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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

Gene Ranking Integration

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: CTSG

Summary

GeneID

1511

Symbol

CTSG

Synonyms

CG|MGC23078

Description

cathepsin G

See related

HGNC:2532|MIM:116830|Ensembl:ENSG00000100448|HPRD:00289|

Locus tag

-

Gene type

protein-coding

Map location

14q11.2

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

genome scan meta-analysis

Psr: 0.047

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 1

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

EML2

0.77

0.75

KLHL21

0.76

0.72

LGI3

0.75

0.72

GM2A

0.75

0.80

CYTSB

0.74

0.78

MYO7A

0.74

0.74

NAT8L

0.74

0.66

NR1H2

0.74

0.71

MYH7B

0.74

0.68

AATK

0.73

0.70

Top 10 negatively co-expressed genes

KLHL1

-0.43

-0.35

DACT1

-0.42

-0.31

AC005768.1

-0.41

-0.41

NEUROD6

-0.41

-0.38

NR2C2AP

-0.40

-0.43

POLB

-0.39

-0.44

MYCN

-0.39

-0.28

RPS3AP47

-0.39

-0.51

FRMD3

-0.39

-0.27

AC004017.1

-0.39

-0.30

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

serine-type endopeptidase activity

TAS

glutamate (GO term level: 7)

peptidase activity

IEA

-

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

proteolysis

TAS

immune response

TAS

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
CAMP	CAP18 \| CRAMP \| FALL-39 \| FALL39 \| HSD26 \| LL37	cathelicidin antimicrobial peptide	-	HPRD	11389039
CASP7	CMH-1 \| ICE-LAP3 \| MCH3	caspase 7, apoptosis-related cysteine peptidase	CatG interacts with caspase-7.	BIND	15650747
F2RL2	PAR3	coagulation factor II (thrombin) receptor-like 2	-	HPRD	11307827
F5	FVL \| PCCF	coagulation factor V (proaccelerin, labile factor)	-	HPRD	9718313
GP1BA	BSS \| CD42B \| CD42b-alpha \| GP1B \| MGC34595	glycoprotein Ib (platelet), alpha polypeptide	-	HPRD	8400294
KNG1	BDK \| KNG	kininogen 1	-	HPRD	11920276
LRP1	A2MR \| APOER \| APR \| CD91 \| FLJ16451 \| IGFBP3R \| LRP \| MGC88725 \| TGFBR5	low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)	LRP interacts with Cathepsin G.	BIND	15131125
PPBP	B-TG1 \| Beta-TG \| CTAP-III \| CTAP3 \| CTAPIII \| CXCL7 \| LA-PF4 \| LDGF \| MDGF \| NAP-2 \| PBP \| SCYB7 \| TC1 \| TC2 \| TGB \| TGB1 \| THBGB \| THBGB1	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)	-	HPRD	1387511 \|1873479
SDC1	CD138 \| SDC \| SYND1 \| syndecan	syndecan 1	-	HPRD,BioGRID	9565572
SERPINA1	A1A \| A1AT \| AAT \| MGC23330 \| MGC9222 \| PI \| PI1 \| PRO2275	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	Alpha-1 PI interacts with and inhibits cathepsin G.	BIND	15131125
SERPINA3	AACT \| ACT \| GIG24 \| GIG25 \| MGC88254	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3	Alpha-1 ACT interacts with and inhibits cathepsin G.	BIND	15131125
SERPINA3	AACT \| ACT \| GIG24 \| GIG25 \| MGC88254		-	HPRD	8849841 \|9698370 \|10512690
SERPINB13	HSHUR7SEQ \| HUR7 \| MGC126870 \| PI13 \| headpin	serpin peptidase inhibitor, clade B (ovalbumin), member 13	-	HPRD	12504904
THBS1	THBS \| TSP \| TSP1	thrombospondin 1	-	HPRD	8408036

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