RTN4-B2 \| RTN4-C	reticulon 4	Two-hybrid	BioGRID	16169070
SAT1	DC21 \| KFSD \| SAT \| SSAT \| SSAT-1	spermidine/spermine N1-acetyltransferase 1	Two-hybrid	BioGRID	16169070
SEPHS1	MGC4980 \| SELD \| SPS \| SPS1	selenophosphate synthetase 1	Two-hybrid	BioGRID	16169070
SERPINB9	CAP-3 \| CAP3 \| PI9	serpin peptidase inhibitor, clade B (ovalbumin), member 9	Two-hybrid	BioGRID	16169070
SNRPG	MGC117317 \| SMG	small nuclear ribonucleoprotein polypeptide G	Two-hybrid	BioGRID	16169070
TFG	FLJ36137 \| TF6 \| TRKT3	TRK-fused gene	Two-hybrid	BioGRID	16169070
TK1	TK2	thymidine kinase 1, soluble	Two-hybrid	BioGRID	16169070
TRIP13	16E1BP	thyroid hormone receptor interactor 13	Two-hybrid	BioGRID	16169070
UBE2B	E2-17kDa \| HHR6B \| HR6B \| RAD6B \| UBC2	ubiquitin-conjugating enzyme E2B (RAD6 homolog)	Two-hybrid	BioGRID	16169070
ZNF24	KOX17 \| RSG-A \| ZNF191 \| ZSCAN3 \| Zfp191	zinc finger protein 24	Two-hybrid	BioGRID	16169070

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
REACTOME_DEVELOPMENTAL_BIOLOGY	396	292	All SZGR genes in this pathway
REACTOME_AXON_GUIDANCE	251	188	All SZGR genes in this pathway
REACTOME_CRMPS_IN_SEMA3A_SIGNALING	14	14	All SZGR genes in this pathway
REACTOME_SEMAPHORIN_INTERACTIONS	68	53	All SZGR genes in this pathway
DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP	332	228	All SZGR genes in this pathway
SENESE_HDAC1_TARGETS_DN	260	143	All SZGR genes in this pathway
VANHARANTA_UTERINE_FIBROID_UP	45	26	All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_G_UP	238	135	All SZGR genes in this pathway
LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN	800	473	All SZGR genes in this pathway
GUENTHER_GROWTH_SPHERICAL_VS_ADHERENT_UP	21	15	All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_DN	57	45	All SZGR genes in this pathway
SCHAEFFER_SOX9_TARGETS_IN_PROSTATE_DEVELOPMENT_DN	45	33	All SZGR genes in this pathway
BENPORATH_ES_1	379	235	All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS	1038	678	All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3	1118	744	All SZGR genes in this pathway
POMEROY_MEDULLOBLASTOMA_PROGNOSIS_UP	47	30	All SZGR genes in this pathway
PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_UP	131	87	All SZGR genes in this pathway
RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_DN	30	23	All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN	1237	837	All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_DN	504	323	All SZGR genes in this pathway
DOUGLAS_BMI1_TARGETS_UP	566	371	All SZGR genes in this pathway
AMUNDSON_GAMMA_RADIATION_RESISTANCE	20	14	All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_WITH_H3K27ME3_DN	228	114	All SZGR genes in this pathway
MOOTHA_PGC	420	269	All SZGR genes in this pathway
GOLDRATH_ANTIGEN_RESPONSE	346	192	All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP	756	494	All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP	682	440	All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP	548	370	All SZGR genes in this pathway
VERHAAK_GLIOBLASTOMA_PRONEURAL	177	132	All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_D	280	158	All SZGR genes in this pathway
PASINI_SUZ12_TARGETS_DN	315	215	All SZGR genes in this pathway
HOLLEMAN_VINCRISTINE_RESISTANCE_B_ALL_UP	38	22	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-329	167	173	m8	hsa-miR-329^brain	AACACACCUGGUUAACCUCUUU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.