Gene Page: CYP1A2

Summary
GeneID  1544
Symbol  CYP1A2
Synonyms  CP12|P3-450|P450(PA)
Description  cytochrome P450, family 1, subfamily A, polypeptide 2
See related  HGNC:2596|MIM:124060|Ensembl:ENSG00000140505|HPRD:00489|
Locus tag  -
Gene type  protein-coding
Map location  15q24.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
AssociationA combined odds ratio method (Sun et al. 2008), association studies2Link to SZGene
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005506iron ion bindingIEA-
GO:0019825oxygen bindingEXP8553685 
GO:0020037heme bindingIEA-
GO:0009055electron carrier activityTAS2813353 
GO:0032451demethylase activityIDA2813353 
GO:0046872metal ion bindingIEA-
GO:0050381unspecific monooxygenase activityIMP2813353 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0055114oxidation reductionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005792microsomeIDA2813353 
GO:0005789endoplasmic reticulum membraneEXP8553685 
GO:0005789endoplasmic reticulum membraneIEA-
GO:0005783endoplasmic reticulumIEA-
GO:0016020membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
PORCPR | CYPOR | DKFZp686G04235 | FLJ26468 | P450RP450 (cytochrome) oxidoreductaseReconstituted ComplexBioGRID9398194 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_TRYPTOPHAN_METABOLISM 4033All SZGR genes in this pathway
KEGG_LINOLEIC_ACID_METABOLISM 2916All SZGR genes in this pathway
KEGG_RETINOL_METABOLISM 6437All SZGR genes in this pathway
KEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450 7044All SZGR genes in this pathway
KEGG_DRUG_METABOLISM_CYTOCHROME_P450 7247All SZGR genes in this pathway
BIOCARTA_NUCLEARRS_PATHWAY 1512All SZGR genes in this pathway
REACTOME_BIOLOGICAL_OXIDATIONS 13991All SZGR genes in this pathway
REACTOME_XENOBIOTICS 1611All SZGR genes in this pathway
REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE 5134All SZGR genes in this pathway
REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS 7050All SZGR genes in this pathway
REACTOME_PHASE_II_CONJUGATION 7042All SZGR genes in this pathway
GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_DN 493298All SZGR genes in this pathway
WANG_CLIM2_TARGETS_UP 269146All SZGR genes in this pathway
XU_HGF_TARGETS_REPRESSED_BY_AKT1_DN 9558All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_PLASMABLAST_UP 398262All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS 882572All SZGR genes in this pathway
SU_LIVER 5532All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_DN 540340All SZGR genes in this pathway
ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_DN 274165All SZGR genes in this pathway
GRADE_COLON_CANCER_UP 871505All SZGR genes in this pathway
CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_DN 17997All SZGR genes in this pathway
CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_UP 8550All SZGR genes in this pathway
YAMASHITA_LIVER_CANCER_STEM_CELL_DN 7651All SZGR genes in this pathway
MIKKELSEN_MEF_ICP_WITH_H3K27ME3 206108All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_DN 267160All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_2 8650All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_D 280158All SZGR genes in this pathway


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