Gene Page: CYP3A5

Summary
GeneID  1577
Symbol  CYP3A5
Synonyms  CP35|P450PCN3|PCN3
Description  cytochrome P450, family 3, subfamily A, polypeptide 5
See related  HGNC:2638|MIM:605325|Ensembl:ENSG00000106258|HPRD:05617|
Locus tag  -
Gene type  protein-coding
Map location  7q21.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
CCDC570.800.74
MAMDC40.800.69
CNKSR10.790.73
VARS20.790.72
PCDH240.780.70
ADAMTS100.760.71
JMJD7-PLA2G4B0.760.73
AC013416.10.760.70
CEACAM190.760.70
PTCH20.760.72
Top 10 negatively co-expressed genes
HLA-C-0.50-0.53
FAM162A-0.49-0.50
ABCG2-0.49-0.52
AF347015.31-0.47-0.50
ACOT13-0.47-0.47
PLA2G4A-0.46-0.49
HLA-F-0.46-0.44
AF347015.27-0.46-0.49
LACTB2-0.46-0.48
SLC39A8-0.46-0.48
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005506iron ion bindingIEA-
GO:0004497monooxygenase activityIEA-
GO:0019825oxygen bindingTAS2732228 
GO:0020037heme bindingIEA-
GO:0009055electron carrier activityIEA-
GO:0046872metal ion bindingIEA-
GO:0050381unspecific monooxygenase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0008202steroid metabolic processTAS2732228 
GO:0055114oxidation reductionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005792microsomeTAS2732228 
GO:0005789endoplasmic reticulum membraneIEA-
GO:0005783endoplasmic reticulumIEA-
GO:0016020membraneIEA-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_STEROID_HORMONE_BIOSYNTHESIS 5530All SZGR genes in this pathway
KEGG_LINOLEIC_ACID_METABOLISM 2916All SZGR genes in this pathway
KEGG_RETINOL_METABOLISM 6437All SZGR genes in this pathway
KEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450 7044All SZGR genes in this pathway
KEGG_DRUG_METABOLISM_CYTOCHROME_P450 7247All SZGR genes in this pathway
KEGG_DRUG_METABOLISM_OTHER_ENZYMES 5127All SZGR genes in this pathway
REACTOME_BIOLOGICAL_OXIDATIONS 13991All SZGR genes in this pathway
REACTOME_XENOBIOTICS 1611All SZGR genes in this pathway
REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE 5134All SZGR genes in this pathway
REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS 7050All SZGR genes in this pathway
LIU_PROSTATE_CANCER_DN 481290All SZGR genes in this pathway
KIM_RESPONSE_TO_TSA_AND_DECITABINE_UP 12973All SZGR genes in this pathway
BORCZUK_MALIGNANT_MESOTHELIOMA_DN 10459All SZGR genes in this pathway
NIKOLSKY_BREAST_CANCER_7Q21_Q22_AMPLICON 7633All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN 546351All SZGR genes in this pathway
LEI_MYB_TARGETS 318215All SZGR genes in this pathway
KAAB_FAILED_HEART_ATRIUM_UP 3830All SZGR genes in this pathway
SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1 419273All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 720440All SZGR genes in this pathway
HILLION_HMGA1B_TARGETS 9268All SZGR genes in this pathway
HELLER_SILENCED_BY_METHYLATION_UP 282183All SZGR genes in this pathway
ACEVEDO_NORMAL_TISSUE_ADJACENT_TO_LIVER_TUMOR_UP 17496All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_UP 973570All SZGR genes in this pathway
ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_DN 274165All SZGR genes in this pathway
AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_UP 298174All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_DN 267160All SZGR genes in this pathway
CHICAS_RB1_TARGETS_SENESCENT 572352All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_DN 553343All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway


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